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Aliases for ARMCX6 Gene

Aliases for ARMCX6 Gene

  • Armadillo Repeat Containing, X-Linked 6 2 3 5
  • Protein ARMCX6 3
  • GASP10 3

External Ids for ARMCX6 Gene

Previous GeneCards Identifiers for ARMCX6 Gene

  • GC0XM100676
  • GC0XM100756
  • GC0XM100870
  • GC0XM090660

Summaries for ARMCX6 Gene

GeneCards Summary for ARMCX6 Gene

ARMCX6 (Armadillo Repeat Containing, X-Linked 6) is a Protein Coding gene. An important paralog of this gene is ARMCX3.

Gene Wiki entry for ARMCX6 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMCX6 Gene

Genomics for ARMCX6 Gene

Regulatory Elements for ARMCX6 Gene

Enhancers for ARMCX6 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF101799 0.9 Ensembl ENCODE 12.4 -181.7 -181686 0.6 CTCF MAZ ZNF654 PKNOX1 TRIM22 RAD21 ZBTB40 ZNF518A GABPA PBX2 ARMCX2 ARMCX6 ARMCX3 ARMCX3-AS1 BEX5 GK4P NXF5
GH0XF101622 0.8 ENCODE 6.1 -5.4 -5350 2.6 ATF1 ZNF133 SIN3A ZNF766 ZNF366 CREM EGR2 SP3 USF2 RAD51 BEX5 ARMCX6 ARMCX3 ARMCX3-AS1
GH0XF101616 0.2 ENCODE 4.6 +0.3 326 1.8 GTF2F1 CTCF ATF1 USF1 CREB3L1 MAX DMAP1 RAD21 YY1 E2F1 ARMCX3 ARMCX6 GC0XM101605
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ARMCX6 on UCSC Golden Path with GeneCards custom track

Promoters for ARMCX6 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000480556 501 1800 ATF1 CREB3L1 DMAP1 RAD21 YY1 CREM KLF13 EGR2 ZNF654 ZHX2

Genomic Location for ARMCX6 Gene

101,615,118 bp from pter
101,618,001 bp from pter
2,884 bases
Minus strand

Genomic View for ARMCX6 Gene

Genes around ARMCX6 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMCX6 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMCX6 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMCX6 Gene

Proteins for ARMCX6 Gene

  • Protein details for ARMCX6 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein ARMCX6
    Protein Accession:
    Secondary Accessions:
    • Q9NWJ3

    Protein attributes for ARMCX6 Gene

    300 amino acids
    Molecular mass:
    33019 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAA91387.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for ARMCX6 Gene

Post-translational modifications for ARMCX6 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARMCX6 Gene

No data available for DME Specific Peptides for ARMCX6 Gene

Domains & Families for ARMCX6 Gene

Gene Families for ARMCX6 Gene

Protein Domains for ARMCX6 Gene


Suggested Antigen Peptide Sequences for ARMCX6 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARMCX6: view

No data available for UniProtKB/Swiss-Prot for ARMCX6 Gene

Function for ARMCX6 Gene

genes like me logo Genes that share phenotypes with ARMCX6: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ARMCX6 Gene

Localization for ARMCX6 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ARMCX6 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for ARMCX6 Gene COMPARTMENTS Subcellular localization image for ARMCX6 gene
Compartment Confidence
cytosol 3
mitochondrion 2
nucleus 2
endoplasmic reticulum 1
extracellular 1

Gene Ontology (GO) - Cellular Components for ARMCX6 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ARMCX6: view

Pathways & Interactions for ARMCX6 Gene

SuperPathways for ARMCX6 Gene

No Data Available

Interacting Proteins for ARMCX6 Gene

Gene Ontology (GO) - Biological Process for ARMCX6 Gene


No data available for Pathways by source and SIGNOR curated interactions for ARMCX6 Gene

Transcripts for ARMCX6 Gene

Unigene Clusters for ARMCX6 Gene

Armadillo repeat containing, X-linked 6:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX6 Gene

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3a · 3b ^ 4a · 4b · 4c · 4d · 4e · 4f · 4g ^ 5a · 5b · 5c · 5d · 5e
SP1: - - - - - - -
SP2: -
SP3: - -
SP4: - - - - -
SP5: - - - -
SP6: - - - - - - - - -
SP7: - - -
SP8: - - - - -
SP9: - -

Relevant External Links for ARMCX6 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ARMCX6 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ARMCX6 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for ARMCX6 Gene

This gene is overexpressed in Urine (32.4) and Frontal cortex (26.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for ARMCX6 Gene

Protein tissue co-expression partners for ARMCX6 Gene

NURSA nuclear receptor signaling pathways regulating expression of ARMCX6 Gene:


SOURCE GeneReport for Unigene cluster for ARMCX6 Gene:

genes like me logo Genes that share expression patterns with ARMCX6: view

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ARMCX6 Gene

Orthologs for ARMCX6 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMCX6 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ARMCX6 34 35
  • 98.12 (n)
(Canis familiaris)
Mammalia ARMCX6 34 35
  • 87.58 (n)
(Bos Taurus)
Mammalia ARMCX6 34 35
  • 84.68 (n)
(Mus musculus)
Mammalia Armcx6 34 16 35
  • 78.67 (n)
(Rattus norvegicus)
Mammalia Armcx6 34
  • 78.44 (n)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 27 (a)
(Gallus gallus)
Aves -- 35
  • 24 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 24 (a)
(Danio rerio)
Actinopterygii ARMCX3 35
  • 17 (a)
Species where no ortholog for ARMCX6 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMCX6 Gene

Gene Tree for ARMCX6 (if available)
Gene Tree for ARMCX6 (if available)

Paralogs for ARMCX6 Gene

Paralogs for ARMCX6 Gene

(1) SIMAP similar genes for ARMCX6 Gene using alignment to 1 proteins: Pseudogenes for ARMCX6 Gene

genes like me logo Genes that share paralogs with ARMCX6: view

Variants for ARMCX6 Gene

Sequence variations from dbSNP and Humsavar for ARMCX6 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs111444743 -- 101,615,770(+) TAAAG(A/G)GGGAC intron-variant, reference, missense
rs112269774 -- 101,615,489(+) TACAA(A/T)GCCAA nc-transcript-variant, utr-variant-3-prime
rs112814703 -- 101,615,717(+) GGCCG(G/T)TTATG nc-transcript-variant, utr-variant-3-prime
rs11539307 -- 101,616,325(-) ACACC(A/C)AATAA intron-variant, reference, missense
rs138992392 -- 101,616,422(+) GGGCC(A/G)AGCCA intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ARMCX6 Gene

Variant ID Type Subtype PubMed ID
nsv207 OTHER inversion 15895083
nsv499128 OTHER inversion 21111241
nsv522728 CNV gain 19592680
nsv524711 CNV gain 19592680
nsv7452 OTHER inversion 18451855

Variation tolerance for ARMCX6 Gene

Residual Variation Intolerance Score: 46.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.47; 64.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ARMCX6 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMCX6 Gene

Disorders for ARMCX6 Gene

Relevant External Links for ARMCX6

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ARMCX6 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMCX6 Gene

Publications for ARMCX6 Gene

  1. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. (PMID: 22569362) LA^pez-DomAcnech G. … Soriano E. (Nat Commun 2012) 2 3 64
  2. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3 64
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64

Products for ARMCX6 Gene

Sources for ARMCX6 Gene

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