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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ART3 Gene

protein-coding   GIFtS: 60
GCID: GC04P076932

ADP-ribosyltransferase 3
 Explore 9 diseases affiliated with
ART3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ART3    

Aliases
for ART3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
ADP-Ribosyltransferase 31 2     Ecto-ADP-Ribosyltransferase 32
Mono(ADP-Ribosyl)Transferase 32 3     Mono-ADP-Ribosyltransferase1
ARTC32 3     EC 2.4.2.313
ADP-Ribosyltransferase C2 And C3 Toxin-Like 32 3     TMART3
NAD(P)(+)--Arginine ADP-Ribosyltransferase 32 3     

External Ids:    HGNC: 7251   Entrez Gene: 4192   Ensembl: ENSG000001562197   OMIM: 6030865   UniProtKB: Q135083   

Export aliases for ART3 gene to outside databases

Previous GC identifers: GC04P076891 GC04P077186 GC04P077325 GC04P077454 GC04P077353 GC04P072684


Summaries
for ART3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for ART3:
This gene encodes an arginine-specific ADP-ribosyltransferase. The encoded protein catalyzes a reversible reaction
which modifies proteins by the addition or removal of ADP-ribose to an arginine residue to regulate the function of
the modified protein. An ADP-ribosyltransferase pseudogene is located on chromosome 11. Multiple transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, Dec 2011)

Gene Wiki entry for ART3


Genomic Views
for ART3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NC_018915.1  NT_016354.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ART3 gene promoter:
         AhR   IRF-2   p53   AML1a   FOXO3   IRF-1   Cdc5   FOXO3b   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ART3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ART3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ART3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q21.1|4p15.1-p14   Ensembl cytogenetic band:  4q21.1   HGNC cytogenetic band: 4q21.1

ART3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ART3 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04P076932:  view genomic region     (about GC identifiers)

Start:
 76,932,337 bp from pter      End:
 77,033,955 bp from pter
Size:
 101,619 bases      Orientation:
 plus strand

Proteins
for ART3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: NAR3_HUMAN, Q13508 (See protein sequence)
Recommended Name: Ecto-ADP-ribosyltransferase 3 precursor  
Size: 389 amino acids; 43923 Da
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor
Secondary accessions: Q53XW3 Q6FHT7 Q8WVJ7 Q93069 Q96HL1
Alternative splicing: 3 isoforms:  Q13508-1   Q13508-2   Q13508-3   

Explore the universe of human proteins at neXtProt for ART3: NX_Q13508

Post-translational modifications:

  • O-glycosylated with core 1 or possibly core 8 glycans1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q13508

    • ART3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001123488.1  NP_001123489.1  NP_001170.2  

    ENSEMBL proteins: 
     ENSP00000421345   ENSP00000343843   ENSP00000422287   ENSP00000421431   ENSP00000348064  
     ENSP00000304313   ENSP00000425327   ENSP00000422249  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: ART3
    OriGene Custom Protein Services for ART3 
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    Novus Biologicals ART3 Proteins
    Novus Biologicals ART3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ART3

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005887integral to plasma membrane TAS9119374
    GO:0031225anchored to membrane IEA--


    ART3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for ART3

    Protein Domains /
    Families
    for ART3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ART3 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR000768 ART

    Graphical View of Domain Structure for InterPro Entry Q13508

    ProtoNet protein and cluster: Q13508

    1 Blocks protein family: IPB000768 NAD:arginine ADP-ribosyltransferase

    UniProtKB/Swiss-Prot: NAR3_HUMAN, Q13508
    Similarity: Belongs to the Arg-specific ADP-ribosyltransferase family


    Function
    for ART3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: NAR3_HUMAN, Q13508
    Catalytic activity: NAD(+) + protein-L-arginine = nicotinamide + N(omega)-(ADP-D-ribosyl)-protein-L-arginine
    Catalytic activity: NADP(+) + protein-L-arginine = nicotinamide +
    N(omega)-((2'-phospho-ADP)-D-ribosyl)-protein-L-arginine

         Genatlas biochemistry entry for ART3:
    ADP-ribosyltransferase 3,expressed in testis

    Enzyme Number (IUBMB): EC 2.4.2.311

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ART3
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate ART3:
    hsa-miR-7-1* hsa-miR-7-2* hsa-miR-548s
    SwitchGear 3'UTR luciferase reporter plasmid: ART3 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ART3 (see all 7)
    OriGene shRNA RFP: ART3
    OriGene siRNA: ART3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ART3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for ART3

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ART3 (see all 5)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): ART3 (NM_001179)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ART3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART3 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for ART3
    Search LifeMap BioReagents cell lines for ART3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART3

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003950NAD+ ADP-ribosyltransferase activity TAS9119374
    GO:0003956NAD(P)+-protein-arginine ADP-ribosyltransferase activity IEA--


    ART3 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for ART3:
     Increased S DNA content 

    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Art3):
     no phenotypic analysis 

    ART3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ART3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1NAD metabolism
    		NAD metabolism1.00
    		NAD metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for ART3
        NAD metabolism


    1 GeneGo (Thomson Reuters) Pathway for ART3
        NAD metabolism



    ART3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ART3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for ART3 (ENSP000003480644) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ALCAMENSP000003059884STRING: ENSP00000305988
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006471protein ADP-ribosylation IEA--


    ART3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ART3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ART3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ART3

    5 HMDB Compounds for ART3    About this table
    CompoundSynonyms CAS #PubMed Ids
    L-Arginine(S)-2-Amino-5-[(aminoiminomethyl)amino]pentanoate (see all 14)74-79-3--
    NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--
    NADH1,4-Dihydronicotinamide adenine dinucleotide (see all 17)58-68-4--
    NADPAdenine-nicotinamide dinucleotide phosphate (see all 18)53-59-8--
    Niacinamide3-Carbamoylpyridine (see all 77)98-92-0--
    4 Novoseek chemical compound relationships for ART3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adpribose 83.6 3 16140404 (1), 8871630 (1), 16278211 (1)
    nad+ 76.4 3 10068454 (1), 16140404 (1), 18165311 (1)
    arginine 35.9 2 9173879 (1)
    adp 30.3 1 11368185 (1)

    Search CenterWatch for drugs/clinical trials and news about ART3 / NAR3 

    Transcripts
    for ART3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ART3 gene (3 alternative transcripts): 
    NM_001130016.2  NM_001130017.2  NM_001179.5  

    Unigene Clusters for ART3:

    ADP-ribosyltransferase 3
    Hs.24976  [show with all ESTs], Hs.731997  [show with all ESTs]
    Unigene Representative Sequences: BF575780, NM_001130016
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000513353 ENST00000510669 ENST00000341029(uc003hji.3 uc003hjj.3 uc003hjk.3 uc003hjp.3 uc010ijb.3 uc003hjq.3)
    ENST00000513122 ENST00000504914 ENST00000355810(uc003hjo.3 uc003hjr.3 uc010ijc.3 uc010ijd.3)
    ENST00000349321(uc003hjn.3) ENST00000513494(uc010ija.2) ENST00000510423
    ENST00000395688 ENST00000506667 ENST00000504112 ENST00000506313 ENST00000511188
    ENST00000510863

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ART3
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate ART3:
    hsa-miR-7-1* hsa-miR-7-2* hsa-miR-548s
    SwitchGear 3'UTR luciferase reporter plasmid: ART3 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ART3 (see all 7)
    OriGene shRNA RFP: ART3
    OriGene siRNA: ART3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ART3
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ART3 (see all 5)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 3): ART3 (NM_001179)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ART3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ART3 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ART3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ART3

    Additional cDNA sequence: 

    AK225860.1 AK295305.1 AK308810.1 AY543655.1 AY543656.1 AY550337.1 AY550338.1 AY550339.1 
    AY550340.1 AY550341.1 AY550342.1 AY550343.1 AY550344.1 AY550345.1 AY550346.1 BC008397.1 
    BC017913.1 BT007249.1 CR541664.1 U47054.1 

    9 DOTS entries:

    DT.444071  DT.86853054  DT.95372967  DT.100778378  DT.95153626  DT.91761603  DT.100778376  DT.101959652 
    DT.40110198 

    24/39 AceView cDNA sequences (see all 39):

    AI138801 AW963604 CR541664 BM712556 AA460123 BT007249 BX096471 BC008397 
    BV202849 BF574649 BI460171 AA461477 U47054 AA428241 AI366816 BF575132 
    BX500857 BX499574 AI201027 AK129914 BI831757 BI464338 AI341237 AI698534 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ART3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5
    SP1:                                    
    SP2:                    -     -         


    ECgene alternative splicing isoforms for ART3

    Expression
    for ART3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ART3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GTGAGAAAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ART3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyS-shaped BodyKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 4 LifeMap Cells 
    NameCategory
    PureStem™ progenitor SK17 (Embryonic Progenitor Cell)
    HyStem+BMP4-induced SK11 cells (HyStem+BMP4 inductio...)Bone, Cartilage
    HyStem+BMP4-induced 7SMOO32 cells (HyStem+BMP4 inductio...)Adipose
    TGF?3+BMP7-induced chondrocytes (Chondrogenic HyStem+...)Bone, Cartilage

    See ART3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ART3

    SOURCE GeneReport for Unigene clusters: Hs.24976 Hs.731997

    UniProtKB/Swiss-Prot: NAR3_HUMAN, Q13508
    Tissue specificity: Testis specific

        SABiosciences Custom PCR Arrays for ART3
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ART3
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ART3

    Orthologs
    for ART3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for ART3 gene from 3/9 species (see all 9)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Art31 , 5 ADP-ribosyltransferase 31, 5 72.98(n)1
    65.54(a)1    		   5 (46.54 cM)5
    1099791  NM_181728.21  NP_859417.21 
     923318275 
    chicken
    (Gallus gallus)    		 Aves ART56
    		 --
    		 32(a)
    		 possible ortholog
    		 Un(63088163-63089169)
    zebrafish
    (Danio rerio)    		 Actinopterygii CR846080.46
    CABZ01019905.16
    (see all 14)    		 --
    		 27(a)
    27(a)
    (see all 14)    		 many ↔ many
    many ↔ many
    (see all 14)    		 3(10211463-10212240)
    3(7938826-7939488)


    ENSEMBL Gene Tree for ART3 (if available)
    TreeFam Gene Tree for ART3 (if available) 

    Paralogs
    for ART3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ART3 gene
    ART42  ART52  ART12  
    1 SIMAP similar gene for ART3 using alignment to 8 protein entries:     NAR3_HUMAN (see all proteins):
    ART5

    ART3 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ART3
    PGOHUM00000242792


    Genomic Variants
    for ART3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for ART3
         2 CNVs: 98758 63866
         3 Indels: 12469 63865 46694
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ART3
    DNA2.0 Custom Variant and Variant Library Synthesis for ART3

    Disorders / Diseases
    for ART3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ART3 for disorders           About GeneDecksing

    OMIM gene information: 603086    OMIM disorders: --

    9 diseases for ART3:    About MalaCards
    diphtheria    azoospermia    gastric adenocarcinoma    hepatitis b
    cholera    hepatocellular carcinoma    adenocarcinoma    hepatitis
    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: ART3 (6 documents)

    Export disorders for ART3 gene to outside databases

    Publications
    for ART3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ART3 gene, integrated from 9 sources (see all 42):
    (articles sorted by number of sources associating them with ART3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Two novel human members of an emerging mammalian gene family related to mono-ADP-ribosylating bacterial toxins. (PubMed id 9119374)1, 2, 3 Koch-Nolte F.... Thiele H.-G. (1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Human testis specifically expresses a homologue of the rodent T lymphocytes RT6 mRNA. (PubMed id 8605984)1, 2 Levy I.... Guellaen G. (1996)
    4. Expression of toxin-related human mono-ADP-ribosyltransferase 3 in human testes. (PubMed id 16625277)1, 9 Friedrich M....Hauschildt S. (2006)
    5. Genomic organization and expression of the human mono-ADP- ribosyltransferase ART3 gene. (PubMed id 16934346)1, 9 Friedrich M....Hauschildt S. (2006)
    6. Analysis of the 3' UTR of the ART3 and ART4 gene by 3' inverse RACE-PCR. (PubMed id 16040347)1, 9 Friedrich M....Hauschildt S. (2005)
    7. Genome-wide expression of azoospermia testes demonstrates a specific profile and implicates ART3 in genetic susceptibility. (PubMed id 18266473)1, 9 Okada H....Inoue I. (2008)
    8. Mono-ADP-ribosyltransferases in human monocytes: regulation by lipopolysaccharide. (PubMed id 11879200)1, 9 Grahnert A....Hauschildt S. (2002)
    9. Selective expression of RT6 superfamily in human bronchial epithelial cells. (PubMed id 10460751)1, 9 Balducci E....Moss J. (1999)
    10. Human urinary glycoproteomics; attachment site specific analysis of N-and O-linked glycosylations by CID and ECD. (PubMed id 22171320)2 Halim A.... Larson G. (2011)

    External Searches for ART3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing ART3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 419 HGNC: 725 AceView: ART3 Ensembl:ENSG00000156219 euGenes: HUgn419
    ECgene: ART3 H-InvDB: ART3

    Other Databases showing ART3 gene

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    Specialized Databases showing ART3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for ART3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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    		Patent Information for ART3 gene:
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