ASGR2 Gene
protein-coding GIFtS: 53
GCID: GC17M007004
|
|
asialoglycoprotein receptor 2
| |
Aliases
for ASGR2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Asialoglycoprotein Receptor 21 2 | | ASGPR22 | | CLEC4H21 2 3 | | HBXBP2 | | Hepatic Lectin H22 3 | | HBxAg-Binding Protein2 | | HL-22 3 | | ASGP-R 23 | | C-Type Lectin Domain Family 4 Member H22 3 | | ASGPR 23 | | ASGP-R22 | | |
Export aliases for ASGR2 gene to outside databasesPrevious GC identifers: GC17M007393 GC17M007735 GC17M006949 GC17M007205 GC17M006945 GC17M006898 |
Summaries
for ASGR2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ASGR2:
This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays acritical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation ofglycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor mayfacilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drugdelivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, whichare encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternativelyspliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Jan2011)
UniProtKB/Swiss-Prot: ASGR2_HUMAN, P07307Function: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complexcarbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units.After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle,where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface
|
Genomic Views
for ASGR2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010718.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ASGR2 gene promoter:
COUP-TF1 COUP-TF COUP Nkx2-5 HNF-4alpha1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ASGR2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASGR2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17p Ensembl cytogenetic band: 17p13.1 HGNC cytogenetic band: 17pASGR2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M007004: view genomic region
(about GC identifiers)
Start:
|
7,004,641 bp from pter |
End:
|
7,019,019 bp from pter |
Size:
|
14,379 bases |
Orientation:
|
minus strand |
|
Proteins
for ASGR2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ASGR2_HUMAN, P07307 (See
protein sequence)Recommended Name: Asialoglycoprotein receptor 2 Size: 311 amino acids; 35092 Da
Subunit: The functioning ligand-binding unit of this receptor is thought to be at least a dimer. Interacts with LASS2
Subcellular location: Membrane; Single-pass type II membrane protein
Miscellaneous: Calcium is required for ligand binding
Secondary accessions: A6NLV8 A8MT12 D3DTM9 D3DTN0 O00448 Q03969Alternative splicing: 3 isoforms: P07307-1 P07307-2 P07307-3 Explore the universe of human proteins at neXtProt for ASGR2: NX_P07307
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P07307
ASGR2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001172.1 NP_001188281.1 NP_550434.1 NP_550435.1 NP_550436.1
ENSEMBL proteins: ENSP00000347140 ENSP00000254850 ENSP00000458972 ENSP00000405844 ENSP00000458835 ENSP00000370339
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
ASGR2 for ontologies About GeneDecksing
ASGR2 Antibody Products:
Assay Products for ASGR2: |
Protein
Domains /
Families
for ASGR2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ASGR2 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P07307ProtoNet protein and cluster: P07307 2 Blocks protein families: IPB002353 Type II antifreeze protein signature IPB005640 Hepatic lectin
UniProtKB/Swiss-Prot: ASGR2_HUMAN, P07307Similarity: Contains 1 C-type lectin domain |
Function
for ASGR2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ASGR2_HUMAN, P07307Function: Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complexcarbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units.After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle,where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ASGR2 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ASGR2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): ASGR2 (NM_001181) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ASGR2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASGR2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASGR2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ASGR2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ASGR2:
Animal Models:
Mouse knock-out Asgr2tm1Her for ASGR2
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Asgr2):
ASGR2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ASGR2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ASGR2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/10 Interacting proteins for ASGR2 (P073071, 3 ENSP000003471404) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
ASGR2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ASGR2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ASGR2 for compounds About GeneDecksing
 Browse Tocris compounds for ASGR2
1 HMDB Compound for ASGR2 About this table
1 DrugBank Compound for ASGR2 About this table
10/12 Novoseek chemical compound relationships for ASGR2 gene (see all 12) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| pvla |
87.3 |
9 |
11444822 (3), 14586135 (1), 16004427 (1), 16158256 (1) |
| galactose |
69.8 |
21 |
18855599 (2), 9555658 (2), 15885467 (2), 17931643 (1) (see all 15) |
| sialic acid |
42.4 |
2 |
17103087 (1), 9989767 (1) |
| spec-t |
36.9 |
1 |
14575385 (1) |
| glycolipid |
23.5 |
2 |
16254203 (1), 15509179 (1) |
| doxorubicin |
17.1 |
4 |
15189276 (1), 11489324 (1), 20403430 (1) |
| lysine |
6.87 |
2 |
7873664 (1), 7948096 (1) |
| ethanol |
5.89 |
5 |
18336663 (3), 14986823 (1), 18161881 (1) |
| calcium |
0 |
3 |
12477859 (1), 7844558 (1) |
| fatty acid |
0 |
1 |
8668674 (1) |
Search CenterWatch for drugs/clinical trials and news about ASGR2
|
Transcripts
for ASGR2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ASGR2 gene (5 alternative transcripts): NM_001181.4 NM_001201352.1 NM_080912.3 NM_080913.3 NM_080914.2 Unigene Cluster for ASGR2: Asialoglycoprotein receptor 2 Hs.654440 [show with all ESTs]Unigene Representative Sequence: NM_0809128 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000355035(uc002gen.1) ENST00000254850(uc002geq.3) ENST00000574106
ENST00000446679 ENST00000576487(uc010clw.2) ENST00000450034(uc010vtl.1)
ENST00000574868 ENST00000380952(uc002gep.3 uc002geo.2 uc002ger.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ASGR2 (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ASGR2 (see all 4)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): ASGR2 (NM_001181) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ASGR2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASGR2 |
Additional cDNA sequence: AF529374.1 AK310123.1 BC017251.2 M11025.1 U97197.1 X55283.1 X55284.1 4 DOTS entries: DT.91677142 DT.92324210 DT.100755545 DT.95259760 24/65 AceView cDNA sequences (see all 65): BQ647289 AF529374 AI635553 BQ648893 NM_080913 BQ651695 BC017251 CR594935 BU506758 AL532507 CB111973 AW950089 BM928635 X55284 T27873 BV194484 BM561839 BQ653259 U97197 BI252350 AL564408 BX283340 BX483468 M11025
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ASGR2 About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b |
|---|
|
| SP1: | | | | | | | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ASGR2
|
Expression
for ASGR2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ASGR2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTCTGCTTCA
About this image
See ASGR2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ASGR2
SOURCE GeneReport for Unigene cluster: Hs.654440
UniProtKB/Swiss-Prot: ASGR2_HUMAN, P07307Tissue specificity: Expressed exclusively in hepatic parenchymal cells
SABiosciences Custom PCR Arrays for ASGR2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ASGR2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ASGR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASGR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASGR2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASGR2 |
Orthologs
for ASGR2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ASGR2 gene from 2/9 species (see all 9) About this table
ENSEMBL Gene Tree for ASGR2 (if available)
TreeFam Gene Tree for ASGR2 (if available) |
Paralogs
for ASGR2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ASGR2 gene
- CD2072 CLEC4E2 CLEC4M2 CLEC4F2 CD2092 CLEC10A2 FCER22 CLEC4A2
- ASGR12 CLEC6A2 CLEC4C2 CLEC4D2 CLEC4G2
9 SIMAP similar genes for ASGR2 using alignment to 3 protein entries: ASGR2_HUMAN (see all proteins):HBXBP ASGR1 FCER2 CLEC10A CLEC6A CLEC4E
REG1A CLEC4D REG4
ASGR2 for paralogs About GeneDecksing
|
Genomic Variants
for ASGR2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ASGR2 (7004641 - 7019019 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ASGR2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ASGR2 |
|
Disorders
/ Diseases
for ASGR2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ASGR2 for disorders About GeneDecksing
OMIM gene information: 108361
OMIM disorders: --
17  diseases for ASGR2: About MalaCardshepatitis hepatitis b liver cirrhosis alcoholic liver cirrhosis
hepatitis c liver disease urethritis hepatocellular carcinoma
autoimmune hepatitis jaundice nephropathy alcoholism
influenza carcinoma leukemia cholesterol
immunodeficiency
2 diseases from the University of Copenhagen DISEASES database for ASGR2:Autoimmune hepatitis Hepatitis 10/21 Novoseek disease relationships for ASGR2 gene (see all 21) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hepatitis autoimmune |
61.6 |
6 |
19576873 (2), 8590155 (1), 15890353 (1), 7508490 (1) (see all 5) |
| hepatitis chronic active |
57 |
3 |
1979365 (1), 1532926 (1), 12002624 (1) |
| hepatitis chronic |
53.8 |
2 |
7508490 (1), 1955777 (1) |
| other liver diseases |
51.8 |
1 |
16396634 (1) |
| liver diseases |
42 |
5 |
1532926 (2), 15890353 (1), 1955777 (1), 8301043 (1) |
| hepatocellular carcinoma |
41.9 |
7 |
10075085 (2), 16396634 (1), 10507763 (1), 20403430 (1) (see all 6) |
| liver damage |
41.8 |
1 |
16920400 (1) |
| liver mass |
40 |
1 |
9935069 (1) |
| autoimmune response |
34.6 |
1 |
1955777 (1) |
| liver cirrhosis |
29.5 |
1 |
12297928 (1) |
Human Genome Epidemiology (HuGE) Navigator: ASGR2 (1 document)
Export disorders for ASGR2 gene to outside databases
|
Publications
for ASGR2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ASGR2 gene, integrated from 9 sources (see all 145):
(articles sorted by number of sources associating them with ASGR2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Sequence of a second human asialoglycoprotein receptor: conservation of two receptor genes during evolution. (PubMed id 3863106)1, 2, 3 Spiess M. and Lodish H.F. (1985)
- The B domain of coagulation factor VIII interacts with the asialoglycoprotein receptor. (PubMed id 15946216)1, 7 Bovenschen N....Mertens K. (2005)
- Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. (PubMed id 16335952)1, 2 Liu T.... Smith R.D. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1. (PubMed id 11543633)1, 2 Pan H....Gu J.-R. (2001)
- Differences in the abundance of variably spliced transcripts for the second asialoglycoprotein receptor polypeptide, H2, in normal and transformed human liver. (PubMed id 1371982)1, 2 Paietta E.... Racevskis J. (1992)
- Targeted delivery of macromolecular drugs: asialoglycoprotein receptor (ASGPR) expression by selected hepatoma cell lines used in antiviral drug development. (PubMed id 18855599)1, 9 Li Y....Wiebe L.I. (2008)
- Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes. (PubMed id 12477859)1, 9 Saunier B....Kohn L.D. (2003)
- Autoantibodies to asialoglycoprotein receptor (ASGPR) measured by a novel ELISA--revival of a disease-activity marker in autoimmune hepatitis. (PubMed id 19576873)1, 9 Hausdorf G....Klein R. (2009)
- H2, the minor subunit of the human asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid. (PubMed id 12089159)1, 9 Saxena A....Weigel P.H. (2002)
|
External Searches for ASGR2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ASGR2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ASGR2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ASGR2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ASGR2 | Pharmacogenomics, SNPs, Pathways | | Functional Glycomics Gateway - Glycan Binding | http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_216 |
|
| | |
About This Section
| Patent Information for ASGR2 gene:
Search GeneIP for patents involving ASGR2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ASGR2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | OriGene Antibodies for ASGR2 | | OriGene shRNA RFP for ASGR2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ASGR2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ASGR2 | | | OriGene Protein Over-expression Lysate for ASGR2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ASGR2 | | OriGene 3'-UTR Clone for ASGR2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ASGR2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ASGR2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ASGR2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ASGR2 | | OriGene Custom Protein Services for ASGR2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ASGR2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ASGR2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASGR2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASGR2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASGR2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASGR2 |
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| | | | Search Tocris compounds for ASGR2 |
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 | | | ASGR2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASGR2 |
|  |  |  | | | | ThermoFisher Antibodies for ASGR2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASGR2 |
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