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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARPP19 Gene

protein-coding   GIFtS: 51
GCID: GC15M052839

CAMP-Regulated Phosphoprotein, 19kDa

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CAMP-Regulated Phosphoprotein, 19kDa1 2     ARPP-162
ARPP-192 3     ENSAL2
ARPP162 5     CAMP-Regulated Phosphoprotein 192
Endosulfine Alpha-Like1     Cyclic AMP Phosphoprotein, 19 KD2

External Ids:    HGNC: 169671   Entrez Gene: 107762   Ensembl: ENSG000001289897   OMIM: 6054875   UniProtKB: P562113   

Export aliases for ARPP19 gene to outside databases

Previous GC identifers: GC15M050627 GC15M029670


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARPP19 Gene:
The 19-kD cAMP-regulated phosphoprotein plays a role in regulating mitosis by inhibiting protein phosphatase-2A
(PP2A; see MIM 176915) (summary by Gharbi-Ayachi et al., 2010 (PubMed 21164014)).(supplied by OMIM, Feb 2011)

GeneCards Summary for ARPP19 Gene: 
ARPP19 (cAMP-regulated phosphoprotein, 19kDa) is a protein-coding gene. Diseases associated with ARPP19 include folliculitis, and papillary thyroid carcinoma, and among its related super-pathways are Mitotic M-M/G1 phases and Cell Cycle, Mitotic. GO annotations related to this gene include potassium channel regulator activity and receptor binding. An important paralog of this gene is ENSA.

UniProtKB/Swiss-Prot: ARP19_HUMAN, P56211
Function: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.
When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its
activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M
phase. May indirectly enhance GAP-43 expression

Gene Wiki entry for ARPP19 (ARPP-19) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000015.9  NT_010194.17  NC_018926.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARPP19 gene promoter:
         Sox5   AML1a   Cdc5   HNF-1A   Evi-1   FOXL1   POU2F1   HNF-1   POU2F1a   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ARPP19 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARPP19

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARPP19


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21.2   Ensembl cytogenetic band:  15q21.2   HGNC cytogenetic band: 15q11.2

ARPP19 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARPP19 gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M052839:  view genomic region     (about GC identifiers)

Start:
52,839,242 bp from pter      End:
52,862,080 bp from pter
Size:
22,839 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARP19_HUMAN, P56211 (See protein sequence)
Recommended Name: cAMP-regulated phosphoprotein 19  
Size: 112 amino acids; 12323 Da
Subunit: Interacts (when phosphorylated at Ser-62) with PPP2R2D (By similarity). Interacts with SNCA
Subcellular location: Cytoplasm (By similarity)
Secondary accessions: B2R497 Q6IAM2 Q86TA6 Q9UD70
Alternative splicing: 2 isoforms:  P56211-1   P56211-2   (Contains a N-acetylmethionine at position 1 (By similarity))

Explore the universe of human proteins at neXtProt for ARPP19: NX_P56211

Explore proteomics data for ARPP19 at MOPED 

Post-translational modifications:

  • UniProtKB: Phosphorylation at Ser-62 by GWL during mitosis is essential for interaction with PPP2R2D (PR55-delta) and
    subsequent inactivation of PP2A (By similarity). Phosphorylated by PKA
  • UniProtKB: Isoform ARPP-16 contains a N-acetylmethionine at position 1 (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P56211

  • ARPP19 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARPP19 Protein Expression
    REFSEQ proteins: NP_006619.1  
    ENSEMBL proteins: 
     ENSP00000455625   ENSP00000249822   ENSP00000454234   ENSP00000457805   ENSP00000455986  
     ENSP00000455151   ENSP00000455610   ENSP00000454297   ENSP00000454612   ENSP00000457631  
     ENSP00000454341   ENSP00000457123  
    Reactome Protein details: P56211
    Human Recombinant Protein Products for ARPP19: 
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    Novus Biologicals ARPP19 Proteins
    Novus Biologicals ARPP19 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ARPP19 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005654nucleoplasm TAS--
    GO:0005737cytoplasm IEA--

    ARPP19 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR006760 Endosulphine

    Graphical View of Domain Structure for InterPro Entry P56211

    ProtoNet protein and cluster: P56211

    1 Blocks protein domain: IPB006760 cAMP-regulated phosphoprotein/endosulfine conserved region

    UniProtKB/Swiss-Prot: ARP19_HUMAN, P56211
    Similarity: Belongs to the endosulfine family


    ARPP19 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARP19_HUMAN, P56211
    Function: Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis.
    When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its
    activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M
    phase. May indirectly enhance GAP-43 expression
    Induction: Expression may be regulated by miR-451

         Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004864protein phosphatase inhibitor activity IEA--
    GO:0005102receptor binding IDA9653196
    GO:0008601protein phosphatase type 2A regulator activity ISS--
    GO:0015459potassium channel regulator activity IDA9653196
    GO:0019212phosphatase inhibitor activity ISS--
         
    ARPP19 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for ARPP19:
     Increased cell number in G1, a 

         1 MGI phenotypic allele for Arpp19 (no phenotypes)

    ARPP19 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Arpp19tm1Lex for ARPP19

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARPP19 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ARPP19

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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for ARPP19 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1M Phase
    M Phase0.88
    Mitotic M-M/G1 phases0.88
    2Cell Cycle
    Cell Cycle, Mitotic0.84
    Cell Cycle0.84
    3Regulation of Glucokinase by Glucokinase Regulatory Protein
    Mitotic Prophase0.70
    4DNA Damage
    Cell Cycle / Checkpoint Control0.32
    5ERK/MAPK targets
    MASTL Facilitates Mitotic Progression0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for ARPP19
        Cell Cycle / Checkpoint Control

    5/6        Reactome Pathways for ARPP19 (see all 6)
        Mitotic Prophase
    Cell Cycle
    M Phase
    MASTL Facilitates Mitotic Progression
    Mitotic M-M/G1 phases



    ARPP19 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARPP19

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for ARPP19 (P562113 ENSP000002498224) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKGQ9Y6K93, ENSP000003586224I2D: score=1 STRING: ENSP00000358622
    PRKCGP051293I2D: score=2 
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000086G2/M transition of mitotic cell cycle IMP--
    GO:0000278mitotic cell cycle TAS--
    GO:0007067mitosis IMP--
    GO:0045722positive regulation of gluconeogenesis IDA9653196
    GO:0046326positive regulation of glucose import NAS9653196

    ARPP19 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARPP19 (ARP19)

    Search CenterWatch for drugs/clinical trials and news about ARPP19 / ARP19

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARPP19 gene: 
    NM_006628.4  

    Unigene Cluster for ARPP19:

    CAMP-regulated phosphoprotein, 19kDa
    Hs.512908  [show with all ESTs]
    Unigene Representative Sequence: AL833077
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000566423(uc002ace.1) ENST00000249822(uc002acd.1) ENST00000561650
    ENST00000568196 ENST00000563277 ENST00000567669 ENST00000569723 ENST00000569281
    ENST00000564163 ENST00000563566 ENST00000561971 ENST00000565288 ENST00000567830


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    8/107 QIAGEN miScript miRNA Assays for microRNAs that regulate ARPP19 (see all 107):
    hsa-miR-4272 hsa-miR-15a hsa-miR-1304 hsa-miR-3116 hsa-miR-92b hsa-miR-490-5p hsa-miR-4324 hsa-miR-34c-5p
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    Additional mRNA sequence: 

    AF084555.1 AJ223091.1 AK023195.1 AK123616.1 AK311751.1 AL833077.2 BC003418.1 BC100015.1 
    CR457132.1 

    24/28 DOTS entries (see all 28):

    DT.100827137  DT.99985665  DT.92453292  DT.91834623  DT.92453299  DT.100827145  DT.100030805  DT.100722936 
    DT.100827134  DT.95164972  DT.121013627  DT.121013571  DT.97860182  DT.121013610  DT.121013626  DT.92453298 
    DT.100827139  DT.75103115  DT.91854733  DT.432747  DT.100827135  DT.100827138  DT.121013605  DT.121013616 

    24/499 AceView cDNA sequences (see all 499):

    AL598197 BE349354 CA392820 CB069364 CA394001 AV728861 AI920792 AA731928 
    BM762356 BM468300 CF454665 BX331775 CB136273 BU902230 BF794225 BP349864 
    F08459 CB960738 BM745515 BM766460 BM463383 N70624 AV715598 AA290856 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for ARPP19 (see all 11)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g · 6h · 6i
    SP1:                                -     -           -           -                                                               
    SP2:                                -     -           -     -     -                                                               
    SP3:                                -     -           -     -     -                                                               
    SP4:                                -     -     -     -           -                                                               
    SP5:                                -     -           -     -     -                                                               


    ECgene alternative splicing isoforms for ARPP19

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARPP19 expression in normal human tissues (normalized intensities)      ARPP19 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGCATTAACT
    ARPP19 Expression
    About this image


    ARPP19 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/1 selected tissues (see all 1) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Medulla Oblongata
             Caudate nucleus   

    See ARPP19 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARPP19

    SOURCE GeneReport for Unigene cluster: Hs.512908
        SABiosciences Custom PCR Arrays for ARPP19
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARPP19

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARPP19 gene from 6/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arpp191 , 5 cAMP-regulated phosphoprotein 191, 5 91.07(n)1
    99.11(a)1
      9 (42.25 cM)5
    590461  NM_001142655.11  NP_001136127.11 
     750376145 
    chicken
    (Gallus gallus)
    Aves ARPP191 cAMP-regulated phosphoprotein, 19kDa 85.42(n)
    97.32(a)
      768853  NM_001081707.1  NP_001075176.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Arpp192 similar to cyclic AMP phosphoprotein, 19 kD 77.85(n)    BC045060.1 
    zebrafish
    (Danio rerio)
    Actinopterygii arpp19a1 cAMP-regulated phosphoprotein 19a 71.11(n)
    77.14(a)
      393603  NM_200630.1  NP_956924.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta endos6
    endosulfine
    41(a)
    1 → many
    3L(14022679-14024806)
    worm
    (Caenorhabditis elegans)
    Secernentea ensa-16
    Protein ENSA-1
    21(a)
    1 → many
    I(9850020-9851793)


    ENSEMBL Gene Tree for ARPP19 (if available)
    TreeFam Gene Tree for ARPP19 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARPP19 gene
    ENSA2  
    1 SIMAP similar gene for ARPP19 using alignment to 4 protein entries:     ARP19_HUMAN (see all proteins):
    ENSA

    ARPP19 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for ARPP19
    PGOHUM00000240817 PGOHUM00000251404


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/533 SNPs in ARPP19 are shown (see all 533)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs667785861,2
    C--32912654(-) TATTA-/TCTGTTT 1 -- int12Minor allele frequency- TC:0.25NA 4
    rs358845931,2
    C--32914368(+) TAAAA-/AC/C  
            
    ACAGT
    1 -- int10--------
    rs1883301191,2
    --52838961(+) ATGCAA/GGAGTC 1 -- ds50010--------
    rs757464871,2
    C,F--52838973(+) GTGGTG/AAGAAT 1 -- ds50011Minor allele frequency- A:0.02NA 120
    rs341972421,2
    C,F,H--52838988(+) ACTTCT/CGGCAA 1 -- ds500117Minor allele frequency- C:0.18NS EA NA 2224
    rs1401272491,2
    C--52838991(+) TCTGGA/CAATCA 1 -- ds50010--------
    rs1498123451,2
    --52839003(+) TCATTC/TAATCT 1 -- ds50010--------
    rs584357241,2
    C--52839295(+) AATGC-/AAAAAA 1 -- ds50011Minor allele frequency- A:0.00CSA 2
    rs596684471,2
    C--52839310(+) AAAAA-/A/AA  
            
    TCAAA
    1 -- ds50011NA 2
    rs31796581,2
    C--52839437(-) AATTTC/TTATTG 1 -- ut312Minor allele frequency- T:0.00NA 4

    HapMap Linkage Disequilibrium report for ARPP19 (52839242 - 52862080 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ARPP19:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1001541CNV Gain20482838
    nsv471245CNV Gain18288195
    nsv833006CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605487    OMIM disorders: --

    5 diseases for ARPP19:    About MalaCards
    folliculitis    papillary thyroid carcinoma    down syndrome    thyroiditis
    alzheimer's disease


    ARPP19 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for ARPP19 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARPP19 gene, integrated from 9 sources (see all 28):
    (articles sorted by number of sources associating them with ARPP19)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A. (PubMed id 21164014)1, 2 Gharbi-Ayachi A.... Lorca T. (2010)
    2. Conformation-specific binding of alpha-synuclein to no vel protein partners detected by phage display and NMR spectroscopy. (PubMed id 17893145)1, 2 Woods W.S....George J.M. (2007)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. ARPP-16/ARPP-19: a highly conserved family of cAMP-regulated phosphoproteins. (PubMed id 11279279)1, 3 Dulubova I....Nairn A.C. (2001)
    6. Identification of okadaic-acid-induced genes by mRNA differential display in glioma cells. (PubMed id 10754390)1, 2 Chin L.S.... Murray S.F. (2000)
    7. Human alpha-endosulfine, a possible regulator of sulfonylurea- sensitive K(ATP) channel: molecular cloning, expression and biological properties. (PubMed id 9653196)1, 2 Heron L.... Bataille D. (1998)
    8. Alpha endosulfine is a novel molecule, structurally related to a family of phosphoproteins. (PubMed id 8687439)1, 3 Peyrollier K....Bataille D. (1996)
    9. Expression of mRNAs encoding ARPP-16/19, ARPP-21, and DARPP-32 in human brain tissue. (PubMed id 8120638)1, 2 Brene S.... Persson H. (1994)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10776 HGNC: 16967 AceView: ARPP-19 Ensembl:ENSG00000128989 euGenes: HUgn10776
    ECgene: ARPP19 H-InvDB: ARPP19

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARPP19 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARPP19 gene:
    Search GeneIP for patents involving ARPP19

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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