Aliases for ASNS Gene
External Ids for ASNS Gene
Previous GeneCards Identifiers for ASNS Gene
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]
GeneCards Summary for ASNS Gene
ASNS (Asparagine Synthetase (Glutamine-Hydrolyzing)) is a Protein Coding gene. Diseases associated with ASNS include asparagine synthetase deficiency and congenital microcephaly-severe encephalopathy-progressive cerebral atrophy syndrome. Among its related pathways are Metabolism and Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein. GO annotations related to this gene include protein homodimerization activity and asparagine synthase (glutamine-hydrolyzing) activity.