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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARR3 Gene

protein-coding   GIFtS: 56
GCID: GC0XP069488

arrestin 3, retinal (X-arrestin)
 Explore 12 diseases affiliated with
ARR3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for ARR3    

Aliases
for ARR3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Arrestin 3, Retinal (X-Arrestin)1 2     X-Arrestin1
ARRX1 2 3     CArr1
Cone Arrestin2 3     Arrestin 42
Retinal Cone Arrestin-32 3     Arrestin-C1
C-Arrestin1     CAR3

External Ids:    HGNC: 7101   Entrez Gene: 4072   Ensembl: ENSG000001205007   OMIM: 3017705   UniProtKB: P365753   

Export aliases for ARR3 gene to outside databases

Previous GC identifers: GC0XP065666 GC0XP066965 GC0XP067721 GC0XP068354 GC0XP069271 GC0XP069404 GC0XP063309


Summaries
for ARR3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: ARRC_HUMAN, P36575
Function: May play a role in an as yet undefined retina-specific signal transduction. Could binds to
photoactivated-phosphorylated red/green opsins

Gene Wiki entry for ARR3


Genomic Views
for ARR3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011669.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARR3 gene promoter:
         AP-2alpha isoform 3   AP-2alpha isoform 2   Tal-1beta   E2F-1   E2F   ARP-1   AP-2alpha isoform 4   AP-2alpha   ITF-2   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ARR3 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARR3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARR3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xcen-q21   Ensembl cytogenetic band:  Xq13.1   HGNC cytogenetic band: Xq

ARR3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARR3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP069488:  view genomic region     (about GC identifiers)

Start:
 69,488,155 bp from pter      End:
 69,501,690 bp from pter
Size:
 13,536 bases      Orientation:
 plus strand

Proteins
for ARR3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: ARRC_HUMAN, P36575 (See protein sequence)
Recommended Name: Arrestin-C  
Size: 388 amino acids; 42778 Da
Subunit: Interacts with CXCR4; the interaction is dependent on the C-terminal phosphorylation of CXCR4 and modulates
the calcium ion mobilization activity of CXCR4
2 PDB 3D structures from and Proteopedia for ARR3:
1XEH (3D)        2A34 (3D)    
Secondary accessions: B5B0B9 Q5JT23 Q5JT24 Q6IBF5 Q96EN2
Alternative splicing: 2 isoforms:  P36575-1   P36575-2   

Explore the universe of human proteins at neXtProt for ARR3: NX_P36575

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P36575

    • ARR3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004303.2  
    ENSEMBL proteins: 
     ENSP00000363619   ENSP00000425505   ENSP00000311538  

    Human Recombinant Protein Products: 
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    Novus Biologicals ARR3 Proteins
    Novus Biologicals ARR3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for ARR3

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001750photoreceptor outer segment IEA--
    GO:0005625soluble fraction ----
    GO:0005737cytoplasm TAS8224247
    GO:0045202synapse IEA--


    ARR3 for ontologies           About GeneDecksing



    ARR3 Antibody Products: 
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    ThermoFisher Antibodies for ARR3

    Assay Products for ARR3: 
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    Uscn ELISAs and CLIAs for ARR3

    Protein Domains /
    Families
    for ARR3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    ARR3 for domains           About GeneDecksing

    5/7 InterPro domains/families (see all 7):
     IPR000698 Arrestin
     IPR014756 Ig_E-set
     IPR014752 Arrestin_C
     IPR011022 Arrestin_C-like
     IPR011021 Arrestin-like_N

    Graphical View of Domain Structure for InterPro Entry P36575

    ProtoNet protein and cluster: P36575

    1 Blocks protein family: IPB000698 Arrestin

    UniProtKB/Swiss-Prot: ARRC_HUMAN, P36575
    Similarity: Belongs to the arrestin family


    Function
    for ARR3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: ARRC_HUMAN, P36575
    Function: May play a role in an as yet undefined retina-specific signal transduction. Could binds to
    photoactivated-phosphorylated red/green opsins

         Genatlas biochemistry entry for ARR3:
    X arrestin,expressed in the red-,green-,blue-sensitive cone photoreceptors modulator of cone phototransduction

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARR3
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    SwitchGear 3'UTR luciferase reporter plasmid: ARR3 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARR3 (see all 4)
    OriGene shRNA RFP: ARR3
    OriGene siRNA: ARR3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARR3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for ARR3

    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for ARR3

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARR3

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002046opsin binding IEA--
    GO:0005515protein binding IPI16189514
    GO:0019904protein domain specific binding ----
    GO:0051219phosphoprotein binding IEA--


    ARR3 for ontologies           About GeneDecksing


    Animal Models:
         1 MGI mutant phenotype (inferred from 1 allele) (MGI details for Arr3):
     vision/eye 

    ARR3 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for ARR3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Visual Cycle in Retinal Rods
    		Visual Cycle in Retinal Rods1.00
    2Thromboxane A2 receptor signaling
    		Thromboxane A2 receptor signaling1.00
    3CXCR4-mediated signaling events
    		CXCR4-mediated signaling events1.00
    4Visual signal transduction- Rods
    		Visual signal transduction- Cones0.39

    1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ARR3
        Visual Cycle in Retinal Rods

    3 BioSystems Pathways for ARR3 
        Thromboxane A2 receptor signaling
    CXCR4-mediated signaling events
    Visual signal transduction- Cones


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARR3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/38 Interacting proteins for ARR3 (P365751, 2, 3 ENSP000003115384) via UniProtKB, MINT, STRING, and/or I2D (see all 38)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CAPNS1P046322, 3, ENSP000002465334MINT-64400 I2D: score=5 STRING: ENSP00000246533
    RNASE6Q930912, 3, ENSP000003020464MINT-64402 I2D: score=5 STRING: ENSP00000302046
    MAP2K7O147332, 3, ENSP000003810664MINT-64399 I2D: score=4 STRING: ENSP00000381066
    ZNF496Q96IT11, 2, 3, ENSP000002947534EBI-718116,EBI-743906 MINT-67526 I2D: score=6 STRING: ENSP00000294753
    OPN1MWP040013, ENSP000003589514I2D: score=1 STRING: ENSP00000358951
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001932regulation of protein phosphorylation IEA--
    GO:0006897endocytosis IEA--
    GO:0007165signal transduction IEA--
    GO:0007601visual perception IEA--


    ARR3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for ARR3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ARR3 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARR3
    4 Novoseek chemical compound relationships for ARR3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 42.3 60 9144337 (3), 11350736 (3), 14623314 (2), 12970324 (2) (see all 18)
    threonine 8.91 1 9694886 (1)
    retinoic acid 7.31 5 11980849 (2), 12601020 (1)
    arachidonic acid 5.7 1 9144337 (1)

    Search CenterWatch for drugs/clinical trials and news about ARR3 / ARRC 

    Transcripts
    for ARR3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for ARR3 gene: 
    NM_004312.2  

    Unigene Cluster for ARR3:

    Arrestin 3, retinal (X-arrestin)
    Hs.308  [show with all ESTs]
    Unigene Representative Sequence: NM_004312
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374495(uc004dya.3) ENST00000477379 ENST00000480877 ENST00000307959(uc004dyb.2)


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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARR3
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    Inhib. RNA
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    OriGene shRNA RFP: ARR3
    OriGene siRNA: ARR3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARR3
    Clone
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARR3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARR3

    Additional cDNA sequence: 

    AF033105.1 BC012096.1 CR456849.1 EU883571.1 U03626.1 

    3 DOTS entries:

    DT.440760  DT.95363472  DT.87046551 

    24/26 AceView cDNA sequences (see all 26):

    BU740536 BM713285 BM707744 BU733263 BU165421 BC012096 BM714746 BM676400 
    BM725277 CR456849 BG472156 U03626 NM_004312 AW954890 BM722855 AF033105 
    AA047869 AA019125 AL712046 AA053939 H38026 AA019124 AA317479 BQ637477 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for ARR3    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10
    SP1:                                -                                             
    SP2:                    -           -                                             
    SP3:                                                                              
    SP4:                                                                              


    ECgene alternative splicing isoforms for ARR3

    Expression
    for ARR3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARR3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGCCGCTAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    ARR3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    5 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeOuter Nuclear LayerMature L Cone CellsPhotoreceptors, Retina
    EyeOuter Nuclear LayerMature M Cone CellsPhotoreceptors, Retina
    EyeOuter Nuclear LayerMature M-S Cone CellsPhotoreceptors, Retina
    EyeOuter Nuclear LayerMature S Cone CellsPhotoreceptors, Retina
    EyeOuter Nuclear LayerCone Precursor CellsPhotoreceptors, Retina
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    Photoreceptor-like cells (Differentiation of h...)
    Photoreceptor-like cells (Generation of retina...)Eye
    Photoreceptor-like cells (Generation of retina...)

    See ARR3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARR3

    SOURCE GeneReport for Unigene cluster: Hs.308

    UniProtKB/Swiss-Prot: ARRC_HUMAN, P36575
    Tissue specificity: Inner and outer segments, and the inner plexiform regions of the retina

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARR3

    Orthologs
    for ARR3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for ARR3 gene from 6/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Arr31 , 5 arrestin 3, retinal1, 5 85.65(n)1
    83.69(a)1    		   X (43.72 cM)5
    1707351  NM_133205.31  NP_573468.11 
     1006054975 
    chicken
    (Gallus gallus)    		 Aves ARR31 arrestin 3, retinal 71.53(n)
    69.53(a)    		   769109  NM_001097533.1  NP_001091002.1 
    lizard
    (Anolis carolinensis)    		 Reptilia ARR36
    		 --
    		 62(a)
    		 1 ↔ 1
    		 GL344027.1(4609-18806)
    zebrafish
    (Danio rerio)    		 Actinopterygii arr3a1 arrestin 3a, retinal (X-arrestin) 64.18(n)
    60.74(a)    		   436678  NM_001002405.1  NP_001002405.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta Arr13 deactivation of rhodopsin mediated signaling
    metarhodopsin more    		 41(a)
    (best of 2)    		   36D3   --
    worm
    (Caenorhabditis elegans)    		 Secernentea arr-16
    		 Probable beta-arrestin
    		 40(a)
    		 1 → many
    		 X(950779-954230)


    ENSEMBL Gene Tree for ARR3 (if available)
    TreeFam Gene Tree for ARR3 (if available) 

    Paralogs
    for ARR3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARR3 gene
    SAG2  ARRB22  ARRB12  
    6 SIMAP similar genes for ARR3 using alignment to 2 protein entries:     ARRC_HUMAN (see all proteins):
    ARRB1    ARRB2    DKFZp686I1383    DKFZp686J1593    SAG    DKFZp686L0365

    ARR3 for paralogs           About GeneDecksing



    Genomic Variants
    for ARR3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/209 NCBI SNPs in ARR3 are shown (see all 209)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs59368701,2
    		C,F,A,H,--69486376(+) ATTCAT/CTGAGC 1 -- us2k17Minor allele frequency- C:0.27NS EA NA CSA 423
    rs1388876061,2
    		--69486528(+) AGTAGA/GAAGAG 1 -- us2k10--------
    rs9464511,2
    		C,--69486614(-) AATGAC/TTAGTG 1 -- us2k18Minor allele frequency- T:0.00WA NA CSA 12
    rs1503891161,2
    		--69486737(+) TGACTC/TTTCGC 1 -- us2k10--------
    rs726288641,2
    		--69486740(+) CTTTTC/TGCCTT 1 -- us2k10--------
    rs1380246381,2
    		--69486742(+) TTTCGC/TCTTCC 1 -- us2k10--------
    rs1841677891,2
    		--69486749(+) TTCCTC/TGCAGA 1 -- us2k10--------
    rs1888655631,2
    		--69486847(+) TGCACC/TATCTG 1 -- us2k10--------
    rs1909005911,2
    		--69486882(+) ATAGTA/GACTAA 1 -- us2k10--------
    rs1825840821,2
    		--69486897(+) CCAGGA/CCCTGA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARR3 (69488155 - 69501690 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ARR3: --

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    Disorders / Diseases
    for ARR3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    ARR3 for disorders           About GeneDecksing

    OMIM gene information: 301770    OMIM disorders: --

    12 diseases for ARR3:    About MalaCards
    retinitis    leber congenital amaurosis    parathyroid adenoma    retinitis pigmentosa
    retinal vasculitis    vasculitis    retinal degeneration    behcet's disease
    retinoblastoma    adenoma    breast cancer    neuronitis

    2 Novoseek disease relationships for ARR3 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinoblastoma 31.7 6 11980849 (2), 15363854 (2), 12601020 (1)
    tumors 4.5 1 12970324 (1)


    Export disorders for ARR3 gene to outside databases

    Publications
    for ARR3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARR3 gene, integrated from 9 sources (see all 79):
    (articles sorted by number of sources associating them with ARR3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. X-arrestin: a new retinal arrestin mapping to the X chromosome. (PubMed id 8224247)1, 2, 3, 9 Murakami A.... Inana G. (1993)
    2. Cone arrestin identified by targeting expression of a functional family. (PubMed id 8308033)1, 2, 9 Craft C.M.... Wiechmann A.F. (1994)
    3. Isolation and characterization of the human X-arrestin gene. (PubMed id 9931451)1, 2, 9 Sakuma H.... Inana G. (1998)
    4. Immunolocalization of X-arrestin in human cone photoreceptors. (PubMed id 8612728)1, 2, 9 Sakuma H.... McLaren M.J. (1996)
    5. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Identification and light-dependent translocation of a cone-specific antigen, cone arrestin, recognized by monoclonal antibody 7G6. (PubMed id 12824223)1, 9 Zhang H....Baehr W. (2003)
    8. Cone arrestin binding to JNK3 and Mdm2: conformational preference and localization of interaction sites. (PubMed id 17680991)1, 9 Song X....Gurevich V.V. (2007)
    9. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. (PubMed id 17620599)1, 9 Xiao K....Lefkowitz R.J. (2007)
    10. Loss of cone molecular markers in rhodopsin-mutant human retinas with retinitis pigmentosa. (PubMed id 11063754)1, 9 John S.K....Milam A.H. (2000)

    External Searches for ARR3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing ARR3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 407 HGNC: 710 AceView: ARR3 Ensembl:ENSG00000120500 euGenes: HUgn407
    ECgene: ARR3 H-InvDB: ARR3

    Other Databases showing ARR3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing ARR3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARR3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for ARR3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for ARR3 gene:
    Search GeneIP for patents involving ARR3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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