Aliases for ASB10 Gene
Aliases for ASB10 Gene
External Ids for ASB10 Gene
- HGNC: 17185
- Entrez Gene: 136371
- Ensembl: ENSG00000146926
- OMIM: 615054
- UniProtKB: Q8WXI3
Previous HGNC Symbols for ASB10 Gene
- GLC1F
Previous GeneCards Identifiers for ASB10 Gene
- GC07M149119
- GC07M150187
- GC07M150264
- GC07M150310
- GC07M150503
- GC07M150872
- GC07M144683
Summaries for ASB10 Gene
-
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. The SOCS box serves to couple suppressor of cytokine signaling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2008]
GeneCards Summary for ASB10 Gene
ASB10 (Ankyrin Repeat And SOCS Box Containing 10) is a Protein Coding gene. Diseases associated with ASB10 include Glaucoma 1, Open Angle, F and Rieger Syndrome, Type 2. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. An important paralog of this gene is ASB18.
UniProtKB/Swiss-Prot for ASB10 Gene
-
May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ASB10 Gene
Genomics for ASB10 Gene
Regulatory Elements for ASB10 Gene
Enhancers for ASB10 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ASB10 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ASB10 gene promoter:
Regulatory Element Products
Genomic Location for ASB10 Gene
- Chromosome:
- 7
- Start:
- 151,175,698 bp from pter
- End:
- 151,187,832 bp from pter
- Size:
- 12,135 bases
- Orientation:
- Minus strand
Genomic View for ASB10 Gene
Genes around ASB10 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 7q36.1 by Ensembl
- 7q36.1 by Entrez Gene
- 7q36.1 by HGNC
ASB10 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ASB10 Gene
Proteins for ASB10 Gene
-
Protein details for ASB10 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8WXI3-ASB10_HUMAN
- Recommended name:
- Ankyrin repeat and SOCS box protein 10
- Protein Accession:
- Q8WXI3
- A0AVH0
- Q6ZUL6
Protein attributes for ASB10 Gene
- Size:
- 467 amino acids
- Molecular mass:
- 50894 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for ASB10 Gene
Other Protein References for ASB10 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
-
Custom Antibody ServicesOriGene Antibodies for ASB10
- Novus Biologicals Antibodies for ASB10
- antibodies-online Antibodies for ASB10: See all 25
- Search GeneTex for Antibodies for ASB10
-
Santa Cruz Biotechnology (SCBT) Antibodies for ASB10
Protein Products
-
OriGene Purified Proteins for ASB10
- Search Origene for MassSpec and Protein Over-expression Lysates for ASB10
- Origene Custom Protein Services for ASB10
- Novus Biologicals proteins for ASB10
- antibodies-online Proteins for ASB10: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ASB10
Assay Products
- antibodies-online Kits for ASB10: See all 9
No data available for DME Specific Peptides for ASB10 Gene
Domains & Families for ASB10 Gene
Gene Families for ASB10 Gene
Protein Domains for ASB10 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ASB10 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8WXI3UniProtKB/Swiss-Prot:
ASB10_HUMAN :- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
- Belongs to the ankyrin SOCS box (ASB) family.
- Domain:
-
- The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin-protein ligase complexes.
- Family:
-
- Belongs to the ankyrin SOCS box (ASB) family.
Function for ASB10 Gene
Molecular function for ASB10 Gene
- UniProtKB/Swiss-Prot Function:
- May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | IBA | -- |
| GO:0031625 | ubiquitin protein ligase binding | IBA | -- |
Phenotypes for ASB10 Gene
- MGI mutant phenotypes for ASB10:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for ASB10:
-
- Synthetic lethal with Ras
- Increased transferrin (TF) endocytosis
- Transferrin accumulation in the perinuclear area
- Negative genetic interaction between PTTG1-/- and PTTG1+/+
- Increased cell death HMECs cells
- Weakly decreased NFAT1-GFP nuclear translocation
- Decreased cell proliferation
- Increased simian virus 40 (SV40) infection
Animal Models for ASB10 Gene
- MGI Knock Outs for ASB10:
-
- Asb10 tm2b(KOMP)Wtsi
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ASB10
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ASB10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB10 gene
- Search ViGene Biosciences for ASB10
CRISPR Products
-
OriGene CRISPR knockouts for ASB10
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASB10
- GenScript: Design CRISPR guide RNA sequences for ASB10
miRNA Products
- Search ViGene Biosciences for ASB10
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ASB10
- Browse OriGene Inhibitory RNA Products For ASB10
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB10 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ASB10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASB10
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ASB10
-
ViGene Biosciences adenoviral particle packaged cDNA for ASB10 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ASB10 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB10 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for ASB10 Gene
Localization for ASB10 Gene
Subcellular locations from UniProtKB/Swiss-Prot for ASB10 Gene
- Cytoplasm. Nucleus. Note=In the ciliary body, it is detected in the cytoplasm and perinuclear region of the pigmented ciliary epithelial layer. In the retina, it is detected in the nuclei of retinal ganglion cells.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| extracellular | 3 |
| cytosol | 2 |
| lysosome | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000151 | ubiquitin ligase complex | IBA | -- |
| GO:0005622 | intracellular | IEA | -- |
| GO:0005634 | nucleus | IDA,IEA | 22156576 |
| GO:0005737 | cytoplasm | IEA,IDA | 22156576 |
| GO:0005829 | cytosol | TAS | -- |
Pathways & Interactions for ASB10 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Class I MHC mediated antigen processing and presentation | ||
| 2 | Innate Immune System |
.61
|
|
Pathways by source for ASB10 Gene
4 Reactome pathways for ASB10 Gene
UniProtKB/Swiss-Prot Q8WXI3-ASB10_HUMAN
- Pathway: Protein modification; protein ubiquitination.
Interacting Proteins for ASB10 Gene
Selected Interacting proteins:
Q8WXI3-ASB10_HUMAN
ENSP00000391137
for ASB10 Gene via
MINT
STRING
IID
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016567 | protein ubiquitination | IEA | -- |
| GO:0035556 | intracellular signal transduction | IEA | -- |
| GO:0043687 | post-translational protein modification | TAS | -- |
No data available for SIGNOR curated interactions for ASB10 Gene
Transcripts for ASB10 Gene
mRNA/cDNA for ASB10 Gene
- (3) REFSEQ mRNAs :
- (5) Additional mRNA sequences :
- (19) Selected AceView cDNA sequences:
- (4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ASB10 Gene
- Ankyrin repeat and SOCS box containing 10:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for ASB10
-
Santa Cruz Biotechnology (SCBT) CRISPR for ASB10
- GenScript: Design CRISPR guide RNA sequences for ASB10
miRNA Products
- Search ViGene Biosciences for ASB10
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ASB10
- Browse OriGene Inhibitory RNA Products For ASB10
-
ViGene Biosciences ready-to-package AAV shRNAs for ASB10 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for ASB10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASB10
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | ||||||||||||||||||
| SP2: | |||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||
| SP4: | - | - |
Expression for ASB10 Gene
mRNA differential expression in normal tissues according to GTEx for ASB10 Gene
This gene is overexpressed in Muscle - Skeletal (x27.3), Heart - Left Ventricle (x17.2), and Heart - Atrial Appendage (x6.1).
NURSA nuclear receptor signaling pathways regulating expression of ASB10 Gene:
ASB10SOURCE GeneReport for Unigene cluster for ASB10 Gene:
Hs.647081mRNA Expression by UniProt/SwissProt for ASB10 Gene:
Q8WXI3-ASB10_HUMAN
Tissue specificity:
Expressed in the eye. The highest expression is observed in the iris, with moderate levels in the trabecular meshwork (TM), the lamina, and the optic nerve; slightly lower levels in the ciliary body, retina, and choroid; and very low levels in the lens.
Evidence on tissue expression from TISSUES for ASB10 Gene
- Muscle(4.3)
Phenotype-based relationships between genes and organs from Gene ORGANizer for ASB10 Gene
Germ Layers:
- ectoderm
Systems:
- nervous
Organs:
Head and neck:
- brain
- eye
- head
Primer Products
-
OriGene qPCR primer pairs for ASB10
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for ASB10 Gene
Orthologs for ASB10 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ASB10 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ASB10 35 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | ASB10 35 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Asb10 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Asb10 34 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | ASB10 35 |
|
OneToOne | |
| oppossum (Monodelphis domestica) |
Mammalia | ASB10 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ASB10 35 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | asb10 35 |
|
OneToOne |
- Species where no ortholog for ASB10 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for ASB10 Gene
(5) SIMAP similar genes for ASB10 Gene using alignment to 4 proteins:
Variants for ASB10 Gene
| SNP ID | Clin | Chr 07 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs104886474 | Pathogenic, Glaucoma 1, open angle, F (GLC1F) [MIM:603383] | 151,181,424(-) | CGAGA(C/G)TGGAT | reference, missense | |
| rs104886482 | untested, Glaucoma 1, open angle, F (GLC1F) [MIM:603383] | 151,181,047(-) | CTGCA(C/G)TGTGC | reference, missense | |
| rs104886487 | untested, Glaucoma 1, open angle, F (GLC1F) [MIM:603383] | 151,176,198(-) | AGGGC(A/G)GCCTG | reference, missense | |
| rs104886488 | Pathogenic, Glaucoma 1, open angle, F (GLC1F) [MIM:603383] | 151,186,916(-) | CTCCC(A/G)CATCC | intron-variant, reference, missense | |
| rs104886491 | untested, Glaucoma 1, open angle, F (GLC1F) [MIM:603383] | 151,186,937(-) | GGCTG(A/G)GGACG | intron-variant, reference, missense |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv3695n106 | OTHER | inversion | 24896259 |
| nsv1067934 | OTHER | inversion | 25765185 |
| nsv1151906 | OTHER | inversion | 26484159 |
| nsv609034 | CNV | loss | 21841781 |
| nsv831188 | CNV | loss | 17160897 |
Residual Variation Intolerance Score:
98% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
10.51;
91.11% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ASB10 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ASB10 Gene
Disorders for ASB10 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| glaucoma 1, open angle, f |
|
|
| rieger syndrome, type 2 |
|
|
| iridogoniodysgenesis, type 2 |
|
|
| open-angle glaucoma |
|
|
| retinitis pigmentosa 10 |
|
|
Search ASB10 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
ASB10_HUMAN- Glaucoma 1, open angle, F (GLC1F) [MIM:603383]: A form of primary open angle glaucoma (POAG). POAG is characterized by a specific pattern of optic nerve and visual field defects. The angle of the anterior chamber of the eye is open, and usually the intraocular pressure is increased. However, glaucoma can occur at any intraocular pressure. The disease is generally asymptomatic until the late stages, by which time significant and irreversible optic nerve damage has already taken place. {ECO:0000269 PubMed:22156576}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for ASB10
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- ASB10
No data available for Genatlas for ASB10 Gene
Publications for ASB10 Gene
- Variants in ASB10 are associated with open-angle glaucoma. (PMID: 22156576) Pasutto F. … Wirtz M.K. (Hum. Mol. Genet. 2012) 2 3 4 64
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Variants in the ASB10 Gene Are Associated with Primary Open Angle Glaucoma. (PMID: 26713451) Micheal S. … den Hollander A.I. (PLoS ONE 2015) 3 64
- Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase. (PMID: 24337577) Andresen C.A. … Flores-Morales A. (J. Biol. Chem. 2014) 3 64
Products for ASB10 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ASB10
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for ASB10
- Search Origene for MassSpec and Protein Over-expression Lysates for ASB10
- Origene Custom Protein Services for ASB10
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ASB10
- Browse OriGene Inhibitory RNA Products For ASB10
- OriGene qPCR primer pairs for ASB10
- OriGene CRISPR knockouts for ASB10
- OriGene ORF clones in human for ASB10
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ASB10
- GenScript: Next-day shipping cDNA ORF clone for ASB10 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ASB10
- GenScript Custom Assay Services for ASB10
- GenScript Custom overexpressing Cell Line Services for ASB10
- GenScript: Design CRISPR guide RNA sequences for ASB10
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ASB10
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ASB10
- Novus Biologicals proteins for ASB10
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- antibodies-online Antibodies for ASB10: See all 25
- antibodies-online Kits for ASB10: See all 9
- antibodies-online Proteins for ASB10: See all 4
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for ASB10
- Search GeneTex for Proteins for ASB10
- ViGene Biosciences adenoviral particle packaged cDNA for ASB10 gene
- ViGene Biosciences lentiviral particle packaged cDNA for ASB10 gene
- ViGene Biosciences ready-to-package AAV shRNAs for ASB10 gene
- Search ViGene Biosciences for ASB10
- Santa Cruz Biotechnology (SCBT) Antibodies for ASB10
- Search Santa Cruz Biotechnology (SCBT) for ASB10 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ASB10
- Horizon Cell Lines for ASB10
- Cyagen custom Knockout/knockin (KOKI) mouse models for ASB10
- VectorBuilder custom plasmid, inducible vectors for ASB10
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ASB10
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ASB10 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer