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ASTE1 Gene

protein-coding   GIFtS: 47
GCID: GC03M130732

Asteroid Homolog 1 (Drosophila)

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Asteroid Homolog 1 (Drosophila)1 2
Protein Asteroid Homolog 12

External Ids:    HGNC: 250211   Entrez Gene: 289902   Ensembl: ENSG000000345337   UniProtKB: Q2TB183   

Export aliases for ASTE1 gene to outside databases

Previous GC identifers: GC03M132216 GC03M128116


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ASTE1 Gene:
ASTE1 (asteroid homolog 1 (Drosophila)) is a protein-coding gene. Diseases associated with ASTE1 include hailey-hailey disease, and colorectal cancer. GO annotations related to this gene include nuclease activity.

UniProtKB/Swiss-Prot: ASTE1_HUMAN, Q2TB18
Function: Possible role in EGF receptor signaling (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ASTE1 gene promoter:
         SRF   C/EBPbeta   ATF-2   Nkx2-5   LCR-F1   HNF-1A   GATA-2   CRE-BP1   HNF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidASTE1 promoter sequence
   Search Chromatin IP Primers for ASTE1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ASTE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.1   Ensembl cytogenetic band:  3q22.1   HGNC cytogenetic band: 3q21.3

ASTE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASTE1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M130732:  view genomic region     (about GC identifiers)

Start:
130,732,719 bp from pter      End:
130,746,493 bp from pter
Size:
13,775 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ASTE1_HUMAN, Q2TB18 (See protein sequence)
Recommended Name: Protein asteroid homolog 1  
Size: 679 amino acids; 77093 Da
Sequence caution: Sequence=AAF14876.1; Type=Frameshift; Positions=336; Sequence=AAH30274.2; Type=Erroneous
initiation; Sequence=AAI03710.1; Type=Erroneous initiation;
Secondary accessions: Q3MIB6 Q8N6G4 Q96JY1 Q9UHX6

Explore the universe of human proteins at neXtProt for ASTE1: NX_Q2TB18

Explore proteomics data for ASTE1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ASTE1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001275879.1  NP_054784.2  

    ENSEMBL proteins: 
     ENSP00000426421   ENSP00000264992   ENSP00000421019   ENSP00000423347   ENSP00000426363  
     ENSP00000425683   ENSP00000422851   ENSP00000427303  

    ASTE1 Human Recombinant Protein Products:

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    OriGene Purified Protein for ASTE1
    OriGene Protein Over-expression Lysate for ASTE1
    OriGene MassSpec for ASTE1
    OriGene Custom Protein Services for ASTE1
    GenScript Custom Purified and Recombinant Proteins Services for ASTE1
    Novus Biologicals ASTE1 Protein
    Novus Biologicals ASTE1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ASTE1

    ASTE1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals ASTE1 Antibodies
    Abcam antibodies for ASTE1
    Cloud-Clone Corp. Antibodies for ASTE1
    Search ThermoFisher Antibodies for ASTE1
    LSBio Antibodies in human, mouse, rat for ASTE1

    ASTE1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ASTE1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ASTE1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ASTE1
    Cloud-Clone Corp. CLIAs for ASTE1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR026832 Asteroid
     IPR006085 XPG_DNA_repair_N

    Graphical View of Domain Structure for InterPro Entry Q2TB18

    ProtoNet protein and cluster: Q2TB18

    UniProtKB/Swiss-Prot: ASTE1_HUMAN, Q2TB18
    Similarity: Belongs to the asteroid family


    ASTE1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASTE1_HUMAN, Q2TB18
    Function: Possible role in EGF receptor signaling (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004518nuclease activity IEA--
         
    ASTE1 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Aste1):
     immune system 

    ASTE1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ASTE1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ASTE1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ASTE1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ASTE1

    miRNA
    Products:
        
    miRTarBase miRNAs that target ASTE1:
    hsa-let-7f-5p (MIRT051406)

    Block miRNA regulation of human, mouse, rat ASTE1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ASTE1
    SwitchGear 3'UTR luciferase reporter plasmidASTE1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ASTE1
    Predesigned siRNA for gene silencing in human, mouse, rat ASTE1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ASTE1

    Clone
    Products:
         
    OriGene clones in human, mouse for ASTE1 (see all 9)
    OriGene ORF clones in mouse, rat for ASTE1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ASTE1 (NM_014065)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASTE1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASTE1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ASTE1
    Browse ESI BIO Cell Lines and PureStem Progenitors for ASTE1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASTE1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    endoplasmic reticulum2
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ASTE1
    Interactions:

        Search GeneGlobe Interaction Network for ASTE1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for ASTE1 (Q2TB183 ENSP000002649924) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    XRCC4Q134263I2D: score=1 
    EGFRENSP000002754934STRING: ENSP00000275493
    ERBB2ENSP000002695714STRING: ENSP00000269571
    ERBB3ENSP000002671014STRING: ENSP00000267101
    ERBB4ENSP000003422354STRING: ENSP00000342235
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006281DNA repair IEA--

    ASTE1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ASTE1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ASTE1 gene (2 alternative transcripts): 
    NM_001288950.1  NM_014065.3  

    Unigene Cluster for ASTE1:

    Asteroid homolog 1 (Drosophila)
    Hs.100878  [show with all ESTs]
    Unigene Representative Sequence: AK294156
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000514044(uc010htm.1) ENST00000264992(uc003env.1 uc011blj.1)
    ENST00000507978 ENST00000505290 ENST00000504964 ENST00000505545 ENST00000504725
    ENST00000509060
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ASTE1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ASTE1
    SwitchGear 3'UTR luciferase reporter plasmidASTE1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ASTE1
    Predesigned siRNA for gene silencing in human, mouse, rat ASTE1
    Clone
    Products:
         
    OriGene clones in human, mouse for ASTE1 (see all 9)
    OriGene ORF clones in mouse, rat for ASTE1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ASTE1 (NM_014065)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASTE1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASTE1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ASTE1
    OriGene qSTAR qPCR primer pairs in human, mouse for ASTE1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ASTE1
      QuantiTect SYBR Green Assays in human, mouse, rat ASTE1
      QuantiFast Probe-based Assays in human, mouse, rat ASTE1

    Additional mRNA sequence: 

    AF113539.1 AK027258.1 AK027806.1 AK294156.1 AK301388.1 BC030274.1 BC069265.1 BC103709.1 
    BC110616.2 

    10 DOTS entries:

    DT.443998  DT.120871848  DT.92446986  DT.100754523  DT.100688106  DT.120871865  DT.95156684  DT.120871896 
    DT.95107438  DT.97805368 

    Selected AceView cDNA sequences (see all 78):

    N46587 AA972721 AA453645 AA361773 AA648895 BX507326 BQ923541 AA668674 
    AK027806 AA767173 AA426141 AA768532 BC069265 AW182623 AA454228 AA345255 
    AW450093 AA025318 AI017204 BI333667 AI374771 NM_014065 AA811368 BM992874 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ASTE1 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10
    SP1:                          -                                                                 -                     
    SP2:                                                  -     -     -     -                                             
    SP3:                                                                                                                  
    SP4:                    -     -                                                                                       
    SP5:                          -                                                                                       


    ECgene alternative splicing isoforms for ASTE1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ASTE1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGCAACCAA
    ASTE1 Expression
    About this image


    ASTE1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    ASTE1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ASTE1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.100878
        Custom PCR Arrays for ASTE1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ASTE1
    OriGene qSTAR qPCR primer pairs in human, mouse for ASTE1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ASTE1
    QuantiTect SYBR Green Assays in human, mouse, rat ASTE1
    QuantiFast Probe-based Assays in human, mouse, rat ASTE1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASTE1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ASTE1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Aste11 , 5 asteroid homolog 1 (Drosophila)1, 5 83.26(n)1
    79.14(a)1
      9 (56.61 cM)5
    665951  NM_025651.41  NP_079927.21 
     1053953925 
    chicken
    (Gallus gallus)
    Aves ASTE11 asteroid homolog 1 (Drosophila) 51.09(n)
    44.61(a)
      420684  XM_003640740.2  XP_003640788.1 
    lizard
    (Anolis carolinensis)
    Reptilia ASTE16
    asteroid homolog 1 (Drosophila)
    51(a)
    1 ↔ 1
    6(37221307-37362972)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia aste11 asteroid homolog 1 57.38(n)
    50.84(a)
      100158587  NM_001128015.1  NP_001121487.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1000036991 protein asteroid homolog 1-like 49.24(n)
    40.48(a)
      100003699  XM_001343150.5  XP_001343186.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta ast6
    asteroid
    19(a)
    1 ↔ 1
    2L(1077948-1080803)


    ENSEMBL Gene Tree for ASTE1 (if available)
    TreeFam Gene Tree for ASTE1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ASTE1 (see all 156)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1920741151,2
    --130736063(+) GTTTTC/GTGTTA 1 -- int10--------
    rs1435237401,2
    --130736401(+) TTATAC/GAGTGT 1 -- int10--------
    rs2185041,2
    C,F,O,A,H--130736445(-) AATACT/CTCAGT 1 -- int121Minor allele frequency- C:0.32NS EA NA WA 2484
    rs1471775521,2
    C--130736513(+) CCTCAA/GTGTAT 1 -- int10--------
    rs67822161,2
    C,F,A--130736639(+) TGAAAC/ACCCGT 1 -- int14Minor allele frequency- A:0.38NA WA 8
    rs1440207131,2
    --130736675(+) TGGGCA/GCGGTG 1 -- int10--------
    rs1848395811,2
    --130736706(+) CTACTC/TGGAAG 1 -- int10--------
    rs113540381,2
    C--130736841(+) AAAAA-/AAA   
       AAG
    /G
    GACAA
    2 -- int1 cds1 trp32NA 4
    rs1139687301,2
    C--130736841(+) AAAAAA/GGACAA 1 -- int10--------
    rs753248101,2
    F--130736911(+) AATAAA/GAAGAT 1 -- int11Minor allele frequency- G:0.03WA 118

    HapMap Linkage Disequilibrium report for ASTE1 (130732719 - 130746493 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for ASTE1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv877498CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ASTE1
    DNA2.0 Custom Variant and Variant Library Synthesis for ASTE1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for ASTE1:    
    About MalaCards
    hailey-hailey disease    colorectal cancer

    1 disease from the University of Copenhagen DISEASES database for ASTE1:
    Hailey-Hailey disease

    ASTE1 for disorders           About GeneDecksing


    Export disorders for ASTE1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ASTE1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ASTE1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    3. Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations. (PubMed id 19503063)1 Tougeron D....Latouche J.B. (Mod. Pathol. 2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. Gene expression profiling in the human hypothalamus-pituitary-adrenal axis and full-length cDNA cloning. (PubMed id 10931946)2 Hu R.-M.... Chen J.-L. (Proc. Natl. Acad. Sci. U.S.A. 2000)
    7. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 28990 HGNC: 25021 AceView: HT001 Ensembl:ENSG00000034533 euGenes: HUgn28990
    ECgene: ASTE1 H-InvDB: ASTE1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ASTE1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ASTE1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ASTE1 gene:
    Search GeneIP for patents involving ASTE1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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