Aliases for ARPP21 Gene
External Ids for ARPP21 Gene
This gene encodes a cAMP-regulated phosphoprotein. The encoded protein is enriched in the caudate nucleus and cerebellar cortex. A similar protein in mouse may be involved in regulating the effects of dopamine in the basal ganglia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]
GeneCards Summary for ARPP21 Gene
ARPP21 (CAMP-Regulated Phosphoprotein, 21kDa) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and calmodulin binding. An important paralog of this gene is R3HDM1.
UniProtKB/Swiss-Prot for ARPP21 Gene
Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons.