ASPH Gene
protein-coding GIFtS: 54
GCID: GC08M062465
|
|
aspartate beta-hydroxylase
| |
Aliases
for ASPH gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Aspartate Beta-Hydroxylase1 2 3 | | A Beta H-J-J2 | | HAAH1 2 5 | | Aspartyl/Asparaginyl Beta-Hydroxylase2 | | BAH1 2 | | Aspartyl/Asparaginyl-Beta-Hydroxylase1 | | CASQ2BP11 2 | | Cardiac Junctin2 | | JCTN1 2 | | Humbug1 | | Peptide-Aspartate Beta-Dioxygenase2 3 | | Junctate1 | | ASP Beta-Hydroxylase2 3 | | Junctin1 | | AAH2 | | EC 1.14.11.163 |
Export aliases for ASPH gene to outside databasesPrevious GC identifers: GC08M061782 GC08M062355 GC08M062138 GC08M062578 GC08M057901 |
Summaries
for ASPH gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ASPH:
This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters andundergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near theirN-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. Thelongest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylatesaspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, includingprotein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarilyin the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic andsarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodinereceptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have beenimplicated in metastasis. (provided by RefSeq, Sep 2009)
UniProtKB/Swiss-Prot: ASPH_HUMAN, Q12797Function: Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF)domains of a number of proteinsFunction: Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membranejunctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells
Gene Wiki entry for ASPH
|
Genomic Views
for ASPH gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_008183.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ASPH gene promoter:
c-Fos GR AP-1 JunB GR-beta Fra-1 FosB GATA-2 GR-alpha c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for ASPH
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASPH |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8q12.1 Ensembl cytogenetic band: 8q12.3 HGNC cytogenetic band: 8q12.1ASPH Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M062465: view genomic region
(about GC identifiers)
Start:
|
62,413,115 bp from pter |
End:
|
62,627,199 bp from pter |
Size:
|
214,085 bases |
Orientation:
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minus strand |
|
Proteins
for ASPH gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ASPH_HUMAN, Q12797 (See
protein sequence)Recommended Name: Aspartyl/asparaginyl beta-hydroxylase Size: 758 amino acids; 85863 Da
Cofactor: Iron
Subunit: Monomer (By similarity). Isoform 8 interacts with ORAI1 and STIM1
Subcellular location: Isoform 1: Endoplasmic reticulum membrane; Single-pass type II membrane protein
Subcellular location: Isoform 8: Endoplasmic reticulum membrane; Single-pass type II membrane protein
1 PDB 3D structure from  and Proteopedia  for ASPH:3RCQ (3D)
Secondary accessions: A6NDF4 A6NHI2 B4DIC9 B7ZM95 E5RGP5 Q6NXR7 Q8TB28 Q9H291 Q9H2C4 Q9NRI0 Q9NRI1Q9Y4J0Alternative splicing: 9 isoforms: Q12797-1 Q12797-2 Q12797-3 Q12797-4 Q12797-5 Q12797-6 Q12797-7 Q12797-8 Q12797-9 (Glycosylated on Asn-64)Explore the universe of human proteins at neXtProt for ASPH: NX_Q12797
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q12797
ASPH Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (12 alternative transcripts):
NP_001158222.1 NP_001158223.1 NP_001158224.1 NP_001158225.1 NP_001158226.1 NP_001158227.1 NP_001158228.1 NP_004309.2 NP_064549.1 NP_115855.1 NP_115856.1 NP_115857.1
ENSEMBL proteins: ENSP00000368767 ENSP00000429718 ENSP00000430516 ENSP00000348841 ENSP00000427823 ENSP00000429286 ENSP00000430245 ENSP00000429954 ENSP00000429160 ENSP00000427877 ENSP00000429743 ENSP00000373856 ENSP00000436188 ENSP00000368762 ENSP00000428060 ENSP00000437864 ENSP00000394013
Human Recombinant Protein Products for ASPH:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
ASPH for ontologies About GeneDecksing
ASPH Antibody Products:
Assay Products for ASPH: |
Protein
Domains /
Families
for ASPH gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ASPH for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q12797ProtoNet protein and cluster: Q12797 UniProtKB/Swiss-Prot: ASPH_HUMAN, Q12797Similarity: Belongs to the aspartyl/asparaginyl beta-hydroxylase familySimilarity: Contains 4 TPR repeats |
Function
for ASPH gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: ASPH_HUMAN, Q12797Function: Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF)domains of a number of proteinsFunction: Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membranejunctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cellsCatalytic activity: Peptide L-aspartate + 2-oxoglutarate + O(2) = peptide 3-hydroxy-L-aspartate + succinate + CO(2) Enzyme Number (IUBMB): EC 1.14.11.161
Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
ASPH for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for ASPH:
9 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Asph):
ASPH for phenotypes About GeneDecksing
Animal Models:
Mouse knock-outs for ASPH: Asphtm1Egk Asphtm1Jed
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ASPH (see all 22)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ASPH (see all 13)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 12): ASPH (NM_032466) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ASPH | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASPH |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASPH |
|
Pathways & Interactions
for ASPH gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ASPH
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/14 Interacting proteins for ASPH (Q127973 ENSP000003687674) via UniProtKB, MINT, STRING, and/or I2D (see all 14)About this table
Gene Ontology (GO): 5/20 biological process terms (GO ID links to tree view) (see all 20): About this table
ASPH for ontologies About GeneDecksing
|
Drugs & Compounds
for ASPH gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ASPH for compounds About GeneDecksing
 Browse Tocris compounds for ASPH
6 HMDB Compounds for ASPH About this table
2 DrugBank Compounds for ASPH About this table
3 Novoseek chemical compound relationships for ASPH gene About this table
Search CenterWatch for drugs/clinical trials and news about ASPH
|
Transcripts
for ASPH gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ASPH gene (12 alternative transcripts): NM_001164750.1 NM_001164751.1 NM_001164752.1 NM_001164753.1 NM_001164754.1 NM_001164755.1 NM_001164756.1 NM_004318.3 NM_020164.4 NM_032466.3 NM_032467.3 NM_032468.4 Unigene Cluster for ASPH: Aspartate beta-hydroxylase Hs.332422 [show with all ESTs]Unigene Representative Sequence: NM_00431818/30 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 30): ENST00000379454(uc003xuo.2) ENST00000521909 ENST00000524173 ENST00000521499
ENST00000522349 ENST00000523897 ENST00000523927 ENST00000522919 ENST00000356457(uc003xum.3 uc003xun.3 uc011lek.2)
ENST00000519234 ENST00000518068 ENST00000517903(uc003xul.3 uc011lei.2 uc011lej.2 uc011leh.2)
ENST00000517847 ENST00000518441 ENST00000522835 ENST00000519678 ENST00000519264
ENST00000518306
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ASPH (see all 22)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ASPH (see all 13)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 12): ASPH (NM_032466) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ASPH | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASPH |
Additional cDNA sequence: AF086211.1 AF184241.1 AF224468.1 AF224469.1 AF289489.1 AF306765.1 AF339775.1 AK096383.1 AK291836.1 AK295528.1 AK298577.1 AK304314.1 BC015518.2 BC025236.1 BC066929.1 BC142967.1 BC144362.1 BC144363.1 EU718494.1 FJ461473.1 S83325.1 U03109.1 24/43 DOTS entries (see all 43): DT.95137827 DT.100828247 DT.75142168 DT.91747937 DT.100717633 DT.97791318 DT.121476279 DT.91806352 DT.100828251 DT.100031688 DT.75144670 DT.121476264 DT.100828250 DT.101983609 DT.100031678 DT.91771048 DT.91838855 DT.121476378 DT.91771045 DT.92395560 DT.110348 DT.121476242 DT.95137817 DT.97860729 24/558 AceView cDNA sequences (see all 558): BM763240 BM795015 BE671112 AA593699 BF149386 CA416660 BX111251 CR600401 AI401528 BU175716 CA442770 AI473329 AI963192 BQ181232 CK724966 AI381305 BM983246 AI873725 BQ318605 AA676497 AL694159 BE018154 CB107396 AI636729
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ASPH About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 |
|---|
|
| SP1: | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | | | - | | | | - | | - | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | - | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | - | | | | - | | - | | - | | - | | - | | | | |
| SP5: | | | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ASPH
|
Expression
for ASPH gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ASPH expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGTACTCGAT
About this image
See ASPH Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ASPH
SOURCE GeneReport for Unigene cluster: Hs.332422
UniProtKB/Swiss-Prot: ASPH_HUMAN, Q12797Tissue specificity: Isoform 1 is detected in all tissues tested. Isoform 8 is mainly expressed in pancreas, heart,brain, kidney and liver. Isoform 8 is expressed in kidney (at protein level)
SABiosciences Custom PCR Arrays for ASPH
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ASPH
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ASPH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASPH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASPH | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASPH |
Orthologs
for ASPH gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ASPH gene from 7/18 species (see all 18) About this table
ENSEMBL Gene Tree for ASPH (if available)
TreeFam Gene Tree for ASPH (if available) |
Paralogs
for ASPH gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ASPH gene
- ASPHD22 ASPHD12
1 SIMAP similar gene for ASPH using alignment to 13 protein entries: ASPH_HUMAN (see all proteins):ASPHD1
ASPH for paralogs About GeneDecksing
|
Genomic Variants
for ASPH gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ASPH (62413115 - 62627199 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for ASPH
2 CNVs: 95470 65150 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ASPH |
|
Disorders
/ Diseases
for ASPH gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ASPH for disorders About GeneDecksing
OMIM gene information: 600582
OMIM disorders: --
20/25  diseases for ASPH (see all 25): About MalaCardscatecholaminergic polymorphic ventricular tachycardia regular astigmatism ventricular tachycardia non-small cell lung carcinoma
malignant hyperthermia malignant hyperthermia susceptibility bile duct cancer conn's syndrome
adrenal hyperplasia intrahepatic cholangiocarcinoma alcoholic hepatitis cholangiocarcinoma
bipolar disorder hepatocellular carcinoma lung carcinoma alcoholism
colon cancer gastric cancer myopathy carcinoma
1 disease from the University of Copenhagen DISEASES database for ASPH:Regular astigmatism 5 Novoseek disease relationships for ASPH gene About this table
Export disorders for ASPH gene to outside databases
|
Publications
for ASPH gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ASPH gene, integrated from 9 sources (see all 96):
(articles sorted by number of sources associating them with ASPH) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- cDNA cloning and characterization of human cardiac junctin. (PubMed id 10974562)1, 2, 3, 9 Lim K.Y.... Kim D.H. (2000)
- Cloning and characterization of the human gene encoding aspartyl beta-hydroxylase. (PubMed id 7821814)1, 2, 3, 9 Korioth F.... Frey J. (1994)
- Aspartyl beta -hydroxylase (Asph) and an evolutionarily conserved isoform of Asph missing the catalytic domain share exons with junctin. (PubMed id 10956665)1, 2, 9 Dinchuk J.E....Friedman P.A. (2000)
- Molecular cloning of junctin from human and developing rabbit heart. (PubMed id 10767180)1, 2, 9 Wetzel G.T.... Chen F. (2000)
- Molecular cloning, expression, functional characterization, chromosomal localization, and gene structure of junctate, a novel integral calcium binding protein of sarco(endo)plasmic reticulum membrane. (PubMed id 11007777)1, 2, 9 Treves S.... Zorzato F. (2000)
- Junctate is a Ca2+-sensing structural component of Ora i1 and stromal interaction molecule 1 (STIM1). (PubMed id 22586105)1, 2 Srikanth S....Gwack Y. (2012)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Overexpression of human aspartyl(asparaginyl)beta-hydroxylase in hepatocellular carcinoma and cholangiocarcinoma. (PubMed id 8823296)1, 2 Lavaissiere L.... Friedman P.A. (1996)
- Complex formation between junctin, triadin, calsequestrin, and the ryanodine receptor. Proteins of the cardiac junctional sarcoplasmic reticulum membrane. (PubMed id 9287354)1, 9 Zhang L....Jones L.R. (1997)
- The role of calsequestrin, triadin, and junctin in conferring cardiac ryanodine receptor responsiveness to luminal calcium. (PubMed id 15041652)1, 9 Gyorke I....Gyorke S. (2004)
|
External Searches for ASPH gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ASPH gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ASPH gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ASPH gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for ASPH gene:
Search GeneIP for patents involving ASPH
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ASPH gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ASPH | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ASPH | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ASPH | | | OriGene Protein Over-expression Lysate for ASPH | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ASPH | | OriGene 3'-UTR Clone for ASPH | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ASPH | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ASPH | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ASPH | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ASPH | | OriGene Custom Protein Services for ASPH | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ASPH | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ASPH | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASPH | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASPH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASPH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASPH |
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| | | | Search Tocris compounds for ASPH |
| |  |  |  |  | | | | | | Recombinant Protein for ASPH |
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 | | | ASPH Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASPH |
|  |  |  |  | | | | Search ThermoFisher Antibodies for ASPH |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASPH |
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