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ART3 Gene

protein-coding   GIFtS: 61
GCID: GC04P076932

ADP-Ribosyltransferase 3

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
ADP-Ribosyltransferase 31 2     Ecto-ADP-Ribosyltransferase 32
Mono(ADP-Ribosyl)Transferase 32 3     mono-ADP-ribosyltransferase2
ARTC32 3     EC 2.4.2.313
ADP-Ribosyltransferase C2 And C3 Toxin-Like 32 3     TMART3
NAD(P)(+)--Arginine ADP-Ribosyltransferase 32 3     

External Ids:    HGNC: 7251   Entrez Gene: 4192   Ensembl: ENSG000001562197   OMIM: 6030865   UniProtKB: Q135083   

Export aliases for ART3 gene to outside databases

Previous GC identifers: GC04P076891 GC04P077186 GC04P077325 GC04P077454 GC04P077353 GC04P072684


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ART3 Gene:
This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction
which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function
of the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript
variants encoding different isoforms have been found for this gene. (provided by RefSeq, Dec 2011)

GeneCards Summary for ART3 Gene:
ART3 (ADP-ribosyltransferase 3) is a protein-coding gene. GO annotations related to this gene include NAD(P)+-protein-arginine ADP-ribosyltransferase activity and NAD+ ADP-ribosyltransferase activity. An important paralog of this gene is ART4.

Gene Wiki entry for ART3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000004.11  NT_016354.20  NC_018915.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ART3 gene promoter:
         AhR   IRF-2   p53   AML1a   FOXO3   IRF-1   Cdc5   FOXO3b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidART3 promoter sequence
   Search Chromatin IP Primers for ART3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ART3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1|4p15.1-p14   Ensembl cytogenetic band:  4q21.1   HGNC cytogenetic band: 4q21.1

ART3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ART3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P076932:  view genomic region     (about GC identifiers)

Start:
76,932,337 bp from pter      End:
77,033,955 bp from pter
Size:
101,619 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: NAR3_HUMAN, Q13508 (See protein sequence)
Recommended Name: Ecto-ADP-ribosyltransferase 3 precursor  
Size: 389 amino acids; 43923 Da
Secondary accessions: Q53XW3 Q6FHT7 Q8WVJ7 Q93069 Q96HL1
Alternative splicing: 3 isoforms:  Q13508-1   Q13508-2   Q13508-3   

Explore the universe of human proteins at neXtProt for ART3: NX_Q13508

Explore proteomics data for ART3 at MOPED

Post-translational modifications: 

  • O-glycosylated with core 1 or possibly core 8 glycans1
  • Glycosylation2 at Asn248, Thr346

  • See ART3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001123488.1  NP_001123489.1  NP_001170.2  

    ENSEMBL proteins: 
     ENSP00000421345   ENSP00000343843   ENSP00000422287   ENSP00000421431   ENSP00000348064  
     ENSP00000304313   ENSP00000425327   ENSP00000422249  

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    Cloud-Clone Corp. Proteins for ART3

     
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    antibodies-online proteins for ART3 (5 products) 

     
    antibodies-online peptides for ART3

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    antibodies-online antibodies for ART3 (57 products) 

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    antibodies-online kits for ART3 (4 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR000768 ART

    Graphical View of Domain Structure for InterPro Entry Q13508

    ProtoNet protein and cluster: Q13508

    1 Blocks protein domain: IPB000768 NAD:arginine ADP-ribosyltransferase

    UniProtKB/Swiss-Prot: NAR3_HUMAN, Q13508
    Similarity: Belongs to the Arg-specific ADP-ribosyltransferase family


    Find genes that share domains with ART3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: NAR3_HUMAN, Q13508
    Catalytic activity: NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine

         Genatlas biochemistry entry for ART3:
    ADP-ribosyltransferase 3,expressed in testis

         Enzyme Number (IUBMB): EC 2.4.2.311

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003950NAD+ ADP-ribosyltransferase activity TAS9119374
    GO:0003956NAD(P)+-protein-arginine ADP-ribosyltransferase activity IEA--
         
    Find genes that share ontologies with ART3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ART3:
     Increased S DNA content 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Art3):
     no phenotypic analysis 

    Find genes that share phenotypes with ART3           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ART3

    miRNA
    Products:
        
    miRTarBase miRNAs that target ART3:
    hsa-mir-122-5p (MIRT023366), hsa-mir-335-5p (MIRT018426)

    Block miRNA regulation of human, mouse, rat ART3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate ART3:
    hsa-miR-7-1* hsa-miR-7-2* hsa-miR-548s
    SwitchGear 3'UTR luciferase reporter plasmidART3 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat ART3

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    GenScript: all cDNA clones in your preferred vector (see all 3): ART3 (NM_001179)
    Sino Biological Human cDNA Clone for ART3
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ART3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART3

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    NAR3_HUMAN, Q13508: Cell membrane; Lipid-anchor, GPI-anchor
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    endoplasmic reticulum2
    extracellular1
    golgi apparatus1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral component of plasma membrane TAS9119374
    GO:0031225anchored component of membrane IEA--

    Find genes that share ontologies with ART3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ART3 About    
    See pathways by source

    SuperPathContained pathways About
    1Nicotinate and nicotinamide metabolism
    NAD metabolism0.43

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 GeneGo (Thomson Reuters) Pathway for ART3
        NAD metabolism



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ART3
    Interactions:

        Search GeneGlobe Interaction Network for ART3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ART3 (ENSP000003480644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALCAMENSP000003059884STRING: ENSP00000305988
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006471protein ADP-ribosylation IEA--

    Find genes that share ontologies with ART3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ART3 (NAR3)

    5 HMDB Compounds for ART3    About this table
    CompoundSynonyms CAS #PubMed Ids
    L-Arginine(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoate (see all 14)74-79-3--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--
    Niacinamide3-Carbamoylpyridine (see all 77)98-92-0--

    4 Novoseek inferred chemical compound relationships for ART3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adpribose 83.6 3 16140404 (1), 8871630 (1), 16278211 (1)
    nad+ 76.4 3 10068454 (1), 16140404 (1), 18165311 (1)
    arginine 35.9 2 9173879 (1)
    adp 30.3 1 11368185 (1)



    Find genes that share compounds with ART3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ART3 gene (3 alternative transcripts): 
    NM_001130016.2  NM_001130017.2  NM_001179.5  

    Unigene Cluster for ART3:

    ADP-ribosyltransferase 3
    Hs.24976  [show with all ESTs]
    Unigene Representative Sequence: BF575780
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000513353 ENST00000510669 ENST00000341029(uc003hji.3 uc003hjj.3 uc003hjk.3 uc003hjp.3 uc010ijb.3 uc003hjq.3)
    ENST00000513122 ENST00000504914 ENST00000355810(uc003hjo.3 uc003hjr.3 uc010ijc.3 uc010ijd.3)
    ENST00000349321(uc003hjn.3) ENST00000513494(uc010ija.2) ENST00000510423
    ENST00000395688 ENST00000506667 ENST00000504112 ENST00000506313 ENST00000511188
    ENST00000510863
    miRNA
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    3 qRT-PCR Assays for microRNAs that regulate ART3:
    hsa-miR-7-1* hsa-miR-7-2* hsa-miR-548s
    SwitchGear 3'UTR luciferase reporter plasmidART3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ART3
    Predesigned siRNA for gene silencing in human, mouse, rat ART3
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    Primer
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    OriGene qPCR primer pairs and template standards for ART3
    OriGene qSTAR qPCR primer pairs in human, mouse for ART3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ART3
      QuantiTect SYBR Green Assays in human, mouse, rat ART3
      QuantiFast Probe-based Assays in human, mouse, rat ART3

    Additional mRNA sequence: 

    AY543657.1 AY543658.1 AY543659.1 AY543660.1 

    4 DOTS entries:

    DT.86853054  DT.444071  DT.100778378  DT.91761603 

    Selected AceView cDNA sequences (see all 39):

    AW963604 CR541664 AA460123 BT007249 BM712556 AI138801 BI464338 BX096471 
    BI831757 U47054 BV202849 AA428241 AI201027 AI341237 AK129914 AA461477 
    BI460171 BX500857 BF575132 BC008397 BF574649 BX499574 AI366816 AA884935 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ART3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5
    SP1:                                    
    SP2:                    -     -         


    ECgene alternative splicing isoforms for ART3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ART3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTGAGAAAAA
    ART3 Expression
    About this image


    ART3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Adipose (Muscoskeletal System)    fully expand to see all 3 entries
             Body Subcutaneous White Adipose
             HyStem+BMP4-induced 7SMOO32 cells
     
     Bone (Muscoskeletal System)    fully expand to see all 3 entries
             Zeugopod Growth Plate
             TGFbeta3+BMP7-induced chondrocytes
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             TGFbeta3+BMP7-induced chondrocytes
     
     Peripheral Nervous System (Nervous System)
             Immature Schwann Cells Peripheral Nerve Domain
     
     Testis (Reproductive System)
    ART3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ART3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.24976

    UniProtKB/Swiss-Prot: NAR3_HUMAN, Q13508
    Tissue specificity: Testis specific

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ART3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Art31 , 5 ADP-ribosyltransferase 31, 5 72.39(n)1
    64.79(a)1
      5 (46.54 cM)5
    1099791  NM_181728.21  NP_859417.21 
     923318275 
    chicken
    (Gallus gallus)
    Aves --
    --
    Uncharacterized protein
    36(a)
    29(a)
    many → 1
    many → 1
    1(193914302-193915666)
    1(193927816-193928555)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    31(a)
    many ↔ many
    GL343834.1(15323-17196)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia art51 ADP-ribosyltransferase 5 51(n)
    39.76(a)
      496773  NM_001039735.1  NP_001034824.1 
    zebrafish
    (Danio rerio)
    Actinopterygii CABZ01019905.16
    CR846080.36
    (see all 13)
    Uncharacterized protein
    (see all 13)
    30(a)
    30(a)
    (see all 13)
    many ↔ many
    many ↔ many
    (see all 13)
    3(7938826-7939488) ENSDARG00000040229
    3(10211463-10212240) ENSDARG00000076211


    ENSEMBL Gene Tree for ART3 (if available)
    TreeFam Gene Tree for ART3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ART3 gene
    ART42  ART52  ART12  
    1 SIMAP similar gene for ART3 using alignment to 8 protein entries:     NAR3_HUMAN (see all proteins):
    ART5

    Find genes that share paralogs with ART3           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ART3
    PGOHUM00000242792


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ART3 (see all 2362)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1823370491,2
    --76930737(+) GCATGC/TGTGTG 1 -- us2k10--------
    rs2002347891,2
    C--76930745(+) GTGTGC/TGCGCA 1 -- us2k10--------
    rs125002001,2
    C,F,A,H--76930746(+) TGTGCG/ACGCAT 1 -- us2k113Minor allele frequency- A:0.11NS EA NA WA CSA 789
    rs1424753911,2
    --76930747(+) GTGCGC/TGCATG 1 -- us2k10--------
    rs42415771,2
    C,F,A--76930776(+) CACACC/ACCCCC 1 -- us2k15Minor allele frequency- A:0.20NA WA EA 362
    rs1459278651,2
    --76930779(+) ACCCCC/TCCACA 1 -- us2k10--------
    rs2019360891,2
    C--76930782(+) CCCCCA/CCATTT 1 -- us2k10--------
    rs1866226201,2
    --76930795(+) CCTTGC/TTCTGA 1 -- us2k10--------
    rs126512761,2
    C,F,H--76930869(+) AGAAAT/GAAGAT 1 -- us2k1 tfbs316Minor allele frequency- G:0.23NS EA NA WA 2338
    rs1911238161,2
    --76930903(+) GGTAGG/TCCACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ART3 (76932337 - 77033955 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ART3 (see all 18):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662680CNV Deletion23128226
    esv2727841CNV Deletion23290073
    esv2676154CNV Deletion23128226
    esv2660008CNV Deletion23128226
    nsv821336CNV Deletion20802225
    esv2427313CNV Deletion19546169
    esv2225549CNV Deletion18987734
    esv2727842CNV Deletion23290073
    nsv293489CNV Insertion16902084
    esv272627CNV Insertion20981092

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 603086    OMIM disorders: --


    Find genes that share disorders with ART3           About GenesLikeMe

    Genetic Association Database (GAD): ART3
    Human Genome Epidemiology (HuGE) Navigator: ART3 (6 documents)

    Export disorders for ART3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ART3 gene, integrated from 10 sources (see all 43):
    (articles sorted by number of sources associating them with ART3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins. (PubMed id 9119374)1, 2, 3 Koch-Nolte F.... Thiele H.-G. (Genomics 1997)
    2. Genome-wide expression of azoospermia testes demonstrates a specific profile and implicates ART3 in genetic susceptibility. (PubMed id 18266473)1, 4, 9 Okada H....Inoue I. (PLoS Genet. 2008)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Human testis specifically expresses a homologue of the rodent T lymphocytes RT6 mRNA. (PubMed id 8605984)1, 2 Levy I.... Guellaen G. (FEBS Lett. 1996)
    7. Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes. (PubMed id 16625277)1, 9 Friedrich M....Hauschildt S. (Asian J. Androl. 2006)
    8. Genomic organization and expression of the human mono-ADP- ribosyltransferase ART3 gene. (PubMed id 16934346)1, 9 Friedrich M....Hauschildt S. (Biochim. Biophys. Acta 2006)
    9. Analysis of the 3' UTR of the ART3 and ART4 gene by 3' inverse RACE- PCR. (PubMed id 16040347)1, 9 Friedrich M.... Hauschildt S. (DNA Seq. 2005)
    10. Mono-ADP-ribosyltransferases in human monocytes: regulation by lipopolysaccharide. (PubMed id 11879200)1, 9 Grahnert A....Hauschildt S. (Biochem. J. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 419 HGNC: 725 AceView: ART3 Ensembl:ENSG00000156219 euGenes: HUgn419
    ECgene: ART3 H-InvDB: ART3

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ART3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ART3 gene:
    Search GeneIP for patents involving ART3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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