Aliases for ARPC2 Gene
External Ids for ARPC2 Gene
Previous GeneCards Identifiers for ARPC2 Gene
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
GeneCards Summary for ARPC2 Gene
ARPC2 (Actin Related Protein 2/3 Complex Subunit 2) is a Protein Coding gene. Among its related pathways are Immune response CCR3 signaling in eosinophils and Regulation of actin dynamics for phagocytic cup formation. GO annotations related to this gene include actin filament binding and kinesin binding.
UniProtKB/Swiss-Prot for ARPC2 Gene
Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament.