Aliases for ASIC4 Gene
Aliases for ASIC4 Gene
External Ids for ASIC4 Gene
- HGNC: 21263
- Entrez Gene: 55515
- Ensembl: ENSG00000072182
- OMIM: 606715
- UniProtKB: Q96FT7
Previous HGNC Symbols for ASIC4 Gene
- ACCN4
Previous GeneCards Identifiers for ASIC4 Gene
- GC02P218401
- GC02P219100
- GC02P220378
Summaries for ASIC4 Gene
-
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012]
GeneCards Summary for ASIC4 Gene
ASIC4 (Acid Sensing Ion Channel Subunit Family Member 4) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. GO annotations related to this gene include ion channel activity and sodium ion transmembrane transporter activity. An important paralog of this gene is ASIC1.
UniProtKB/Swiss-Prot for ASIC4 Gene
-
Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.
-
Acid-sensing ion channels (ASIC) are members of the ENaC/Deg (epithelial amiloride-sensitive Na+ channel and degenerin) family of ion channels and are widely expressed in neurons of the central and peripheral nervous system.
No data available for CIViC summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ASIC4 Gene
Genomics for ASIC4 Gene
Regulatory Elements for ASIC4 Gene
Regulatory Element Products
Genomic Location for ASIC4 Gene
- Chromosome:
- 2
- Start:
- 219,514,170 bp from pter
- End:
- 219,538,772 bp from pter
- Size:
- 24,603 bases
- Orientation:
- Plus strand
Genomic View for ASIC4 Gene
- Cytogenetic band:
-
- 2q35 by Ensembl
- 2q35 by Entrez Gene
- 2q35 by HGNC
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ASIC4 Gene
Proteins for ASIC4 Gene
-
Protein details for ASIC4 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96FT7-ASIC4_HUMAN
- Recommended name:
- Acid-sensing ion channel 4
- Protein Accession:
- Q96FT7
- Q53SB7
- Q6GMS1
- Q6PIN9
- Q9NQA4
Protein attributes for ASIC4 Gene
- Size:
- 647 amino acids
- Molecular mass:
- 70105 Da
- Quaternary structure:
-
- Homotrimer or heterotrimer with other ASIC proteins.
- SequenceCaution:
-
- Sequence=CAB93980.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAC51338.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
Protein Expression for ASIC4 Gene
Post-translational modifications for ASIC4 Gene
Other Protein References for ASIC4 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for ASIC4
-
Custom Antibody ServicesOriGene Antibodies for ASIC4
- Novus Biologicals Antibodies for ASIC4
- Invitrogen Antibodies for ASIC4
- antibodies-online Antibodies for ASIC4: See all 48
- GeneTex ASIC4 antibody for ASIC4
-
Santa Cruz Biotechnology (SCBT) Antibodies for ASIC4
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for ASIC4
- Origene Custom Protein Services for ASIC4
- Novus Biologicals lysates for ASIC4
- Search GeneTex for Proteins for ASIC4
Assay Products
- antibodies-online Kits for ASIC4: See all 8
No data available for DME Specific Peptides for ASIC4 Gene
Domains & Families for ASIC4 Gene
Gene Families for ASIC4 Gene
Protein Domains for ASIC4 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ASIC4 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q96FT7UniProtKB/Swiss-Prot:
ASIC4_HUMAN :- Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
- Family:
-
- Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ASIC4 subfamily.
Function for ASIC4 Gene
Molecular function for ASIC4 Gene
- UniProtKB/Swiss-Prot Function:
- Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005216 | ion channel activity | TAS | 10852210 |
| GO:0005272 | sodium channel activity | IEA | -- |
| GO:0015081 | sodium ion transmembrane transporter activity | TAS | 10852210 |
Phenotypes for ASIC4 Gene
- MGI mutant phenotypes for ASIC4:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ASIC4:
Animal Models for ASIC4 Gene
- MGI Knock Outs for ASIC4:
-
- Asic4 tm1b(KOMP)Mbp
Animal Model Products
-
Taconic Biosciences Mouse Models for ASIC4
- Cyagen custom Knockout/knockin (KOKI) mouse models for ASIC4
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ASIC4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ASIC4 gene
- Search ViGene Biosciences for ASIC4
CRISPR Products
-
OriGene CRISPR knockouts for ASIC4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASIC4
- GenScript: Design CRISPR guide RNA sequences for ASIC4
miRNA for ASIC4 Gene
- miRTarBase miRNAs that target ASIC4
-
- hsa-mir-335-5p (MIRT018746)
- hsa-mir-6823-3p (MIRT713967)
- hsa-mir-5006-3p (MIRT713968)
- hsa-mir-4755-5p (MIRT713969)
- hsa-mir-6868-3p (MIRT713970)
- hsa-mir-6881-3p (MIRT713971)
- hsa-mir-6780a-3p (MIRT713972)
- hsa-mir-7111-3p (MIRT713973)
- hsa-mir-211-5p (MIRT713974)
- hsa-mir-204-5p (MIRT713975)
- hsa-mir-623 (MIRT713976)
- hsa-mir-642a-5p (MIRT713977)
- hsa-mir-6845-3p (MIRT713978)
- hsa-mir-4469 (MIRT713979)
- hsa-mir-3667-3p (MIRT713980)
- hsa-mir-6734-3p (MIRT713981)
- hsa-mir-6769b-3p (MIRT713982)
- hsa-mir-4723-3p (MIRT713983)
- hsa-mir-3183 (MIRT713984)
- hsa-mir-5088-3p (MIRT713985)
- hsa-mir-2276-5p (MIRT713986)
- hsa-mir-6892-3p (MIRT713987)
miRNA Products
- Search ViGene Biosciences for ASIC4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ASIC4
- Browse OriGene Inhibitory RNA Products For ASIC4
-
ViGene Biosciences ready-to-package AAV shRNAs for ASIC4 gene
Clone Products
-
OriGene ORF clones in human for ASIC4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ASIC4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASIC4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ASIC4
-
ViGene Biosciences adenoviral particle packaged cDNA for ASIC4 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ASIC4 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ASIC4 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for ASIC4 Gene
Localization for ASIC4 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ASIC4 Gene
- Membrane; Multi-pass membrane protein.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005887 | integral component of plasma membrane | TAS | 10852210 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for ASIC4 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Ion channel transport | ||
| 2 | Development Endothelin-1/EDNRA signaling | ||
| 3 | Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||
Pathways by source for ASIC4 Gene
3 Reactome pathways for ASIC4 Gene
1 KEGG pathway for ASIC4 Gene
Interacting Proteins for ASIC4 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006810 | transport | TAS | 10852210 |
| GO:0006811 | ion transport | IEA | -- |
| GO:0006814 | sodium ion transport | IEA | -- |
| GO:0034220 | ion transmembrane transport | IEA | -- |
| GO:0035725 | sodium ion transmembrane transport | IEA | -- |
No data available for SIGNOR curated interactions for ASIC4 Gene
Drugs & Compounds for ASIC4 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| APETx2 | Pharma | Channel blocker | ASIC3 channel blocker | 0 | ||
| P-552 | Pharma | 0 | ||||
| GMQ hydrochloride | Pharma | Selective ASIC3 opener | 0 | |||
| Neuropeptide SF (mouse, rat) | Pharma | NPFF1 and NPFF2 agonist | 0 | |||
| Psalmotoxin 1 | Pharma | Channel blocker | acid-sensing ion channel 1a (ASIC1a) blocker, Potent and selective ASIC1a channel blocker | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs | |
|---|---|---|---|---|---|---|
| sodium |
|
7440-23-5 |
|
|||
| Mambalgin 1 |
|
1609937-15-6 |
|
|
(5) Tocris Compounds for ASIC4 Gene
| Compound | Action | Cas Number |
|---|---|---|
| APETx2 | ASIC3 channel blocker | 713544-47-9 |
| GMQ hydrochloride | Selective ASIC3 opener | 5361-15-9 |
| Mambalgin 1 | Selective ASIC1a inhibitor; analgesic | 1609937-15-6 |
| Neuropeptide SF (mouse, rat) | NPFF1 and NPFF2 agonist | 230960-31-3 |
| Psalmotoxin 1 | Potent and selective ASIC1a channel blocker |
(1) ApexBio Compounds for ASIC4 Gene
| Compound | Action | Cas Number |
|---|---|---|
| APETx2 | 713544-47-9 |
Drug Products
- ApexBio compounds for ASIC4
Transcripts for ASIC4 Gene
mRNA/cDNA for ASIC4 Gene
- (4) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (25) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ASIC4 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ASIC4
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASIC4
- GenScript: Design CRISPR guide RNA sequences for ASIC4
miRNA Products
- Search ViGene Biosciences for ASIC4
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ASIC4
- Browse OriGene Inhibitory RNA Products For ASIC4
-
ViGene Biosciences ready-to-package AAV shRNAs for ASIC4 gene
Clone Products
-
OriGene ORF clones in human for ASIC4
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ASIC4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASIC4
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||
| SP4: | - |
Expression for ASIC4 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
-
Ovary (Reproductive System)
- Granulosa Cells Primary Follicle
mRNA differential expression in normal tissues according to GTEx for ASIC4 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ASIC4 Gene
NURSA nuclear receptor signaling pathways regulating expression of ASIC4 Gene:
ASIC4SOURCE GeneReport for Unigene cluster for ASIC4 Gene:
Hs.87469mRNA Expression by UniProt/SwissProt for ASIC4 Gene:
Q96FT7-ASIC4_HUMANEvidence on tissue expression from TISSUES for ASIC4 Gene
- Nervous system(4.6)
Primer Products
-
OriGene qPCR primer pairs for ASIC4
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for ASIC4 Gene
Orthologs for ASIC4 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ACCN4 34 |
|
||
| ASIC4 35 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | ASIC4 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ASIC4 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Asic4 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Asic4 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ASIC4 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ASIC4 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ASIC4 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | ASIC4 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | asic4 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | asic4a 34 35 |
|
||
| asic4b 35 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | unc-105 36 |
|
|
|
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany | |
| -- 35 |
|
ManyToMany |
- Species where no ortholog for ASIC4 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ASIC4 Gene
Variants for ASIC4 Gene
| SNP ID | Clin | Chr 02 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000076930 | -- | 219,519,223(+) | GTTGT(A/G)AGGAT | intron-variant | |
| rs1000338083 | -- | 219,531,348(+) | GCAAC(A/T)GAGCA | intron-variant | |
| rs1000365468 | -- | 219,524,771(+) | GGTTT(C/T)GCTGT | intron-variant | |
| rs1000366696 | -- | 219,521,066(+) | CCACA(C/G)CAGCT | intron-variant | |
| rs1000439878 | -- | 219,515,879(+) | ACATG(C/T)CTGCC | intron-variant, upstream-variant-2KB |
Relevant External Links for ASIC4 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ASIC4 Gene
Disorders for ASIC4 Gene
Relevant External Links for ASIC4
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ASIC4
No disorders were found for ASIC4 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ASIC4 Gene
Publications for ASIC4 Gene
- A new member of acid-sensing ion channels from pituitary gland. (PMID: 10852210) Gruender S. … Ruppersberg J.P. (NeuroReport 2000) 2 3 4 64
- Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Acid-sensing ion channel (ASIC) 4 gene: physical mapping, genomic organisation, and evaluation as a candidate for paroxysmal dystonia. (PMID: 11571555) Gruender S. … Fink J.K. (Eur. J. Hum. Genet. 2001) 3 4 64
- Acid-sensing ion channel (ASIC) 4 predominantly localizes to an early endosome-related organelle upon heterologous expression. (PMID: 26667795) Schwartz V. … GrA1nder S. (Sci Rep 2015) 3 64
Products for ASIC4 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for ASIC4
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for ASIC4
- Origene Custom Protein Services for ASIC4
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ASIC4
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- OriGene qPCR primer pairs for ASIC4
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for ASIC4 in any vector
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- GenScript: Design CRISPR guide RNA sequences for ASIC4
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
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- Browse Sino Biological cDNA Clones
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- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ASIC4
- Novus Biologicals lysates for ASIC4
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Taconic Biosciences Mouse Models for ASIC4
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for ASIC4
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- ApexBio compounds for ASIC4
- antibodies-online Antibodies for ASIC4: See all 48
- antibodies-online Kits for ASIC4: See all 8
- Search antibodies-online for proteins
- Search antibodies-online for peptides
- GeneTex ASIC4 antibody for ASIC4
- Search GeneTex for Proteins for ASIC4
- ViGene Biosciences adenoviral particle packaged cDNA for ASIC4 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ASIC4 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ASIC4 gene
- Search ViGene Biosciences for ASIC4
- Santa Cruz Biotechnology (SCBT) Antibodies for ASIC4
- Search Santa Cruz Biotechnology (SCBT) for ASIC4 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ASIC4
- Horizon Cell Lines for ASIC4
- Cyagen custom Knockout/knockin (KOKI) mouse models for ASIC4
- VectorBuilder custom plasmid, inducible vectors for ASIC4
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASIC4
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ASIC4 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
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- (153) dbSUPER
- (154) TISSUES
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