Aliases for ASAH2B Gene
External Ids for ASAH2B Gene
Previous Symbols for ASAH2B Gene
GeneCards Summary for ASAH2B Gene
ASAH2B (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2B) is a Protein Coding gene. Among its related pathways are Sphingolipid metabolism and Sphingolipid metabolism. An important paralog of this gene is ASAH2.
Ceramidases (EC 18.104.22.168) are a group of enzymes which catalyze the hydrolysis of ceramides to produce sphingosine, which subsequently undergoes phosphorylation to generate sphingosine-1-phosphate (S1P). Ceramide and its downstream products, sphingosine and S1P, are bioactive lipids that mediate various cellular processes including cell growth arrest, differentiation and apoptosis.