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ASF1B Gene

protein-coding   GIFtS: 58
GCID: GC19M014230

Anti-Silencing Function 1B Histone Chaperone

(Previous name: ASF1 anti-silencing function 1 homolog B (S. cerevisiae))
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Anti-Silencing Function 1B Histone Chaperone1 2     hAsf1b2 3
Anti-Silencing Function Protein 1 Homolog B2 3     hCIA-II2 3
CIA-II2 3     ASF1 Anti-Silencing Function 1 Homolog B (S. Cerevisiae)1
CCG1-Interacting Factor A-II2 3     ASF1 Anti-Silencing Function 1 Homolog B2
hAsf12 3     Histone Chaperone ASF1B2

External Ids:    HGNC: 209961   Entrez Gene: 557232   Ensembl: ENSG000001050117   OMIM: 6091905   UniProtKB: Q9NVP23   

Export aliases for ASF1B gene to outside databases

Previous GC identifers: GC19M014597 GC19M014075 GC19M014091 GC19M013801


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ASF1B Gene:
This gene encodes a member of the H3/H4 family of histone chaperone proteins and is similar to the anti-silencing
function-1 gene in yeast. The encoded protein is the substrate of the tousled-like kinase family of cell
cycle-regulated kinases, and may play a key role in modulating the nucleosome structure of chromatin by ensuring
a constant supply of histones at sites of nucleosome assembly. (provided by RefSeq, Jul 2008)

GeneCards Summary for ASF1B Gene:
ASF1B (anti-silencing function 1B histone chaperone) is a protein-coding gene. GO annotations related to this gene include histone binding. An important paralog of this gene is ASF1A.

UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2
Function: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome
assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent
chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by
ASF1A and HIRA. Required for spermatogenesis

Gene Wiki entry for ASF1B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the ASF1B gene promoter:
         HOXA9   HOXA9B   TBP   GATA-3   STAT1beta   Nkx2-5   STAT1alpha   Meis-1b   CP2   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidASF1B promoter sequence
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Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ASF1B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.12   Ensembl cytogenetic band:  19p13.12   HGNC cytogenetic band: 19p13.12

ASF1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASF1B gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M014230:  view genomic region     (about GC identifiers)

Start:
14,230,321 bp from pter      End:
14,247,768 bp from pter
Size:
17,448 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2 (See protein sequence)
Recommended Name: Histone chaperone ASF1B  
Size: 202 amino acids; 22434 Da
Subunit: Interacts with histone H3 (including both histone H3.1 and H3.3) and histone H4. Interacts with the
CHAF1A, CHAF1B and RBBP4 subunits of the CAF-1 complex. Interacts with HAT1, NASP, TAF1, TLK1 and TLK2. Interacts
with CDAN1. Found in a cytosolic complex with CDAN1, ASF1A, IPO4 and histones H3.1 and H4
Secondary accessions: Q53G51 Q9NVZ0

Explore the universe of human proteins at neXtProt for ASF1B: NX_Q9NVP2

Explore proteomics data for ASF1B at MOPED

Post-translational modifications: 

  • Phosphorylated by TLK1 and TLK21
  • Ubiquitination2 at Lys3, Lys129
  • Modification sites at PhosphoSitePlus

  • See ASF1B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060624.1  
    ENSEMBL proteins: 
     ENSP00000263382   ENSP00000468513   ENSP00000464802   ENSP00000466409   ENSP00000466257  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR006818 Histone_chaperone_ASF1-like

    Graphical View of Domain Structure for InterPro Entry Q9NVP2

    ProtoNet protein and cluster: Q9NVP2

    UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2
    Similarity: Belongs to the ASF1 family


    Find genes that share domains with ASF1B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASF1B_HUMAN, Q9NVP2
    Function: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome
    assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent
    chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by
    ASF1A and HIRA. Required for spermatogenesis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0042393histone binding IEA--
         
    Find genes that share ontologies with ASF1B           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Asf1b):
     no phenotypic analysis 

    Find genes that share phenotypes with ASF1B           About GenesLikeMe

    Animal Models:
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ASF1B_HUMAN, Q9NVP2: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    extracellular2
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000785chromatin IEA--
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with ASF1B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ASF1B About    
    See pathways by source

    SuperPathContained pathways About
    1Chromatin Regulation / Acetylation
    Chromatin Regulation / Acetylation


    Find genes that share SuperPaths with ASF1B           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ASF1B
        Chromatin Regulation / Acetylation



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ASF1B
    Interactions:

        GeneGlobe Interaction Network for ASF1B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ASF1B (Q9NVP22, 3 ENSP000002633824) via UniProtKB, MINT, STRING, and/or I2D (see all 411)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628052, 3, ENSP000003529804MINT-7220359 I2D: score=2 STRING: ENSP00000352980
    HIST1H4HP628052, 3, ENSP000002893524MINT-7220359 I2D: score=2 STRING: ENSP00000289352
    HIST4H4P628052, 3, ENSP000003507674MINT-7220359 I2D: score=2 STRING: ENSP00000350767
    HIST1H4BP628052, 3MINT-7220359 I2D: score=2 
    HIST1H4CP628052, 3MINT-7220359 I2D: score=2 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006333chromatin assembly or disassembly ----
    GO:0006334nucleosome assembly IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0007275multicellular organismal development IEA--

    Find genes that share ontologies with ASF1B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Tocris compounds for ASF1B



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ASF1B gene: 
    NM_018154.2  

    Unigene Cluster for ASF1B:

    ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
    Hs.26516  [show with all ESTs]
    Unigene Representative Sequence: BM909565
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263382(uc002mye.3) ENST00000592798 ENST00000590835 ENST00000589468
    ENST00000474890
    miRNA
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    hsa-miR-302d hsa-miR-520e hsa-miR-520f hsa-miR-3616-5p hsa-miR-302e hsa-miR-520a-3p hsa-miR-372 hsa-miR-548x
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    Additional mRNA sequence: 

    AB104486.1 AF279307.1 AK001288.1 AK001466.1 AK223080.1 AK302134.1 BC007726.2 BC010014.2 
    BC036521.1 CR457235.1 

    10 DOTS entries:

    DT.100650546  DT.213214  DT.100728360  DT.95154114  DT.95154117  DT.121504465  DT.92450407  DT.97847971 
    DT.121504505  DT.95154112 

    Selected AceView cDNA sequences (see all 342):

    BE731187 CR622368 BM833698 BE327544 AI635792 AW245451 BM743065 BQ232943 
    CR594548 CR604970 CR606144 BQ641440 CR598409 BQ427667 BU193152 CR617345 
    BU854825 BE207724 BU538788 BM772560 AW276496 BM908982 BM758404 CR605712 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ASF1B    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c · 4d
    SP1:                                                  -                           
    SP2:                                      -           -                           
    SP3:                                -                 -                           
    SP4:                                                                              
    SP5:                                      -     -     -                           


    ECgene alternative splicing isoforms for ASF1B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ASF1B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGGATGCTGT
    ASF1B Expression
    About this image


    ASF1B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Liver (Hepatobiliary System)
             Liver Lobule
    ASF1B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ASF1B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.26516

    UniProtKB/Swiss-Prot: ASF1B_HUMAN, Q9NVP2
    Tissue specificity: Highly expressed in testis and at lower levels in colon, small intestine and thymus

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ASF1B gene from Selected species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Asf1b1 , 5 ASF1 anti-silencing function 1 homolog B (S. cerevisiae)1, 5 87.62(n)1
    91.58(a)1
      8 (40.22 cM)5
    669291  NM_024184.21  NP_077146.11 
     839555075 
    lizard
    (Anolis carolinensis)
    Reptilia ASF1B6
    anti-silencing function 1B histone chaperone
    65(a)
    1 ↔ 1
    2(119356430-119367140)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.45262 Transcribed sequence with moderate similarity to protein more 76.4(n)    AL877193.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb20g032 Transcribed sequence with moderate similarity to protein more 76.94(n)    CF996135.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta asf16
    anti-silencing factor 1
    56(a)
    1 → many
    3L(19611994-19613498)
    worm
    (Caenorhabditis elegans)
    Secernentea asfl-16
    unc-856
    Protein UNC-85 (unc-85) mRNA, complete cds
    35(a)
    29(a)
    many ↔ many
    many ↔ many
    I(9658274-9660073) WBGene00007277
    II(4702069-4703264) WBGene00006817
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ASF1(YJL115W)4 Nucleosome assembly factor, involved in chromatin assembly more   --   10(196287-197126) 853327  NP_012420.1 
    barley
    (Hordeum vulgare)
    Liliopsida Hv.22772 Transcribed sequence with moderate similarity to protein more 79.23(n)    AL509201.1 


    ENSEMBL Gene Tree for ASF1B (if available)
    TreeFam Gene Tree for ASF1B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ASF1B gene
    ASF1A2  
    1 SIMAP similar gene for ASF1B using alignment to 5 protein entries:     ASF1B_HUMAN (see all proteins):
    ASF1A

    Find genes that share paralogs with ASF1B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ASF1B (see all 287)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1502416041,2
    --14230756(+) AAGAAA/TCTTCC 1 -- ut310--------
    rs762871601,2
    C,F--14230802(+) ACTAAC/GTAACA 1 -- ut312Minor allele frequency- G:0.06CSA WA 120
    rs1388743021,2
    --14230855(+) ATGTAC/TAGGAA 1 -- ut310--------
    rs1864101541,2
    --14230970(+) GATCAA/GTGGTA 1 -- ut310--------
    rs1494845501,2
    --14231071(+) TCTTAC/TAGGCC 1 -- ut310--------
    rs1459566831,2
    C--14231203(+) ATGGGC/TCCTGC 1 -- ut310--------
    rs1995254411,2
    C--14231240(+) CCTCCC/TGGCGT 1 -- ut310--------
    rs37454641,2
    C,F,A,H--14231243(-) AGCACG/ACCGGG 1 -- ut31 ese313Minor allele frequency- A:0.16NA WA CSA EA EU 562
    rs37454631,2
    C,F--14231256(-) CCCAGA/GGTGTC 1 -- ut31 ese36Minor allele frequency- G:0.13NA EA EU 525
    rs1396127451,2
    C,F--14231276(+) TTAGAT/CGCAGT 2 /I /V mis11Minor allele frequency- C:0.00NA 4526

    HapMap Linkage Disequilibrium report for ASF1B (14230321 - 14247768 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for ASF1B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2718213CNV Deletion23290073
    nsv517436CNV Loss19592680
    nsv833761CNV Loss17160897
    nsv911117CNV Loss21882294
    dgv49n68CNV Loss17160897
    nsv911120CNV Loss21882294
    dgv3741n71CNV Loss21882294
    dgv3739n71CNV Loss21882294
    nsv828452CNV Loss20364138
    esv22154CNV Gain19812545

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609190    OMIM disorders: --


    Find genes that share disorders with ASF1B           About GenesLikeMe

    Genetic Association Database (GAD): ASF1B
    Human Genome Epidemiology (HuGE) Navigator: ASF1B (3 documents)

    Export disorders for ASF1B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ASF1B gene, integrated from 10 sources (see all 47):
    (articles sorted by number of sources associating them with ASF1B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. (PubMed id 11897662)1, 2, 3 Mello J.A....Almouzni G. (EMBO Rep. 2002)
    2. Identification of human Asf1 chromatin assembly factors as substrates of Tousled-like kinases. (PubMed id 11470414)1, 2, 3 Sillje H.H.W. and Nigg E.A. (Curr. Biol. 2001)
    3. Transcription initiation factor IID-interactive histone chaperone CIA-II implicated in mammalian spermatogenesis. (PubMed id 12842904)1, 2, 9 Umehara T. and Horikoshi M. (J. Biol. Chem. 2003)
    4. Codanin-1, mutated in the anaemic disease CDAI, regulates Asf1 function in S-phase histone supply. (PubMed id 22407294)1, 2 Ask K.... Groth A. (EMBO J. 2012)
    5. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    6. Phosphorylation-mediated control of histone chaperone ASF1 levels by Tousled-like kinases. (PubMed id 20016786)1, 2 Pilyugin M.... Moshkin Y.M. (PLoS ONE 2009)
    7. Structure of a human ASF1a-HIRA complex and insights into specificity of histone chaperone complex assembly. (PubMed id 16980972)1, 2 Tang Y.... Marmorstein R. (Nat. Struct. Mol. Biol. 2006)
    8. Human Asf1 regulates the flow of S phase histones during replicational stress. (PubMed id 15664198)1, 2 Groth A....Almouzni G. (Mol. Cell 2005)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    10. Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. (PubMed id 14718166)1, 2 Tagami H.... Nakatani Y. (Cell 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55723 HGNC: 20996 AceView: ASF1B Ensembl:ENSG00000105011 euGenes: HUgn55723
    ECgene: ASF1B H-InvDB: ASF1B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ASF1B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ASF1B gene:
    Search GeneIP for patents involving ASF1B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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