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ASB6 Gene

protein-coding   GIFtS: 52
GCID: GC09M132396

Ankyrin Repeat And SOCS Box Containing 6

(Previous name: ankyrin repeat and SOCS box-containing 6)
  Search for ASB6
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ankyrin Repeat And SOCS Box Containing 61 2
Ankyrin Repeat And SOCS Box-Containing 61 2
Ankyrin Repeat And SOCS Box Protein 62
ASB-63

External Ids:    HGNC: 171811   Entrez Gene: 1404592   Ensembl: ENSG000001483317   OMIM: 6150515   UniProtKB: Q9NWX53   

Export aliases for ASB6 gene to outside databases

Previous GC identifers: GC09U990201 GC09M124043 GC09M125852 GC09M127772 GC09M129476 GC09M131436 GC09M101995


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ASB6 Gene:
The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other
protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to
the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that
comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been
identified for this gene. (provided by RefSeq, Jan 2011)

GeneCards Summary for ASB6 Gene:
ASB6 (ankyrin repeat and SOCS box containing 6) is a protein-coding gene.

UniProtKB/Swiss-Prot: ASB6_HUMAN, Q9NWX5
Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of
target proteins

Gene Wiki entry for ASB6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000009.11  NT_008470.20  NC_018920.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ASB6 gene promoter:
         Egr-3   Elk-1   Pax-5   SREBP-1c   C/EBPalpha   SREBP-1b   E47   CHOP-10   SREBP-1a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidASB6 promoter sequence
   Search Chromatin IP Primers for ASB6

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ASB6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.13   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.13

ASB6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASB6 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M132396:  view genomic region     (about GC identifiers)

Start:
132,396,883 bp from pter      End:
132,404,448 bp from pter
Size:
7,566 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ASB6_HUMAN, Q9NWX5 (See protein sequence)
Recommended Name: Ankyrin repeat and SOCS box protein 6  
Size: 421 amino acids; 47136 Da
Subunit: Binds APS. Identified in a complex with TCEB1 and TCEB2 (By similarity). Interacts with CUL5 and RNF7
Secondary accessions: Q5SZB7 Q9BV15
Alternative splicing: 2 isoforms:  Q9NWX5-1   Q9NWX5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ASB6: NX_Q9NWX5

Explore proteomics data for ASB6 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ASB6 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001189332.1  NP_060343.1  NP_821066.1  

    ENSEMBL proteins: 
     ENSP00000277459   ENSP00000277458   ENSP00000416172  
    Reactome Protein details: Q9NWX5

    ASB6 Human Recombinant Protein Products:

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    Novus Biologicals ASB6 Protein
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    Cloud-Clone Corp. Proteins for ASB6

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing

    3 InterPro protein domains:
     IPR002110 Ankyrin_rpt
     IPR001496 SOCS_C
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q9NWX5

    ProtoNet protein and cluster: Q9NWX5

    2 Blocks protein domains:
    IPB001496 SOCS protein
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: ASB6_HUMAN, Q9NWX5
    Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different
    E3 ubiquitin-protein ligase complexes (By similarity)
    Similarity: Contains 6 ANK repeats
    Similarity: Contains 1 SOCS box domain


    Find genes that share domains with ASB6           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASB6_HUMAN, Q9NWX5
    Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
    ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of
    target proteins

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with ASB6           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ASB6
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ASB6

    miRNA
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    miRTarBase miRNAs that target ASB6:
    hsa-mir-130b-3p (MIRT020168), hsa-mir-16-5p (MIRT031697), hsa-mir-155-5p (MIRT020742), hsa-mir-615-3p (MIRT040182)

    Block miRNA regulation of human, mouse, rat ASB6 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate ASB6:
    hsa-miR-647 hsa-miR-22 hsa-miR-1184 hsa-miR-4288 hsa-miR-632 hsa-miR-346 hsa-miR-604
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ASB6_HUMAN, Q9NWX5: Cytoplasm (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    endoplasmic reticulum1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    Find genes that share ontologies with ASB6           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ASB6 About    
    See pathways by source

    SuperPathContained pathways About
    1Class I MHC mediated antigen processing and presentation
    Class I MHC mediated antigen processing and presentation0.84
    Adaptive Immune System0.41
    Antigen processing- Ubiquitination and Proteasome degradation0.84


    Find genes that share SuperPaths with ASB6           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for ASB6
        Antigen processing: Ubiquitination & Proteasome degradation


    UniProtKB/Swiss-Prot: ASB6_HUMAN, Q9NWX5
    Pathway: Protein modification; protein ubiquitination

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ASB6
    Interactions:

        Search GeneGlobe Interaction Network for ASB6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for ASB6 (Q9NWX52, 3 ENSP000002774584) via UniProtKB, MINT, STRING, and/or I2D (see all 10)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    RNF7Q9UBF62, 3, ENSP000002734804MINT-77971 I2D: score=2 STRING: ENSP00000273480
    CUL5Q930342, 3MINT-77972 I2D: score=2 
    SH2B2O144923, ENSP000003047014I2D: score=2 STRING: ENSP00000304701
    EWSR1Q018443I2D: score=1 
    SERTAD1Q9UHV23I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--
    GO:0035556intracellular signal transduction IEA--

    Find genes that share ontologies with ASB6           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ASB6



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ASB6 gene (3 alternative transcripts): 
    NM_001202403.1  NM_017873.3  NM_177999.2  

    Unigene Cluster for ASB6:

    Ankyrin repeat and SOCS box containing 6
    Hs.125037  [show with all ESTs]
    Unigene Representative Sequence: BX648923
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000277459 ENST00000277458(uc004bye.1 uc004byf.2 uc010myx.2 uc004byg.2 uc011mbt.2)
    ENST00000450050
    miRNA
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    7 qRT-PCR Assays for microRNAs that regulate ASB6:
    hsa-miR-647 hsa-miR-22 hsa-miR-1184 hsa-miR-4288 hsa-miR-632 hsa-miR-346 hsa-miR-604
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene qPCR primer pairs and template standards for ASB6
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      QuantiTect SYBR Green Assays in human, mouse, rat ASB6
      QuantiFast Probe-based Assays in human, mouse, rat ASB6

    Additional mRNA sequence: 

    AK000555.1 AK023004.1 AK093539.1 AK225618.1 AK292807.1 AK299193.1 AL390135.1 BC001719.1 
    BC065913.1 BX648923.1 CR627462.1 

    7 DOTS entries:

    DT.92453551  DT.100751546  DT.91889663  DT.97822889  DT.75132563  DT.97841645  DT.95159180 

    Selected AceView cDNA sequences (see all 161):

    BU153523 NM_017873 BQ058223 BQ057989 BM424237 AA482263 NM_177999 AW009753 
    AK000555 AA740995 BU183755 CA424820 CF131246 BM726456 AI360373 AI678050 
    AW292537 AA468851 AA325882 AA305172 AW473387 BE552271 BU602539 AI567851 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ASB6    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6
    SP1:                          -                 -                     
    SP2:                          -                                       
    SP3:                          -           -     -                     
    SP4:                                                                  
    SP5:                                                                  


    ECgene alternative splicing isoforms for ASB6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ASB6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATGCCCCACC
    ASB6 Expression
    About this image

    ASB6 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ASB6 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.125037
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ASB6 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Asb61 , 5 ankyrin repeat and SOCS box-containing 61, 5 83.74(n)1
    90.58(a)1
      2 (21.74 cM)5
    723231  NM_133346.21  NP_579924.11 
     308230975 
    chicken
    (Gallus gallus)
    Aves ASB61 ankyrin repeat and SOCS box containing 6 70.55(n)
    66.75(a)
      417194  NM_001030688.1  NP_001025859.1 
    lizard
    (Anolis carolinensis)
    Reptilia ASB66
    ankyrin repeat and SOCS box containing 6
    60(a)
    1 ↔ 1
    AAWZ02040296(11-6804)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC688112 hypothetical protein MGC68811 79.94(n)    BC061679.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.135892 Transcribed sequence with weak similarity to protein more 73.6(n)    BI673877.1 


    ENSEMBL Gene Tree for ASB6 (if available)
    TreeFam Gene Tree for ASB6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ASB6 gene
    1 SIMAP similar gene for ASB6 using alignment to 2 protein entries:     ASB6_HUMAN (see all proteins):
    DKFZp686H0429

    Find genes that share paralogs with ASB6           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ASB6 (see all 245)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1114326071,2
    C,F--132398485(+) GTGAAG/ACCCCG 3 -- ut312Minor allele frequency- A:0.50NA CSA 4
    rs1911800241,2
    --132398531(+) CAGGCA/GTGATG 3 -- ut310--------
    rs1821512121,2
    --132398537(+) TGATGA/GCGGGC 3 -- ut310--------
    rs44199111,2
    C,H--132398617(+) gtgagC/Gtgaga 3 -- ut31 ese37Minor allele frequency- G:0.00NA WA CSA 17
    rs1868895421,2
    C--132398627(+) ATTGCA/GCCACT 3 -- ut310--------
    rs1133177561,2
    C,F--132398698(+) GGGCCG/AGGCAC 3 -- ut311Minor allele frequency- A:0.50NA 2
    rs1433082241,2
    C--132398700(+) GCCGGA/GCACAG 3 -- ut310--------
    rs2014782541,2
    --132398786(+) GCCTG-/ACCA  
            
    ACATG
    3 -- ut310--------
    rs1928267601,2
    C--132398796(+) CATGGC/G/TGAAAC 6 -- ut310--------
    rs1848105321,2
    --132398960(+) GACAGA/TGTGTC 3 -- ut310--------

    HapMap Linkage Disequilibrium report for ASB6 (132396883 - 132404448 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ASB6:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv893924CNV Loss21882294
    nsv893919CNV Loss21882294
    nsv469901CNV Loss18288195
    nsv893923CNV Loss21882294
    nsv893909CNV Loss21882294
    nsv831731CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ASB6
    DNA2.0 Custom Variant and Variant Library Synthesis for ASB6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615051    OMIM disorders: --


    Find genes that share disorders with ASB6           About GenesLikeMe

    Genetic Association Database (GAD): ASB6

    Export disorders for ASB6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ASB6 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with ASB6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ASB proteins interact with cullin5 and Rbx2 to form E3 ubiquitin ligase complexes. (PubMed id 16325183)1, 2 Kohroki J.... Masuho Y. (FEBS Lett. 2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (J. Cell. Sci. 2012)
    5. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    6. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    7. A high-throughput approach for measuring temporal changes in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (Nat. Methods 2012)
    8. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    9. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 140459 HGNC: 17181 AceView: ASB6 Ensembl:ENSG00000148331 euGenes: HUgn140459
    ECgene: ASB6 H-InvDB: ASB6

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ASB6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ASB6 gene:
    Search GeneIP for patents involving ASB6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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