ARSK Gene
protein-coding GIFtS: 50
GCID: GC05P094917
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|
arylsulfatase family, member K(Previous name: arylsulfatase K )
| |
Aliases for ARSK gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Arylsulfatase Family, Member K1 2 | | ASK2 3 | | TSULF1 2 3 | | DKFZp313G17351 | | Arylsulfatase K1 2 | | EC 3.1.6.-3 | | Telethon Sulfatase2 3 | | EC 3.1.68 |
Export aliases for ARSK gene to outside databasesPrevious GC identifer: GC05P090081 |
Summaries for ARSK gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ARSK: Sulfatases (EC 3.1.5.6), such as ARSK, hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans,and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation ofmacromolecules (Sardiello et al., 2005 (PubMed 16174644)).(supplied by OMIM, Mar 2008)
|
Genomic Views for ARSK gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_034772.6
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ARSK gene promoter: E2F-4 TBP E2F-5 GATA-3 Lmo2 GATA-1 GATA-2 PPAR-alpha HFH-1 ATF6 Other transcription factors
Search SABiosciences Chromatin IP Primers for ARSK
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARSK |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q15 Ensembl cytogenetic band: 5q15 HGNC cytogenetic band: 5q15ARSK Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05P094917: view genomic region
(about GC identifiers)
Start:
|
94,890,778 bp from pter |
End:
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94,940,806 bp from pter |
Size:
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50,029 bases |
Orientation:
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plus strand |
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Proteins for ARSK gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ARSK_HUMAN, Q6UWY0 (See
protein sequence)Recommended Name: Arylsulfatase K precursor Size: 536 amino acids; 61450 Da
Cofactor: Binds 1 calcium ion per subunit (By similarity)
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=AAH36047.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A2BDE3 B4E1I4 Q3ZCW3 Q8N3Q8Explore the universe of human proteins at neXtProt for ARSK: NX_Q6UWY0
Post-translational modifications:
The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotesand of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6UWY0 4/17 DME Specific Peptides for ARSK (Q6UWY0) (see all 17)
ARSK Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_937793.1 ENSEMBL proteins: ENSP00000369346 ENSP00000422608 ENSP00000422126 ENSP00000423636 ENSP00000424018 Reactome Protein details: Q6UWY0 Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- | | GO:0005788 | endoplasmic reticulum lumen |
TAS | -- |
ARSK for ontologies About GeneDecksing
ARSK Antibody Products: Assay Products for ARSK: |
Protein
Domains / Families for ARSK gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARSK for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6UWY0ProtoNet protein and cluster: Q6UWY0 1 Blocks protein family: IPB000917 Sulfatase
UniProtKB/Swiss-Prot: ARSK_HUMAN, Q6UWY0Similarity: Belongs to the sulfatase family |
Function for ARSK gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Enzyme Numbers (IUBMB): EC 3.1.6.-1 EC 3.1.62
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARSK (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARSK OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ARSK (NM_198150) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARSK | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARSK  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARSK |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ARSK for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ARSK: Animal Models: 1 MGI phenotypic allele for Arsk (no phenotypes)
ARSK for phenotypes About GeneDecksing
|
Pathways & Interactions for ARSK gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Sphingolipid metabolism | | | 2 | PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | | | 3 | Metabolism | | | 4 | Asparagine N-linked glycosylation | |
Pathway sources See GeneCards unified pathways Show all pathways
5/8
Reactome Pathways for ARSK (see all 8)
ARSK for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARSK
STRING Interaction
Network Preview (showing 5 interactants - click image to see 11)
 5/11 Interacting proteins for ARSK (ENSP000003693464) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006644 | phospholipid metabolic process |
TAS | -- | | GO:0006665 | sphingolipid metabolic process |
TAS | -- | | GO:0006687 | glycosphingolipid metabolic process |
TAS | -- | | GO:0043687 | post-translational protein modification |
TAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- |
ARSK for ontologies About GeneDecksing
|
Drugs & Compounds for ARSK gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for ARSK
1 HMDB Compound for ARSK About this table Search CenterWatch for drugs/clinical trials and news about ARSK 
|
Transcripts for ARSK gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ARSK gene: NM_198150.2 Unigene Cluster for ARSK: Arylsulfatase family, member K Hs.585051 [show with all ESTs]Unigene Representative Sequence: NM_1981505 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000380009(uc003kld.3 uc010jbg.3 uc011cum.2) ENST00000513814 ENST00000504763(uc003klc.3) ENST00000504873 ENST00000512106
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARSK (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARSK OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ARSK (NM_198150) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARSK | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARSK  |
Additional cDNA sequence: AK303855.1 AK316253.1 AL832711.1 AY358596.1 AY875939.1 BC015723.2 BC036047.1 BC050392.1 BC080567.1 BC130329.1 BC144160.1 BC144161.1 4 DOTS entries: DT.40238437 DT.428830 DT.97832036 DT.97832037 24/57 AceView cDNA sequences (see all 57): BU630043 BX109484 NM_198150 AI243677 AA883670 AA314107 BC080567 BE295686 AI421965 BU527024 AW069167 BM923547 CA397780 CA442752 AA565548 AA548225 AY358596 BF478009 BC050392 AK126218 BF437866 AL832711 BG035392 BX107909 GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ARSK About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | |
| SP1: | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ARSK
|
Expression for ARSK gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARSK expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TTGCTTCTTT
About this image See ARSK Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ARSK
SOURCE GeneReport for Unigene cluster: Hs.585051 SABiosciences Custom PCR Arrays for ARSK
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARSK Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARSK | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARSK | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARSK | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARSK |
Orthologs for ARSK gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ARSK gene from 6/13 species (see all 13) About this table
ENSEMBL Gene Tree for ARSK (if available) TreeFam Gene Tree for ARSK (if available)  |
Paralogs for ARSK gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ARSK gene
- SULF12 GNS2 SULF22
1 SIMAP similar gene for ARSK using alignment to 6 protein entries: ARSK_HUMAN (see all proteins):SULF1
ARSK for paralogs About GeneDecksing
|
Genomic Variants for ARSK gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 5 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ARSK (94890778 - 94940806 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for ARSK 1 CNV: 4465  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARSK |
|
Disorders
/ Diseases for ARSK gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARSK for disorders About MalaCards
ARSK for disorders About GeneDecksing
OMIM gene information: 610011
OMIM disorders: --
Export disorders for ARSK gene to outside databases
|
Publications for ARSK gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARSK gene integrated from 9 sources: (articles sorted by number of sources associating them with ARSK) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship. (PubMed id 16174644)1, 2, 3 Sardiello M....Ballabio A. (2005)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
- Molecular cloning and initial characterization of three novel human sulfatases. (PubMed id 16500042)1, 2 Obaya A.J. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for ARSK gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ARSK gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARSK gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ARSK gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for ARSK | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ARSK gene: Search GeneIP for patents involving ARSK
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for ARSK gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for ARSK | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARSK | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARSK | | OriGene Protein Over-expression Lysate for ARSK | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ARSK | | OriGene 3'-UTR Clone for ARSK | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARSK | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARSK | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ARSK | | OriGene Custom Protein Services for ARSK | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARSK | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARSK | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARSK | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARSK | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARSK | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARSK |
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 |  |  |  | |
| | | Search Tocris compounds for ARSK |
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 | | ARSK Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARSK |
|  |  |  | | | Search ThermoFisher Antibodies for ARSK |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARSK |
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