ASPM Gene
protein-coding GIFtS : 53 GCID: GC01 M197053
asp (abnormal spindle) homolog, microcephaly associated... microcephaly, primary autosomal recessive 5, asp (abnormal... MCPH5 )
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Aliasesfor ASPM gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Asp (Abnormal Spindle) Homolog, Microcephaly Associated (Drosophila) 1 2 Asp (Abnormal Spindle)-Like, Microcephaly Associated (Drosophila)1 MCPH51 2 3 5 Microcephaly, Primary Autosomal Recessive 51 ASP1 2 Abnormal Spindle-Like Microcephaly-Associated Protein2 Calmbp11 2 Abnormal Spindle Protein Homolog3 FLJ105171 Asp Homolog3 FLJ105491
Export aliases for ASPM gene to outside databases Previous GC identifers: GC01U990488 GC01M192511 GC01M193519 GC01M194341 GC01M193785 GC01M195319 GC01M168210
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Summariesfor ASPM gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ASPM : This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.(provided by RefSeq, May 2011) UniProtKB/Swiss-Prot: ASPM_HUMAN, Q8IZT6 Function : Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferentialrole in regulating neurogenesis Gene Wiki entry for ASPM
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Genomic Viewsfor ASPM gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_004487.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ASPM gene promoter:AML1a E2F-1 E2F FOXD3 POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 GATA-1 Other transcription factors Search SABiosciences Chromatin IP Primers for ASPM Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1q31 Ensembl cytogenetic band: 1q31.3 HGNC cytogenetic band: 1q31 ASPM Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01M197053: view genomic region
(about GC identifiers )
Start: 197,053,257 bp from pter End:
197,115,824 bp from pter
Size: 62,568 bases Orientation:
minus strand
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Proteinsfor ASPM gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ASPM_HUMAN, Q8IZT6 See
protein sequence )Recommended Name: Size : 3477 amino acids; 409800 DaSubcellular location : Cytoplasm (By similarity). Cytoplasm, cytoskeleton, spindle. Nucleus (By similarity). Note=Thenuclear-cytoplasmic distribution could be regulated by the availability of calmodulin (By similarity). Localizes to spindle poles during mitosis
Sequence caution : Sequence=AAH34607.1; Type=Erroneous initiation; Sequence=BAA91676.1; Type=Erroneous initiation;Secondary accessions : Q4G1H1 Q5VYL3 Q86UX4 Q8IUL2 Q8IZJ7 Q8IZJ8 Q8IZJ9 Q8N4D1 Q9NVS1 Q9NVT6Alternative splicing : 2 isoforms : Q8IZT6-1 Q8IZT6-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ASPM: NX_Q8IZT6 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8IZT6 ASPM Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins (2 alternative transcripts): NP_001193775.1 NP_060606.3 ENSEMBL proteins: ENSP00000356379 ENSP00000356378 ENSP00000294732 Human Recombinant Protein Products for ASPM: Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view) : About this table
About GeneDecksing ASPM Antibody Products: Assay Products for ASPM:
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Protein
Domains /for ASPM gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8IZT6 ProtoNet protein and cluster: Q8IZT6
2 Blocks protein families : IPB000048 IPB001715 UniProtKB/Swiss-Prot: ASPM_HUMAN, Q8IZT6 Similarity : Contains 2 CH (calponin-homology) domainsSimilarity : Contains 39 IQ domains
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Functionfor ASPM gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: ASPM_HUMAN, Q8IZT6 Function : Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferentialrole in regulating neurogenesis
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005516 calmodulin binding
IEA --
About GeneDecksing Phenotypes: 1 GenomeRNAi human phenotype for ASPM :5 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Aspm) :About GeneDecksing Animal Models: Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): ASPM (NM_018136 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ASPM Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ASPM
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASPM
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Pathways & Interactionsfor ASPM gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ASPM STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/48 Interacting proteins for ASPM (Q8IZT6 3 ENSP00000356379 4 via UniProtKB, MINT, STRING , and/or I2D (see all 48 )About this table Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12 ): About this table
About GeneDecksing
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Drugs & Compoundsfor ASPM gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for ASPM ASPM
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Transcriptsfor ASPM gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ASPM gene (2 alternative transcripts): NM_001206846.1 NM_018136.4 Unigene Cluster for ASPM:
Asp (abnormal spindle) homolog, microcephaly associated (Drosophila) Hs.121028 [show with all ESTs ] Unigene Representative Sequence: NM_018136 3 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000367409 (uc001gtu.3 uc001gtw.4 ) ENST00000367408 ENST00000294732 (uc001gtv.3 )Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 3 )human mouse rat OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): ASPM (NM_018136 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ASPM Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ASPM
Additional cDNA sequence: AF509326.1 AK001379.1 AK001380.1 AK001411.1 AK095892.1 AK125107.1 AK226178.1 AY099890.1 AY099891.1 AY099892.1 AY099893.1 AY101201.1 AY367065.1 AY971955.1 AY971956.1 AY971957.1 BC015396.2 BC034607.1 BC040439.1 BX648804.1
7 DOTS entries : DT.211122 DT.100783368
DT.427161 DT.100783370 DT.40219070 DT.102828077 DT.121330049 24/130 AceView cDNA sequences (see all 130 ):
AA287540 BC034607 AA642440 BM698701 BG035713 AI085761 BU508209 BP365385 AY099893 AI016489 AA287875 AA969404 NM_018136 AU141032 AY099890 AA827767 AI126836 AI214278 CB123979 AY099891 AY367065 AI248866 BC040439 AY099892 GeneLoc Exon Structure
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Expression for ASPM gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ASPM expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TAATAAACTAAbout this image ASPM expression in embryonic tissues and stem cells About this table
See ASPM Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ASPM SOURCE GeneReport for Unigene cluster: Hs.121028 SABiosciences Custom PCR Arrays for ASPM Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASPM
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Orthologsfor ASPM gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for ASPM gene from 9/22 species (see all 22 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Aspm1 5
asp (abnormal spindle)-like, microcephaly associated more 1, 5
74.41(n) 1 65.92(a) 1
1 (61.45 cM) 5 12316 1 NM_009791.4 1 NP_033921.3 1 139454773 5
chicken Aves ASPM1
asp (abnormal spindle) homolog, microcephaly associated more
61.33(n) 53.25(a)
424354 XM_422197.3 XP_422197.3
lizard Reptilia ASPM6
--
46(a)
1 ↔ 1
GL343432.1(254266-288516)
African clawed frog Amphibia Xl.77782
Xenopus laevis transcribed sequence with weak similarity more
74.25(n)
CF289446.1
zebrafish Actinopterygii Dr.194632
Transcribed sequence with weak similarity to protein more
72.06(n)
BM141409.1
fruit fly Insecta asp6
abnormal spindle
21(a)
1 ↔ 1
3R(20579625-20586235)
worm Secernentea aspm-16
mammalian ASPM (Abnormal SPindles and primary Micr... 14(a)
1 ↔ 1
I(9221819-9226379)
thale cress eudicotyledons AT4G218206
binding / calmodulin binding protein
21(a)
1 ↔ 1
4(11577524-11584053)
rice Liliopsida --
IQ calmodulin-binding motif family protein, expres... 20(a)
1 ↔ 1
7(19942783-19950062)
ENSEMBL Gene Tree for ASPM (if available)TreeFam Gene Tree for ASPM (if available)
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Paralogsfor ASPM gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section
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Genomic Variantsfor ASPM gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 1 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for ASPM (197053257 - 197115824 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for ASPM 2 CNVs 2343 3326 Human Gene Mutation Database (HGMD) : ASPM SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor ASPM gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 605481 OMIM disorders : 608716 UniProtKB/Swiss-Prot: ASPM_HUMAN, Q8IZT6 Defects in ASPM are the cause of microcephaly primary type 5 (MCPH5) [MIM:608716]; also known as true microcephaly or microcephaly vera. Microcephaly is defined as a head circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. Despite this marked reduction in size, the gyral pattern is relatively well preserved, with no major abnormality in cortical architecture. Primary microcephaly is further defined by the absence of other syndromic features or significant neurological deficits. This entity is inherited as autosomal recessive trait 20/21 (see all 21 ): About MalaCards microcephaly, primary autosomal recessive, 5, with or without simplified gyral pattern microcephaly primary autosomal recessive microcephaly age related macular degeneration macular degeneration oculocerebrorenal syndrome intellectual disability seckel syndrome malignant glioma angelman syndrome hepatitis c medulloblastoma hepatocellular carcinoma seizures breast cancer glioblastoma hepatitis cerebritis schizophrenia carcinoma 3 diseases from the University of Copenhagen DISEASES database for ASPM :Microcephaly Intellectual disability Oculocerebrorenal syndrome 3 Novoseek disease relationships for ASPM gene About this table
GeneTests: ASPM Primary Autosomal Recessive Microcephaly Human Genome Epidemiology (HuGE) Navigator: ASPM (8 documents) Export disorders for ASPM gene to outside databases
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Publicationsfor ASPM gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ASPM gene, integrated from 9 sources (see all 82 ):(articles sorted by number of sources associating them with ASPM) Utopia : connect your pdf to the dynamic
The microcephaly ASPM gene is expressed in proliferating tissues and encodes for a mitotic spindle protein. (PubMed id 15972725) 1 , 2 , 9(2005) ASPM is a major determinant of cerebral cortical size. (PubMed id 12355089) 1 , 2 , 9(2002) Protein-truncating mutations in ASPM cause variable reduction in brain size. (PubMed id 14574646) 1 , 2 , 9(2003) A common SNP of MCPH1 is associated with cranial volume variation in Chinese population. (PubMed id 18204051) 1 , 2 (2008) Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983) 1 , 2 (2006) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 , 2 (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) Evolution of the human ASPM gene, a major determinant of brain size. (PubMed id 14704186) 1 , 2 (2003) A fifth locus for primary autosomal recessive microcephaly maps to chromosome 1q31. (PubMed id 11078481) 1 , 3(2000) Expression analysis of the autosomal recessive primary microcephaly genes MCPH1 (microcephalin) and MCPH5 (ASPM, abnormal spindle-like, microcephaly associated) in human malignant gliomas. (PubMed id 18636190) 1 , 9(2008)
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External Searches for ASPM gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ASPM gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing ASPM gene
(According to HUGE )
About This Section --
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Specialized Databases showing ASPM gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for ASPM Pharmacogenomics, SNPs, Pathways GeneReviews http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ASPM
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About This Section Patent Information for ASPM gene: ASPM GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ASPM gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
Browse OriGene Antibodies OriGene shRNA RFP for ASPM OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ASPM OriGene 3'-UTR Clone for ASPM OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ASPM OriGene Custom Protein Services for ASPM OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ASPM QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
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ASPM Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASPM
Search ThermoFisher Antibodies for ASPM
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ASPM
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Browse Tocris compounds for 
Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Anatomical Compartment 
Negative
Selective marker
Curated
In-situ hybridization
