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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ASB10 Gene

protein-coding   GIFtS: 50
GCID: GC07M150872

Ankyrin Repeat And SOCS Box Containing 10

(Previous name: ankyrin repeat and SOCS box-containing 10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ankyrin Repeat And SOCS Box Containing 101 2
Ankyrin Repeat And SOCS Box-Containing 101
GLC1F2
Ankyrin Repeat And SOCS Box Protein 102
ASB-103

External Ids:    HGNC: 171851   Entrez Gene: 1363712   Ensembl: ENSG000001469267   OMIM: 6150545   UniProtKB: Q8WXI33   

Export aliases for ASB10 gene to outside databases

Previous GC identifers: GC07M149119 GC07M150187 GC07M150264 GC07M150310 GC07M150503 GC07M144683


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ASB10 Gene:
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of
proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding
partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively
spliced transcript variants have been described for this gene. (provided by RefSeq, Dec 2008)

GeneCards Summary for ASB10 Gene: 
ASB10 (ankyrin repeat and SOCS box containing 10) is a protein-coding gene. Diseases associated with ASB10 include primary open angle glaucoma, and glaucoma, and among its related super-pathways are Class I MHC mediated antigen processing & presentation and Immune System. An important paralog of this gene is ASB16.

UniProtKB/Swiss-Prot: ASB10_HUMAN, Q8WXI3
Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of
target proteins (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007914.15  NC_018918.2  NT_079596.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ASB10 gene promoter:
         POU2F1   POU2F1a   c-Myb   USF2   HNF-4alpha2   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ASB10 promoter sequence
   Search SABiosciences Chromatin IP Primers for ASB10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ASB10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q35

ASB10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ASB10 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M150872:  view genomic region     (about GC identifiers)

Start:
150,872,785 bp from pter      End:
150,884,919 bp from pter
Size:
12,135 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 150,202,306-150,214,439     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ASB10_HUMAN, Q8WXI3 (See protein sequence)
Recommended Name: Ankyrin repeat and SOCS box protein 10  
Size: 467 amino acids; 50894 Da
Secondary accessions: A0AVH0 Q6ZUL6
Alternative splicing: 3 isoforms:  Q8WXI3-1   Q8WXI3-2   Q8WXI3-3   

Explore the universe of human proteins at neXtProt for ASB10: NX_Q8WXI3

Explore proteomics data for ASB10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WXI3

  • ASB10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ASB10 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001135931.2  NP_001135932.2  NP_543147.2  

    ENSEMBL proteins: 
     ENSP00000275838   ENSP00000367098   ENSP00000391137   ENSP00000410871   ENSP00000401369  
     ENSP00000398247  
    Reactome Protein details: Q8WXI3
    Human Recombinant Protein Products for ASB10: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ASB10
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    Novus Biologicals ASB10 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ASB10 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--

    ASB10 for ontologies           About GeneDecksing



    ASB10 Antibody Products: 
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    Cloud-Clone Corp. CLIAs for ASB10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing

    3 InterPro protein domains:
     IPR001496 SOCS_C
     IPR020683 Ankyrin_rpt-contain_dom
     IPR002110 Ankyrin_rpt

    Graphical View of Domain Structure for InterPro Entry Q8WXI3

    ProtoNet protein and cluster: Q8WXI3

    2 Blocks protein domains:
    IPB001496 SOCS protein
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: ASB10_HUMAN, Q8WXI3
    Domain: The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different
    E3 ubiquitin-protein ligase complexes (By similarity)
    Similarity: Contains 7 ANK repeats
    Similarity: Contains 1 SOCS box domain


    ASB10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ASB10_HUMAN, Q8WXI3
    Function: May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3
    ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of
    target proteins (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    ASB10 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ASB10:
     Increased cell death HMECs cel  Synthetic lethal with Ras 

         1 MGI phenotypic allele for Asb10 (no phenotypes)

    ASB10 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ASB10 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ASB10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ASB10 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ASB10 

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    1 QIAGEN miScript miRNA Assays for microRNA that regulate ASB10:
    hsa-miR-370
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASB10


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ASB10 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Antigen processing: Ubiquitination & Proteasome degradation
    Antigen processing: Ubiquitination & Proteasome degradation0.83
    Class I MHC mediated antigen processing & presentation0.83
    2Immune System
    Immune System0.56
    Adaptive Immune System0.56

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    4        Reactome Pathways for ASB10
        Antigen processing: Ubiquitination & Proteasome degradation
    Adaptive Immune System
    Class I MHC mediated antigen processing & presentation
    Immune System


    UniProtKB/Swiss-Prot: ASB10_HUMAN, Q8WXI3
    Pathway: Protein modification; protein ubiquitination


    ASB10 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ASB10

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for ASB10 (ENSP000004013694) via UniProtKB, MINT, STRING, and/or I2D

    InteractantInteraction Details
    GeneCardExternal ID(s)
    AGR3ENSP000003086064STRING: ENSP00000308606
    ARFGAP1ENSP000003146154STRING: ENSP00000314615
    MRPL23ENSP000003709304STRING: ENSP00000370930
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--
    GO:0035556intracellular signal transduction IEA--

    ASB10 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ASB10

    Search CenterWatch for drugs/clinical trials and news about ASB10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ASB10 gene (3 alternative transcripts): 
    NM_001142459.1  NM_001142460.1  NM_080871.3  

    Unigene Cluster for ASB10:

    Ankyrin repeat and SOCS box containing 10
    Hs.647081  [show with all ESTs]
    Unigene Representative Sequence: NM_001142459
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000275838 ENST00000377867(uc003wjn.1) ENST00000420175 ENST00000415615
    ENST00000422024(uc003wjm.1) ENST00000434669(uc003wjl.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ASB10
    1 QIAGEN miScript miRNA Assays for microRNA that regulate ASB10:
    hsa-miR-370
    SwitchGear 3'UTR luciferase reporter plasmidASB10 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ASB10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ASB10
    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 3): ASB10 (NM_080871)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ASB10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ASB10
    Sirion Biotech Customized lentivirus for stable overexpression of ASB10 
                         Customized lentivirus expression plasmids for stable overexpression of ASB10 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ASB10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ASB10

    Additional mRNA sequence: 

    AF417920.1 AK055536.1 AK125565.1 AK315114.1 BC126351.1 

    4 DOTS entries:

    DT.97807259  DT.65286974  DT.101963834  DT.121116557 

    19 AceView cDNA sequences:

    AK055536 NM_080871 CD635987 CD636003 CD635993 CD636008 F29396 CD636009 
    CD636006 CD636001 AK125565 CD635999 CD635991 AF417920 CD635989 CD635985 
    CD635997 CD635995 F34490 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ASB10    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:              -     -     -     -     -                                 
    SP2:                                                                        
    SP3:                                                        -               
    SP4:                    -     -                                             


    ECgene alternative splicing isoforms for ASB10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ASB10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ASB10 Expression
    About this image


    See ASB10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ASB10

    SOURCE GeneReport for Unigene cluster: Hs.647081
        SABiosciences Custom PCR Arrays for ASB10
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ASB10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for ASB10 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Asb105 ankyrin repeat and SOCS box-containing 10   --   5 (11.93 cM) 24532697 
    chicken
    (Gallus gallus)
    Aves ASB101 ankyrin repeat and SOCS box containing 10 62.1(n)
    53.06(a)
      768438  XM_001231361.2  XP_001231362.2 
    zebrafish
    (Danio rerio)
    Actinopterygii asb101 ankyrin repeat and SOCS box containing 10 56.13(n)
    49.14(a)
      559467  NM_001077148.1  NP_001070616.1 


    ENSEMBL Gene Tree for ASB10 (if available)
    TreeFam Gene Tree for ASB10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ASB10 gene
    ASB162  ASB182  ASB42  
    5 SIMAP similar genes for ASB10 using alignment to 4 protein entries:     ASB10_HUMAN (see all proteins):
    PPP1R12A    ASB18    GABPB1    ASB16    ASB4

    ASB10 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/376 SNPs in ASB10 are shown (see all 376)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1048864861,2
    C,Funtested1154325398(-) AGGTCG/ACTGCA 6 /S syn13Minor allele frequency- A:0.01NA EU 4945
    rs1513446121,2
    Cuntested1154330118(-) CGTCCA/GTGTCT 6 H R mis10--------
    rs1048864841,2
    Cuntested1154330119(-) CCGTCC/TGTGTC 6 R C mis11Minor allele frequency- T:0.00NA 3136
    rs1048864831,2
    Cuntested1154330151(-) GCACGC/TGGTTC 6 A V mis10--------
    rs617344071,2
    C,Funtested1154330173(+) GGCCAG/AGGCTG 6 /L syn13Minor allele frequency- A:0.00NS NA EU 4559
    rs1048864811,2
    C,Funtested1154330211(-) ACACAC/TGCCCC 6 T M mis12Minor allele frequency- T:0.00NA EU 5095
    rs1513446101,2
    Cuntested1154330239(-) TCAGCA/GCCAAC 6 T A mis10--------
    rs617351301,2
    C,Funtested1154330287(+) GCCACG/AGCGGC 6 /R /C mis13Minor allele frequency- A:0.00NS NA EU 4743
    rs1513446091,2
    Cuntested1154330313(-) CAAGCA/TGCGAC 6 Q L mis10--------
    rs1406029731,2
    Cuntested1154330382(+) GGCAGC/TGGGCG 6 H R mis11Minor allele frequency- T:0.00NA 4154

    HapMap Linkage Disequilibrium report for ASB10 (150872785 - 150884919 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ASB10:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv831188CNV Loss17160897
    dgv7545n71CNV Loss21882294
    nsv889476CNV Loss21882294


    Human Gene Mutation Database (HGMD): ASB10
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing ASB10
    DNA2.0 Custom Variant and Variant Library Synthesis for ASB10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 615054    OMIM disorders: --

    3 diseases for ASB10:    About MalaCards
    primary open angle glaucoma    glaucoma    open-angle glaucoma

    1 disease from the University of Copenhagen DISEASES database for ASB10:
    Primary open angle glaucoma

    ASB10 for disorders           About GeneDecksing


    Export disorders for ASB10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ASB10 gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with ASB10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. A Y2H-seq approach defines the human protein methyltransferase interactome. (PubMed id 23455924)1 Weimann M.... Stelzl U. (2013)
    4. Ankyrin repeat and suppressor of cytokine signaling bo x containing protein-10 is associated with ubiquitin-mediated degradation pathwa ys in trabecular meshwork cells. (PubMed id 23901248)1 Keller K.E....Wirtz M.K. (2013)
    5. Analysis of ASB10 variants in open angle glaucoma. (PubMed id 22798626)1 Fingert J.H....Alward W.L. (2012)
    6. Variants in ASB10 are associated with open-angle glauc oma. (PubMed id 22156576)1 Pasutto F....Wirtz M.K. (2012)
    7. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    9. ASB proteins interact with cullin5 and Rbx2 to form E3 ubiquitin ligase complexes. (PubMed id 16325183)1 Kohroki J.... Masuho Y. (2005)
    10. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1 Scherer S.W.... Tsui L.-C. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 136371 HGNC: 17185 AceView: ASB10 Ensembl:ENSG00000146926 euGenes: HUgn136371
    ECgene: ASB10 H-InvDB: ASB10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ASB10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ASB10 gene:
    Search GeneIP for patents involving ASB10

    GeneCards and IP:
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