Aliases for ASH2L Gene
External Ids for ASH2L Gene
Previous HGNC Symbols for ASH2L Gene
Previous GeneCards Identifiers for ASH2L Gene
GeneCards Summary for ASH2L Gene
ASH2L (Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila)) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Chromatin organization. GO annotations related to this gene include transcription regulatory region DNA binding and histone methyltransferase activity (H3-K4 specific).
UniProtKB/Swiss-Prot for ASH2L Gene
Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates Lys-4 of histone H3, but not if the neighboring Lys-9 residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at Lys-4 of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.