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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ASF1B Gene

protein-coding   GIFtS: 54
GCID: GC19M014230

ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
 Explore 3 diseases affiliated with
ASF1B via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ASF1B    

Aliases
for ASF1B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
ASF1 Anti-Silencing Function 1 Homolog B (S. Cerevisiae)1 2     HAsf1b1
Anti-Silencing Function Protein 1 Homolog B2 3     HCIA-II1
CIA-II2 3     FLJ106041
CCG1-Interacting Factor A-II2 3     Histone Chaperone ASF1B2
HAsf11     

External Ids:    HGNC: 209961   Entrez Gene: 557232   Ensembl: ENSG000001050117   OMIM: 6091905   UniProtKB: Q9NVP23   

Export aliases for ASF1B gene to outside databases

Previous GC identifers: GC19M014597 GC19M014075 GC19M014091 GC19M013801


Summaries
for ASF1B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ASF1B:
This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing
function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell
cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring a
constant supply of histones at sites of nucleosome assembly. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2
Function: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome
assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent
chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A
and HIRA. Required for spermatogenesis

Gene Wiki entry for ASF1B


Genomic Views
for ASF1B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011295.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ASF1B gene promoter:
         HOXA9   HOXA9B   TBP   GATA-3   STAT1beta   Nkx2-5   STAT1alpha   Meis-1b   CP2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ASF1B promoter sequence
   Search SABiosciences Chromatin IP Primers for ASF1B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASF1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.12   Ensembl cytogenetic band:  19p13.12   HGNC cytogenetic band: 19p13.12

ASF1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASF1B gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M014230:  view genomic region     (about GC identifiers)

Start:
 14,230,321 bp from pter      End:
 14,247,768 bp from pter
Size:
 17,448 bases      Orientation:
 minus strand

Proteins
for ASF1B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2 (See protein sequence)
Recommended Name: Histone chaperone ASF1B  
Size: 202 amino acids; 22434 Da
Subunit: Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the CHAF1A,
CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with HAT1, NASP, TAF1, TLK1 and TLK2. Interacts with CDAN1.
Found in a cytosolic complex with CDAN1, ASF1A, IPO4 and histones H3.1 and H4
Subcellular location: Nucleus
Secondary accessions: Q53G51 Q9NVZ0

Explore the universe of human proteins at neXtProt for ASF1B: NX_Q9NVP2

Post-translational modifications:

  • Phosphorylated by TLK1 and TLK21
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9NVP2

    • ASF1B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060624.1  
    ENSEMBL proteins: 
     ENSP00000263382   ENSP00000468513   ENSP00000464802   ENSP00000466409   ENSP00000466257  

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    ProSpec Recombinant Protein for ASF1B
    Uscn Proteins for ASF1B

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000785chromatin IEA--
    GO:0005634nucleus IEA--


    ASF1B for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for ASF1B gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ASF1B for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR006818 Histone_chaperone_ASF1-like

    Graphical View of Domain Structure for InterPro Entry Q9NVP2

    ProtoNet protein and cluster: Q9NVP2

    UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2
    Similarity: Belongs to the ASF1 family


    Function
    for ASF1B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2
    Function: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome
    assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent
    chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A
    and HIRA. Required for spermatogenesis

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ASF1B
    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate ASF1B (see all 22):
    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-3616-5p hsa-miR-302e hsa-miR-520a-3p hsa-miR-372 hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmid: ASF1B 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: ASF1B
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for ASF1B

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0042393histone binding IEA--


    ASF1B for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Asf1b):
     no phenotypic analysis 

    ASF1B for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ASF1B gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Chromatin Regulation / Acetylation
    		Chromatin Regulation / Acetylation1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ASF1B
        Chromatin Regulation / Acetylation



    ASF1B for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ASF1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/133 Interacting proteins for ASF1B (Q9NVP22, 3 ENSP000002633824) via UniProtKB, MINT, STRING, and/or I2D (see all 133)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST4H4P628052, 3, ENSP000003507674MINT-7220359 I2D: score=2 STRING: ENSP00000350767
    HIST1H4BP628052, 3MINT-7220359 I2D: score=2 
    HIST1H4CP628052, 3MINT-7220359 I2D: score=2 
    HIST1H4DP628052, 3MINT-7220359 I2D: score=2 
    HIST1H4EP628052, 3MINT-7220359 I2D: score=2 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006334nucleosome assembly IEA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0007283spermatogenesis IEA--


    ASF1B for ontologies           About GeneDecksing



    Drugs & Compounds
    for ASF1B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ASF1B
    Search CenterWatch for drugs/clinical trials and news about ASF1B 

    Transcripts
    for ASF1B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ASF1B gene: 
    NM_018154.2  

    Unigene Cluster for ASF1B:

    ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
    Hs.26516  [show with all ESTs]
    Unigene Representative Sequence: BM909565
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263382(uc002mye.3) ENST00000592798 ENST00000590835 ENST00000589468
    ENST00000474890

    miRNA
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    8/22 QIAGEN miScript miRNA Assays for microRNAs that regulate ASF1B (see all 22):
    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-3616-5p hsa-miR-302e hsa-miR-520a-3p hsa-miR-372 hsa-miR-548x
    SwitchGear 3'UTR luciferase reporter plasmid: ASF1B 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: ASF1B
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASF1B
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASF1B

    Additional cDNA sequence: 

    AB104486.1 AF279307.1 AK001288.1 AK001466.1 AK223080.1 AK302134.1 BC007726.2 BC010014.2 
    BC036521.1 CR457235.1 

    10 DOTS entries:

    DT.100650546  DT.213214  DT.100728360  DT.95154114  DT.95154117  DT.121504465  DT.92450407  DT.97847971 
    DT.121504505  DT.95154112 

    24/342 AceView cDNA sequences (see all 342):

    CR608925 BE842656 CR601959 BI769943 BE260205 CR609105 BE885931 BU930942 
    BQ069922 BM842506 BF064047 CR621931 BI829260 BX462275 BG757167 BU167714 
    BM761657 BQ877375 BM542679 BF062913 AI992041 CB121201 BX417063 AI635792 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ASF1B    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d
    SP1:                                                  -                           
    SP2:                                      -           -                           
    SP3:                                -                 -                           
    SP4:                                                                              
    SP5:                                      -     -     -                           


    ECgene alternative splicing isoforms for ASF1B

    Expression
    for ASF1B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ASF1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGGATGCTGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ASF1B expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    LiverLiver LobuleLiver
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ progenitor F15 (Embryonic Progenitor Cell)

    See ASF1B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ASF1B

    SOURCE GeneReport for Unigene cluster: Hs.26516

    UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2
    Tissue specificity: Highly expressed in testis and at lower levels in colon, small intestine and thymus

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    In Situ
    Assay Products:     
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    Orthologs
    for ASF1B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ASF1B gene from 8/30 species (see all 30)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Asf1b1 , 5 ASF1 anti-silencing function 1 homolog B (S. cerevisiae) less1, 5 87.62(n)1
    91.58(a)1    		   8 (40.22 cM)5
    669291  NM_024184.21  NP_077146.11 
     839555075 
    lizard
    (Anolis carolinensis)    		 Reptilia ASF1B6
    		 --
    		 75(a)
    		 1 ↔ 1
    		 2(119356731-119364753)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.45262 Transcribed sequence with moderate similarity to protein refNP_060624.1 (H.sapiens) hypothetical protein FLJ10604 [Homo sapiens] less 76.4(n)    AL877193.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufb20g032 Transcribed sequence with moderate similarity to protein refNP_060624.1 (H.sapiens) hypothetical protein FLJ10604 [Homo sapiens] less 76.94(n)    CF996135.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta asf16
    		 anti-silencing factor 1
    		 51(a)
    		 1 → many
    		 3L(19611994-19613498)
    worm
    (Caenorhabditis elegans)    		 Secernentea asfl-16
    unc-856
    		 Probable histone chaperone asf-1
    		 33(a)
    31(a)
    		 many ↔ many
    many ↔ many
    		 I(9658265-9660064)
    II(4702066-4703261)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AtSP76
    ASF1B6
    		 histone chaperone ASF1B
    		 49(a)
    44(a)
    		 many ↔ many
    many ↔ many
    		 1(24892340-24893766)
    5(15208470-15210215)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 anti-silencing protein, ASF1-like domain containin...
    anti-silencing protein, ASF1-like domain containin...
    		 51(a)
    27(a)
    		 many ↔ many
    many ↔ many
    		 5(27471637-27476843)
    1(28241102-28245215)


    ENSEMBL Gene Tree for ASF1B (if available)
    TreeFam Gene Tree for ASF1B (if available) 

    Paralogs
    for ASF1B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ASF1B gene
    ASF1A2  
    1 SIMAP similar gene for ASF1B using alignment to 5 protein entries:     ASF1B_HUMAN (see all proteins):
    ASF1A

    ASF1B for paralogs           About GeneDecksing



    Genomic Variants
    for ASF1B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/302 NCBI SNPs in ASF1B are shown (see all 302)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 19 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs342510801,2
    		C--13804747(+) TGGAC-/TTTTTT 1 -- int12Minor allele frequency- T:0.25NA CSA 4
    rs621221331,2
    		F--13819624(+) CCGCTC/TTCGCC 1 -- int12Minor allele frequency- T:0.50NA 6
    rs1502416041,2
    		--14230756(+) AAGAAA/TCTTCC 1 -- ut310--------
    rs762871601,2
    		--14230802(+) ACTAAC/GTAACA 1 -- ut312Minor allele frequency- G:0.06CSA WA 120
    rs1388743021,2
    		--14230855(+) ATGTAC/TAGGAA 1 -- ut310--------
    rs1864101541,2
    		--14230970(+) GATCAA/GTGGTA 1 -- ut310--------
    rs1494845501,2
    		--14231071(+) TCTTAC/TAGGCC 1 -- ut310--------
    rs1459566831,2
    		--14231203(+) ATGGGC/TCCTGC 1 -- ut310--------
    rs1995254411,2
    		--14231240(+) CCTCCC/TGGCGT 1 -- ut310--------
    rs37454641,2
    		C,F,A,H,--14231243(-) AGCACG/ACCGGG 1 -- ut31 ese313Minor allele frequency- A:0.16NA WA CSA EA EU 562

    HapMap Linkage Disequilibrium report for ASF1B (14230321 - 14247768 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for ASF1B
         3 CNVs: 50073 73315 5089

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    Disorders / Diseases
    for ASF1B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ASF1B for disorders           About GeneDecksing

    OMIM gene information: 609190    OMIM disorders: --

    3 diseases for ASF1B:    About MalaCards
    chickenpox    breast cancer    malaria

    Human Genome Epidemiology (HuGE) Navigator: ASF1B (3 documents)

    Export disorders for ASF1B gene to outside databases

    Publications
    for ASF1B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ASF1B gene, integrated from 9 sources (see all 41):
    (articles sorted by number of sources associating them with ASF1B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. (PubMed id 11897662)1, 2, 3 Mello J.A....Almouzni G. (2002)
    2. Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases. (PubMed id 11470414)1, 2, 3 Sillje H.H. and Nigg E.A. (2001)
    3. Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis. (PubMed id 12842904)1, 2, 9 Umehara T. and Horikoshi M. (2003)
    4. Codanin-1, mutated in the anaemic disease CDAI, regula tes Asf1 function in S-phase histone supply. (PubMed id 22407294)1, 2 Ask K....Groth A. (2012)
    5. Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases. (PubMed id 20016786)1, 2 Pilyugin M....Moshkin Y.M. (2009)
    6. Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly. (PubMed id 16980972)1, 2 Tang Y.... Marmorstein R. (2006)
    7. Human Asf1 regulates the flow of S phase histones during replicational stress. (PubMed id 15664198)1, 2 Groth A....Almouzni G. (2005)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    9. Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. (PubMed id 14718166)1, 2 Tagami H.... Nakatani Y. (2004)
    10. Transcriptional regulation of human chromatin assembly factor ASF1. (PubMed id 17328667)1, 9 Hayashi R....Yoshida K. (2007)

    External Searches for ASF1B gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ASF1B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55723 HGNC: 20996 AceView: ASF1B Ensembl:ENSG00000105011 euGenes: HUgn55723
    ECgene: ASF1B H-InvDB: ASF1B

    Other Databases showing ASF1B gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ASF1B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ASF1B Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ASF1B gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ASF1B gene:
    Search GeneIP for patents involving ASF1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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