ARPC2 Gene
protein-coding GIFtS: 63
GCID: GC02P219081
|
|
actin related protein 2/3 complex, subunit 2, 34kDa(Previous names: actin related protein 2/3 complex, subunit 2 (34 kD) )
| |
Aliases
for ARPC2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Actin Related Protein 2/3 Complex, Subunit 2, 34kDa1 2 | | PNAS-1392 | | ARC341 2 3 5 | | Actin-Related Protein 2/3 Complex Subunit 22 | | P34-Arc1 | | ARP2/3 Protein Complex Subunit 342 | | Arp2/3 Complex 34 KDa Subunit2 3 | | P34-ARC1 | | Actin Related Protein 2/3 Complex, Subunit 2 (34 KD)1 | | |
Export aliases for ARPC2 gene to outside databasesPrevious GC identifers: GC02P217097 GC02P217803 GC02P219045 GC02P219284 GC02P218907 GC02P218790 GC02P210935 |
Summaries
for ARPC2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARPC2:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has beenimplicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role ofthe protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants havebeen characterized to date. Additional alternatively spliced variants have been described but their full length naturehas not been determined. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ARPC2_HUMAN, O15144Function: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actinpolymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branchedactin networks. Seems to contact the mother actin filament
Gene Wiki entry for ARPC2
|
Genomic Views
for ARPC2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000002.11 NC_018913.1 NT_005403.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARPC2 gene promoter:
FOXF2 RelA NF-kappaB NF-kappaB1 LCR-F1
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARPC2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARPC2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q36.1 Ensembl cytogenetic band: 2q35 HGNC cytogenetic band: 2q36.1ARPC2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02P219081: view genomic region
(about GC identifiers)
Start:
|
219,081,817 bp from pter |
End:
|
219,119,079 bp from pter |
Size:
|
37,263 bases |
Orientation:
|
plus strand |
|
Proteins
for ARPC2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ARPC2_HUMAN, O15144 (See
protein sequence)Recommended Name: Actin-related protein 2/3 complex subunit 2 Size: 300 amino acids; 34333 Da
Subunit: Component of the Arp2/3 complex composed of ARP2, ARP3, ARPC1B/p41-ARC, ARPC2/p34-ARC, ARPC3/p21-ARC,ARPC4/p20-ARC and ARPC5/p16-ARC
Subcellular location: Cytoplasm, cytoskeleton. Cell projection
Sequence caution: Sequence=AAC50874.1; Type=Frameshift; Positions=14; Sequence=AAF71122.1; Type=Erroneous initiation;
Secondary accessions: Q92801 Q9P1D4Explore the universe of human proteins at neXtProt for ARPC2: NX_O15144
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15144
ARPC2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_005722.1 NP_690601.1
ENSEMBL proteins: ENSP00000327137 ENSP00000401070 ENSP00000396475 ENSP00000412632 ENSP00000295685 ENSP00000411612 Reactome Protein details: O15144
Human Recombinant Protein Products:
Gene Ontology (GO): 5/10 cellular component terms (GO ID links to tree view) (see all 10): About this table
ARPC2 for ontologies About GeneDecksing
ARPC2 Antibody Products:
Assay Products for ARPC2: |
Protein
Domains /
Families
for ARPC2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARPC2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O15144ProtoNet protein and cluster: O15144 1 Blocks protein family: IPB007188 Arp2/3 complex
UniProtKB/Swiss-Prot: ARPC2_HUMAN, O15144Similarity: Belongs to the ARPC2 family |
Function
for ARPC2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ARPC2_HUMAN, O15144Function: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actinpolymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branchedactin networks. Seems to contact the mother actin filament Genatlas biochemistry entry for ARPC2:actin related protein 2/3 complex,subunit 2 (34kDa),localized to the lamellipodia of stationary and locomotingfibroblasts,inducing actin polymerization and potentially participating in lamellipodial protrusion
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARPC2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARPC2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ARPC2 (NM_005731) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARPC2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARPC2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARPC2 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
ARPC2 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for ARPC2:
Animal Models:
5 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Arpc2):
ARPC2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ARPC2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/16 super-pathways (see all 16) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell adhesion_Integrin-mediated cell adhesion and migration | | | 2 | G-protein signaling_RAC1 in cellular process | | | 3 | Regulation of actin dynamics for phagocytic cup formation | | | 4 | Cytoskeleton remodeling Slit-Robo signaling | | | 5 | Immune response CD16 signaling in NK cells | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/13 EMD Millipore Pathways for ARPC2 (see all 13)
5/14  GeneGo (Thomson Reuters) Pathways for ARPC2 (see all 14)
5  BioSystems Pathways for ARPC2
5/6 
Reactome Pathways for ARPC2 (see all 6)
5 
Kegg Pathways (Kegg details for ARPC2):
ARPC2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARPC2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/139 Interacting proteins for ARPC2 (O151441, 2, 3 ENSP000002956854) via UniProtKB, MINT, STRING, and/or I2D (see all 139)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006928 | cellular component movement |
TAS | 9230079 | | GO:0030833 | regulation of actin filament polymerization |
-- | -- | | GO:0030838 | positive regulation of actin filament polymerization |
IEA | -- | | GO:1900026 | positive regulation of substrate adhesion-dependent cell spreading |
IEA | -- |
ARPC2 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARPC2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ARPC2
2 DrugBank Compounds for ARPC2 About this table
Search CenterWatch for drugs/clinical trials and news about ARPC2
|
Transcripts
for ARPC2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARPC2 gene (2 alternative transcripts): NM_005731.2 NM_152862.1 Unigene Cluster for ARPC2: Actin related protein 2/3 complex, subunit 2, 34kDa Hs.529303 [show with all ESTs]Unigene Representative Sequence: BF24073418 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000315717(uc002vhd.3) ENST00000420104 ENST00000489598 ENST00000491780
ENST00000420201 ENST00000478612 ENST00000480062 ENST00000414983 ENST00000295685(uc002vhe.3)
ENST00000465395 ENST00000471355 ENST00000472753 ENST00000484961 ENST00000470146
ENST00000477992(uc002vhf.3) ENST00000462034 ENST00000456575 ENST00000487321
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARPC2 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARPC2 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ARPC2 (NM_005731) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARPC2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARPC2 |
Additional cDNA sequence: AF006085.1 AF279893.1 AK290268.1 BC000590.2 BT006898.1 U50523.1 24/39 DOTS entries (see all 39): DT.97856683 DT.100801439 DT.91780855 DT.95260472 DT.100801444 DT.100801440 DT.103135 DT.100869812 DT.100869813 DT.120982542 DT.320157 DT.97760165 DT.95260449 DT.100039611 DT.120982521 DT.95318670 DT.100869814 DT.100869818 DT.120982493 DT.120982558 DT.320161 DT.91938977 DT.95284481 DT.97766961 24/865 AceView cDNA sequences (see all 865): BM974226 BG754749 W93590 BE741760 BU680054 AI636728 BU557387 BM875505 AW168393 AA430727 AL532406 AA600086 BM423660 BM019840 F26262 T32452 AA194487 AA722784 BQ426058 BQ676113 CA308191 BQ641499 BE386267 AW193778
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for ARPC2 (see all 12) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | · | 7c | · | 7d | · | 7e | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | · | 11c | ^ | 12 | ^ | 13 |
|---|
|
| SP1: | | | - | | - | | | | | | | | | | - | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | - | | | | |
| SP3: | | | | | | | | | | | | | | | - | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP5: | | | - | | - | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ARPC2
|
Expression
for ARPC2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARPC2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGGAGTTCA
About this image
See ARPC2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARPC2
SOURCE GeneReport for Unigene cluster: Hs.529303
SABiosciences Expression via Pathway-Focused PCR Array including ARPC2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARPC2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARPC2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARPC2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARPC2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARPC2 |
Orthologs
for ARPC2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for ARPC2 gene from 9/32 species (see all 32) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Arpc21 , 5 |
actin related protein 2/3 complex, subunit 21, 5 |
94.22(n)1
99.33(a)1 |
|
1 (38.49 cM)5
767091 NM_029711.11 NP_083987.11
742364975 |
chicken
(Gallus gallus) |
Aves |
ARPC21 |
actin related protein 2/3 complex, subunit 2, 34kDa |
85.56(n)
94.67(a) |
|
429041 XM_426598.3 XP_426598.2 |
lizard
(Anolis carolinensis) |
Reptilia |
ARPC26 |
-- |
90(a) |
1 ↔ 1 |
1(88909849-88940115) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.81282 |
Xenopus laevis, Similar to actin related protein 2/3 more |
79.59(n) |
|
BC041545.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.268572 |
Danio rerio cDNA clone MGC77769 IMAGE7001086, complete more |
79.59(n) |
|
BC064304.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Arc-p341 , 3 |
regulation of actin polymerization and/or
depolymerization more3
Arc-p341 |
75(a)3
67.12(n)1
75.76(a)1 |
|
38C63
353111 NM_136189.21 NP_610033.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
Y6D11A.23
arx-41 |
Protein ARX-41 |
70(a)3
67.89(n)1
70.9(a)1 |
|
III(862298-865250)3
1752471 NM_171077.41 NP_741088.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ARPC2A6arpc2b6 |
actin-related protein C2B |
24(a)21(a) |
many → 1many → 1 |
1(10960941-10963182) 2(14147503-14149799) |
rice
(Oryza sativa) |
Liliopsida |
---- |
ARPC2B, putative, expressed |
26(a)16(a) |
many → 1many → 1 |
1(26526432-26531523) 4(25422991-25425950) |
ENSEMBL Gene Tree for ARPC2 (if available)
TreeFam Gene Tree for ARPC2 (if available) |
Paralogs
for ARPC2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ARPC2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 2 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARPC2 (219081817 - 219119079 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARPC2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARPC2 |
|
Disorders
/ Diseases
for ARPC2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARPC2 for disorders About GeneDecksing
OMIM gene information: 604224
OMIM disorders: --
6  diseases for ARPC2: About MalaCardswiskott-aldrich syndrome diffuse scleroderma ulcerative colitis shigellosis
scleroderma gastric cancer
Human Genome Epidemiology (HuGE) Navigator: ARPC2 (2 documents)
Export disorders for ARPC2 gene to outside databases
|
Publications
for ARPC2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARPC2 gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with ARPC2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. (PubMed id 9230079)1, 2, 3 Welch M.D.... Mitchison T.J. (1997)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
- Reconstitution of human Arp2/3 complex reveals critical roles of individual subunits in complex structure and activity. (PubMed id 11741539)1, 2 Gournier H.... Welch M.D. (2001)
- Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins. (PubMed id 9359840)1, 3 Machesky L.M.... Segal A.W. (1997)
- Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13. (PubMed id 8812419)1, 2 Couch F.J.... Simard J. (1996)
- Insertions within the actin core of actin-related prot ein 3 (Arp3) modulate branching nucleation by Arp2/3 complex. (PubMed id 23148219)1 Liu S.L....Nolen B.J. (2013)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Rickettsia parkeri invasion of diverse host cells invo lves an Arp2/3 complex, WAVE complex and Rho-family GTPase-dependent pathway. (PubMed id 22188208)1 Reed S.C....Welch M.D. (2012)
- Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
|
External Searches for ARPC2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARPC2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARPC2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ARPC2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ARPC2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ARPC2 gene:
Search GeneIP for patents involving ARPC2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ARPC2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | OriGene Antibodies for ARPC2 | | OriGene shRNA RFP for ARPC2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARPC2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARPC2 | | | OriGene Protein Over-expression Lysate for ARPC2 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ARPC2 | | OriGene 3'-UTR Clone for ARPC2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARPC2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARPC2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ARPC2 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ARPC2 | | OriGene Custom Protein Services for ARPC2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARPC2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARPC2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARPC2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARPC2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARPC2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARPC2 |
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| | | | Search Tocris compounds for ARPC2 |
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 | | | ARPC2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARPC2 |
|  |  |  | | | | ThermoFisher Antibody for ARPC2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARPC2 |
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