Aliases for ASRGL1 Gene
External Ids for ASRGL1 Gene
GeneCards Summary for ASRGL1 Gene
ASRGL1 (Asparaginase Like 1) is a Protein Coding gene. Diseases associated with ASRGL1 include central nervous system leukemia. Among its related pathways are asparagine degradation I. GO annotations related to this gene include N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity and beta-aspartyl-peptidase activity. An important paralog of this gene is TASP1.
UniProtKB/Swiss-Prot for ASRGL1 Gene
Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine.