Aliases for ARNT Gene
Aliases for ARNT Gene
External Ids for ARNT Gene
- HGNC: 700
- Entrez Gene: 405
- Ensembl: ENSG00000143437
- OMIM: 126110
- UniProtKB: P27540
Previous GeneCards Identifiers for ARNT Gene
- GC01M148624
- GC01M146529
- GC01M147557
- GC01M147998
- GC01M147595
- GC01M149048
- GC01M122159
Summaries for ARNT Gene
-
This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013]
GeneCards Summary for ARNT Gene
ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator) is a Protein Coding gene. Diseases associated with ARNT include Hypoxia and Renal Cell Carcinoma. Among its related pathways are Cytochrome P450 - arranged by substrate type and Diuretics Pathway, Pharmacodynamics. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein heterodimerization activity. An important paralog of this gene is ARNT2.
UniProtKB/Swiss-Prot for ARNT Gene
-
Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARNT Gene
Genomics for ARNT Gene
Regulatory Elements for ARNT Gene
Enhancers for ARNT Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around ARNT on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the ARNT gene promoter:
Regulatory Element Products
Genomic Location for ARNT Gene
- Chromosome:
- 1
- Start:
- 150,809,705 bp from pter
- End:
- 150,876,768 bp from pter
- Size:
- 67,064 bases
- Orientation:
- Minus strand
Genomic View for ARNT Gene
Genes around ARNT on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1q21.3 by Ensembl
- 1q21.3 by Entrez Gene
- 1q21.3 by HGNC
ARNT Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for ARNT Gene
Proteins for ARNT Gene
-
Protein details for ARNT Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P27540-ARNT_HUMAN
- Recommended name:
- Aryl hydrocarbon receptor nuclear translocator
- Protein Accession:
- P27540
- B2R9H1
- C4AMA1
- F8WAP6
- Q59ED4
- Q5QP39
- Q8NDC7
Protein attributes for ARNT Gene
- Size:
- 789 amino acids
- Molecular mass:
- 86636 Da
- Quaternary structure:
-
- Efficient DNA binding requires dimerization with another bHLH protein. Forms a heterodimer with AHR, AHRR, HIF1A and EPAS1/HIF2A as well as with other bHLH proteins. Interacts with TACC3 (By similarity). Interacts with NOCA7. Heterodimer with HIF1A.
- SequenceCaution:
-
- Sequence=BAD93114.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAD38953.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};
Three dimensional structures from OCA and Proteopedia for ARNT Gene
Protein Expression for ARNT Gene
Post-translational modifications for ARNT Gene
Other Protein References for ARNT Gene
- ENSEMBL proteins:
- REFSEQ proteins:
-
- NP_001184254.1
- NP_001272964.1
- NP_001272965.1
- NP_001337153.1
- NP_001337154.1
- NP_001337155.1
- NP_001659.1
- NP_848514.1
- XP_005245208.1
- XP_005245210.1
- XP_005245211.1
- XP_005245214.1
- XP_011507844.1
- XP_011507845.1
- XP_011507846.1
- XP_011507847.1
- XP_011507848.1
- XP_011507849.1
- XP_016856777.1
- XP_016856778.1
- XP_016856779.1
- XP_016856780.1
- XP_016856781.1
- XP_016856782.1
- XP_016856783.1
- XP_016856784.1
- XP_016856785.1
Antibody Products
- R&D Systems Antibodies for ARNT (ARNT/HIF-1 beta)
- Cell Signaling Technology (CST) Antibodies for ARNT (ARNT)
-
Custom Antibody ServicesOriGene Antibodies for ARNT
- AM31721PU-N
- AP07898PU-N
- TA301442
- TA301443
- TA311902
- TA324092
- TA324545
- TA326733
- TA326734
- TA501147
- CF501147
- TA501148
- CF501148
- TA501149
- CF501149
- TA501150
- CF501150
- TA501249
- CF501249
- TA590094
- TA600042
- TA700042
- TA700046
- TA501147S
- TA501149AM
- TA501149BM
- TA501149CM
- TA501149DM
- TA501149EM
- TA501149FM
- TA501149GM
- TA501149HM
- TA501149JM
- TA501150AM
- TA501150BM
- TA501150CM
- TA501150DM
- TA501150EM
- TA501150FM
- TA501150GM
- TA501150HM
- TA501150JM
- Novus Biologicals Antibodies for ARNT
-
Cloud-Clone Corp. Antibodies for ARNT
- Invitrogen Antibodies for ARNT
- antibodies-online Antibodies for ARNT: See all 150
- GeneTex ARNT antibody for ARNT
-
Santa Cruz Biotechnology (SCBT) Antibodies for ARNT
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for ARNT
- Origene Custom Protein Services for ARNT
-
Cloud-Clone Corp. Proteins for ARNT
- antibodies-online Proteins for ARNT: See all 10
- Search antibodies-online for peptides
- Search GeneTex for Proteins for ARNT
No data available for DME Specific Peptides for ARNT Gene
Domains & Families for ARNT Gene
Gene Families for ARNT Gene
Protein Domains for ARNT Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for ARNT Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for ARNT Gene
Function for ARNT Gene
Molecular function for ARNT Gene
- GENATLAS Biochemistry:
- aryl hydrocarbon receptor nuclear translocator,dioxin receptor translocator,constituvely expressed for activation of genes involved in metabolism,angiogenesis and apoptosis
- UniProtKB/Swiss-Prot Function:
- Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | -- |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | TAS | 1317062 |
| GO:0003705 | contributes_to transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | IDA | 7539918 |
| GO:0003713 | transcription coactivator activity | TAS,IEA | -- |
| GO:0004874 | aryl hydrocarbon receptor activity | IEA | -- |
Phenotypes for ARNT Gene
- MGI mutant phenotypes for ARNT:
-
inferred from 6 alleles
- mortality/aging
- cellular phenotype
- normal phenotype
- growth/size/body region phenotype
- immune system phenotype
- nervous system phenotype
- homeostasis/metabolism phenotype
- cardiovascular system phenotype
- neoplasm
- reproductive system phenotype
- endocrine/exocrine gland phenotype
- integument phenotype
- embryo phenotype
- hematopoietic system phenotype
- renal/urinary system phenotype
- liver/biliary system phenotype
- craniofacial phenotype
- GenomeRNAi human phenotypes for ARNT:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARNT
-
-
ViGene Biosciences lentiviral particle packaged cDNA for ARNT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARNT gene
- Search ViGene Biosciences for ARNT
CRISPR Products
-
OriGene CRISPR knockouts for ARNT
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARNT
- GenScript: Design CRISPR guide RNA sequences for ARNT
miRNA for ARNT Gene
- miRTarBase miRNAs that target ARNT
-
- hsa-mir-107 (MIRT004537)
- hsa-mir-877-3p (MIRT037117)
- hsa-mir-324-5p (MIRT043236)
- hsa-mir-4639-3p (MIRT111341)
- hsa-mir-221-3p (MIRT438219)
- hsa-mir-218-5p (MIRT441179)
- hsa-mir-6873-3p (MIRT610760)
- hsa-mir-3941 (MIRT610761)
- hsa-mir-933 (MIRT610762)
- hsa-mir-550b-3p (MIRT610763)
- hsa-mir-6817-3p (MIRT610764)
- hsa-mir-7110-3p (MIRT610765)
- hsa-mir-1304-3p (MIRT610766)
- hsa-mir-3680-5p (MIRT610767)
- hsa-mir-4798-3p (MIRT610768)
- hsa-mir-4789-3p (MIRT610769)
- hsa-mir-603 (MIRT610770)
- hsa-mir-362-3p (MIRT610771)
- hsa-mir-329-3p (MIRT610772)
- hsa-mir-8485 (MIRT610773)
- hsa-mir-4717-3p (MIRT628709)
Transcription Factor Targets for ARNT Gene
Targeted motifs for ARNT Gene
HOMER Transcription Factor Regulatory Elements motif ARNT
- Consensus sequence: TBGCACGCAA Submotif: canonical Cell Type: MCF7
miRNA Products
- Search ViGene Biosciences for ARNT
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ARNT
- Browse OriGene Inhibitory RNA Products For ARNT
-
ViGene Biosciences ready-to-package AAV shRNAs for ARNT gene
Clone Products
-
OriGene ORF clones in human for ARNT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ARNT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ARNT
- VectorBuilder custom plasmid, inducible vectors for ARNT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARNT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for ARNT
-
ViGene Biosciences adenoviral particle packaged cDNA for ARNT gene
-
ViGene Biosciences lentiviral particle packaged cDNA for ARNT gene
-
ViGene Biosciences ready-to-package AAV shRNAs for ARNT gene
No data available for Enzyme Numbers (IUBMB) and Human Phenotype Ontology for ARNT Gene
Localization for ARNT Gene
Subcellular locations from UniProtKB/Swiss-Prot for ARNT Gene
- Nucleus.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| mitochondrion | 1 |
| cytosol | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA,TAS | 8089148 |
| GO:0005654 | nucleoplasm | TAS | -- |
| GO:0005667 | transcription factor complex | IEA | -- |
| GO:0005737 | cytoplasm | IEA | -- |
| GO:0016604 | nuclear body | IDA | -- |
Pathways & Interactions for ARNT Gene
Pathways by source for ARNT Gene
1 GeneTex pathway for ARNT Gene
2 Cell Signaling Technology pathways for ARNT Gene
10 BioSystems pathways for ARNT Gene
15 Reactome pathways for ARNT Gene
1 PharmGKB pathway for ARNT Gene
4 KEGG pathways for ARNT Gene
3 GeneGo (Thomson Reuters) pathways for ARNT Gene
2 R&D Systems pathways for ARNT Gene
2 Qiagen pathways for ARNT Gene
Interacting Proteins for ARNT Gene
Selected Interacting proteins:
P27540-ARNT_HUMAN
ENSP00000351407
for ARNT Gene via
IID
STRING
MINT
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001666 | response to hypoxia | IDA | 8756616 |
| GO:0001892 | embryonic placenta development | IEA | -- |
| GO:0001938 | positive regulation of endothelial cell proliferation | IC | 8756616 |
| GO:0006351 | transcription, DNA-templated | TAS | 1317062 |
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
Transcripts for ARNT Gene
mRNA/cDNA for ARNT Gene
- (28) REFSEQ mRNAs :
- (12) Additional mRNA sequences :
- (688) Selected AceView cDNA sequences:
- (12) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for ARNT Gene
CRISPR Products
-
OriGene CRISPR knockouts for ARNT
-
Santa Cruz Biotechnology (SCBT) CRISPR for ARNT
- GenScript: Design CRISPR guide RNA sequences for ARNT
miRNA Products
- Search ViGene Biosciences for ARNT
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for ARNT
- Browse OriGene Inhibitory RNA Products For ARNT
-
ViGene Biosciences ready-to-package AAV shRNAs for ARNT gene
Clone Products
-
OriGene ORF clones in human for ARNT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for ARNT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ARNT
- VectorBuilder custom plasmid, inducible vectors for ARNT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARNT
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: |
| ExUns: | 18 | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | ^ | 22 | ^ | 23a | · | 23b | · | 23c | · | 23d |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||||
| SP2: | |||||||||||||||||||
| SP3: | |||||||||||||||||||
| SP4: | - | - | - | - | |||||||||||||||
| SP5: | |||||||||||||||||||
| SP6: | |||||||||||||||||||
| SP7: | |||||||||||||||||||
| SP8: |
Expression for ARNT Gene
This gene is overexpressed in Placenta (19.7), Heart (13.1), Ovary (9.6), and Blymphocyte (6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ARNT Gene
- Elite partner
NURSA nuclear receptor signaling pathways regulating expression of ARNT Gene:
ARNTSOURCE GeneReport for Unigene cluster for ARNT Gene:
Hs.632446Evidence on tissue expression from TISSUES for ARNT Gene
- Liver(4.6)
- Nervous system(4.6)
- Muscle(2.7)
- Heart(2.5)
- Lung(2.4)
- Kidney(2.3)
Primer Products
-
OriGene qPCR primer pairs for ARNT
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARNT Gene
Orthologs for ARNT Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | ARNT 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | ARNT 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | ARNT 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Arnt 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Arnt 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | ARNT 35 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | ARNT 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | ARNT 35 34 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | ARNT 35 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | arnt 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | arnt 35 |
|
OneToOne | |
| fruit fly (Drosophila melanogaster) |
Insecta | tgo 36 35 |
|
||
| worm (Caenorhabditis elegans) |
Secernentea | aha-1 36 35 |
|
||
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2012 35 |
|
OneToMany |
- Species where no ortholog for ARNT was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for ARNT Gene
Paralogs for ARNT Gene
(6) SIMAP similar genes for ARNT Gene using alignment to 9 proteins:
Variants for ARNT Gene
| SNP ID | Clin | Chr 01 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000042944 | -- | 150,828,800(+) | TATAC(G/T)GGTAT | intron-variant | |
| rs1000145063 | -- | 150,874,814(+) | AAAGC(C/T)GTTTC | intron-variant | |
| rs1000175450 | -- | 150,862,157(+) | TACTC(C/T)GTACT | intron-variant | |
| rs1000182714 | -- | 150,811,126(+) | TTTAG(G/T)TAATG | utr-variant-3-prime | |
| rs1000225673 | -- | 150,840,214(+) | TCAGC(A/C)TGGGT | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3353935 | CNV | insertion | 20981092 |
| esv5926 | CNV | gain | 19470904 |
| nsv1008496 | CNV | gain | 25217958 |
| nsv1010875 | CNV | gain | 25217958 |
| nsv1122405 | CNV | deletion | 24896259 |
| nsv2788 | CNV | deletion | 18451855 |
| nsv2810 | CNV | deletion | 18451855 |
| nsv437169 | CNV | loss | 16327808 |
Residual Variation Intolerance Score:
6.64% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.16;
39.21% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for ARNT Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- ARNT
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARNT Gene
Disorders for ARNT Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hypoxia |
|
|
| renal cell carcinoma |
|
|
Search ARNT in MalaCards
View complete list of genes associated with diseases
Relevant External Links for ARNT
No data available for UniProtKB/Swiss-Prot and Genatlas for ARNT Gene
Publications for ARNT Gene
- Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis. (PMID: 18366646) Das S.K. … Elbein S.C. (BMC Med. Genet. 2008) 3 22 46 64
- The aryl hydrocarbon receptor nuclear translocator gene polymorphism in patients with recurrent miscarriage. (PMID: 16364012) Sullivan A.E. … Silver R.M. (Am. J. Reprod. Immunol. 2006) 3 22 46 64
- Analysis of the AhR, ARNT, and AhRR gene polymorphisms: genetic contribution to endometriosis susceptibility and severity. (PMID: 16084889) Tsuchiya M. … Ikenoue T. (Fertil. Steril. 2005) 3 22 46 64
- Human arylhydrocarbon receptor repressor (AHRR) gene: genomic structure and analysis of polymorphism in endometriosis. (PMID: 11393538) Watanabe T. … Inazawa J. (J. Hum. Genet. 2001) 3 22 46 64
- Functional characterization of DNA-binding domains of the subunits of the heterodimeric aryl hydrocarbon receptor complex imputing novel and canonical basic helix-loop-helix protein-DNA interactions. (PMID: 8621524) Bacsi S.G. … Hankinson O. (J. Biol. Chem. 1996) 3 4 22 64
Products for ARNT Gene
- R&D Systems Antibodies for ARNT (ARNT/HIF-1 beta)
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for ARNT
- AM31721PU-N
- AP07898PU-N
- TA301442
- TA301443
- TA311902
- TA324092
- TA324545
- TA326733
- TA326734
- TA501147
- CF501147
- TA501148
- CF501148
- TA501149
- CF501149
- TA501150
- CF501150
- TA501249
- CF501249
- TA590094
- TA600042
- TA700042
- TA700046
- TA501147S
- TA501149AM
- TA501149BM
- TA501149CM
- TA501149DM
- TA501149EM
- TA501149FM
- TA501149GM
- TA501149HM
- TA501149JM
- TA501150AM
- TA501150BM
- TA501150CM
- TA501150DM
- TA501150EM
- TA501150FM
- TA501150GM
- TA501150HM
- TA501150JM
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for ARNT
- Origene Custom Protein Services for ARNT
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for ARNT
- Browse OriGene Inhibitory RNA Products For ARNT
- OriGene qPCR primer pairs for ARNT
- OriGene CRISPR knockouts for ARNT
- OriGene ORF clones in human for ARNT
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For ARNT
- GenScript: Next-day shipping cDNA ORF clone for ARNT in any vector
- GenScript Custom Purified and Recombinant Proteins Services for ARNT
- GenScript Custom Assay Services for ARNT
- GenScript Custom overexpressing Cell Line Services for ARNT
- GenScript: Design CRISPR guide RNA sequences for ARNT
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for ARNT
- Cell Signaling Technology (CST) Antibodies for ARNT (ARNT)
- Search for Antibodies & Assays
- Sino Biological Human cDNA Clone for ARNT
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for ARNT
- Novus Biologicals proteins and lysates for ARNT
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for ARNT
- Cloud-Clone Corp. Proteins for ARNT
- Cloud-Clone Corp Assay Kits for ARNT
- Invitrogen Antibodies for ARNT
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for ARNT
- antibodies-online Antibodies for ARNT: See all 150
- antibodies-online Kits for ARNT: See all 16
- antibodies-online Proteins for ARNT: See all 10
- Search antibodies-online for peptides
- GeneTex ARNT antibody for ARNT
- Search GeneTex for Proteins for ARNT
- ViGene Biosciences adenoviral particle packaged cDNA for ARNT gene
- ViGene Biosciences lentiviral particle packaged cDNA for ARNT gene
- ViGene Biosciences ready-to-package AAV shRNAs for ARNT gene
- Search ViGene Biosciences for ARNT
- Santa Cruz Biotechnology (SCBT) Antibodies for ARNT
- Search Santa Cruz Biotechnology (SCBT) for ARNT siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for ARNT
- Horizon Cell Lines for ARNT
- Cyagen custom Knockout/knockin (KOKI) mouse models for ARNT
- VectorBuilder custom plasmid, inducible vectors for ARNT
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for ARNT
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for ARNT Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer