ARTN Gene
protein-coding GIFtS : 60
GCID: GC01 P044398
artemin
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Aliasesfor ARTN gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Artemin 1 Neublastin3 EVN1 2 3 Neurotrophic Factor2 ENOVIN1 2 Enovin3 NBN1 2 Neublastin3
Export aliases for ARTN gene to outside databases Previous GC identifers: GC01P044237 GC01P043399 GC01P043828 GC01P043812 GC01P044068 GC01P044171 GC01P042517
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Summariesfor ARTN gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for ARTN : The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Oct 2008) UniProtKB/Swiss-Prot: ARTN_HUMAN, Q5T4W7 Function : Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex.Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue Gene Wiki entry for ARTN (Artemin)
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Genomic Viewsfor ARTN gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000001.10 NC_018912.1 NT_032977.9 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ARTN gene promoter: Egr-2 MZF-1 AP-4 ATF Other transcription factors Search SABiosciences Chromatin IP Primers for ARTN Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ARTN
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 1p33-p32 Ensembl cytogenetic band: 1p34.1 HGNC cytogenetic band: 1p33-p32 ARTN Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 1 GeneLoc Exon Structure
GeneLoc location for GC01P044398: view genomic region
(about GC identifiers )
Start:
44,398,992 bp from pter
End:
44,402,913 bp from pter
Size:
3,922 bases
Orientation:
plus strand
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Proteinsfor ARTN gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: ARTN_HUMAN, Q5T4W7 (See
protein sequence )Recommended Name: Artemin precursor Size : 220 amino acids; 22878 Da
Subunit : Homodimer; disulfide-linked. Binds to RET (By similarity)
Subcellular location : Secreted (By similarity)
Developmental stage : Expressed during embryogenesis. High level expression seen in fetal kidney and lung while a lowlevel expression seen in the fetal brain
4 PDB 3D structures from and Proteopedia for ARTN :2ASK (3D)
  2GH0 (3D)
  2GYR (3D)
  2GYZ (3D)
 
Secondary accessions : D3DPY1 D3DPY3 O95441 O96030 Q6P6A3Alternative splicing : 3 isoforms : Q5T4W7-1 Q5T4W7-2 Q5T4W7-3 Explore the universe of human proteins at neXtProt for ARTN: NX_Q5T4W7 ARTN Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (3 alternative transcripts):
NP_001129687.1 NP_476431.2 NP_476432.2 ENSEMBL proteins: ENSP00000361434 ENSP00000434784 ENSP00000435804 ENSP00000436727 ENSP00000436149 ENSP00000434071 ENSP00000435140 ENSP00000434856 ENSP00000361429 ENSP00000391998 ENSP00000387435 Reactome Protein details: Q5T4W7 Human Recombinant Protein Products for ARTN: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005576 extracellular region
-- -- GO:0005615 extracellular space
IEA --
ARTN for ontologies About GeneDecksing ARTN Antibody Products: Assay Products for ARTN:
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Protein
Domains / Familiesfor ARTN gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
ARTN for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q5T4W7 ProtoNet protein and cluster: Q5T4W7
2 Blocks protein families : IPB001839 Transforming growth factor beta (TGFb) IPB002400 Growth factor cystine knot superfamily signature UniProtKB/Swiss-Prot: ARTN_HUMAN, Q5T4W7 Similarity : Belongs to the TGF-beta family. GDNF subfamily
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Functionfor ARTN gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: ARTN_HUMAN, Q5T4W7 Function : Ligand for the GFR-alpha-3-RET receptor complex but can also activate the GFR-alpha-1-RET receptor complex.Supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view) : About this table
ARTN for ontologies About GeneDecksing Phenotypes: 2 GenomeRNAi human phenotypes for ARTN : 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Artn) :
ARTN for phenotypes About GeneDecksing Animal Models: Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ARTN (see all 5 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ARTN (see all 6 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): ARTN (NM_057090 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARTN Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ARTN
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARTN
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Pathways & Interactionsfor ARTN gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Unified GeneCards pathways   About this table See pathways by source Super-pathway contained gene-specific pathways 1 Development EGFR signaling pathway 2 NCAM signaling for neurite out-growth 3 Axon guidance
Pathway sources See GeneCards unified pathways Show all pathways 1 EMD Millipore Pathway for ARTN 1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ARTN 1 GeneGo (Thomson Reuters) Pathway for ARTN 4
Reactome Pathways for ARTN
ARTN for pathways About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARTN STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)5/67 Interacting proteins for ARTN (Q5T4W7 3 ENSP00000391998 4 ) via UniProtKB, MINT, STRING , and/or I2D (see all 67 )About this table Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7 ): About this table
ARTN for ontologies About GeneDecksing
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Drugs & Compoundsfor ARTN gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section
ARTN for compounds About GeneDecksing Browse Tocris compounds for ARTN 4 Novoseek chemical compound relationships for ARTN gene About this table
Search CenterWatch for drugs/clinical trials and news about ARTN
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Transcriptsfor ARTN gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for ARTN gene (5 alternative transcripts): NM_001136215.1 NM_057090.2 NM_057091.2 NM_003976.3 NM_057160.2 Unigene Cluster for ARTN:
Artemin Hs.632404 [show with all ESTs ] Unigene Representative Sequence: NM_057090 11 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000372359 (uc001cks.3 ) ENST00000477048 ENST00000471394 ENST00000498139 (uc001cku.3 uc001ckw.3 )ENST00000491846 ENST00000479128 ENST00000472435 ENST00000474592 ENST00000372354 ENST00000438616 ENST00000414809 (uc001ckv.3 uc001ckt.3 ) Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ARTN (see all 5 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ARTN (see all 6 )OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 3 ): ARTN (NM_057090 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARTN Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ARTN
Additional cDNA sequence: AF109401.1 AF120274.1 BC062375.1
6 DOTS entries : DT.101980137 DT.40216700
DT.91699435 DT.95158250 DT.40233398 DT.75101766 24/38 AceView cDNA sequences (see all 38 ):
AW137020 BF063378 BC062375 AI935302 AF109401 AW203993 NM_057160 BM981370 AF120274 NM_003976 BP353368 NM_057090 AI768514 BQ129389 AW206576 AI225050 AI695822 AW207099 BQ129248 AW293171 AW134909 BF507803 AI424604 AW138964 GeneLoc Exon Structure 4 Alternative Splicing Database (ASD) splice patterns (SP) for ARTN About this scheme ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b SP1 :         -   -     -     SP2 :       -   -   -         SP3 :                   SP4 :               -    
ECgene alternative splicing isoforms for ARTN
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Expression for ARTN gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section ARTN expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: GGAGCTGGCCAbout this image ARTN expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table
See ARTN Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ARTN SOURCE GeneReport for Unigene cluster: Hs.632404 UniProtKB/Swiss-Prot: ARTN_HUMAN, Q5T4W7 Tissue specificity : Ubiquitous. Expressed at high levels in peripheral tissues including prostate, placenta, pancreas,heart, kidney, pituitary gland, lung and testis. Expressed at low levels in the brain SABiosciences Expression via Pathway-Focused PCR Arrays including ARTN : Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ARTNBrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat ARTN QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ARTN QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ARTN In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARTN
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Orthologsfor ARTN gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for ARTN gene from 3/9 species (see all 9 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
LOC1008579101
uncharacterized LOC100857910
54.27(n) 46.38(a)
 
100857910 XM_003641685.1 XP_003641733.1
lizard (Anolis carolinensis)
Reptilia
ARTN6
--
48(a)
1 ↔ 1
4(108783127-108783909)
zebrafish (Danio rerio)
Actinopterygii
si:ch1073-141i10.16
si:ch1073-141i10.1
45(a)
1 → many
6(3266343-3266657)
ENSEMBL Gene Tree for ARTN (if available)TreeFam Gene Tree for ARTN (if available)
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Paralogsfor ARTN gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for ARTN gene GDNF 2 PSPN 2 NRTN 2 1 SIMAP similar gene for ARTN using alignment to 5 protein entries: ARTN_HUMAN (see all proteins ):PSPN
ARTN for paralogs About GeneDecksing
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Genomic Variantsfor ARTN gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 1 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for ARTN (44398992 - 44402913 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for ARTN: --
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ARTN
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Disorders
/ Diseasesfor ARTN gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Novoseek ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
ARTN for disorders About GeneDecksing
OMIM gene information: 603886
OMIM disorders : --19 diseases for ARTN : About MalaCards neurodegenerative disease spinal cord injury burning mouth syndrome neuronitis hirschsprung's disease parkinson's disease pancreatic cancer endometrial carcinoma pancreatitis esophageal carcinoma thyroid carcinoma carcinoma esophagitis pancreatic carcinoma lung carcinoma neuropathy thyroiditis adenocarcinoma prostatitis 1 disease from the University of Copenhagen DISEASES database for ARTN :Hirschsprung's disease 6 Novoseek disease relationships for ARTN gene About this table
Human Genome Epidemiology (HuGE) Navigator: ARTN (1 document)Export disorders for ARTN gene to outside databases
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Publicationsfor ARTN gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for ARTN gene, integrated from 9 sources (see all 67 ): (articles sorted by number of sources associating them with ARTN) Utopia : connect your pdf to the dynamic world of online information
Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex. (PubMed id 9883723) 1 , 2 , 3, 9 Baloh R.H....Milbrandt J. (1998) Enovin, a member of the glial cell-line-derived neurotrophic factor (GDNF) family with growth promoting activity on neuronal cells. Existence and tissue-specific expression of different splice variants. (PubMed id 10583383) 1 , 2 , 9 Masure S.... Gordon R.D. (1999) Structure of artemin complexed with its receptor GFRalpha3: convergent recognition of glial cell line-derived neurotrophic factors. (PubMed id 16765900) 1 , 2 , 9 Wang X.... Garcia K.C. (2006) In vivo protection of nigral dopamine neurons by lentiviral gene transfer of the novel GDNF-family member neublastin/artemin. (PubMed id 10673327) 1 , 2 , 9 Rosenblad C....Johansen T.E. (2000) The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414) 1 , 2 Gregory S.G.... Bentley D.R. (2006) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 Gerhard D.S....Malek J. (2004) Artemin is estrogen regulated and mediates antiestrog en resistance in mammary carcinoma. (PubMed id 20305694) 1 , 9 Kang J....Lobie P.E. (2010) Artemin stimulates oncogenicity and invasiveness of h uman endometrial carcinoma cells. (PubMed id 20118197) 1 , 9 Pandey V....Lobie P.E. (2010) Artemin is oncogenic for human mammary carcinoma cells. (PubMed id 19363524) 1 , 9 Kang J....Lobie P.E. (2009) [Artemin and GFRalpha3 expressions and their relevance to perineural invasiveness and metastasis of pancreatic carcinoma.] (PubMed id 19304517) 1 , 9 Zhu D.L....Gao J.M. (2009)
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External Searches for ARTN gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing ARTN gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
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Other Databases showing ARTN gene
(According to HUGE )
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Specialized Databases showing ARTN gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for ARTN Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for ARTN gene: Search GeneIP for patents involving ARTN GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor ARTN gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
OriGene Antibodies for ARTN OriGene shRNA RFP for ARTN OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for ARTN OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for ARTN OriGene Protein Over-expression Lysate for ARTN Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for ARTN OriGene 3'-UTR Clone for ARTN OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for ARTN OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for ARTN Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for ARTN OriGene Custom Protein Services for ARTN OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARTN QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing ARTN QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat ARTN QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat ARTN QIAGEN QuantiFast Probe-based Assays in human , mouse , rat ARTN QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat ARTN
Search Tocris compounds for ARTN
Recombinant Protein for ARTN
ARTN Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARTN
ThermoFisher Antibodies for ARTN
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat ARTN
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