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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARSJ Gene

protein-coding   GIFtS: 55
GCID: GC04M114821

Arylsulfatase Family, Member J

(Previous name: arylsulfatase J)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Arylsulfatase Family, Member J1 2
Arylsulfatase J1 2
ASJ2 3
EC 3.1.6.-3
EC 3.1.68
EC 3.1.6.128

External Ids:    HGNC: 262861   Entrez Gene: 796422   Ensembl: ENSG000001808017   OMIM: 6100105   UniProtKB: Q5FYB03   

Export aliases for ARSJ gene to outside databases

Previous GC identifers: GC04M115180 GC04M115040 GC04M110549


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARSJ Gene:
Sulfatases (EC 3.1.5.6), such as ARSJ, hydrolyze sulfate esters from sulfated steroids, carbohydrates,
proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and
degradation of macromolecules (Sardiello et al., 2005 (PubMed 16174644)).(supplied by OMIM, Mar 2008)

GeneCards Summary for ARSJ Gene: 
ARSJ (arylsulfatase family, member J) is a protein-coding gene. Diseases associated with ARSJ include mucopolysaccharidosis, and alcohol dependence, and among its related super-pathways are Sphingolipid metabolism and The activation of arylsulfatases. GO annotations related to this gene include arylsulfatase activity and metal ion binding. An important paralog of this gene is ARSF.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_016354.19  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARSJ gene promoter:
         TBP   LHX3b/Lhx3b   HOXA3   Tal-1   FOXL1   C/EBPalpha   E47   IRF-2   LHX3a/Lhx3a   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARSJ promoter sequence
   Search SABiosciences Chromatin IP Primers for ARSJ

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARSJ


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4q26   Ensembl cytogenetic band:  4q26   HGNC cytogenetic band: 4q26

ARSJ Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARSJ gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M114821:  view genomic region     (about GC identifiers)

Start:
114,821,440 bp from pter      End:
114,900,883 bp from pter
Size:
79,444 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARSJ_HUMAN, Q5FYB0 (See protein sequence)
Recommended Name: Arylsulfatase J precursor  
Size: 599 amino acids; 67235 Da
Cofactor: Binds 1 calcium ion per subunit (By similarity)
Subcellular location: Secreted (Potential)
Sequence caution: Sequence=AAQ89010.1; Type=Frameshift; Positions=425;
Secondary accessions: A2RUG0 B7ZM45 Q1HA39 Q5FWE4 Q6UWT9

Explore the universe of human proteins at neXtProt for ARSJ: NX_Q5FYB0

Explore proteomics data for ARSJ at MOPED 

Post-translational modifications:

  • UniProtKB: The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in
    prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5FYB0

  • 4/8 DME Specific Peptides for ARSJ (Q5FYB0) (see all 8)
     DVGYHGS  QPNCLPLD  KGTYWEGG  PTRRGFDT 

    ARSJ Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARSJ Protein Expression
    REFSEQ proteins: NP_078866.3  
    ENSEMBL proteins: 
     ENSP00000320219   ENSP00000421327   ENSP00000438836  
    Reactome Protein details: Q5FYB0
    Human Recombinant Protein Products for ARSJ: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for ARSJ
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    Novus Biologicals ARSJ Protein
    Novus Biologicals ARSJ Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ARSJ 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--
    GO:0005788endoplasmic reticulum lumen TAS--

    ARSJ for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for ARSJ 
    Cloud-Clone Corp. CLIAs for ARSJ


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARS: Arylsulfatase family

    4 InterPro protein domains:
     IPR000917 Sulfatase
     IPR017849 Alkaline_Pase-like_a/b/a
     IPR024607 Sulfatase_CS
     IPR017850 Alkaline_phosphatase_core

    Graphical View of Domain Structure for InterPro Entry Q5FYB0

    ProtoNet protein and cluster: Q5FYB0

    1 Blocks protein domain: IPB000917 Sulfatase

    UniProtKB/Swiss-Prot: ARSJ_HUMAN, Q5FYB0
    Similarity: Belongs to the sulfatase family


    ARSJ for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Enzyme Numbers (IUBMB): EC 3.1.6.-1 EC 3.1.6.122 EC 3.1.62

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004065arylsulfatase activity TAS16174644
    GO:0008484sulfuric ester hydrolase activity ----
    GO:0046872metal ion binding IEA--
         
    ARSJ for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARSJ 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ARSJ

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARSJ 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARSJ 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARSJ
    8/35 QIAGEN miScript miRNA Assays for microRNAs that regulate ARSJ (see all 35):
    hsa-miR-142-5p hsa-miR-520f hsa-miR-3607-3p hsa-miR-330-5p hsa-miR-106a hsa-miR-513a-5p hsa-miR-570 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidARSJ 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Clone
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    OriGene ORF clones in mouse, rat for ARSJ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARSJ


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ARSJ About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Sphingolipid metabolism
    Sphingolipid metabolism0.63
    Glycosphingolipid metabolism0.55
    2PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
    PTM: gamma carboxylation, hypusine formation and arylsulfatase activation0.46
    The activation of arylsulfatases0.46
    3Metabolism
    Metabolism0.40
    Metabolism of lipids and lipoproteins0.34
    4Asparagine N-linked glycosylation
    Post-translational protein modification0.44
    Metabolism of proteins0.35

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    5/8        Reactome Pathways for ARSJ (see all 8)
        Sphingolipid metabolism
    Glycosphingolipid metabolism
    Metabolism
    PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
    Metabolism of proteins



    ARSJ for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARSJ

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/11 Interacting proteins for ARSJ (ENSP000003202194) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARSAENSP000002161244STRING: ENSP00000216124
    ARSBENSP000002649144STRING: ENSP00000264914
    ARSDENSP000003705464STRING: ENSP00000370546
    ARSEENSP000003705264STRING: ENSP00000370526
    ARSFENSP000003523194STRING: ENSP00000352319
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006665sphingolipid metabolic process TAS--
    GO:0006687glycosphingolipid metabolic process TAS--
    GO:0008152metabolic process ----
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    ARSJ for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARSJ

    1 HMDB Compound for ARSJ    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about ARSJ

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARSJ gene: 
    NM_024590.3  

    Unigene Cluster for ARSJ:

    Arylsulfatase family, member J
    Hs.22895  [show with all ESTs]
    Unigene Representative Sequence: NM_024590
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000315366(uc003ibq.1 uc010imu.1) ENST00000509829(uc010imv.1)
    ENST00000503013 ENST00000541197
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARSJ
    8/35 QIAGEN miScript miRNA Assays for microRNAs that regulate ARSJ (see all 35):
    hsa-miR-142-5p hsa-miR-520f hsa-miR-3607-3p hsa-miR-330-5p hsa-miR-106a hsa-miR-513a-5p hsa-miR-570 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidARSJ 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARSJ
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    GenScript: all cDNA clones in your preferred vector: ARSJ (NM_024590)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARSJ
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARSJ
    Sirion Biotech Customized lentivirus for stable overexpression of ARSJ 
                         Customized lentivirus expression plasmids for stable overexpression of ARSJ 
    Primer
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    OriGene qPCR primer pairs and template standards for ARSJ
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARSJ
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARSJ
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARSJ

    Additional mRNA sequence: 

    AK027201.1 AM049401.1 AY358647.1 AY875938.1 BC032010.1 BC033156.1 BC089445.1 BC132879.1 
    BC132881.1 BC142701.1 BC144265.1 BC151213.1 

    4 DOTS entries:

    DT.102829975  DT.40208583  DT.404969  DT.91651535 

    24/26 AceView cDNA sequences (see all 26):

    AI087279 BC033156 CA489050 AI867679 AW470213 BF307503 BX475192 BG680752 
    BC032010 AY358647 BQ922785 CF995649 NM_024590 CB160803 BG772761 BQ957093 
    BF939415 AA642619 BX475395 BX486174 BX952792 BX486046 BX952793 BE544501 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ARSJ    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6
    SP1:        -                           
    SP2:              -     -     -         


    ECgene alternative splicing isoforms for ARSJ

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARSJ expression in normal human tissues (normalized intensities)      ARSJ embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CGTGAGGGAA
    ARSJ Expression
    About this image


    ARSJ expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Endothelium (Cardiovascular System)    fully expand to see all 2 entries
             CD31, CD144 positive cells ( Two-step protocol for endothelial differentiation by...
             huvec   
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             Zeugopod Growth Plate
     
     Heart (Cardiovascular System)
             Atrioventricular Node Cells Atrioventricular Node
     
     Umbilical Cord (Extraembryonic Tissues)
             huvec   
     
     Kidney (Urinary System)
             Metanephric Mesenchyme Cells Metanephric Mesenchyme

    See ARSJ Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARSJ

    SOURCE GeneReport for Unigene cluster: Hs.22895
        SABiosciences Custom PCR Arrays for ARSJ
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARSJ

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARSJ gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arsj1 , 5 arylsulfatase J1, 5 86.99(n)1
    90.12(a)1
      3 (55.97 cM)5
    2719701  NM_173451.31  NP_775627.11 
     1263638275 
    chicken
    (Gallus gallus)
    Aves ARSJ1 arylsulfatase family, member J 77.97(n)
    84.97(a)
      422687  XM_420639.3  XP_420639.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    ARSJ6
    Uncharacterized protein
    84(a)
    83(a)
    1 ↔ many
    1 ↔ many
    AAWZ02036864(19760-21377)
    5(142267221-142309635)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5598001 uncharacterized LOC559800 67.84(n)
    73.83(a)
      559800  XM_683173.2  XP_688265.2 
    worm
    (Caenorhabditis elegans)
    Secernentea sul-31 Protein SUL-3 47.78(n)
    38.6(a)
      183778  NM_001047766.2  NP_001041231.1 


    ENSEMBL Gene Tree for ARSJ (if available)
    TreeFam Gene Tree for ARSJ (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARSJ gene
    ARSF2  ARSI2  ARSG2  ARSA2  STS2  ARSH2  ARSB2  GALNS2  
    ARSE2  ARSD2  
    4 SIMAP similar genes for ARSJ using alignment to 3 protein entries:     ARSJ_HUMAN (see all proteins):
    ARSI    ARSB    ARSE    IDS

    ARSJ for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1718 SNPs in ARSJ are shown (see all 1718)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs359865251,2
    C--114623999(+) GAGGG-/TGATGGG 1 -- int12Minor allele frequency- TG:0.25NA 4
    rs1485943491,2
    --114820950(+) CATTTC/TCAGTA 1 -- int10--------
    rs1429627891,2
    C--114821065(+) AATTTA/GCCTCT 1 -- int10--------
    rs1825534681,2
    --114821162(+) CTAGTC/GCTGTG 1 -- int10--------
    rs68166111,2
    C,F,H--114821256(+) TAAGAT/CTTTAA 1 -- int115Minor allele frequency- C:0.09NS EA CSA WA 2216
    rs1511017661,2
    C--114821524(+) TTTACA/GCTATA 1 -- ut310--------
    rs1876856471,2
    --114821786(+) CAGATC/TACAGT 1 -- ut310--------
    rs68456641,2
    C,F,H--114821980(+) TCCTCA/GTGACG 1 -- ut3110Minor allele frequency- G:0.07NS EA NA WA 1212
    rs1398699881,2
    --114822011(+) GCAAGA/GTTACC 1 -- ut310--------
    rs795169491,2
    C,F--114822073(+) CCACTT/GTGTAT 1 -- ut311Minor allele frequency- G:0.03EA 120

    HapMap Linkage Disequilibrium report for ARSJ (114821440 - 114900883 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for ARSJ:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2320119CNV Deletion18987734
    esv2728165CNV Deletion23290073
    esv2728164CNV Deletion23290073
    esv2728163CNV Deletion23290073
    nsv524515CNV Gain19592680
    nsv525087CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610010    OMIM disorders: --

    4 diseases for ARSJ:    About MalaCards
    mucopolysaccharidosis    alcohol dependence    alcoholism    tuberculosis


    ARSJ for disorders           About GeneDecksing

    Genetic Association Database (GAD): ARSJ
    Human Genome Epidemiology (HuGE) Navigator: ARSJ (1 document)

    Export disorders for ARSJ gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARSJ gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with ARSJ)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sulfatases and sulfatase modifying factors: an exclusive and promiscuous relationship. (PubMed id 16174644)1, 2, 3 Sardiello M....Ballabio A. (2005)
    2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2, 3 Clark H.F.... Gray A.M. (2003)
    3. A systematic gene-based screen of chr4q22-q32 identif ies association of a novel susceptibility gene, DKK2, with the quantitative tra it of alcohol dependence symptom counts. (PubMed id 20332099)1, 4 Kalsi G....Riley B.P. (2010)
    4. Molecular cloning and initial characterization of three novel human sulfatases. (PubMed id 16500042)1, 2 Obaya A.J. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (2007)
    7. Genome-wide association with select biomarker traits in the Framingham Heart Study. (PubMed id 17903293)4 Benjamin E.J....Vasan R.S. (2007)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    9. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W....Wilson R.K. (2005)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79642 HGNC: 26286 AceView: FLJ23548 Ensembl:ENSG00000180801 euGenes: HUgn79642
    ECgene: ARSJ H-InvDB: ARSJ

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARSJ Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARSJ gene:
    Search GeneIP for patents involving ARSJ

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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