Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ARMS2 Gene

protein-coding   GIFtS: 40
GCID: GC10P124205

Age-Related Maculopathy Susceptibility 2

  See ARMS2-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Age-Related Maculopathy Susceptibility 21 2
ARMD82 5
Age-Related Maculopathy Susceptibility Protein 22
LOC3877155

External Ids:    HGNC: 326851   Entrez Gene: 3877152   Ensembl: ENSG000002546367   OMIM: 6113135   UniProtKB: P0C7Q23   

Export aliases for ARMS2 gene to outside databases

Previous GC identifer: GC10P117844


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ARMS2 Gene:
This gene encodes a protein that is thought to play a role in diseases in the elderly. Mutations in this gene have
been associated with age-related macular degeneration. (provided by RefSeq, Oct 2008)

GeneCards Summary for ARMS2 Gene:
ARMS2 (age-related maculopathy susceptibility 2) is a protein-coding gene. Diseases associated with ARMS2 include choroiditis, and age-related macular degeneration 8.

Gene Wiki entry for ARMS2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NC_018921.2  NT_030059.14  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARMS2 gene promoter:
         NF-1   NF-1/L   Pax-5   E47   CREB   MEF-2A   N-Myc   deltaCREB   aMEF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for ARMS2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARMS2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.13   Ensembl cytogenetic band:  10q26.13   HGNC cytogenetic band: 10q26.13

ARMS2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARMS2 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P124205:  view genomic region     (about GC identifiers)

Start:
124,214,169 bp from pter      End:
124,216,868 bp from pter
Size:
2,700 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ARMS2_HUMAN, P0C7Q2 (See protein sequence)
Recommended Name: Age-related maculopathy susceptibility protein 2  
Size: 107 amino acids; 11437 Da
Secondary accessions: B2Y7I5

Explore the universe of human proteins at neXtProt for ARMS2: NX_P0C7Q2

Explore proteomics data for ARMS2 at MOPED


See ARMS2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_001093137.1  
ENSEMBL proteins: 
 ENSP00000436682  

ARMS2 Human Recombinant Protein Products:

Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
OriGene Purified Protein for ARMS2
OriGene Protein Over-expression Lysate for ARMS2
OriGene MassSpec for ARMS2
OriGene Custom Protein Services for ARMS2
GenScript Custom Purified and Recombinant Proteins Services for ARMS2
Novus Biologicals ARMS2 Protein
Novus Biologicals ARMS2 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for ARMS2

 
Search eBioscience for Proteins for ARMS2 

ARMS2 Antibody Products:

EMD Millipore Mono- and Polyclonal Antibodies for the study of ARMS2
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for ARMS2
Novus Biologicals ARMS2 Antibody
Abcam antibodies for ARMS2
Cloud-Clone Corp. Antibodies for ARMS2
Search ThermoFisher Antibodies for ARMS2
LSBio Antibodies in human, mouse, rat for ARMS2

ARMS2 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for ARMS2
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for ARMS2
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for ARMS2
Cloud-Clone Corp. CLIAs for ARMS2
Search eBioscience for ELISAs for ARMS2 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TryGeneCards Plus

ProtoNet protein and cluster: P0C7Q2


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARMS2
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ARMS2

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARMS2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARMS2

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat ARMS2 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate ARMS2
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for ARMS2
Predesigned siRNA for gene silencing in human, mouse, rat ARMS2

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for ARMS2

Clone
Products:
     
OriGene clones in human, mouse for ARMS2 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ARMS2 (NM_001099667)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMS2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMS2

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for ARMS2
Browse ESI BIO Cell Lines and PureStem Progenitors for ARMS2 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMS2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
About This Section

TryGeneCards Plus

Subcellular locations from UniProtKB/Swiss-Prot
ARMS2_HUMAN, P0C7Q2: Cytoplasm

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001917photoreceptor inner segment IDA18511946
GO:0005739mitochondrion IDA18511946

Find genes that share ontologies with ARMS2           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
About This Section

TryGeneCards Plus



    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARMS2
Interactions:

    GeneGlobe Interaction Network for ARMS2

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001895retina homeostasis IMP18511946

Find genes that share ontologies with ARMS2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
About This Section

TryGeneCards Plus
Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for ARMS2



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
About This Section

TryGeneCards Plus

REFSEQ mRNAs for ARMS2 gene: 
NM_001099667.1  

Unigene Cluster for ARMS2:

Age-related maculopathy susceptibility 2
Hs.120359  [show with all ESTs]
Unigene Representative Sequence: CB998303
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000528446(uc001lgi.3)
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat ARMS2 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate ARMS2
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for ARMS2
Predesigned siRNA for gene silencing in human, mouse, rat ARMS2
Clone
Products:
     
OriGene clones in human, mouse for ARMS2 (see all 4)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: ARMS2 (NM_001099667)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMS2
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMS2
Primer
Products:
    
OriGene qPCR primer pairs and template standards for ARMS2
OriGene qSTAR qPCR primer pairs in human, mouse for ARMS2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARMS2
  QuantiTect SYBR Green Assays in human, mouse, rat ARMS2
  QuantiFast Probe-based Assays in human, mouse, rat ARMS2

Additional mRNA sequence: 

BC066349.1 BC090924.1 

1 DOTS entry:

DT.422618 

19 AceView cDNA sequences:

CB997927 CB993395 AI167912 CB997971 BC066349 BG201701 BG206949 CB998303 
BU751733 BG210064 BG185707 BG182059 BG201192 BG204293 R23880 BG216326 
BG195069 H00398 BG194076 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TryGeneCards Plus

ARMS2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATCCCAGCTG
ARMS2 Expression
About this image

ARMS2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

ARMS2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.120359

UniProtKB/Swiss-Prot: ARMS2_HUMAN, P0C7Q2
Tissue specificity: Detected in retina and placenta

    Custom PCR Arrays for ARMS2
Primer
Products:
OriGene qPCR primer pairs and template standards for ARMS2
OriGene qSTAR qPCR primer pairs in human, mouse for ARMS2
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARMS2
QuantiTect SYBR Green Assays in human, mouse, rat ARMS2
QuantiFast Probe-based Assays in human, mouse, rat ARMS2
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMS2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

TryGeneCards Plus

This gene was present in the common ancestor of human and chimp.

Orthologs for ARMS2 gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
chimpanzee
(Pan troglodytes)
Mammalia ARMS21 age-related maculopathy susceptibility 2 99.37(n)
98.11(a)
  450791  XM_529353.3  XP_529353.1 


ENSEMBL Gene Tree for ARMS2 (if available)
TreeFam Gene Tree for ARMS2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section

TryGeneCards Plus
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
About This Section

TryGeneCards Plus

Selected SNPs for ARMS2 (see all 157)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 10 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs104909241,2,,4
C,F,Hother1124573377(+) CAGCTG/TCTAAA 2 A S mis129Minor allele frequency- T:0.30NS EA NA CSA WA 2872
rs615449451,2
C--124214601(+) TGGTG-/GT/TG 
        
CCCTG
1 -- int10--------
rs1112704481,2
C--124216170(+) ATCTC-/AAAAAA 1 -- int11Minor allele frequency- A:0.50CSA 2
rs79123431,2
H--124216375(+) ATATCG/ATCATG 1 -- int14Minor allele frequency- A:0.00NS EA 418
rs725116531,2
C--124216384(+) GTGTC-/AT/TA 
        
TTTAA
1 -- int10--------
rs752029181,2
C--124216384(+) TGTGTA/CTTTAA 1 -- int10--------
rs106643161,2
C--124216385(+) TGTCT-/A/    
   AT
/TA
TTAAA
1 -- int10--------
rs3723359951,2
C--124216391(+) TTAAAA/GATGCA 1 -- int10--------
rs362130741,2
C--124216397(+) ATGCAT/CATTAC 1 -- int13Minor allele frequency- C:0.09NA WA 240
rs70881281,2
C--124216410(+) AATCTA/GTTTTT 1 -- int13Minor allele frequency- G:0.10CSA WA NA 239

HapMap Linkage Disequilibrium report for ARMS2 (124214169 - 124216868 bp)

Structural Variations
     Database of Genomic Variants (DGV) 7 variations for ARMS2:    About this table    
Variant IDTypeSubtypePubMed ID
esv2742095CNV Deletion23290073
esv2663177CNV Deletion23128226
esv2742106CNV Deletion23290073
esv28769CNV Loss19812545
esv9290CNV Loss19470904
nsv7580CNV Loss18451855
nsv825594CNV Gain20364138

Human Gene Mutation Database (HGMD): ARMS2
Site Specific Mutation Identification with PCR Assays
Search QIAGEN SeqTarget long-range PCR primers for resequencing ARMS2
DNA2.0 Custom Variant and Variant Library Synthesis for ARMS2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TryGeneCards Plus
OMIM gene information: 611313   
OMIM disorders: 613778  
UniProtKB/Swiss-Prot: ARMS2_HUMAN, P0C7Q2
  • Macular degeneration, age-related, 8 (ARMD8) [MIM:613778]: A form of age-related macular degeneration, a
    multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most
    patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid
    that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch
    membrane. Note=Disease susceptibility is associated with variations affecting the gene represented in this entry

  • 6 diseases for ARMS2:    
    About MalaCards
    choroiditis    age-related macular degeneration 8    multifocal choroiditis    retinal drusen
    retinal disease    age related macular degeneration


    Find genes that share disorders with ARMS2           About GenesLikeMe

    Genetic Association Database (GAD): ARMS2
    Human Genome Epidemiology (HuGE) Navigator: ARMS2 (86 documents)

    Export disorders for ARMS2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ARMS2 gene, integrated from 10 sources (see all 160):
    (articles sorted by number of sources associating them with ARMS2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Hypothetical LOC387715 is a second major susceptibility gene for age- related macular degeneration, contributing independently of complement factor H to disease risk. (PubMed id 16174643)1, 2, 3, 4 Rivera A.... Weber B.H.F. (Hum. Mol. Genet. 2005)
    2. Localization of age-related macular degeneration-associated ARMS2 in cytosol, not mitochondria. (PubMed id 19255159)1, 2, 4 Wang G.... Pericak-Vance M.A. (Invest. Ophthalmol. Vis. Sci. 2009)
    3. Variants in the 10q26 gene cluster (LOC387715 and HTRA1) exhibit enhanced risk of age-related macular degeneration along with CFH in Indian patients. (PubMed id 18436811)1, 2, 4 Kaur I.... Chakrabarti S. (Invest. Ophthalmol. Vis. Sci. 2008)
    4. CFH and LOC387715/ARMS2 genotypes and treatment with antioxidants and zinc for age-related macular degeneration. (PubMed id 18423869)1, 2, 4 Klein M.L.... Seddon J.M. (Ophthalmology 2008)
    5. A variant of mitochondrial protein LOC387715/ARMS2, not HTRA1, is strongly associated with age-related macular degeneration. (PubMed id 17884985)1, 2, 4 Kanda A.... Swaroop A. (Proc. Natl. Acad. Sci. U.S.A. 2007)
    6. Susceptibility genes for age-related maculopathy on chromosome 10q26. (PubMed id 16080115)1, 3, 4 Jakobsdottir J....Gorin M.B. (Am. J. Hum. Genet. 2005)
    7. Simultaneous mutation detection in 90 retinal disease genes in multiple patients using a custom-designed 300-kb retinal resequencing chip. (PubMed id 20801516)1, 4 Booij J.C....Florijn R.J. (Ophthalmology 2011)
    8. ARMS2/HTRA1 locus can confer differential susceptibility to the advanced subtypes of age-related macular degeneration. (PubMed id 21122828)1, 4 Sobrin L....Seddon J.M. (Am. J. Ophthalmol. 2011)
    9. Analysis of complement factor H Y402H, LOC387715, HTRA1 polymorphisms and ApoE alleles with susceptibility to age-related macular degeneration in Hungarian patients. (PubMed id 19845562)1, 4 Losonczy G....Balogh I. (Acta Ophthalmol 2011)
    10. Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration. (PubMed id 21665990)1, 4 Yu Y....Seddon J.M. (Hum. Mol. Genet. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 387715 HGNC: 32685 AceView: LOC387715 Ensembl:ENSG00000254636 euGenes: HUgn387715
    ECgene: ARMS2 H-InvDB: ARMS2

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ARMS2 Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/books/NBK1116/?term=ARMS2[genesymbol]

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ARMS2 gene:
    Search GeneIP for patents involving ARMS2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     EMD Millipore Mono- and Polyclonal Antibodies for the study of ARMS2
     Browse Small Molecules at EMD Millipore
     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ARMS2  
     OriGene qPCR primer pairs and template standards for ARMS2   OriGene Protein Over-expression Lysate for ARMS2  
     OriGene MassSpec something-or-other for ARMS2   OriGene clones in human, mouse for ARMS2  
     OriGene qSTAR qPCR primer pairs in human, mouse for ARMS2   OriGene Purified Protein for ARMS2  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ARMS2   OriGene Custom Protein Services for ARMS2  

     
     
     Block miRNA regulation of human, mouse, rat ARMS2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ARMS2
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARMS2 Predesigned siRNA for gene silencing in human, mouse, rat ARMS2
     QuantiFast Probe-based Assays in human, mouse, rat ARMS2 QuantiTect SYBR Green Assays in human, mouse, rat ARMS2
     Custom PCR Arrays for ARMS2 Search Chromatin IP Primers for ARMS2
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARMS2  GeneGlobe Interaction Network for ARMS2
     Regulatory tfbs in ARMS2 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ARMS2 GenScript cDNA clones with any tag delivered in your preferred vector for ARMS2
     GenScript Custom Assay Services for ARMS2 GenScript Custom overexpressing Cell Line Services for ARMS2
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ARMS2
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ARMS2 antibodies
     ARMS2 proteins
     ARMS2 lysates
     Antibodies for ARMS2
     See all of Abcam's Antibodies, Kits and Proteins for ARMS2
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ARMS2
     Antibodies for ARMS2
     ELISAs for ARMS2
     CLIAs for ARMS2



     Browse ESI BIO Cell Lines and PureStem Progenitors for ARMS2
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMS2
     Browse SwitchGear 3'UTR luciferase reporter plasmids for ARMS2
     Browse SwitchGear Promoter luciferase reporter plasmids for ARMS2
     Search ThermoFisher Antibodies for ARMS2
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMS2
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARMS2
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ARMS2
     LSBio Antibodies in human, mouse, rat for ARMS2
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ARMS2
      Search eBioscience for proteins for ARMS2
      Search eBioscience for elisas for ARMS2
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ARMS2 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4