Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ART5 Gene

protein-coding GIFtS: 50
GCID: GC11M003659

ADP-ribosyltransferase 5

Search for ART5
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
ADP-Ribosyltransferase 5¹ ²		NAD(P)(+)--Arginine ADP-Ribosyltransferase 5² ³
Mono(ADP-Ribosyl)Transferase 5² ³		EC 2.4.2.31³ ⁸
ARTC5² ³		Ecto-ADP-Ribosyltransferase 5²
ADP-Ribosyltransferase C2 And C3 Toxin-Like 5² ³

External Ids:	HGNC: 24049¹	Entrez Gene: 116969²	Ensembl: ENSG00000167311⁷	OMIM: 610625⁵	UniProtKB: Q96L15³

Export aliases for ART5 gene to outside databases

Previous GC identifers: GC11M004234 GC11M003929 GC11M003621 GC11M003624 GC11M003616 GC11M003397

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ART5:

The protein encoded by this gene belongs to the ARG-specific ADP-ribosyltransferase family. Proteins in this family

regulate the function of target proteins by attaching ADP-ribose to specific amino acid residues in their target

proteins. The mouse homolog lacks a glycosylphosphatidylinositol-anchor signal sequence and is predicted to be a

secretory enzyme. Transcript variants with different 5' UTRs, but encoding the same protein have been found for this

gene. (provided by RefSeq, Jul 2008)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_009237.18

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ART5 gene promoter:
E2F-4 E2F-3a E2F-1 FOXF2 E2F E2F-2
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ART5 promoter sequence

Search SABiosciences Chromatin IP Primers for ART5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ART5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4 Ensembl cytogenetic band: 11p15.4 HGNC cytogenetic band: 11p15.4

ART5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ART5 gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M003659: view genomic region (about GC identifiers)

Start:	3,659,733 bp from pter	End:	3,663,546 bp from pter
Size:	3,814 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: NAR5_HUMAN, Q96L15 (See protein sequence)

Recommended Name: Ecto-ADP-ribosyltransferase 5 precursor

Size: 291 amino acids; 32054 Da

Subcellular location: Secreted (Potential)

Secondary accessions: C9IYG7 Q6UX84 Q86W02

Alternative splicing: 2 isoforms: Q96L15-1 Q96L15-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ART5: NX_Q96L15

2 DME Specific Peptides for ART5 (Q96L15)

EEMEEKA

CSHFNCAYLG

ART5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001073004.1 NP_443750.2

ENSEMBL proteins:

ENSP00000380258 ENSP00000380257 ENSP00000352992 ENSP00000402737 ENSP00000413852

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: ART5 OriGene Protein Over-expression Lysate: ART5 OriGene Custom Protein Services for ART5
	GenScript Custom Purified and Recombinant Proteins Services for ART5
	Novus Biologicals ART5 Protein Novus Biologicals ART5 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for ART5

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005576	extracellular region	IEA	--
GO:0005624	membrane fraction	--	--
GO:0016020	membrane	IEA	--

ART5 for ontologies About GeneDecksing

ART5 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for ART5
	GenScript Custom Superior Antibodies Services for ART5
	Novus Biologicals ART5 Antibodies
	Search for Antibodies for ART5 at Abcam
	Uscn Antibodies for ART5
	ThermoFisher Antibodies for ART5

Assay Products for ART5:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ART5
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ART5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ART5 for domains About GeneDecksing

1 InterPro domain/family:

IPR000768 ART

Graphical View of Domain Structure for InterPro Entry Q96L15

ProtoNet protein and cluster: Q96L15

1 Blocks protein family: IPB000768 NAD:arginine ADP-ribosyltransferase

UniProtKB/Swiss-Prot: NAR5_HUMAN, Q96L15

Similarity: Belongs to the Arg-specific ADP-ribosyltransferase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: NAR5_HUMAN, Q96L15

Catalytic activity: NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine

Catalytic activity: NADP(+) + protein-L-arginine = nicotinamide +

N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine

Enzyme Number (IUBMB): EC 2.4.2.31¹ ²

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ART5
		1 QIAGEN miScript miRNA Assays for microRNA that regulate ART5:
		hsa-miR-3175
		SwitchGear 3'UTR luciferase reporter plasmid: ART5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ART5 (see all 7) OriGene shRNA RFP: ART5 OriGene siRNA: ART5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ART5

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for ART5

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ART5 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ART5 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): ART5 (NM_001079536)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ART5
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART5

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ART5
		Search LifeMap BioReagents cell lines for ART5

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART5

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003950	NAD+ ADP-ribosyltransferase activity	IEA	--
GO:0003953	NAD+ nucleosidase activity	IEA	--
GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity	IEA	--

ART5 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for ART5:

Increased gamma-H2AX phosphory

Synthetic lethal with Ras

Animal Models:
1 MGI phenotypic allele

for Art5 (no phenotypes)

ART5 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

NAD metabolism

NAD metabolism

1.00

NAD metabolism

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 EMD Millipore Pathway for ART5

NAD metabolism

1 GeneGo (Thomson Reuters) Pathway for ART5

NAD metabolism

ART5 for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for ART5

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006471	protein ADP-ribosylation	IEA	--

ART5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ART5

5 HMDB Compounds for ART5 About this table

Compound	Synonyms	CAS #	PubMed Ids
L-Arginine	(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoate (see all 14)	74-79-3	--
NAD	3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)	53-84-9	--
NADH	1,4-Dihydronicotinamide adenine dinucleotide (see all 17)	58-68-4	--
NADP	Adenine-nicotinamide dinucleotide phosphate (see all 18)	53-59-8	--
Niacinamide	3-Carbamoylpyridine (see all 77)	98-92-0	--

Search CenterWatch for drugs/clinical trials and news about ART5 / NAR5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ART5 gene (2 alternative transcripts):

NM_001079536.1 NM_053017.3

Unigene Cluster for ART5:

ADP-ribosyltransferase 5

Hs.125680 [show with all ESTs]

Unigene Representative Sequence: NM_053017

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000397068(uc001lyb.1 uc001lyd.3 uc009yea.3) ENST00000397067

ENST00000359918(uc001lyc.1) ENST00000453353 ENST00000425767

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ART5
		1 QIAGEN miScript miRNA Assays for microRNA that regulate ART5:
		hsa-miR-3175
		SwitchGear 3'UTR luciferase reporter plasmid: ART5 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ART5 (see all 7) OriGene shRNA RFP: ART5 OriGene siRNA: ART5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ART5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ART5 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ART5 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): ART5 (NM_001079536)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ART5
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ART5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ART5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ART5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ART5

Additional cDNA sequence:

AK313531.1 AY358466.1 BC014577.1 Y16835.1

4 DOTS entries:

DT.103375 DT.95361634 DT.95245553 DT.97820297

15 AceView cDNA sequences:

NM_053017 BM728297 CD557970 AY358466 AW241897 AA884778 BC014577 BI496399

BM559379 F23199 BI496400 BQ218251 BI561989 BF126069 BI825352

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for ART5 About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3
SP1:
SP2:							-

ECgene alternative splicing isoforms for ART5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ART5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

ART5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

4 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Limb

Zeugopod

Mesenchymal Condensate Cells

Bone, Cartilage

Skeletal Muscle

Trunk Muscles

Skeletal Muscle

Somite

Lumbar Hypaxial Myotome

Somite

Thoracic Hypaxial Myotome

Somite

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ART5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ART5

SOURCE GeneReport for Unigene cluster: Hs.125680

SABiosciences Custom PCR Arrays for ART5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ART5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ART5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ART5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ART5

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ART5 gene from 2/8 species (see all 8) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ART5¹	ADP-ribosyltransferase 5	60.97(n) 50.25(a)		430227 XM_427780.3 XP_427780.3
zebrafish (Danio rerio)	Actinopterygii	CABZ01019905.1⁶ CABZ01019905.2⁶ (see all 14)	--	35(a) 35(a) (see all 14)	many ↔ many many ↔ many (see all 14)	3(7938826-7939488) 3(7909035-7909774)

ENSEMBL Gene Tree for ART5 (if available)
TreeFam Gene Tree for ART5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ART5 gene

ART4² ART1² ART3²

4 SIMAP similar genes for ART5 using alignment to 3 protein entries: NAR5_HUMAN (see all proteins):

ART3 ART1 ART4 DO

ART5 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for ART5
PGOHUM00000242793

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11028690^1,2	C,F,H,	--	3659292(+)	`TACACA/GGGTCT`	2	--	ds500¹		17		NS EA NA WA CSA	932
rs115768252^1,2	F,	--	3659309(+)	`GAGACC/TGTGTT`	2	--	ds500¹		1		WA	118
rs7940005^1,2	C,F,A,	--	3659354(+)	`TGAGAT/CGGAGT`	2	--	ds500¹		4		WA CSA	6
rs7929372^1,2	C,F,A,	--	3659367(+)	`TGCTCT/AGTCGC`	2	--	ds500¹		6		NA WA CSA	10
rs12275350^1,2	A,	--	3659370(+)	`tctgtC/Tgccca`	2	--	ds500¹		1		NA	2
rs7929470^1,2	C,F,A,	--	3659408(+)	`CTCATT/GGCAAG`	2	--	ds500¹		5		NA WA CSA	9
rs112649516^1,2		--	3659465(+)	`TAGCTG/AGGACT`	2	--	ds500¹		1		CSA	2
rs7939282^1,2	C,F,A,	--	3659481(+)	`TGCCCG/TCCACC`	2	--	ds500¹		4		NA WA CSA	7
rs182929924^1,2		--	3659489(+)	`ACCACA/GCTCGG`	2	--	ds500¹		0	--	--	--	--
rs7929582^1,2	C,F,A,	--	3659491(+)	`CACGCT/CCGGCT`	2	--	ds500¹		4		NA WA CSA	7

HapMap Linkage Disequilibrium report for ART5 (3659733 - 3663546 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for ART5
3 CNVs: 3833 31799 71243

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ART5

DNA2.0 Custom Variant and Variant Library Synthesis for ART5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ART5 for disorders About MalaCards

ART5 for disorders About GeneDecksing

OMIM gene information: 610625 OMIM disorders: --

Export disorders for ART5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ART5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ART5)

Utopia: connect your pdf to the dynamic
world of online information

Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5. (PubMed id 11587854)^{1, 3, 9} Glowacki G....Koch-Nolte F. (2001)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse. (PubMed id 12070318)^{1, 2} Glowacki G....Koch-Nolte F. (2002)
Characterization of glycosylphosphatidylinositiol-anchored, secreted, and intracellular vertebrate mono-ADP-ribosyltransferases. (PubMed id 10448534)^{1, 3} Okazaki I.J. and Moss J. (1999)
Toward a unified nomenclature for mammalian ADP- ribosyltransferases. (PubMed id 20106667)² Hottiger M.O.... Koch-Nolte F. (2010)
hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)¹ Lamesch P.... Vidal M. (2007)
Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)² Taylor T.D....Sakaki Y. (2006)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Expression and selective up-regulation of toxin-related mono ADP-ribosyltransferases by pathogen-associated molecular patterns in alveolar epithelial cells. (PubMed id 17707376)⁹ Balducci E....Rappuoli R. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 116969	HGNC: 24049	AceView: ART5	Ensembl:ENSG00000167311	euGenes: HUgn116969
ECgene: ART5	H-InvDB: ART5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ART5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for ART5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ART5 gene:
Search GeneIP for patents involving ART5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for ART5
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ART5		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ART5
	OriGene Protein Over-expression Lysate for ART5		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for ART5		Browse 3'-UTR reporter clones for miRNA target validation
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ART5		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ART5
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for ART5		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for ART5		OriGene Custom Protein Services for ART5
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ART5
	Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ART5
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ART5
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ART5
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ART5
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ART5

	GenScript Custom Purified and Recombinant Proteins Services for ART5		GenScript cDNA clones with any tag delivered in your preferred vector for ART5
	GenScript Custom Assay Services for ART5		GenScript Custom Superior Antibodies Services for ART5
	GenScript Custom overexpressing Cell Line Services for ART5		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in ART5 promoter
	Search Chromatin IP Primers for ART5
	RT² qPCR Primer Assay in human, mouse, rat ART5
	Search GNC Networks for ART5
	SABiosciences Custom PCR Arrays for ART5

Search Tocris compounds for ART5

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	ART5 antibodies
	ART5 proteins
	ART5 lysates

	Search for Antibodies for ART5 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for ART5
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

ART5 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for ART5

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART5

	SwitchGear 3'UTR luciferase reporter plasmids for ART5
	SwitchGear Promoter luciferase reporter plasmids for ART5

ThermoFisher Antibodies for ART5

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART5

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ART5 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

ART5 Gene

ADP-ribosyltransferase 5

Aliases
for ART5 gene

Summaries
for ART5 gene

Genomic Views
for ART5 gene

Proteins
for ART5 gene

Protein Domains /
Families
for ART5 gene

Function
for ART5 gene

Pathways & Interactions
for ART5 gene

Drugs & Compounds
for ART5 gene

Transcripts
for ART5 gene

Expression
for ART5 gene

Orthologs
for ART5 gene

Paralogs
for ART5 gene

Genomic Variants
for ART5 gene

Disorders / Diseases
for ART5 gene

Publications
for ART5 gene

External Searches for ART5 gene

Genome Databases showing ART5 gene

Other Databases showing ART5 gene

Specialized Databases showing ART5 gene

Intellectual Property
for ART5 gene

Products
for ART5 gene

View Random Gene

Advanced Search

Export list of displayed genes

ART5 Gene

ADP-ribosyltransferase 5

Aliasesfor ART5 gene

Summariesfor ART5 gene

Genomic Viewsfor ART5 gene

Proteinsfor ART5 gene

Protein Domains /Familiesfor ART5 gene

Functionfor ART5 gene

Pathways & Interactionsfor ART5 gene

Drugs & Compoundsfor ART5 gene

Transcriptsfor ART5 gene

Expression for ART5 gene

Orthologsfor ART5 gene

Paralogsfor ART5 gene

Genomic Variantsfor ART5 gene

Disorders / Diseasesfor ART5 gene

Publicationsfor ART5 gene

External Searches for ART5 gene

Genome Databases showing ART5 gene

Other Databases showing ART5 gene

Specialized Databases showing ART5 gene

Intellectual Propertyfor ART5 gene

Productsfor ART5 gene

View Random Gene

Aliases
for ART5 gene

Summaries
for ART5 gene

Genomic Views
for ART5 gene

Proteins
for ART5 gene

Protein Domains /
Families
for ART5 gene

Function
for ART5 gene

Pathways & Interactions
for ART5 gene

Drugs & Compounds
for ART5 gene

Transcripts
for ART5 gene

Expression
for ART5 gene

Orthologs
for ART5 gene

Paralogs
for ART5 gene

Genomic Variants
for ART5 gene

Disorders / Diseases
for ART5 gene

Publications
for ART5 gene

Intellectual Property
for ART5 gene

Products
for ART5 gene