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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARPC1A Gene

protein-coding   GIFtS: 59
GCID: GC07P098923

actin related protein 2/3 complex, subunit 1A, 41kDa

(Previous names: actin related protein 2/3 complex, subunit 1A (41 kD) )
 Explore 8 diseases affiliated with
ARPC1A via our new
 Human Malady Compendium 
Biological research products
for ARPC1A
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Actin Related Protein 2/3 Complex, Subunit 1A, 41kDa1 2     SOP2-Like Protein2 3
SOP2L1 2 3 5     Actin Related Protein 2/3 Complex, Subunit 1A (41 KD)1
Arc401 2     Actin Binding Protein (Schizosaccharomyces Pombe Sop2-Like)2
SOP2Hs1 2     Actin-Related Protein 2/3 Complex Subunit 1A2

External Ids:    HGNC: 7031   Entrez Gene: 105522   Ensembl: ENSG000002416857   OMIM: 6042205   UniProtKB: Q927473   

Export aliases for ARPC1A gene to outside databases

Previous GC identifers: GC07P097458 GC07P098521 GC07P098534 GC07P098568 GC07P098761 GC07P093559


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARPC1A:
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2
family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two
proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in
the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and
maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the
complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different
isoforms have been found for this gene. (provided by RefSeq, Jul 2010)

UniProtKB/Swiss-Prot: ARC1A_HUMAN, Q92747
Function: Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization
and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

Gene Wiki entry for ARPC1A


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007933.15  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARPC1A gene promoter:
         AhR   SREBP-1c   Arnt   SREBP-1b   AREB6   POU2F1   SREBP-1a   POU2F1a   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ARPC1A promoter sequence
   Search SABiosciences Chromatin IP Primers for ARPC1A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARPC1A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q

ARPC1A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARPC1A gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P098923:  view genomic region     (about GC identifiers)

Start:
98,923,496 bp from pter      End:
98,985,787 bp from pter
Size:
62,292 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 98,283,446-98,323,834     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ARC1A_HUMAN, Q92747 (See protein sequence)
Recommended Name: Actin-related protein 2/3 complex subunit 1A  
Size: 370 amino acids; 41569 Da
Subunit: Probable component of the Arp2/3 complex in which it may replace ARPC1B
Subcellular location: Cytoplasm, cytoskeleton (Probable)
Secondary accessions: A4D276 D6W5S1 Q7Z5U8 Q86WU5 Q8IXQ0

Explore the universe of human proteins at neXtProt for ARPC1A: NX_Q92747

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q92747

  • ARPC1A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001177925.1  NP_006400.2  

    ENSEMBL proteins: 
     ENSP00000412879   ENSP00000262942   ENSP00000408711   ENSP00000408578  
    Reactome Protein details: Q92747
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    Uscn Proteins for ARPC1A

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton ----
    GO:0015629actin cytoskeleton TAS8978670


    ARPC1A for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ARPC1A for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR017383 ARPC2/3_su1
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q92747

    ProtoNet protein and cluster: Q92747

    1 Blocks protein family: IPB001680 G-protein beta WD-40 repeat signature

    UniProtKB/Swiss-Prot: ARC1A_HUMAN, Q92747
    Similarity: Belongs to the WD repeat ARPC1 family
    Similarity: Contains 6 WD repeats


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ARC1A_HUMAN, Q92747
    Function: Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization
    and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks

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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--


    ARPC1A for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for ARPC1A:
     Decreased Tat-dependent transc  Increased peripheral focal adh 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/14 super-pathways (see all 14About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell adhesion_Integrin-mediated cell adhesion and migration
    Cell adhesion_Integrin-mediated cell adhesion and migration1.00
    Cytoskeleton remodeling_Integrin outside-in signaling0.37
    Cell adhesion Integrin-mediated cell adhesion and migration1.00
    Cytoskeleton remodeling Integrin outside-in signaling0.37
    Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases0.49
    Cytoskeleton remodeling Fibronectin-binding integrins in cell motility0.32
    Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases0.49
    Cytoskeleton remodeling_Fibronectin-binding integrins in cell motility0.32
    2G-protein signaling_RAC1 in cellular process
    G-protein signaling_RAC1 in cellular process1.00
    Cytoskeleton remodeling_CDC42 in cellular processes0.37
    G-protein signaling RAC1 in cellular process1.00
    Cytoskeleton remodeling CDC42 in cellular processes0.37
    3Regulation of actin dynamics for phagocytic cup formation
    Regulation of actin dynamics for phagocytic cup formation1.00
    Fcgamma receptor (FCGR) dependent phagocytosis0.80
    Role of myosins in phagosome formation0.80
    Branching and elongation of mother and daughter filaments0.29
    4Cytoskeleton remodeling Slit-Robo signaling
    Cytoskeleton remodeling Slit-Robo signaling1.00
    Cell adhesion_Cadherin-mediated cell adhesion0.28
    Development_Slit-Robo signaling0.92
    Cell adhesion Cadherin-mediated cell adhesion0.28
    5Immune response CD16 signaling in NK cells
    Immune response CD16 signaling in NK cells1.00
    Immune response_Role of DAP12 receptors in NK cells0.32
    Immune response_CD16 signaling in NK cells0.99
    Immune response Role of DAP12 receptors in NK cells0.32

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/13 EMD Millipore Pathways for ARPC1A (see all 13)
        Cytoskeleton remodeling Integrin outside-in signaling
    Immune response CD16 signaling in NK cells
    Cytoskeleton remodeling CDC42 in cellular processes
    Cytoskeleton remodeling Fibronectin-binding integrins in cell motility
    Immune response Role of DAP12 receptors in NK cells


    5/14 GeneGo (Thomson Reuters) Pathways for ARPC1A (see all 14)
        Cytoskeleton remodeling CDC42 in cellular processes
    Immune response CD16 signaling in NK cells
    Cytoskeleton remodeling Fibronectin-binding integrins in cell motility
    Neurophysiological process Receptor-mediated axon growth repulsion
    Cytoskeleton remodeling Integrin outside-in signaling

    1 BioSystems Pathway for ARPC1A 
        Pathogenic Escherichia coli infection

    5/6        Reactome Pathways for ARPC1A (see all 6)
        Role of myosins in phagosome formation
    Branching and elongation of mother and daughter filaments
    Regulation of actin dynamics for phagocytic cup formation
    Fcgamma receptor (FCGR) dependent phagocytosis
    Immune System


    5         Kegg Pathways  (Kegg details for ARPC1A):
        Fc gamma R-mediated phagocytosis
    Regulation of actin cytoskeleton
    Bacterial invasion of epithelial cells
    Pathogenic Escherichia coli infection
    Shigellosis


    ARPC1A for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARPC1A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/79 Interacting proteins for ARPC1A (Q927473 ENSP000002629424) via UniProtKB, MINT, STRING, and/or I2D (see all 79)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTR2P611603, ENSP000003672204I2D: score=7 STRING: ENSP00000367220
    ACTR3BQ9P1U13, ENSP000002560014I2D: score=7 STRING: ENSP00000256001
    AARSD1Q9BTE63I2D: score=3 
    MYO1EQ129653, ENSP000002882354I2D: score=3 STRING: ENSP00000288235
    PTGES3L-AARSD1Q9BTE63I2D: score=3 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030036actin cytoskeleton organization TAS8978670
    GO:0030833regulation of actin filament polymerization IEA--


    ARPC1A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ARPC1A
    Search CenterWatch for drugs/clinical trials and news about ARPC1A / ARC1A 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARPC1A gene (2 alternative transcripts): 
    NM_001190996.1  NM_006409.3  

    Unigene Cluster for ARPC1A:

    Actin related protein 2/3 complex, subunit 1A, 41kDa
    Hs.124126  [show with all ESTs]
    Unigene Representative Sequence: NM_001190996
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000441989 ENST00000262942(uc003upx.2 uc003upy.2) ENST00000432786
    ENST00000471960 ENST00000463009 ENST00000477240 ENST00000432884(uc011kit.2)


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    Additional cDNA sequence: 

    AB209059.1 AK223015.1 BC006445.1 BC039594.1 BC047889.1 BC054027.1 Y08999.1 

    24/25 DOTS entries (see all 25):

    DT.118915  DT.100854337  DT.100854311  DT.100854339  DT.100854340  DT.99940694  DT.92454422  DT.95278412 
    DT.121054645  DT.121054663  DT.100854326  DT.101970044  DT.121054582  DT.121461824  DT.100768114  DT.100854333 
    DT.121054644  DT.121054662  DT.121462228  DT.92018573  DT.92064363  DT.92454421  DT.95278418  DT.95300095 

    24/653 AceView cDNA sequences (see all 653):

    BM459660 BQ882930 CN483140 BC006445 CR615755 CB215115 BF727013 CR606734 
    BX384634 CR611053 BU682205 BG574518 BU176510 AA554309 AA746084 BU616553 
    CR618987 CR591610 AA019185 BM856008 BM978069 BE875688 BQ670736 CB215253 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARPC1A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACAAACTGTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ARPC1A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARPC1A

    SOURCE GeneReport for Unigene cluster: Hs.124126
        SABiosciences Custom PCR Arrays for ARPC1A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARPC1A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ARPC1A gene from 9/35 species (see all 35)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves ARPC1A1 actin related protein 2/3 complex, subunit 1A, 41kDa 83.69(n)
    95.95(a)
      770269  NM_001079495.1  NP_001072963.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARPC1A6
    --
    95(a)
    1 ↔ 1
    GL343725.1(189313-197137)
    African clawed frog
    (Xenopus laevis)
    Amphibia arpc1a-prov2 actin related protein 2/3 complex, subunit 1A, 41kDa 78.97(n)    BC041267.1 
    zebrafish
    (Danio rerio)
    Actinopterygii arpc1a2 actin related protein 2/3 complex, subunit 1A 79.22(n)   394243  AY398313.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Sop21 , 3 actin filament-based process actin binding3
    Suppressor of profilin 21
    58(a)3
    59.6(n)1
    59.31(a)1
      34D63
    347931  NM_057248.41  NP_476596.11 
    worm
    (Caenorhabditis elegans)
    Secernentea arx-31 Protein ARX-3 58.12(n)
    57.75(a)
      3565442  NM_067169.3  NP_499570.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ARC40(YBR234C)4
    ARC401
    Subunit of the ARP2/3 complex, which is required for more4
    Arc40p1
    45.73(n)1
    40.63(a)1
      2(686592-685438)4
    8525361, 4  NP_009793.11, 4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ARPC16
    ARPC16
    actin-related protein C1A
    41(a)
    40(a)
    many ↔ many
    many ↔ many
    2(13346122-13349980)
    2(13152789-13157107)
    rice
    (Oryza sativa)
    Liliopsida --
    WD domain, G-beta repeat domain containing protein...
    39(a)
    1 → many
    2(35051061-35056660)


    ENSEMBL Gene Tree for ARPC1A (if available)
    TreeFam Gene Tree for ARPC1A (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARPC1A gene
    ARPC1B2  
    1 SIMAP similar gene for ARPC1A using alignment to 5 protein entries:     ARC1A_HUMAN (see all proteins):
    ARPC1B

    ARPC1A for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for ARPC1A
    PGOHUM00000234760 PGOHUM00000240511 PGOHUM00000238151 PGOHUM00000245618 PGOHUM00000235652


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/667 NCBI SNPs in ARPC1A are shown (see all 667    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs69534761,2
    C,F,A,H,--98921600(+) TGGCAG/CCAGTG 2 -- us2k110Minor allele frequency- C:0.49NA WA CSA EA 370
    rs1474470831,2
    --98921696(+) TTAGAG/TTCTCA 2 -- us2k10--------
    rs570255111,2
    C,--98921779(+) GCCCCC/TACTGA 2 -- us2k12Minor allele frequency- T:0.11WA 120
    rs1400247521,2
    --98921948(+) CTGCAC/GTAACT 2 -- us2k10--------
    rs102744071,2
    C,A,H,--98922090(+) CGTCTG/ATACTA 2 -- us2k12Minor allele frequency- A:0.00CSA 2
    rs1932941901,2
    --98922139(+) GTAGTC/TCCAGC 2 -- us2k10--------
    rs125394801,2
    C,H,--98922222(+) actgcG/Actcca 2 -- us2k11Minor allele frequency- A:0.50WA 2
    rs1842641481,2
    --98922243(+) CAGAGA/CAAGGC 2 -- us2k10--------
    rs1895744561,2
    --98922317(+) CTCACC/GTTACA 2 -- us2k10--------
    rs1809449731,2
    --98922368(+) TGGCGC/TTGGGC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARPC1A (98923496 - 98985787 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for ARPC1A
         2 CNVs: 4547 4548

    SABiosciences Cancer Mutation PCR Assays
    1 SABiosciences qBiomarker Copy Number PCR Array containing ARPC1A:
    Pancreatic Cancer
    Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARPC1A
    DNA2.0 Custom Variant and Variant Library Synthesis for ARPC1A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ARPC1A for disorders           About GeneDecksing

    OMIM gene information: 604220    OMIM disorders: --

    8 diseases for ARPC1A:    About MalaCards
    lattice corneal dystrophy    boomerang dysplasia    corneal dystrophy    shigellosis
    crohn's disease    pancreatic cancer    pancreatitis    malaria

    Human Genome Epidemiology (HuGE) Navigator: ARPC1A (3 documents)

    Export disorders for ARPC1A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARPC1A gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with ARPC1A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Fission yeast Sop2p: a novel and evolutionarily conserved protein that interacts with Arp3p and modulates profilin function. (PubMed id 8978670)1, 2, 3 Balasubramanian M.K.... Gould K.L. (1996)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    4. The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. (PubMed id 9230079)1, 3 Welch M.D.... Mitchison T.J. (1997)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Eight common genetic variants associated with serum D HEAS levels suggest a key role in ageing mechanisms. (PubMed id 21533175)1 Zhai G....Wallaschofski H. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10552 HGNC: 703 AceView: ARPC1A Ensembl:ENSG00000241685 euGenes: HUgn10552
    ECgene: ARPC1A Kegg: 10552 H-InvDB: ARPC1A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARPC1A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARPC1A gene:
    Search GeneIP for patents involving ARPC1A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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