Aliases for ASH1L Gene
External Ids for ASH1L Gene
Previous GeneCards Identifiers for ASH1L Gene
This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions. [provided by RefSeq, Jul 2008]
GeneCards Summary for ASH1L Gene
ASH1L (ASH1 Like Histone Lysine Methyltransferase) is a Protein Coding gene. Diseases associated with ASH1L include Intellectual Disability And/Or Autism Spectrum Disorder, Ash1l-Related. Among its related pathways are Chromatin organization and Lysine degradation. GO annotations related to this gene include chromatin binding and histone methyltransferase activity (H3-K4 specific). An important paralog of this gene is SETD2.
UniProtKB/Swiss-Prot for ASH1L Gene
Histone methyltransferase specifically methylating Lys-36 of histone H3 (H3K36me).