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ARSF Gene

protein-coding   GIFtS: 59
GCID: GC0XP002978

Arylsulfatase F

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Arylsulfatase F1 2
ASF2 3
EC 3.1.6.-3
EC 3.1.68
EC 3.1.6.28

External Ids:    HGNC: 7211   Entrez Gene: 4162   Ensembl: ENSG000000620967   OMIM: 3000035   UniProtKB: P547933   

Export aliases for ARSF gene to outside databases

Previous GC identifers: GC0XP002264 GC0XP002158 GC0XP002514 GC0XP002579 GC0XP000927


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ARSF Gene:
This gene is a member of the sulfatase family, and more specifically, the arylsulfatase subfamily. Members of the
subfamily share similarity in sequence and splice sites, and are clustered together on chromosome X, suggesting
that they are derived from recent gene duplication events. Sulfatases are essential for the correct composition
of bone and cartilage matrix. The activity of this protein, unlike that of arylsulfatase E, is not inhibited by
warfarin. Multiple alternatively spliced variants, encoding the same protein, have been identified.(provided by
RefSeq, Jan 2011)

GeneCards Summary for ARSF Gene:
ARSF (arylsulfatase F) is a protein-coding gene. Diseases associated with ARSF include chondrodysplasia, and tuberculosis. GO annotations related to this gene include arylsulfatase activity. An important paralog of this gene is ARSI.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_167197.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for ARSF
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARSF promoter sequence
   Search Chromatin IP Primers for ARSF

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARSF


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.3   Ensembl cytogenetic band:  Xp22.33   HGNC cytogenetic band: Xp22.3

ARSF Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARSF gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP002978:  view genomic region     (about GC identifiers)

Start:
2,958,275 bp from pter      End:
3,030,770 bp from pter
Size:
72,496 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ARSF_HUMAN, P54793 (See protein sequence)
Recommended Name: Arylsulfatase F precursor  
Size: 590 amino acids; 65940 Da
Cofactor: Binds 1 calcium ion per subunit (By similarity)
Secondary accessions: Q8TCC5

Explore the universe of human proteins at neXtProt for ARSF: NX_P54793

Explore proteomics data for ARSF at MOPED

Post-translational modifications: 

  • The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in
    prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity (By similarity)1
  • Glycosylation2 at Asn50, Asn117, Asn336
  • Selected DME Specific Peptides for ARSF (P54793) (see all 6)
     NGIYKGG  AFLTGRYP  HEFLFHYC  WEGGIRVPG 


    See ARSF Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001188467.1  NP_001188468.1  NP_004033.2  

    ENSEMBL proteins: 
     ENSP00000370519   ENSP00000352319   ENSP00000445594  
    Reactome Protein details: P54793

    ARSF Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for ARSF

    ARSF Antibody Products:

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    Cloud-Clone Corp. CLIAs for ARSF


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ARS: Arylsulfatase family

    4 InterPro protein domains:
     IPR017849 Alkaline_Pase-like_a/b/a
     IPR000917 Sulfatase
     IPR024607 Sulfatase_CS
     IPR017850 Alkaline_phosphatase_core

    Graphical View of Domain Structure for InterPro Entry P54793

    ProtoNet protein and cluster: P54793

    1 Blocks protein domain: IPB000917 Sulfatase

    UniProtKB/Swiss-Prot: ARSF_HUMAN, P54793
    Similarity: Belongs to the sulfatase family


    ARSF for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARSF_HUMAN, P54793
    Enzyme regulation: Not inhibited by DHEAS or warfarin
    Biophysicochemical properties: pH dependence: Optimum pH is 8;

         Genatlas biochemistry entry for ARSF:
    arylsulfatase F,X-linked,escaping inactivation,highly homologous to ARSC1,heat labile,not inhibited by warfarin

         Enzyme Numbers (IUBMB): EC 3.1.6.-1 EC 3.1.6.22 EC 3.1.62

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0004065arylsulfatase activity TAS9192838
    GO:0008484sulfuric ester hydrolase activity ----
    GO:0046872metal ion binding IEA--
         
    ARSF for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ARSF:
     Cell cycle / mitosis defect  Increased Salmonella enterica  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARSF
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARSF
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARSF

    miRNA
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    miRTarBase miRNAs that target ARSF:
    hsa-mir-335-5p (MIRT018415)

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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARSF

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARSF


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ARSF_HUMAN, P54793: Secreted (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endoplasmic reticulum4
    extracellular3
    lysosome3
    plasma membrane2
    cytosol1
    peroxisome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region ----
    GO:0005788endoplasmic reticulum lumen TAS--
    GO:0070062extracellular vesicular exosome IDA19056867

    ARSF for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ARSF About    
    See pathways by source

    SuperPathContained pathways About
    1Sphingolipid metabolism
    Sphingolipid metabolism0.61
    Glycosphingolipid metabolism0.56
    2Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    3PTM- gamma carboxylation, hypusine formation and arylsulfatase activation
    PTM- gamma carboxylation, hypusine formation and arylsulfatase activation0.31
    The activation of arylsulfatases0.00
    4Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
    Post-translational protein modification0.43
    Metabolism of proteins0.30

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    2 Reactome Pathways for ARSF
        Glycosphingolipid metabolism
    The activation of arylsulfatases



    ARSF for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARSF
    Interactions:

        Search GeneGlobe Interaction Network for ARSF

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    Selected Interacting proteins for ARSF (P547933 ENSP000003523194) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SNRNP70P086213, ENSP000002214484I2D: score=1 STRING: ENSP00000221448
    ARSAENSP000002161244STRING: ENSP00000216124
    ARSBENSP000002649144STRING: ENSP00000264914
    ARSDENSP000003705464STRING: ENSP00000370546
    ARSEENSP000003705264STRING: ENSP00000370526
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006665sphingolipid metabolic process TAS--
    GO:0006687glycosphingolipid metabolic process TAS--
    GO:0008152metabolic process ----
    GO:0043687post-translational protein modification TAS--
    GO:0044267cellular protein metabolic process TAS--

    ARSF for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARSF

    1 HMDB Compound for ARSF    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ARSF gene (3 alternative transcripts): 
    NM_001201538.1  NM_001201539.1  NM_004042.4  

    Unigene Cluster for ARSF:

    Arylsulfatase F
    Hs.101674  [show with all ESTs]
    Unigene Representative Sequence: BC022389
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000381127(uc022brz.1 uc004cre.2) ENST00000359361(uc004crf.2)
    ENST00000537104
    miRNA
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    GenScript: all cDNA clones in your preferred vector (see all 3): ARSF (NM_001201538)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARSF
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      QuantiTect SYBR Green Assays in human, mouse, rat ARSF
      QuantiFast Probe-based Assays in human, mouse, rat ARSF

    Additional mRNA sequence: 

    BC022389.1 X97868.1 

    3 DOTS entries:

    DT.40120125  DT.40120126  DT.100744166 

    18 AceView cDNA sequences:

    CD557574 NM_004042 BQ228278 BC022389 AI796044 AI471853 BV183280 BX107362 
    BI758861 X97868 BG432126 AI651169 H08174 AW612447 AI675063 AI245163 
    H08273 AW301236 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for ARSF    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11
    SP1:                                                                  
    SP2:                    -                                             


    ECgene alternative splicing isoforms for ARSF

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARSF expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTTCTTTT
    ARSF Expression
    About this image

    ARSF Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARSF Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.101674
        Custom PCR Arrays for ARSF
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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ARSF gene from Selected species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia ARSF1 arylsulfatase F 78.14(n)
    75.17(a)
      609908  XM_005641072.1  XP_005641129.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    42(a)
    many ↔ many
    GL344984.1(10017-16548)
    zebrafish
    (Danio rerio)
    Actinopterygii arsh6
    arylsulfatase H
    50(a)
    1 → many
    9(57794391-57813088) ENSDARG00000002299
    worm
    (Caenorhabditis elegans)
    Secernentea D1014.13
    sul-21
    arylsulfatase3
    sul-21
    47(a)3
    47.26(n)1
    41.01(a)1
      V(8160224-8161279)3
    1791941  NM_072701.31  NP_505102.11 


    ENSEMBL Gene Tree for ARSF (if available)
    TreeFam Gene Tree for ARSF (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARSF gene
    ARSI2  ARSJ2  ARSG2  ARSA2  STS2  ARSH2  ARSB2  GALNS2  
    ARSE2  ARSD2  
    5 SIMAP similar genes for ARSF using alignment to 1 protein entry:     ARSF_HUMAN:
    ARSD    ARSE    ARSH    STS    IDS

    ARSF for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ARSF
    PGOHUM00000233745


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARSF (see all 1535)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs603183001,2
    C,F--2929553(+) GGCGAC/GAGTAG 1 -- us2k11Minor allele frequency- G:0.00WA 2
    rs1397697621,2
    C--2929618(+) AGGATC/TGCTTG 1 -- us2k10--------
    rs587836351,2
    C--2929685(+) AATTCG/ATTTAA 1 -- us2k11Minor allele frequency- A:0.50WA 2
    rs59826361,2
    C--2929742(+) acatgC/Tctgta 1 -- us2k10--------
    rs1883098671,2
    --2929776(+) GGTGGA/GAGGAT 1 -- us2k10--------
    rs1510069441,2
    --2929817(+) GAGCTA/CTGACT 1 -- us2k10--------
    rs1930403151,2
    --2929840(+) TCCAGA/CCTGGG 1 -- us2k10--------
    rs1995652231,2
    --2929872(+) CAAAA-/TACTACTA 1 -- us2k10--------
    rs59826371,2
    C--2929889(+) TACTAA/CTAATA 1 -- us2k10--------
    rs601523331,2
    C,F--2929892(+) TACTAC/ATAATA 1 -- us2k11Minor allele frequency- A:0.50WA 2

    HapMap Linkage Disequilibrium report for ARSF (2958275 - 3030770 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for ARSF:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2752320CNV Gain17911159
    esv34985CNV Gain17911159
    dgv13n29CNV Gain16826518
    essv3621CNV CNV17122850
    dgv2432e1CNV Complex17122850

    Human Gene Mutation Database (HGMD): ARSF
    Locus Specific Mutation Databases (LSDB): ARSF

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ARSF
    DNA2.0 Custom Variant and Variant Library Synthesis for ARSF

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300003    OMIM disorders: --

    2 diseases for ARSF:    
    About MalaCards
    chondrodysplasia    tuberculosis


    ARSF for disorders           About GeneDecksing


    Export disorders for ARSF gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARSF gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with ARSF)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A cluster of sulfatase genes on Xp22.3: mutations in chondrodysplasia punctata (CDPX) and implications for warfarin embryopathy. (PubMed id 7720070)1, 2, 3 Franco B.... Ballabio A. (Cell 1995)
    2. Identification by shotgun sequencing, genomic organization, and functional analysis of a fourth arylsulfatase gene (ARSF) from the Xp22.3 region. (PubMed id 9192838)1, 2, 9 Puca A.A.... Franco B. (Genomics 1997)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    5. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    6. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (Nature 2005)
    9. Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (Genome Res. 2004)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 416 HGNC: 721 AceView: ARSF Ensembl:ENSG00000062096 euGenes: HUgn416
    ECgene: ARSF H-InvDB: ARSF

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ARSF Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ARSF gene:
    Search GeneIP for patents involving ARSF

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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