Aliases for ASB2 Gene
Aliases for ASB2 Gene
External Ids for ASB2 Gene
- HGNC: 16012
- Entrez Gene: 51676
- Ensembl: ENSG00000100628
- OMIM: 605759
- UniProtKB: Q96Q27
Previous GeneCards Identifiers for ASB2 Gene
- GC14M091907
- GC14M088217
- GC14M092390
- GC14M093470
- GC14M094400
- GC14M074580
Summaries for ASB2 Gene
-
This gene encodes a member of the ankyrin repeat and SOCS box-containing (ASB) protein family. These proteins play a role in protein degradation by coupling suppressor of cytokine signalling (SOCS) proteins with the elongin BC complex. The encoded protein is a subunit of a multimeric E3 ubiquitin ligase complex that mediates the degradation of actin-binding proteins. This gene plays a role in retinoic acid-induced growth inhibition and differentiation of myeloid leukemia cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
GeneCards Summary for ASB2 Gene
ASB2 (Ankyrin Repeat And SOCS Box Containing 2) is a Protein Coding gene. Diseases associated with ASB2 include Leukemia, Acute Promyelocytic, Somatic. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is ASB14.
UniProtKB/Swiss-Prot for ASB2 Gene
-
Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
-
Isoform 1: Enhances adhesion of hematopoietic cells to fibronectin through targeting of filamins FLNA and FLNB for proteasomal degradation, it is transiantly expressed during hematopoietic cell differentiation.
-
Isoform 2: Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ASB2 Gene
Genomics for ASB2 Gene
Regulatory Elements for ASB2 Gene
Enhancers for ASB2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ASB2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for ASB2 Gene
- Chromosome:
- 14
- Start:
- 93,934,153 bp from pter
- End:
- 93,976,791 bp from pter
- Size:
- 42,639 bases
- Orientation:
- Minus strand
Genomic View for ASB2 Gene
Genes around ASB2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 14q32.12 by Ensembl
- 14q32.12 by Entrez Gene
- 14q32.12 by HGNC
ASB2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ASB2 Gene
Proteins for ASB2 Gene
-
Protein details for ASB2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q96Q27-ASB2_HUMAN
- Recommended name:
- Ankyrin repeat and SOCS box protein 2
- Protein Accession:
- Q96Q27
- B2RDP9
- B4E166
- Q9NSU5
- Q9Y567
Protein attributes for ASB2 Gene
- Size:
- 587 amino acids
- Molecular mass:
- 65084 Da
- Quaternary structure:
-
- Component of a probable ECS E3 ubiquitin-protein ligase complex which contains CUL5, either RBX1 or RNF7/RBX2, Elongin BC complex (ELOB and ELOC) and ASB2.
Protein Expression for ASB2 Gene
Post-translational modifications for ASB2 Gene
Other Protein References for ASB2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for ASB2
- Invitrogen Antibodies for ASB2
- antibodies-online Antibodies for ASB2: See all 44
- GeneTex Igfbp6 antibody for ASB2
- GeneTex ASB2 antibody for ASB2
Protein Products
-
OriGene Purified Proteins for ASB2
- Search Origene for MassSpec and Protein Over-expression Lysates for ASB2
- Origene Custom Protein Services for ASB2
- Novus Biologicals proteins for ASB2
- antibodies-online Proteins for ASB2: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ASB2
-
ProSci Proteins for ASB2
Assay Products
- antibodies-online Kits for ASB2: See all 11
No data available for DME Specific Peptides for ASB2 Gene
Domains & Families for ASB2 Gene
Gene Families for ASB2 Gene
Protein Domains for ASB2 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ASB2 Gene
Graphical View of Domain Structure for InterPro Entry
Q96Q27UniProtKB/Swiss-Prot:
ASB2_HUMAN :- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
- Belongs to the ankyrin SOCS box (ASB) family.
- Domain:
-
- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
- Both the N-terminus and ANK repeats 1 to 10 are necessary for interaction with filamins.
- Family:
-
- Belongs to the ankyrin SOCS box (ASB) family.
Function for ASB2 Gene
Molecular function for ASB2 Gene
- UniProtKB/Swiss-Prot Function:
- Substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
- UniProtKB/Swiss-Prot Function:
- Isoform 1: Enhances adhesion of hematopoietic cells to fibronectin through targeting of filamins FLNA and FLNB for proteasomal degradation, it is transiantly expressed during hematopoietic cell differentiation.
- UniProtKB/Swiss-Prot Function:
- Isoform 2: Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA.
- UniProtKB/Swiss-Prot Induction:
- By all-trans retinoic acid (ATRA).
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 16325183 |
| GO:0061630 | ubiquitin protein ligase activity | IEA | -- |
Phenotypes for ASB2 Gene
- MGI mutant phenotypes for ASB2:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ASB2:
-
- Increased vaccinia virus (VACV) infection
- Dynamic nuclei (hole, folded or small irregular)
- Decreased viability after sindbis virus (SIN) dsTE12Q infection
- Decreased mitophagy mCherry-Parkin protein expression after carbonyl cyanide m-chlorphenylhydrazone (CCCP) stimulation
- Decreased Sindbis virus (SIN) capsid and autophagosome LC3 protein colocalization
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
-
ViGene Biosciences lentiviral particle packaged cDNA for ASB2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB2 gene
- Search ViGene Biosciences for ASB2
CRISPR Products
-
OriGene CRISPR knockouts for ASB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASB2
- GenScript: Design CRISPR guide RNA sequences for ASB2
miRNA for ASB2 Gene
- miRTarBase miRNAs that target ASB2
miRNA Products
- Search ViGene Biosciences for ASB2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ASB2
- Browse OriGene Inhibitory RNA Products For ASB2
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB2 gene
Clone Products
- Sino Biological Human cDNA Clone for ASB2
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- VectorBuilder custom plasmid, inducible vectors for ASB2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASB2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ASB2
-
ViGene Biosciences adenoviral particle packaged cDNA for ASB2 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ASB2 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB2 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ASB2 Gene
Localization for ASB2 Gene
| Compartment | Confidence |
|---|---|
| mitochondrion | 3 |
| cytosol | 3 |
| extracellular | 1 |
| nucleus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0031466 | Cul5-RING ubiquitin ligase complex | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for ASB2 Gene
Pathways & Interactions for ASB2 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Innate Immune System |
.61
|
|
Pathways by source for ASB2 Gene
UniProtKB/Swiss-Prot Q96Q27-ASB2_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for ASB2 Gene
Selected Interacting proteins:
Q96Q27-ASB2_HUMAN
ENSP00000451575
for ASB2 Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000209 | protein polyubiquitination | IEA | -- |
| GO:0007165 | signal transduction | TAS | 9419338 |
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0035556 | intracellular signal transduction | IEA | -- |
| GO:0035914 | skeletal muscle cell differentiation | IEA | -- |
No data available for SIGNOR curated interactions for ASB2 Gene
Transcripts for ASB2 Gene
mRNA/cDNA for ASB2 Gene
- (6) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (79) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ASB2 Gene
CRISPR Products
-
OriGene CRISPR knockouts for ASB2
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASB2
- GenScript: Design CRISPR guide RNA sequences for ASB2
miRNA Products
- Search ViGene Biosciences for ASB2
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ASB2
- Browse OriGene Inhibitory RNA Products For ASB2
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB2 gene
Clone Products
- Sino Biological Human cDNA Clone for ASB2
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ASB2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASB2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | ^ | 8a | · | 8b | ^ | 9 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | |||||||||||||||||||||||||||||||
| SP2: | - | - | |||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | |||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | ||||||||||||||||||||||||||||||||
| SP6: | - | - |
Expression for ASB2 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Heart (Cardiovascular System)
- Atrioventricular Canal Cells Atrioventricular Canal
- Outflow Tract
- Cardiomyocyte-like progenitor cells(Uosaki H et. al. 2011)
- Gut Tube (Gastrointestinal Tract)
-
Skeletal Muscle (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for ASB2 Gene
This gene is overexpressed in Muscle - Skeletal (x21.0) and Heart - Left Ventricle (x4.8).
This gene is overexpressed in Ovary (64.6).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for ASB2 Gene
NURSA nuclear receptor signaling pathways regulating expression of ASB2 Gene:
ASB2SOURCE GeneReport for Unigene cluster for ASB2 Gene:
Hs.510327Evidence on tissue expression from TISSUES for ASB2 Gene
- Blood(4.2)
- Kidney(4.1)
- Stomach(4.1)
- Muscle(3.5)
- Heart(2.2)
- Intestine(2.1)
Primer Products
-
OriGene qPCR primer pairs for ASB2
-
OriGene qPCR primer pairs and template standards for ASB2
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ASB2 Gene
Orthologs for ASB2 Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ASB2 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ASB2 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ASB2 34 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Asb2 34 |
|
||
| mouse (Mus musculus) |
Mammalia | Asb2 34 16 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ASB2 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ASB2 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ASB2 34 35 |
|
||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | asb2 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | asb2a.1 34 35 35 |
|
||
| asb2b 35 |
|
OneToMany | |||
| worm (Caenorhabditis elegans) |
Secernentea | M60.7 35 |
|
OneToMany |
- Species where no ortholog for ASB2 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ASB2 Gene
(16) SIMAP similar genes for ASB2 Gene using alignment to 5 proteins:
Variants for ASB2 Gene
| SNP ID | Clin | Chr 14 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000018661 | -- | 93,966,398(+) | GGGGT(C/G)CTCCT | intron-variant | |
| rs1000030441 | -- | 93,959,910(+) | GCTAA(C/T)AAAAT | intron-variant | |
| rs1000159675 | -- | 93,965,190(+) | TTTCC(A/G)TTCCA | intron-variant | |
| rs1000218839 | -- | 93,956,244(+) | GATTA(A/T)TTCTG | intron-variant, upstream-variant-2KB | |
| rs1000250185 | -- | 93,955,668(+) | CTGCC(A/G)CCCAG | intron-variant, upstream-variant-2KB |
Residual Variation Intolerance Score:
93.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.66;
65.77% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ASB2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ASB2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ASB2 Gene
Disorders for ASB2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| leukemia, acute promyelocytic, somatic |
|
Search ASB2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ASB2
No data available for UniProtKB/Swiss-Prot and Genatlas for ASB2 Gene
Publications for ASB2 Gene
- ASB2 is an elongin BC-interacting protein that can assemble with cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex. (PMID: 15590664) Heuze M.L. … Lutz P.G. (J. Biol. Chem. 2005) 3 4 22 64
- ASB-2 inhibits growth and promotes commitment in myeloid leukemia cells. (PMID: 11682484) Guibal F.C. … Cayre Y.E. (J. Biol. Chem. 2002) 3 4 22 64
- ATRA-regulated Asb-2 gene induced in differentiation of HL-60 leukemia cells. (PMID: 11566180) Kohroki J. … Tanaka K. (FEBS Lett. 2001) 3 4 22 64
- Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4. (PMID: 11111040) Kile B.T. … Alexander W.S. (Gene 2000) 3 4 22 64
- ASB2I+, an E3 ubiquitin ligase specificity subunit, regulates cell spreading and triggers proteasomal degradation of filamins by targeting the filamin calponin homology 1 domain. (PMID: 24052262) Razinia Z. … Calderwood D.A. (J. Biol. Chem. 2013) 3 4 64
Products for ASB2 Gene
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- Novus Biologicals Antibodies for ASB2
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- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for ASB2: See all 44
- antibodies-online Kits for ASB2: See all 11
- antibodies-online Proteins for ASB2: See all 4
- Search antibodies-online for peptides
- GeneTex Igfbp6 antibody for ASB2
- GeneTex ASB2 antibody for ASB2
- Search GeneTex for Proteins for ASB2
- ViGene Biosciences adenoviral particle packaged cDNA for ASB2 gene
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- Search for ASB2 Antibodies at ProSci
- Custom Antibody Services
- ProSci Proteins for ASB2
- Horizon Cell Lines for ASB2
- Cyagen custom Knockout/knockin (KOKI) mouse models for ASB2
- VectorBuilder custom plasmid, inducible vectors for ASB2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASB2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ASB2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
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