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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ASCC3 Gene

protein-coding   GIFtS: 50
GCID: GC06M100956

activating signal cointegrator 1 complex subunit 3

(Previous names: helicase, ATP binding 1 )
(Previous symbol: HELIC1)
 Explore 6 diseases affiliated with
ASCC3 via our new
 Human Malady Compendium 
Biological research products
for ASCC3
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Activating Signal Cointegrator 1 Complex Subunit 31 2     Trip4 Complex Subunit P2002 3
Helicase, ATP Binding 11 2 3     DJ467N11.12
ASC1p2001 2 3     B630009I04Rik2
HELIC11 2 3     DJ467N11.12
RNAH1 2     P2001
DJ121G13.41     RNA Helicase Family2
ASC-1 Complex Subunit P2002 3     EC 3.6.4.123

External Ids:    HGNC: 186971   Entrez Gene: 109732   Ensembl: ENSG000001122497   OMIM: 6142175   UniProtKB: Q8N3C03   

Export aliases for ASCC3 gene to outside databases

Previous GC identifers: GC06M101063 GC06M098395


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ASCC3_HUMAN, Q8N3C0
Function: 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded
substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded
regions. Enhances NF-kappa-B, SRF and AP1 transactivation

Gene Wiki entry for ASCC3


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ASCC3 gene promoter:
         NF-1   NF-1/L   SRF (504 AA)   MEF-2   Olf-1   Lmo2   MEF-2A   POU2F1   POU2F1a   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidASCC3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ASCC3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASCC3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q16   Ensembl cytogenetic band:  6q16.3   HGNC cytogenetic band: 6q16

ASCC3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASCC3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M100956:  view genomic region     (about GC identifiers)

Start:
100,956,070 bp from pter      End:
101,329,248 bp from pter
Size:
373,179 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ASCC3_HUMAN, Q8N3C0 (See protein sequence)
Recommended Name: Activating signal cointegrator 1 complex subunit 3  
Size: 2202 amino acids; 251460 Da
Subunit: Part of TRIP4 complex, that contains ASCC1, ASCC2 and ASCC3. The TRIP4 complex interacts with ALKBH3
Subcellular location: Nucleus. Cytoplasm
Sequence caution: Sequence=AAG45474.1; Type=Frameshift; Positions=2175; Sequence=CAA11679.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=CAA11679.1; Type=Frameshift; Positions=2175;
Secondary accessions: E7EW23 O43738 Q4G1A0 Q5VTN2 Q9H1I9 Q9H5A2 Q9NTR0
Alternative splicing: 3 isoforms:  Q8N3C0-1   Q8N3C0-3   Q8N3C0-4   

Explore the universe of human proteins at neXtProt for ASCC3: NX_Q8N3C0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8N3C0

  • ASCC3 Protein expression data from MOPED and PaxDb:    About this image 
    ASCC3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_006819.2  NP_071374.1  

    ENSEMBL proteins: 
     ENSP00000358159   ENSP00000320252   ENSP00000430769   ENSP00000320777   ENSP00000358139  

    Human Recombinant Protein Products for ASCC3: 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ASCC3

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IDA--
    GO:0005634nucleus TAS--
    GO:0005737cytoplasm IEA--
    GO:0005794Golgi apparatus ----

    ASCC3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ASCC3


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ASCC3 for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR011545 DNA/RNA_helicase_DEAD/DEAH_N
     IPR003593 AAA+_ATPase
     IPR004179 Sec63-dom
     IPR014001 Helicase_ATP-bd
     IPR001650 Helicase_C

    Graphical View of Domain Structure for InterPro Entry Q8N3C0

    ProtoNet protein and cluster: Q8N3C0

    UniProtKB/Swiss-Prot: ASCC3_HUMAN, Q8N3C0
    Similarity: Belongs to the helicase family
    Similarity: Contains 2 helicase ATP-binding domains
    Similarity: Contains 2 helicase C-terminal domains
    Similarity: Contains 2 SEC63 domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASCC3_HUMAN, Q8N3C0
    Function: 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded
    substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded
    regions. Enhances NF-kappa-B, SRF and AP1 transactivation
    Catalytic activity: ATP + H(2)O = ADP + phosphate

         Enzyme Number (IUBMB): EC 3.6.4.121

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005515protein binding IPI--
    GO:0005524ATP binding IEA--
    GO:0043140ATP-dependent 3'-5' DNA helicase activity IDA--
         
    ASCC3 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for ASCC3:
     G0/1 arrest  Increased G1 DNA content  Increased circadian period len  Synthetic lethal with Ras 

         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Ascc3):
     behavior/neurological  limbs/digits/tail  other  skeleton  vision/eye 

    ASCC3 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for ASCC3 

    miRNA
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    OriGene 3'-UTR Clone (see all 2): ASCC3
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    7 QIAGEN miScript miRNA Assays for microRNAs that regulate ASCC3:
    hsa-miR-30c hsa-miR-30a hsa-miR-136* hsa-miR-196a* hsa-miR-30b hsa-miR-30d hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidASCC3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ASCC3 (see all 4)
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    OriGene siRNA: ASCC3
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    Sirion Biotech Custom design and validation of potent shRNA sequences against ASCC3 

    Gene Editing
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASCC3 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASCC3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ASCC3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/39 Interacting proteins for ASCC3 (Q8N3C02, 3 ENSP000003202524) via UniProtKB, MINT, STRING, and/or I2D (see all 39)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SKILP127572, 3MINT-61658 I2D: score=3 
    ASCC1Q8N9N23, ENSP000003204614I2D: score=1 STRING: ENSP00000320461
    EIF3FO003033, ENSP000003100404I2D: score=1 STRING: ENSP00000310040
    EIF3HO153723, ENSP000002766824I2D: score=1 STRING: ENSP00000276682
    JUNP054123, ENSP000003602664I2D: score=1 STRING: ENSP00000360266
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006307DNA dealkylation involved in DNA repair IDA--
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0008283cell proliferation IMP--
    GO:0032508DNA duplex unwinding IDA--

    ASCC3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ASCC3
    Search CenterWatch for drugs/clinical trials and news about ASCC3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ASCC3 gene (2 alternative transcripts): 
    NM_006828.2  NM_022091.3  

    Unigene Cluster for ASCC3:

    Activating signal cointegrator 1 complex subunit 3
    Hs.486031  [show with all ESTs]
    Unigene Representative Sequence: NM_006828
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369162(uc003pqk.3 uc011eai.1) ENST00000518006 ENST00000324696
    ENST00000522650(uc003pql.3) ENST00000468245(uc010kcv.3) ENST00000324723
    ENST00000369143(uc003pqm.3)

    miRNA
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    OriGene 3'-UTR Clone (see all 2): ASCC3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ASCC3
    7 QIAGEN miScript miRNA Assays for microRNAs that regulate ASCC3:
    hsa-miR-30c hsa-miR-30a hsa-miR-136* hsa-miR-196a* hsa-miR-30b hsa-miR-30d hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidASCC3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ASCC3 (see all 4)
    OriGene shRNA RFP: ASCC3
    OriGene siRNA: ASCC3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASCC3
    Sirion Biotech Custom design and validation of potent shRNA sequences against ASCC3 
    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ASCC3 (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ASCC3 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): ASCC3 (NM_006828)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASCC3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASCC3 
    Primer
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    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ASCC3
    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASCC3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASCC3

    Additional cDNA sequence: 

    AJ223948.1 AK023189.1 AK299117.1 AK307903.1 AK315197.1 AL834463.1 AY013288.1 BC014358.1 
    BC026066.1 BC039857.1 BC050681.1 BC125211.1 BC125212.1 BC130038.1 CR936692.1 

    9 DOTS entries:

    DT.442902  DT.75101017  DT.100644004  DT.100784229  DT.100784230  DT.121333145  DT.92060157  DT.99927233 
    DT.121333097 

    24/167 AceView cDNA sequences (see all 167):

    BU688613 BQ720311 CB161288 AA989030 N58930 AI206286 AY013288 BG941712 
    CK906074 BF062402 NM_022091 BP335462 BF431792 CB161009 BQ436047 BF593403 
    BQ023443 AA749406 BQ023090 AA632279 CB122307 AI889749 AL834463 AA405505 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ASCC3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTTAACTGGG
    ASCC3 Expression
    About this image
    See ASCC3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ASCC3

    SOURCE GeneReport for Unigene cluster: Hs.486031

    UniProtKB/Swiss-Prot: ASCC3_HUMAN, Q8N3C0
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASCC3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ASCC3 gene from 9/33 species (see all 33)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ASCC31 activating signal cointegrator 1 complex subunit 3 79.93(n)
    83.46(a)
      421790  XM_419816.3  XP_419816.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    ASCC36
    --
    84(a)
    74(a)
    1 ↔ many
    1 ↔ many
    1(171010478-171143199)
    1(170794105-170922334)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia 1420336552   -- 77.56(n)    142033655 
    zebrafish
    (Danio rerio)
    Actinopterygii ascc31 activating signal cointegrator 1 complex subunit 3 70.65(n)
    80.86(a)
      100332599  XM_002664026.2  XP_002664072.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG52051 CG5205 53.5(n)
    51.82(a)
      41891  NM_142215.2  NP_650472.2 
    worm
    (Caenorhabditis elegans)
    Secernentea Y54E2A.61 hypothetical protein 53.61(n)
    50.26(a)
      175136  NM_064661.2  NP_497062.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SLH11 Slh1p 55.13(n)
    49.43(a)
      853187   NP_011787.4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT5G611401 U5 small nuclear ribonucleoprotein helicase 55.85(n)
    54.31(a)
      836235  NM_001203655.1  NP_001190584.1 
    rice
    (Oryza sativa)
    Liliopsida Os.268742 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 73.57(n)    AK099757.1 


    ENSEMBL Gene Tree for ASCC3 (if available)
    TreeFam Gene Tree for ASCC3 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ASCC3 gene
    HELQ2  SNRNP2002  POLQ2  
    2 SIMAP similar genes for ASCC3 using alignment to 3 protein entries:     ASCC3_HUMAN (see all proteins):
    ASCC3L1    SNRNP200

    ASCC3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/6004 NCBI SNPs in ASCC3 are shown (see all 6004    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs58786441,2
    C--98641455(+) AACAG-/TTAAGA 1 -- int12Minor allele frequency- T:0.00NA CSA 4
    rs113458641,2
    C--98657014(+) GATCT-/AAAAAA 1 -- int1 trp32Minor allele frequency- A:0.00NA CSA 4
    rs1170098291,2
    --100956139(+) TCAGAA/CACACT 1 -- int11Minor allele frequency- C:0.01NA 120
    rs10584621,2
    C,F--100956323(-) CAAACA/GAATTC 1 -- int13Minor allele frequency- G:0.10MN NA EA 424
    rs1477832731,2
    C--100956818(+) CTGTG-/TACC  
            
    TACCA
    1 -- ut310--------
    rs1862603141,2
    --100956833(+) ACAGAG/TTTATA 1 -- ut310--------
    rs1440903691,2
    --100956984(+) TCATCC/TCAAAT 1 -- ut310--------
    rs1916078571,2
    --100957021(+) ATGCTC/TTTTCA 1 -- ut310--------
    rs790289351,2
    C,F--100957211(+) TGACTG/CAACAG 1 -- ut311Minor allele frequency- C:0.06WA 118
    rs2005353431,2
    --100957271(+) TTTAAC/TGCCAG 2 A syn10--------

    HapMap Linkage Disequilibrium report for ASCC3 (100956070 - 101206070 bp, first 250kb of ASCC3)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for ASCC3
         3 CNVs: 93914 81511 64607
         1 Indel: 93915
    Human Gene Mutation Database (HGMD): ASCC3

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ASCC3 for disorders           About GeneDecksing

    OMIM gene information: 614217    OMIM disorders: --

    6 diseases for ASCC3:    About MalaCards
    esophagitis    tuberculosis    melanoma    adenocarcinoma
    malaria    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: ASCC3 (7 documents)

    Export disorders for ASCC3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ASCC3 gene, integrated from 9 sources (see all 33):
    (articles sorted by number of sources associating them with ASCC3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. DNA unwinding by ASCC3 helicase is coupled to ALKBH3- dependent DNA alkylation repair and cancer cell proliferation. (PubMed id 22055184)1, 2 Dango S....Shi Y. (2011)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Novel transcription coactivator complex containing activating signal cointegrator 1. (PubMed id 12077347)1, 2 Jung D.-J.... Lee Y.C. (2002)
    4. Antitumor immunity at work in a melanoma patient. (PubMed id 10218103)1, 3 Coulie P.G....Chiari R. (1999)
    5. The genetic architecture of economic and political pre ferences. (PubMed id 22566634)1 Benjamin D.J....Visscher P.M. (2012)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    8. NOTCH1 nuclear interactome reveals key regulators of i ts transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10973 HGNC: 18697 AceView: ASCC3 Ensembl:ENSG00000112249 euGenes: HUgn10973
    ECgene: ASCC3 H-InvDB: ASCC3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ASCC3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ASCC3 gene:
    Search GeneIP for patents involving ASCC3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 13 May 2013

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