Aliases for ASPH Gene
Aliases for ASPH Gene
External Ids for ASPH Gene
- HGNC: 757
- Entrez Gene: 444
- Ensembl: ENSG00000198363
- OMIM: 600582
- UniProtKB: Q12797
Previous GeneCards Identifiers for ASPH Gene
- GC08M061782
- GC08M062355
- GC08M062138
- GC08M062465
- GC08M062578
- GC08M057901
Summaries for ASPH Gene
-
This gene is thought to play an important role in calcium homeostasis. The gene is expressed from two promoters and undergoes extensive alternative splicing. The encoded set of proteins share varying amounts of overlap near their N-termini but have substantial variations in their C-terminal domains resulting in distinct functional properties. The longest isoforms (a and f) include a C-terminal Aspartyl/Asparaginyl beta-hydroxylase domain that hydroxylates aspartic acid or asparagine residues in the epidermal growth factor (EGF)-like domains of some proteins, including protein C, coagulation factors VII, IX, and X, and the complement factors C1R and C1S. Other isoforms differ primarily in the C-terminal sequence and lack the hydroxylase domain, and some have been localized to the endoplasmic and sarcoplasmic reticulum. Some of these isoforms are found in complexes with calsequestrin, triadin, and the ryanodine receptor, and have been shown to regulate calcium release from the sarcoplasmic reticulum. Some isoforms have been implicated in metastasis. [provided by RefSeq, Sep 2009]
GeneCards Summary for ASPH Gene
ASPH (Aspartate Beta-Hydroxylase) is a Protein Coding gene. Diseases associated with ASPH include Traboulsi Syndrome and Regular Astigmatism. Among its related pathways are Ion channel transport and Cardiac conduction. GO annotations related to this gene include calcium ion binding and ion channel binding. An important paralog of this gene is ASPHD1.
UniProtKB/Swiss-Prot for ASPH Gene
-
Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.
-
Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ASPH Gene
Genomics for ASPH Gene
Regulatory Elements for ASPH Gene
Enhancers for ASPH Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around ASPH on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ASPH Gene
- Chromosome:
- 8
- Start:
- 61,500,556 bp from pter
- End:
- 61,714,640 bp from pter
- Size:
- 214,085 bases
- Orientation:
- Minus strand
Genomic View for ASPH Gene
Genes around ASPH on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q12.3 by Ensembl
- 8q12.1 by Entrez Gene
- 8q12.1 by HGNC
ASPH Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ASPH Gene
Proteins for ASPH Gene
-
Protein details for ASPH Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q12797-ASPH_HUMAN
- Recommended name:
- Aspartyl/asparaginyl beta-hydroxylase
- Protein Accession:
- Q12797
- A6NDF4
- A6NHI2
- B4DIC9
- B4E2K4
- B7ZM95
- E5RGP5
- F5H667
- Q6NXR7
- Q8TB28
- Q9H291
- Q9H2C4
- Q9NRI0
- Q9NRI1
- Q9Y4J0
Protein attributes for ASPH Gene
- Size:
- 758 amino acids
- Molecular mass:
- 85863 Da
- Cofactor:
- Name=Fe cation; Xref=ChEBI:CHEBI:24875;
- Quaternary structure:
-
- Monomer (By similarity). Isoform 8 interacts with ORAI1 and STIM1. Isoform 4 interacts with CASQ2.
Protein Expression for ASPH Gene
Post-translational modifications for ASPH Gene
Other Protein References for ASPH Gene
- ENSEMBL proteins:
-
- ENSP00000348841
- ENSP00000368762
- ENSP00000373856
- ENSP00000394013
- ENSP00000427823
- ENSP00000427877
- ENSP00000428060
- ENSP00000429160
- ENSP00000429286
- ENSP00000429718
- ENSP00000429743
- ENSP00000429954
- ENSP00000430245
- ENSP00000430516
- ENSP00000436188
- ENSP00000437864
- ENSP00000478706
- ENSP00000479830
- ENSP00000479945
- ENSP00000483443
- ENSP00000368767
- REFSEQ proteins:
Antibody Products
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-
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-
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-
Santa Cruz Biotechnology (SCBT) Antibodies for ASPH
Protein Products
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-
Cloud-Clone Corp. Proteins for ASPH
- antibodies-online Proteins for ASPH: See all 20
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No data available for DME Specific Peptides for ASPH Gene
Domains & Families for ASPH Gene
Protein Domains for ASPH Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for ASPH Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q12797UniProtKB/Swiss-Prot:
ASPH_HUMAN :- Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
- Contains 4 TPR repeats.
- Family:
-
- Belongs to the aspartyl/asparaginyl beta-hydroxylase family.
- Similarity:
-
- Contains 4 TPR repeats.
No data available for Gene Families for ASPH Gene
Function for ASPH Gene
Molecular function for ASPH Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Peptide L-aspartate + 2-oxoglutarate + O(2) = peptide 3-hydroxy-L-aspartate + succinate + CO(2).
- UniProtKB/Swiss-Prot Function:
- Isoform 1: specifically hydroxylates an Asp or Asn residue in certain epidermal growth factor-like (EGF) domains of a number of proteins.
- UniProtKB/Swiss-Prot Function:
- Isoform 8: membrane-bound Ca(2+)-sensing protein, which is a structural component of the ER-plasma membrane junctions. Isoform 8 regulates the activity of Ca(+2) released-activated Ca(+2) (CRAC) channels in T-cells.
Enzyme Numbers (IUBMB) for ASPH Gene
Phenotypes for ASPH Gene
- MGI mutant phenotypes for ASPH:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for ASPH:
-
- Increased vaccinia virus (VACV) infection
- Decreased hepcidin::fluc mRNA expression
- Synthetic lethal with Ras
- Decreased ionizing radiation sensitivity
- Decreased NF-kappaB reporter expression
- Resistant to vaccinia virus (VACV-A4L) infection
- Increased shRNA abundance (Z-score > 2)
- Decreased shRNA abundance (Z-score < -2)
- Decreased shRNA abundance
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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CRISPR Products
-
OriGene CRISPR knockouts for ASPH
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASPH
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miRNA for ASPH Gene
- miRTarBase miRNAs that target ASPH
-
- hsa-mir-155-5p (MIRT020908)
- hsa-mir-215-5p (MIRT024363)
- hsa-mir-192-5p (MIRT026731)
- hsa-mir-16-5p (MIRT031802)
- hsa-mir-921 (MIRT403517)
- hsa-mir-1-3p (MIRT437918)
- mmu-mir-1a-3p (MIRT437919)
- rno-mir-1-3p (MIRT437920)
- hsa-mir-1225-5p (MIRT457127)
- hsa-mir-939-5p (MIRT457128)
- hsa-mir-1343-5p (MIRT457129)
- hsa-mir-6851-5p (MIRT457130)
- hsa-mir-3689d (MIRT457131)
- hsa-mir-4722-5p (MIRT457132)
- hsa-mir-6081 (MIRT457133)
- hsa-mir-7854-3p (MIRT457134)
- hsa-mir-8069 (MIRT457135)
- hsa-mir-4699-5p (MIRT457136)
- hsa-mir-4459 (MIRT457137)
- hsa-mir-6165 (MIRT457138)
- hsa-mir-4506 (MIRT457139)
- hsa-mir-4662b (MIRT457140)
- hsa-mir-4647 (MIRT457141)
- hsa-mir-4426 (MIRT457142)
- hsa-mir-6734-5p (MIRT483701)
- hsa-mir-4728-5p (MIRT483702)
- hsa-mir-6073 (MIRT483703)
- hsa-mir-3175 (MIRT483704)
- hsa-mir-8085 (MIRT483705)
- hsa-mir-6731-5p (MIRT483706)
- hsa-mir-6738-5p (MIRT483707)
- hsa-mir-5194 (MIRT483708)
- hsa-mir-423-5p (MIRT483709)
- hsa-mir-1914-3p (MIRT483710)
- hsa-mir-3184-5p (MIRT483711)
- hsa-mir-3174 (MIRT483712)
- hsa-mir-6755-5p (MIRT483713)
miRNA Products
- Search ViGene Biosciences for ASPH
Inhibitory RNA Products
Clone Products
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-
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- XM_005251248
- XM_005251249
- XM_005251250
- NM_032466
- NM_032468
- NM_020164
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- NM_001164753
- NM_001164755
- NM_001164752
- NM_001164754
- NM_004318
- NM_001164756
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Cell Line Products
Flow Cytometry Products
No data available for Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for ASPH Gene
Localization for ASPH Gene
Subcellular locations from UniProtKB/Swiss-Prot for ASPH Gene
- Isoform 1: Endoplasmic reticulum membrane; Single-pass type II membrane protein.
- Isoform 4: Sarcoplasmic reticulum membrane; Single-pass type II membrane protein.
- Isoform 8: Endoplasmic reticulum membrane; Single-pass type II membrane protein.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| plasma membrane | 5 |
| cytosol | 2 |
| nucleus | 2 |
| mitochondrion | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | -- |
Pathways & Interactions for ASPH Gene
More details on SuperPathways for ASPH| Superpath | Contained pathways | ||
|---|---|---|---|
| 1 | Cardiac conduction |
.38
|
|
| 2 | Ion channel transport | ||
| 3 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds |
Pathways by source for ASPH Gene
6 Reactome pathways for ASPH Gene
Interacting Proteins for ASPH Gene
Selected Interacting proteins:
ENSP00000368767
Q12797-ASPH_HUMAN
for ASPH Gene via
STRING
UniProtKB
I2D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006936 | muscle contraction | TAS | 10974562 |
| GO:0007389 | pattern specification process | IEA | -- |
| GO:0008285 | negative regulation of cell proliferation | IEA | -- |
| GO:0010524 | positive regulation of calcium ion transport into cytosol | IDA | 21062895 |
| GO:0010649 | regulation of cell communication by electrical coupling | TAS | 22123818 |
No data available for SIGNOR curated interactions for ASPH Gene
Drugs & Compounds for ASPH Gene
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| carbon dioxide |
|
124-38-9 |
|
|||
| Fe2+ |
|
15438-31-0 |
|
|||
| Oxoglutaric acid |
|
328-50-7 |
|
|||
| oxygen |
|
7782-44-7 |
|
Transcripts for ASPH Gene
mRNA/cDNA for ASPH Gene
- (27) REFSEQ mRNAs :
- (22) Additional mRNA sequences :
- (558) Selected AceView cDNA sequences:
- (30) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ASPH Gene
CRISPR Products
-
OriGene CRISPR knockouts for ASPH
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASPH
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miRNA Products
- Search ViGene Biosciences for ASPH
Inhibitory RNA Products
Clone Products
- OriGene clones in human for ASPH
- OriGene ORF clones in human,mouse for ASPH
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
-
GenScript: Next-day shipping cDNA clones in your preferred vector
- XM_005251235
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- XM_005251244
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- XM_005251247
- XM_005251248
- XM_005251249
- XM_005251250
- NM_032466
- NM_032468
- NM_020164
- NM_001164750
- NM_001164751
- NM_032467
- NM_001164753
- NM_001164755
- NM_001164752
- NM_001164754
- NM_004318
- NM_001164756
- Sino Biological Human cDNA Clone for ASPH
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ASPH
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | ||||||||||||||||||||||
| SP2: | - | - | - | - | |||||||||||||||||||||
| SP3: | - | - | |||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | |||||||||||||||||||
| SP5: | - |
Expression for ASPH Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Blood (Hematopoietic System)
- Proerythroblasts Hematopoietic Bone Marrow
- Eye (Sensory Organs)
- Adipose (Muscoskeletal System)
-
Skeletal Muscle (Muscoskeletal System)
This gene is overexpressed in Nasopharynx (16.3), Bone (10.5), and Adipocyte (6.5).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ASPH Gene
SOURCE GeneReport for Unigene cluster for ASPH Gene Hs.332422
mRNA Expression by UniProt/SwissProt for ASPH Gene
Q12797-ASPH_HUMAN
Tissue specificity:
Isoform 1 is detected in all tissues tested. Isoform 8 is mainly expressed in pancreas, heart, brain, kidney and liver. Isoform 8 is expressed in kidney (at protein level).
Primer Products
-
OriGene qPCR primer pairs and template standards for ASPH
-
OriGene qPCR primer pairs for ASPH
No data available for mRNA differential expression in normal tissues for ASPH Gene
Orthologs for ASPH Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | ASPH 35 |
|
||
| ASPH 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Asph 35 |
|
||
| Asph 16 |
|
||||
| Asph 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | ASPH 35 |
|
||
| ASPH 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Asph 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ASPH 36 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ASPH 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ASPH 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ASPH 35 |
|
||
| ASPH 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | ASPH 36 |
|
OneToOne | |
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.1434 35 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | ASPH 36 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | Asph 36 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | K09A9.6 36 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.621 36 |
|
OneToOne |
- Species with no ortholog for ASPH:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for ASPH Gene
Variants for ASPH Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs6995412 | - | 61,583,945(+) | CTACC(A/C)TTTTA | reference, missense | |
| VAR_071821 | Facial dysmorphism, lens dislocation, anterior segment abnormalities, and spontaneous filtering blebs (FDLAB) | ||||
| rs2350579 | -- | 61,641,296(+) | TAGTC(C/T)TCAAA | intron-variant | |
| rs2350580 | -- | 61,641,772(+) | TCATA(A/T)TTGAA | intron-variant | |
| rs2350584 | -- | 61,580,601(+) | agatg(A/G)tggca | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv521898 | CNV | Gain | 19592680 |
| esv1949409 | CNV | Deletion | 18987734 |
| esv2737080 | CNV | Deletion | 23290073 |
| esv2737081 | CNV | Deletion | 23290073 |
| esv2662959 | CNV | Deletion | 23128226 |
| esv22699 | CNV | Loss | 19812545 |
| nsv890950 | CNV | Loss | 21882294 |
Residual Variation Intolerance Score:
27.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.99;
49.75% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ASPH Gene
- Human Gene Mutation Database (HGMD)
- ASPH
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ASPH Gene
Disorders for ASPH Gene
(7) MalaCards diseases for ASPH Gene - From: OMIM, ClinVar, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| traboulsi syndrome |
|
|
| regular astigmatism |
|
|
| combat disorder |
|
|
| cholangiocarcinoma |
|
|
| acute stress disorder |
|
|
Search ASPH in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ASPH_HUMAN- Facial dysmorphism, lens dislocation, anterior segment abnormalities, and spontaneous filtering blebs (FDLAB) [MIM:601552]: A syndrome characterized by dislocated crystalline lenses and anterior segment abnormalities in association with a distinctive facies involving flat cheeks and a beaked nose. Some affected individuals develop highly unusual non-traumatic conjunctival cysts (filtering blebs). {ECO:0000269 PubMed:24768550}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for ASPH
No data available for Genatlas for ASPH Gene
Publications for ASPH Gene
- cDNA cloning and characterization of human cardiac junctin. (PMID: 10974562) Lim K.Y. … Kim D.H. (Gene 2000) 2 3 4 23 67
- Cloning and characterization of the human gene encoding aspartyl beta-hydroxylase. (PMID: 7821814) Korioth F. … Frey J. (Gene 1994) 2 3 23
- [Expression of aspartyl-(asparaginyl) beta-hydroxylase in villi in patients with missed abortion]. (PMID: 19197126) Mi C. … Xue M. (Zhong Nan Da Xue Xue Bao Yi Xue Ban 2009) 3 23
- Prognostic value of aspartyl (asparaginyl)-beta-hydroxylase/humbug expression in non-small cell lung carcinoma. (PMID: 19200576) Luu M. … Wang L. (Hum. Pathol. 2009) 3 23
- Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis. (PMID: 19403607) Pritchard T.J. … Kranias E.G. (J. Physiol. (Lond.) 2009) 3 23
Products for ASPH Gene
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- Addgene plasmids for ASPH
- antibodies-online Antibodies for ASPH: See all 81
- antibodies-online Kits for ASPH: See all 9
- antibodies-online Proteins for ASPH: See all 20
- Search antibodies-online for peptides
- GeneTex ASPH antibody for ASPH
- Search GeneTex for Proteins for ASPH
- Search ViGene Biosciences for ASPH
- Search ViGene Biosciences for ASPH
- Santa Cruz Biotechnology (SCBT) Antibodies for ASPH
- Search Santa Cruz Biotechnology (SCBT) for ASPH siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ASPH
- Custom Antibody ServicesProSci Antibodies for ASPH
Sources for ASPH Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon