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Aliases for ARRDC5 Gene

Aliases for ARRDC5 Gene

  • Arrestin Domain Containing 5 2 3

External Ids for ARRDC5 Gene

Previous GeneCards Identifiers for ARRDC5 Gene

  • GC19M004843
  • GC19U900462
  • GC19M004844
  • GC19M004652

Summaries for ARRDC5 Gene

GeneCards Summary for ARRDC5 Gene

ARRDC5 (Arrestin Domain Containing 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARRDC5 Gene

Genomics for ARRDC5 Gene

Regulatory Elements for ARRDC5 Gene

Genomic Location for ARRDC5 Gene

4,890,437 bp from pter
4,902,867 bp from pter
12,431 bases
Minus strand

Genomic View for ARRDC5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARRDC5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARRDC5 Gene

Proteins for ARRDC5 Gene

  • Protein details for ARRDC5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Arrestin domain-containing protein 5
    Protein Accession:
    Secondary Accessions:

    Protein attributes for ARRDC5 Gene

    342 amino acids
    Molecular mass:
    38383 Da
    Quaternary structure:
    No Data Available
    • Sequence=EAW69191.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

neXtProt entry for ARRDC5 Gene

Proteomics data for ARRDC5 Gene at MOPED

Post-translational modifications for ARRDC5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARRDC5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ARRDC5 Gene

Domains for ARRDC5 Gene

Protein Domains for ARRDC5 Gene

Suggested Antigen Peptide Sequences for ARRDC5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the arrestin family.
  • Belongs to the arrestin family.
genes like me logo Genes that share domains with ARRDC5: view

No data available for Gene Families for ARRDC5 Gene

Function for ARRDC5 Gene

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARRDC5

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARRDC5 Gene

Localization for ARRDC5 Gene

Subcellular locations from

Jensen Localization Image for ARRDC5 Gene COMPARTMENTS Subcellular localization image for ARRDC5 gene
Compartment Confidence
cytosol 2
nucleus 2
cytoskeleton 1
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARRDC5 Gene

Pathways for ARRDC5 Gene

SuperPathways for ARRDC5 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ARRDC5 Gene


No data available for Pathways by source for ARRDC5 Gene

Transcripts for ARRDC5 Gene

mRNA/cDNA for ARRDC5 Gene

(6) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ARRDC5 Gene

Arrestin domain containing 5:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARRDC5

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARRDC5 Gene

No ASD Table

Relevant External Links for ARRDC5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ARRDC5 Gene

mRNA expression in normal human tissues for ARRDC5 Gene

mRNA differential expression in normal tissues according to GTEx for ARRDC5 Gene

This gene is overexpressed in Testis (28.7) and Whole Blood (6.8).

Protein differential expression in normal tissues for ARRDC5 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for ARRDC5 Gene

SOURCE GeneReport for Unigene cluster for ARRDC5 Gene Hs.574574

genes like me logo Genes that share expressions with ARRDC5: view

Expression partners for ARRDC5 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ARRDC5 Gene

Orthologs for ARRDC5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARRDC5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ARRDC5 35
  • 84.56 (n)
  • 81.9 (a)
  • 80 (a)
(Canis familiaris)
Mammalia ARRDC5 35
  • 84.56 (n)
  • 81.82 (a)
  • 78 (a)
(Mus musculus)
Mammalia Arrdc5 35
  • 74.68 (n)
  • 72.44 (a)
Arrdc5 16
Arrdc5 36
  • 70 (a)
(Pan troglodytes)
Mammalia ARRDC5 35
  • 98.93 (n)
  • 97.95 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Arrdc5 35
  • 75 (n)
  • 74.68 (a)
(Gallus gallus)
Aves LOC101752017 35
  • 58.04 (n)
  • 49.65 (a)
Species with no ortholog for ARRDC5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ARRDC5 Gene

Gene Tree for ARRDC5 (if available)
Gene Tree for ARRDC5 (if available)

Paralogs for ARRDC5 Gene

No data available for Paralogs for ARRDC5 Gene

Variants for ARRDC5 Gene

Sequence variations from dbSNP and Humsavar for ARRDC5 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs2297506 -- 4,891,227(-) CAGCA(C/T)GCAGG reference, missense
rs2602694 -- 4,890,317(-) TAACA(C/T)GGTGA downstream-variant-500B
rs2602703 -- 4,898,655(+) tcAGG(C/T)GGGCT intron-variant
rs2656931 -- 4,899,765(-) ttttt(A/T)gtaga intron-variant, upstream-variant-2KB
rs2656932 -- 4,897,069(-) TGAGG(C/T)AGGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ARRDC5 Gene

Variant ID Type Subtype PubMed ID
nsv470117 CNV Loss 18288195
nsv910860 CNV Loss 21882294
nsv910862 CNV Loss 21882294
esv25954 CNV Gain 19812545
nsv910863 CNV Loss 21882294
dgv3682n71 CNV Loss 21882294

Relevant External Links for ARRDC5 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARRDC5 Gene

Disorders for ARRDC5 Gene

No disorders were found for ARRDC5 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ARRDC5 Gene

Publications for ARRDC5 Gene

  1. Polyserase-I, a human polyprotease with the ability to generate independent serine protease domains from a single translation product. (PMID: 12886014) Cal S. … Lopez-Otin C. (Proc. Natl. Acad. Sci. U.S.A. 2003) 2 3
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4

Products for ARRDC5 Gene

Sources for ARRDC5 Gene

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