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ASB3 Gene

protein-coding   GIFtS: 50
GCID: GC02M053898

Ankyrin Repeat And SOCS Box Containing 3

(Previous name: ankyrin repeat and SOCS box-containing 3)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ankyrin Repeat And SOCS Box Containing 31 2
ASB-32 3
Ankyrin Repeat And SOCS Box-Containing 31
Ankyrin Repeat And SOCS Box Protein 32

External Ids:    HGNC: 160131   Entrez Gene: 511302   Ensembl: ENSG000002708987   OMIM: 6057605   UniProtKB: Q9Y5753   

Export aliases for ASB3 gene to outside databases

Previous GC identifers: GC02M053935 GC02M054083 GC02M053871 GC02M053808 GC02M053613 GC02M053750


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ASB3 Gene:
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of
proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of
cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly
targeting them for degradation. Alternatively spliced transcript variants have been described for this gene.
(provided by RefSeq, Jan 2011)

GeneCards Summary for ASB3 Gene:
ASB3 (ankyrin repeat and SOCS box containing 3) is a protein-coding gene. An important paralog of this gene is ASB15.

UniProtKB/Swiss-Prot: ASB3_HUMAN, Q9Y575
Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of
target proteins. Recognizes TNFRSF1B

Gene Wiki entry for ASB3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_022184.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the ASB3 gene promoter:
         FAC1   AP-1   ATF-2   Nkx2-5   c-Jun   Cdc5   Arnt   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidASB3 promoter sequence
   Search Chromatin IP Primers for ASB3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ASB3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p16.2   Ensembl cytogenetic band:  2p16.2   HGNC cytogenetic band: 2p16.2

ASB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASB3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M053898:  view genomic region     (about GC identifiers)

Start:
53,897,117 bp from pter      End:
54,087,297 bp from pter
Size:
190,181 bases      Orientation:
minus strand

1 alternative location:
Chr2- 53,759,810-54,087,170     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ASB3_HUMAN, Q9Y575 (See protein sequence)
Recommended Name: Ankyrin repeat and SOCS box protein 3  
Size: 518 amino acids; 57745 Da
Subunit: Interacts with TCEB2 and TNFRSF1B
Sequence caution: Sequence=AAI10916.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B3KPA3 D6W5B4 D6W5B5 G8JLA9 Q2TAI4 Q53TN0 Q53TN8 Q9NVZ2
Alternative splicing: 3 isoforms:  Q9Y575-1   Q9Y575-2   Q9Y575-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ASB3: NX_Q9Y575

Explore proteomics data for ASB3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ASB3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001188894.1  NP_057199.1  NP_665862.1  

    ENSEMBL proteins: 
     ENSP00000385085  
    Reactome Protein details: Q9Y575

    ASB3 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ASB3

     
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    antibodies-online proteins for ASB3 (5 products) 

     
    antibodies-online peptides for ASB3

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    antibodies-online antibodies for ASB3 (31 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing

    3 InterPro protein domains:
     IPR002110 Ankyrin_rpt
     IPR001496 SOCS_C
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y575

    ProtoNet protein and cluster: Q9Y575

    2 Blocks protein domains:
    IPB001496 SOCS protein
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: ASB3_HUMAN, Q9Y575
    Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different
    E3 ubiquitin-protein ligase complexes (By similarity)
    Similarity: Contains 11 ANK repeats
    Similarity: Contains 1 SOCS box domain


    Find genes that share domains with ASB3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASB3_HUMAN, Q9Y575
    Function: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
    ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of
    target proteins. Recognizes TNFRSF1B

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    Find genes that share ontologies with ASB3           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ASB3

    miRNA
    Products:
        
    miRTarBase miRNAs that target ASB3:
    hsa-mir-615-3p (MIRT040170), hsa-mir-335-5p (MIRT018047), hsa-mir-935 (MIRT036646)

    Block miRNA regulation of human, mouse, rat ASB3 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate ASB3:
    hsa-miR-30c hsa-miR-3163 hsa-miR-30a hsa-miR-30b hsa-miR-491-3p hsa-miR-30d hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidASB3 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton2
    cytosol2
    nucleus1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ASB3 About    
    See pathways by source

    SuperPathContained pathways About
    1Class I MHC mediated antigen processing and presentation
    Class I MHC mediated antigen processing and presentation0.84
    Adaptive Immune System0.41
    Antigen processing- Ubiquitination and Proteasome degradation0.84


    Find genes that share SuperPaths with ASB3           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1 Reactome Pathway for ASB3
        Antigen processing: Ubiquitination & Proteasome degradation


    UniProtKB/Swiss-Prot: ASB3_HUMAN, Q9Y575
    Pathway: Protein modification; protein ubiquitination

        Pathway & Disease-focused RT2 Profiler PCR Array including ASB3: 

              Ubiquitin Ligases in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for ASB3

    Selected Interacting proteins for ASB3 (Q9Y5753) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CAMKK2Q96RR43I2D: score=1 
    CUL5Q930343I2D: score=1 
    PCBD1P614573I2D: score=1 
    S100A8P051093I2D: score=1 
    S100A9P067023I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--
    GO:0035556intracellular signal transduction IEA--

    Find genes that share ontologies with ASB3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ASB3



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ASB3 gene (3 alternative transcripts): 
    NM_001201965.1  NM_016115.4  NM_145863.2  

    Unigene Cluster for ASB3:

    Ankyrin repeat and SOCS box containing 3
    Hs.40763  [show with all ESTs]
    Unigene Representative Sequence: NM_001201965
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000406625(uc002rxi.4) ENST00000498475 ENST00000459916
    miRNA
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    Block miRNA regulation of human, mouse, rat ASB3 using miScript Target Protectors
    7 qRT-PCR Assays for microRNAs that regulate ASB3:
    hsa-miR-30c hsa-miR-3163 hsa-miR-30a hsa-miR-30b hsa-miR-491-3p hsa-miR-30d hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmidASB3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ASB3
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    GenScript: all cDNA clones in your preferred vector (see all 3): ASB3 (NM_016115)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASB3
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      QuantiTect SYBR Green Assays in human, mouse, rat ASB3
      QuantiFast Probe-based Assays in human, mouse, rat ASB3

    Additional mRNA sequence: 

    AB209795.1 AF072693.1 AF156778.1 AK000985.1 AK001283.1 AK056069.1 AK091809.1 AK222595.1 
    AK222715.1 AK303133.1 AK314885.1 BC006488.2 BC009569.1 BC067475.1 BC067476.1 

    19 DOTS entries:

    DT.100879576  DT.442470  DT.100791659  DT.208760  DT.100791649  DT.120956247  DT.95275842  DT.120956231 
    DT.95275841  DT.120956268  DT.99942166  DT.120956180  DT.120956271  DT.100791656  DT.100791657  DT.120956239 
    DT.120956299  DT.92435749  DT.99967566 

    Selected AceView cDNA sequences (see all 198):

    AI824520 AI659449 NM_145863 AW591033 AX747197 BX401652 AW590647 CR590535 
    AW304358 BU741882 BF222852 BQ008535 BM719736 NM_016115 CB851924 BI522872 
    CA396323 BM832701 BX341802 BX115523 BX343364 BE391309 AI197805 BI838472 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ASB3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAATTAAAGC
    ASB3 Expression
    About this image

    ASB3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ASB3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.40763
        Pathway & Disease-focused RT2 Profiler PCR Array including ASB3: 
              Ubiquitin Ligases in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ASB3 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Asb31 , 5 ankyrin repeat and SOCS box-containing 31, 5 86.23(n)1
    83.78(a)1
      11 (18.19 cM)5
    652571  NM_023906.31  NP_076395.21 
     309543955 
    chicken
    (Gallus gallus)
    Aves ASB31 ankyrin repeat and SOCS box-containing 3 65.62(n)
    63.19(a)
      428545  NM_001031517.2  NP_001026688.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    69(a)
    1 → many
    1(262962533-262996418)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia asb31 ankyrin repeat and SOCS box containing 3 62.39(n)
    58.78(a)
      100497433  NM_001205069.1  NP_001191998.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi36b122 wufi36b12 75.52(n)   334210  BC045958.1 
    worm
    (Caenorhabditis elegans)
    Secernentea M60.76
    Protein M60.7 (M60.7) mRNA, complete cds
    20(a)
    1 → many
    X(8258486-8261175) WBGene00019782


    ENSEMBL Gene Tree for ASB3 (if available)
    TreeFam Gene Tree for ASB3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ASB3 gene
    GPR75-ASB3  ASB152  ASB22  ASB142  
    1 SIMAP similar gene for ASB3 using alignment to 1 protein entry:     ASB3_HUMAN:
    GPR75-ASB3

    Find genes that share paralogs with ASB3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    8 SNPs for ASB3    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1163568911,2
    C,F--53896688(+) TTAAAG/CATGGT 3 -- ds50011Minor allele frequency- C:0.02WA 118
    rs1147707611,2
    C,F--53896725(+) CTGATT/GAAAAT 3 -- ds50011Minor allele frequency- G:0.02NA 120
    rs1424969001,2
    --53896763(+) CTCAAA/CACTGA 3 -- ds50010--------
    rs9944841,2
    C,F,O,A,H--53896767(+) AAACTG/CAAACC 3 -- ds500120Minor allele frequency- C:0.14MN NS EA NA WA CSA 2526
    rs1467281081,2
    C--53896849(+) GTTGG-/TTTTGTT 3 -- ds50010--------
    rs3762731491,2
    ----53896853(+) GTTTTG/TTTTGT 3 -- ds50010--------
    rs3775759541,2
    ----53896663(+) CACCAC/TCCCGG 3 -- ds50010--------
    rs607251561,2
    ----53896923(+) ATTTTC/TTATGT 3 -- ds50010--------

    HapMap Linkage Disequilibrium report for ASB3 (53897117 - 54087297 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ASB3:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2661223CNV Deletion23128226
    esv2720076CNV Deletion23290073
    nsv2730CNV Insertion18451855
    nsv834058CNV Gain+Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ASB3
    DNA2.0 Custom Variant and Variant Library Synthesis for ASB3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605760    OMIM disorders: --


    Find genes that share disorders with ASB3           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: ASB3 (1 document)

    Export disorders for ASB3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ASB3 gene, integrated from 10 sources (see all 20):
    (articles sorted by number of sources associating them with ASB3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II. (PubMed id 15899873)1, 2, 3 Chung A.S.... Chin Y.E. (Mol. Cell. Biol. 2005)
    2. Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4. (PubMed id 11111040)1, 2, 9 Kile B.T....Alexander W.S. (Gene 2000)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    6. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (Nat. Methods 2013)
    7. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    8. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51130 HGNC: 16013 AceView: ASB3 Ensembl:ENSG00000270898 euGenes: HUgn51130
    ECgene: ASB3 H-InvDB: ASB3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ASB3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ASB3 gene:
    Search GeneIP for patents involving ASB3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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