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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ASTE1 Gene

protein-coding   GIFtS: 44
GCID: GC03M130732

Asteroid Homolog 1 (Drosophila)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Asteroid Homolog 1 (Drosophila)1 2
Protein Asteroid Homolog 12

External Ids:    HGNC: 250211   Entrez Gene: 289902   Ensembl: ENSG000000345337   UniProtKB: Q2TB183   

Export aliases for ASTE1 gene to outside databases

Previous GC identifers: GC03M132216 GC03M128116


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ASTE1 Gene: 
ASTE1 (asteroid homolog 1 (Drosophila)) is a protein-coding gene. Diseases associated with ASTE1 include hailey-hailey disease, and colorectal cancer. GO annotations related to this gene include nuclease activity.

UniProtKB/Swiss-Prot: ASTE1_HUMAN, Q2TB18
Function: Possible role in EGF receptor signaling (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_005612.16  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ASTE1 gene promoter:
         SRF   C/EBPbeta   ATF-2   Nkx2-5   LCR-F1   HNF-1A   GATA-2   CRE-BP1   HNF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidASTE1 promoter sequence
   Search SABiosciences Chromatin IP Primers for ASTE1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASTE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.1   Ensembl cytogenetic band:  3q22.1   HGNC cytogenetic band: 3q21.3

ASTE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASTE1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M130732:  view genomic region     (about GC identifiers)

Start:
130,732,719 bp from pter      End:
130,746,493 bp from pter
Size:
13,775 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ASTE1_HUMAN, Q2TB18 (See protein sequence)
Recommended Name: Protein asteroid homolog 1  
Size: 679 amino acids; 77093 Da
Sequence caution: Sequence=AAF14876.1; Type=Frameshift; Positions=336; Sequence=AAH30274.2; Type=Erroneous
initiation; Sequence=AAI03710.1; Type=Erroneous initiation;
Secondary accessions: Q3MIB6 Q8N6G4 Q96JY1 Q9UHX6

Explore the universe of human proteins at neXtProt for ASTE1: NX_Q2TB18

Explore proteomics data for ASTE1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q2TB18

  • ASTE1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ASTE1 Protein Expression
    REFSEQ proteins: NP_054784.2  
    ENSEMBL proteins: 
     ENSP00000426421   ENSP00000264992   ENSP00000421019   ENSP00000423347   ENSP00000426363  
     ENSP00000425683   ENSP00000422851   ENSP00000427303  

    Human Recombinant Protein Products for ASTE1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ASTE1
    OriGene Protein Over-expression Lysate for ASTE1
    OriGene MassSpec for ASTE1 
    OriGene Custom Protein Services for ASTE1
    GenScript Custom Purified and Recombinant Proteins Services for ASTE1
    Novus Biologicals ASTE1 Protein
    Novus Biologicals ASTE1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ASTE1 


    ASTE1 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals ASTE1 Antibodies
    Abcam antibodies for ASTE1
    Cloud-Clone Corp. Antibodies for ASTE1 
    Search ThermoFisher Antibodies for ASTE1
    LSBio Antibodies in human, mouse, rat for ASTE1 

    Assay Products for ASTE1: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ASTE1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ASTE1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ASTE1 
    Cloud-Clone Corp. CLIAs for ASTE1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR026832 Asteroid
     IPR006085 XPG_DNA_repair_N

    Graphical View of Domain Structure for InterPro Entry Q2TB18

    ProtoNet protein and cluster: Q2TB18

    UniProtKB/Swiss-Prot: ASTE1_HUMAN, Q2TB18
    Similarity: Belongs to the asteroid family


    ASTE1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASTE1_HUMAN, Q2TB18
    Function: Possible role in EGF receptor signaling (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004518nuclease activity IEA--
         
    ASTE1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Aste1):
     immune system 

    ASTE1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ASTE1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ASTE1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ASTE1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ASTE1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ASTE1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ASTE1
    SwitchGear 3'UTR luciferase reporter plasmidASTE1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ASTE1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASTE1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ASTE1
    Sirion Biotech Customized adenovirus for overexpression of ASTE1

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ASTE1 (see all 9)
    OriGene ORF clones in mouse, rat for ASTE1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ASTE1 (NM_014065)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASTE1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASTE1
    Sirion Biotech Customized lentivirus for stable overexpression of ASTE1 
                         Customized lentivirus expression plasmids for stable overexpression of ASTE1 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ASTE1
    Search LifeMap BioReagents cell lines for ASTE1
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASTE1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ASTE1

    1 Interacting protein for ASTE1 (Q2TB183) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    XRCC4Q134263I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006281DNA repair IEA--

    ASTE1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ASTE1

    Search CenterWatch for drugs/clinical trials and news about ASTE1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ASTE1 gene: 
    NM_014065.2  

    Unigene Cluster for ASTE1:

    Asteroid homolog 1 (Drosophila)
    Hs.100878  [show with all ESTs]
    Unigene Representative Sequence: AK294156
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514044(uc010htm.1) ENST00000264992(uc003env.1 uc011blj.1)
    ENST00000507978 ENST00000505290 ENST00000504964 ENST00000505545 ENST00000504725
    ENST00000509060
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ASTE1
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ASTE1
    SwitchGear 3'UTR luciferase reporter plasmidASTE1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ASTE1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASTE1
    Clone
    Products:
         
    OriGene clones in human, mouse for ASTE1 (see all 9)
    OriGene ORF clones in mouse, rat for ASTE1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ASTE1 (NM_014065)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASTE1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASTE1
    Sirion Biotech Customized lentivirus for stable overexpression of ASTE1 
                         Customized lentivirus expression plasmids for stable overexpression of ASTE1 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ASTE1
    OriGene qSTAR qPCR primer pairs in human, mouse for ASTE1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ASTE1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASTE1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASTE1

    Additional mRNA sequence: 

    AF113539.1 AK027258.1 AK027806.1 AK294156.1 AK301388.1 BC030274.1 BC069265.1 BC103709.1 
    BC110616.2 

    10 DOTS entries:

    DT.443998  DT.120871848  DT.92446986  DT.100754523  DT.100688106  DT.120871865  DT.95156684  DT.120871896 
    DT.95107438  DT.97805368 

    24/78 AceView cDNA sequences (see all 78):

    AW182623 BX507326 BC069265 AA972721 AA721445 AA668674 N58008 AA767173 
    BI333667 AA025318 BQ923541 AA345255 NM_014065 BX281662 BM992874 AA361773 
    AW450093 AA811368 AA426141 AK027806 AI017204 AA648895 BM720591 AA454228 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for ASTE1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10
    SP1:                          -                                                                 -                     
    SP2:                                                  -     -     -     -                                             
    SP3:                                                                                                                  
    SP4:                    -     -                                                                                       
    SP5:                          -                                                                                       


    ECgene alternative splicing isoforms for ASTE1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ASTE1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGCAACCAA
    ASTE1 Expression
    About this image


    See ASTE1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ASTE1

    SOURCE GeneReport for Unigene cluster: Hs.100878
        SABiosciences Custom PCR Arrays for ASTE1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ASTE1
    OriGene qSTAR qPCR primer pairs in human, mouse for ASTE1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ASTE1
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASTE1
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASTE1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASTE1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ASTE1 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Aste11 , 5 asteroid homolog 1 (Drosophila)1, 5 83.21(n)1
    78.99(a)1
      9 (56.61 cM)5
    665951  NM_025651.41  NP_079927.21 
     1053953925 
    chicken
    (Gallus gallus)
    Aves ASTE11 asteroid homolog 1 (Drosophila) 51.6(n)
    45.7(a)
      420684  XM_003640740.1  XP_003640788.1 
    lizard
    (Anolis carolinensis)
    Reptilia ASTE16
    Uncharacterized protein
    52(a)
    1 ↔ 1
    6(37221307-37362972)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000036991 protein asteroid homolog 1-like 48.99(n)
    40.18(a)
      100003699  XM_001343150.4  XP_001343186.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta ast6
    asteroid
    18(a)
    1 ↔ 1
    2L(1077948-1080803)


    ENSEMBL Gene Tree for ASTE1 (if available)
    TreeFam Gene Tree for ASTE1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/156 SNPs in ASTE1 are shown (see all 156)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1920741151,2
    --130736063(+) GTTTTC/GTGTTA 1 -- int10--------
    rs1435237401,2
    --130736401(+) TTATAC/GAGTGT 1 -- int10--------
    rs2185041,2
    C,F,O,A,H--130736445(-) AATACT/CTCAGT 1 -- int121Minor allele frequency- C:0.32NS EA NA WA 2484
    rs1471775521,2
    C--130736513(+) CCTCAA/GTGTAT 1 -- int10--------
    rs67822161,2
    C,F,A--130736639(+) TGAAAC/ACCCGT 1 -- int14Minor allele frequency- A:0.38NA WA 8
    rs1440207131,2
    --130736675(+) TGGGCA/GCGGTG 1 -- int10--------
    rs1848395811,2
    --130736706(+) CTACTC/TGGAAG 1 -- int10--------
    rs113540381,2
    C--130736841(+) AAAAA-/AAA   
       AAG
    /G
    GACAA
    2 -- int1 cds1 trp32NA 4
    rs1139687301,2
    C--130736841(+) AAAAAA/GGACAA 1 -- int10--------
    rs753248101,2
    F--130736911(+) AATAAA/GAAGAT 1 -- int11Minor allele frequency- G:0.03WA 118

    HapMap Linkage Disequilibrium report for ASTE1 (130732719 - 130746493 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ASTE1:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv877498CNV Gain21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ASTE1
    DNA2.0 Custom Variant and Variant Library Synthesis for ASTE1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ASTE1:    About MalaCards
    hailey-hailey disease    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for ASTE1:
    Hailey-Hailey disease

    ASTE1 for disorders           About GeneDecksing


    Export disorders for ASTE1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ASTE1 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with ASTE1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations. (PubMed id 19503063)1 Tougeron D....Latouche J.B. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    5. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
    6. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)2 Hu R.-M.... Chen J.-L. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 28990 HGNC: 25021 AceView: HT001 Ensembl:ENSG00000034533 euGenes: HUgn28990
    ECgene: ASTE1 H-InvDB: ASTE1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ASTE1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ASTE1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ASTE1 gene:
    Search GeneIP for patents involving ASTE1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ASTE1  
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     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ASTE1
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     Regulatory tfbs in ASTE1 promoter
     Search Chromatin IP Primers for ASTE1
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     Proteins for ASTE1
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     Search ThermoFisher Antibodies for ASTE1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASTE1
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ASTE1
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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