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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ART5 Gene

protein-coding   GIFtS: 50
GCID: GC11M003659

ADP-Ribosyltransferase 5

  Search for ART5
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ADP-Ribosyltransferase 51 2     NAD(P)(+)--Arginine ADP-Ribosyltransferase 52 3
Mono(ADP-Ribosyl)Transferase 52 3     EC 2.4.2.313 8
ARTC52 3     Ecto-ADP-Ribosyltransferase 52
ADP-Ribosyltransferase C2 And C3 Toxin-Like 52 3     

External Ids:    HGNC: 240491   Entrez Gene: 1169692   Ensembl: ENSG000001673117   OMIM: 6106255   UniProtKB: Q96L153   

Export aliases for ART5 gene to outside databases

Previous GC identifers: GC11M004234 GC11M003929 GC11M003621 GC11M003624 GC11M003616 GC11M003397


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ART5 Gene:
The protein encoded by this gene belongs to the ARG-specific ADP-ribosyltransferase family. Proteins in this
family regulate the function of target proteins by attaching ADP-ribose to specific amino acid residues in their
target proteins. The mouse homolog lacks a glycosylphosphatidylinositol-anchor signal sequence and is predicted
to be a secretory enzyme. Transcript variants with different 5' UTRs, but encoding the same protein have been
found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for ART5 Gene: 
ART5 (ADP-ribosyltransferase 5) is a protein-coding gene. Among its related super-pathways are Nicotinate and nicotinamide metabolism. GO annotations related to this gene include NAD+ ADP-ribosyltransferase activity and NAD+ nucleosidase activity. An important paralog of this gene is ART4.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NT_009237.18  NC_018922.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ART5 gene promoter:
         E2F-4   E2F-3a   E2F-1   FOXF2   E2F   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidART5 promoter sequence
   Search SABiosciences Chromatin IP Primers for ART5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ART5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.4

ART5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ART5 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M003659:  view genomic region     (about GC identifiers)

Start:
3,659,733 bp from pter      End:
3,663,546 bp from pter
Size:
3,814 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: NAR5_HUMAN, Q96L15 (See protein sequence)
Recommended Name: Ecto-ADP-ribosyltransferase 5 precursor  
Size: 291 amino acids; 32054 Da
Subcellular location: Secreted (Potential)
Secondary accessions: C9IYG7 Q6UX84 Q86W02
Alternative splicing: 2 isoforms:  Q96L15-1   Q96L15-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ART5: NX_Q96L15

Explore proteomics data for ART5 at MOPED 

2 DME Specific Peptides for ART5 (Q96L15)
 EEMEEKA  CSHFNCAYLG 

ART5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

ART5 Protein Expression
REFSEQ proteins (2 alternative transcripts): 
NP_001073004.1  NP_443750.2  

ENSEMBL proteins: 
 ENSP00000380258   ENSP00000380257   ENSP00000352992   ENSP00000402737   ENSP00000413852  

Human Recombinant Protein Products for ART5: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for ART5
OriGene Protein Over-expression Lysate for ART5
OriGene MassSpec for ART5 
OriGene Custom Protein Services for ART5
GenScript Custom Purified and Recombinant Proteins Services for ART5
Novus Biologicals ART5 Protein
Novus Biologicals ART5 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for ART5 

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region IEA--
GO:0016020membrane IEA--

ART5 for ontologies           About GeneDecksing



ART5 Antibody Products: 
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Novus Biologicals ART5 Antibodies
Abcam antibodies for ART5
Cloud-Clone Corp. Antibodies for ART5 
ThermoFisher Antibodies for ART5
LSBio Antibodies in human, mouse, rat for ART5 

Assay Products for ART5: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for ART5
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for ART5
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for ART5 
Cloud-Clone Corp. CLIAs for ART5


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
1 InterPro protein domain:
 IPR000768 ART

Graphical View of Domain Structure for InterPro Entry Q96L15

ProtoNet protein and cluster: Q96L15

1 Blocks protein domain: IPB000768 NAD:arginine ADP-ribosyltransferase

UniProtKB/Swiss-Prot: NAR5_HUMAN, Q96L15
Similarity: Belongs to the Arg-specific ADP-ribosyltransferase family


ART5 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: NAR5_HUMAN, Q96L15
Catalytic activity: NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine
Catalytic activity: NADP(+) + protein-L-arginine = nicotinamide +
N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine

     Enzyme Number (IUBMB): EC 2.4.2.311 2

     Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003950NAD+ ADP-ribosyltransferase activity IEA--
GO:0003953NAD+ nucleosidase activity IEA--
GO:0003956NAD(P)+-protein-arginine ADP-ribosyltransferase activity IEA--
     
ART5 for ontologies           About GeneDecksing


Phenotypes:
     2 GenomeRNAi human phenotypes for ART5:
 Increased gamma-H2AX phosphory  Synthetic lethal with Ras 

     1 MGI phenotypic allele for Art5 (no phenotypes)

ART5 for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for ART5 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ART5

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ART5 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ART5 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ART5
1 QIAGEN miScript miRNA Assays for microRNA that regulate ART5:
hsa-miR-3175
SwitchGear 3'UTR luciferase reporter plasmidART5 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for ART5
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ART5

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for ART5
Sirion Biotech Customized adenovirus for overexpression of ART5

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for ART5 (see all 11)
OriGene ORF clones in mouse, rat for ART5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): ART5 (NM_001079536)
Sino Biological Human cDNA Clone for ART5
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ART5
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART5
Sirion Biotech Customized lentivirus for stable overexpression of ART5 
                     Customized lentivirus expression plasmids for stable overexpression of ART5 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for ART5
Search LifeMap BioReagents cell lines for ART5
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART5


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for ART5 About                                                                                                See pathways by source

SuperPathContained pathways About
1NAD metabolism
NAD metabolism0.43

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 EMD Millipore Pathway for ART5
    NAD metabolism


1 GeneGo (Thomson Reuters) Pathway for ART5
    NAD metabolism




ART5 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ART5

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006471protein ADP-ribosylation IEA--

ART5 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ART5 (NAR5)

5 HMDB Compounds for ART5    About this table
CompoundSynonyms CAS #PubMed Ids
L-Arginine(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoate (see all 14)74-79-3--
NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--
Niacinamide3-Carbamoylpyridine (see all 77)98-92-0--

Search CenterWatch for drugs/clinical trials and news about ART5 / NAR5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ART5 gene (2 alternative transcripts): 
NM_001079536.1  NM_053017.3  

Unigene Cluster for ART5:

ADP-ribosyltransferase 5
Hs.125680  [show with all ESTs]
Unigene Representative Sequence: NM_053017
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000397068(uc001lyb.1 uc001lyd.3 uc009yea.3) ENST00000397067
ENST00000359918(uc001lyc.1) ENST00000453353 ENST00000425767
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ART5
1 QIAGEN miScript miRNA Assays for microRNA that regulate ART5:
hsa-miR-3175
SwitchGear 3'UTR luciferase reporter plasmidART5 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for ART5
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ART5
Clone
Products:
     
OriGene clones in human, mouse for ART5 (see all 11)
OriGene ORF clones in mouse, rat for ART5
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): ART5 (NM_001079536)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ART5
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART5
Sirion Biotech Customized lentivirus for stable overexpression of ART5 
                     Customized lentivirus expression plasmids for stable overexpression of ART5 
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for ART5
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ART5
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ART5
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ART5

Additional mRNA sequence: 

AK313531.1 AY358466.1 BC014577.1 Y16835.1 

4 DOTS entries:

DT.103375  DT.95361634  DT.95245553  DT.97820297 

15 AceView cDNA sequences:

NM_053017 BM728297 BC014577 F23199 CD557970 AW241897 BM559379 AY358466 
AA884778 BI496399 BI496400 BQ218251 BI561989 BF126069 BI825352 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for ART5    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3
SP1:                              
SP2:                    -         


ECgene alternative splicing isoforms for ART5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ART5 expression in normal human tissues (normalized intensities)      ART5 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
ART5 Expression
About this image


ART5 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/13 selected tissues (see all 13) fully expand
 
 Limb (Muscoskeletal System)    fully expand to see all 4 entries
         Mesenchymal Condensate Cells Zeugopod
         limb/hindlimb   
 
 Skeletal Muscle (Muscoskeletal System)    fully expand to see all 4 entries
         Trunk Muscles
         cavities and their linings/intraembryonic coelom/diaphragm   
 
 Bone (Muscoskeletal System)    fully expand to see all 2 entries
         Mesenchymal Condensate Cells Zeugopod
         Zeugopod Periosteum
 
 Heart (Cardiovascular System)    fully expand to see all 2 entries
         heart/ventricle   
 
 Nose (Sensory Organs)    fully expand to see all 2 entries
         sensory organ/nose/nasal cavity   

See ART5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ART5

SOURCE GeneReport for Unigene cluster: Hs.125680
    SABiosciences Custom PCR Arrays for ART5
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for ART5
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ART5
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ART5
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ART5
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART5

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for ART5 gene from 4/10 species (see all 10)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Art51 , 5 ADP-ribosyltransferase 51, 5 84.19(n)1
83.82(a)1
  7 (54.71 cM)5
118751  NM_007491.21  NP_031517.21 
 1020968795 
chicken
(Gallus gallus)
Aves ART51 ADP-ribosyltransferase 5 60.97(n)
50.25(a)
  430227  XM_427780.3  XP_427780.3 
lizard
(Anolis carolinensis)
Reptilia --
Uncharacterized protein
28(a)
possible ortholog
GL343253.1(1869726-1875280)
zebrafish
(Danio rerio)
Actinopterygii CABZ01019905.16
CR846080.56
(see all 15)
Uncharacterized protein
(see all 15)
34(a)
33(a)
(see all 15)
many ↔ many
many ↔ many
(see all 15)
3(7938826-7939488)
3(10193161-10193877)


ENSEMBL Gene Tree for ART5 (if available)
TreeFam Gene Tree for ART5 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for ART5 gene
ART42  ART12  ART32  
4 SIMAP similar genes for ART5 using alignment to 3 protein entries:     NAR5_HUMAN (see all proteins):
ART3    ART1    ART4    DO

ART5 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for ART5
PGOHUM00000242793


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/216 SNPs in ART5 are shown (see all 216)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 11 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs110286901,2
C,F,H--3659292(+) TACACA/GGGTCT 2 -- ds500117Minor allele frequency- G:0.30NS EA NA WA CSA 932
rs1157682521,2
C,F--3659309(+) GAGACC/TGTGTT 2 -- ds50011Minor allele frequency- T:0.03WA 118
rs79400051,2
C,F,A--3659354(+) TGAGAT/CGGAGT 2 -- ds50014Minor allele frequency- C:0.33WA CSA 6
rs79293721,2
C,F,A--3659367(+) TGCTCT/AGTCGC 2 -- ds50016Minor allele frequency- A:0.40NA WA CSA 10
rs122753501,2
C,F,A--3659370(+) tctgtC/Tgccca 2 -- ds50011Minor allele frequency- T:0.00NA 2
rs79294701,2
C,F,A--3659408(+) CTCATT/GGCAAG 2 -- ds50015Minor allele frequency- G:0.33NA WA CSA 9
rs1126495161,2
C,F--3659465(+) TAGCTG/AGGACT 2 -- ds50011Minor allele frequency- A:0.50CSA 2
rs79392821,2
C,F,A--3659481(+) TGCCCG/TCCACC 2 -- ds50014Minor allele frequency- T:0.29NA WA CSA 7
rs1829299241,2
--3659489(+) ACCACA/GCTCGG 2 -- ds50010--------
rs79295821,2
C,F,A--3659491(+) CACGCT/CCGGCT 2 -- ds50014Minor allele frequency- C:0.29NA WA CSA 7

HapMap Linkage Disequilibrium report for ART5 (3659733 - 3663546 bp)

Structural Variations
     Database of Genomic Variants (DGV) 10/12 variations for ART5 (see all 12):    About this table     
Variant IDTypeSubtypePubMed ID
esv2658889CNV Deletion23128226
nsv509385CNV Insertion20534489
nsv428247CNV Loss18775914
nsv832052CNV Loss17160897
nsv8775CNV Loss18304495
nsv526441CNV Gain19592680
nsv467660CNV Gain19166990
nsv832051CNV Gain17160897
esv28322CNV Gain+Loss19812545
essv2992CNV CNV17122850

SABiosciences Cancer Mutation PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing ART5
DNA2.0 Custom Variant and Variant Library Synthesis for ART5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ART5 for disorders           About MalaCards
OMIM gene information: 610625    OMIM disorders: --


ART5 for disorders           About GeneDecksing


Export disorders for ART5 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for ART5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ART5)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5. (PubMed id 11587854)1, 3, 9 Glowacki G....Koch-Nolte F. (2001)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
  4. The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse. (PubMed id 12070318)1, 2 Glowacki G....Koch-Nolte F. (2002)
  5. Characterization of glycosylphosphatidylinositiol-anchored, secreted, and intracellular vertebrate mono-ADP-ribosyltransferases. (PubMed id 10448534)1, 3 Okazaki I.J. and Moss J. (1999)
  6. Toward a unified nomenclature for mammalian ADP- ribosyltransferases. (PubMed id 20106667)2 Hottiger M.O.... Koch-Nolte F. (2010)
  7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  8. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  10. Expression and selective up-regulation of toxin-related mono ADP-ribosyltransferases by pathogen-associated molecular patterns in alveolar epithelial cells. (PubMed id 17707376)9 Balducci E....Rappuoli R. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 116969 HGNC: 24049 AceView: ART5 Ensembl:ENSG00000167311 euGenes: HUgn116969
ECgene: ART5 H-InvDB: ART5

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for ART5 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for ART5 gene:
Search GeneIP for patents involving ART5

GeneCards and IP:
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