Aliases for ASB15 Gene
External Ids for ASB15 Gene
Previous GeneCards Identifiers for ASB15 Gene
This gene encodes a member of the suppressor of cytokine signaling box superfamily. The proteins in this superfamily participate in the ubiquitin-proteasome system for the degradation of proteins in the cell cycle and signal transduction pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
GeneCards Summary for ASB15 Gene
ASB15 (Ankyrin Repeat And SOCS Box Containing 15) is a Protein Coding gene. Diseases associated with ASB15 include Retinitis Pigmentosa 11. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is ASB14.
UniProtKB/Swiss-Prot for ASB15 Gene
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.