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Aliases for ARMCX5 Gene

Aliases for ARMCX5 Gene

  • Armadillo Repeat Containing, X-Linked 5 2 3 5
  • GASP5 3

External Ids for ARMCX5 Gene

Previous GeneCards Identifiers for ARMCX5 Gene

  • GC0XP101660
  • GC0XP101854
  • GC0XP091519
  • GC0XP102601

Summaries for ARMCX5 Gene

GeneCards Summary for ARMCX5 Gene

ARMCX5 (Armadillo Repeat Containing, X-Linked 5) is a Protein Coding gene. GO annotations related to this gene include binding. An important paralog of this gene is ARMCX6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMCX5 Gene

Genomics for ARMCX5 Gene

Regulatory Elements for ARMCX5 Gene

Enhancers for ARMCX5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ARMCX5 on UCSC Golden Path with GeneCards custom track

Promoters for ARMCX5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ARMCX5 on UCSC Golden Path with GeneCards custom track

Genomic Location for ARMCX5 Gene

Chromosome:
X
Start:
102,599,168 bp from pter
End:
102,604,159 bp from pter
Size:
4,992 bases
Orientation:
Plus strand

Genomic View for ARMCX5 Gene

Genes around ARMCX5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMCX5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMCX5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMCX5 Gene

Proteins for ARMCX5 Gene

  • Protein details for ARMCX5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P1M9-ARMX5_HUMAN
    Recommended name:
    Armadillo repeat-containing X-linked protein 5
    Protein Accession:
    Q6P1M9
    Secondary Accessions:
    • B3KU88
    • D3DX99
    • Q68DB4
    • Q9BVZ3
    • Q9H969

    Protein attributes for ARMCX5 Gene

    Size:
    558 amino acids
    Molecular mass:
    62346 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARMCX5 Gene

Proteomics data for ARMCX5 Gene at MOPED

Post-translational modifications for ARMCX5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARMCX5 Gene

Domains & Families for ARMCX5 Gene

Gene Families for ARMCX5 Gene

Protein Domains for ARMCX5 Gene

Suggested Antigen Peptide Sequences for ARMCX5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P1M9

UniProtKB/Swiss-Prot:

ARMX5_HUMAN :
  • Contains 3 ARM repeats.
Similarity:
  • Contains 3 ARM repeats.
genes like me logo Genes that share domains with ARMCX5: view

Function for ARMCX5 Gene

Phenotypes for ARMCX5 Gene

genes like me logo Genes that share phenotypes with ARMCX5: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMCX5 Gene

Localization for ARMCX5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARMCX5 Gene COMPARTMENTS Subcellular localization image for ARMCX5 gene
Compartment Confidence
cytosol 3
nucleus 3
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARMCX5 Gene

Pathways & Interactions for ARMCX5 Gene

SuperPathways for ARMCX5 Gene

No Data Available

Interacting Proteins for ARMCX5 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000246174%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000373715%0d%0a9606.ENSP00000083182%0d%0a
Selected Interacting proteins: ENSP00000246174 Q6P1M9-ARMX5_HUMAN for ARMCX5 Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for ARMCX5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARMCX5 Gene

Drugs & Compounds for ARMCX5 Gene

No Compound Related Data Available

Transcripts for ARMCX5 Gene

Unigene Clusters for ARMCX5 Gene

Armadillo repeat containing, X-linked 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX5 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g · 6h · 6i ^ 7a ·
SP1: - - - -
SP2: - - - -
SP3: - - - - - - - - - - - -
SP4: - - - - - - - - - -
SP5: - - - - -
SP6: - - - - -
SP7: - - - -
SP8: - - - - - - - - - - -
SP9: - - - - - - - - - - - -
SP10: - - -
SP11: - - -
SP12: - - - -
SP13: - - - - - - - - - - - - -
SP14: - - -
SP15: - - - - - - - - - - - -
SP16: - - - - - - - - - - - -
SP17: - - - -
SP18: -

ExUns: 7b · 7c · 7d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for ARMCX5 Gene

GeneLoc Exon Structure for
ARMCX5
ECgene alternative splicing isoforms for
ARMCX5

Expression for ARMCX5 Gene

mRNA expression in normal human tissues for ARMCX5 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for ARMCX5 Gene



SOURCE GeneReport for Unigene cluster for ARMCX5 Gene Hs.522729

genes like me logo Genes that share expression patterns with ARMCX5: view

Protein tissue co-expression partners for ARMCX5 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ARMCX5 Gene

Orthologs for ARMCX5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMCX5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ARMCX5 35
  • 84.17 (n)
  • 76.49 (a)
ARMCX5 36
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARMCX5 35
  • 85.48 (n)
  • 79.75 (a)
ARMCX5 36
  • 78 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Armcx5 35
  • 76.24 (n)
  • 61.58 (a)
Armcx5 16
Armcx5 36
  • 56 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ARMCX5 35
  • 99.69 (n)
  • 99.25 (a)
-- 36
  • 25 (a)
ManyToMany
rat
(Rattus norvegicus)
Mammalia LOC102552920 35
  • 76.18 (n)
  • 61.58 (a)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 33 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 36
  • 28 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 26 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ARMCX3 36
  • 21 (a)
OneToMany
Species with no ortholog for ARMCX5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMCX5 Gene

ENSEMBL:
Gene Tree for ARMCX5 (if available)
TreeFam:
Gene Tree for ARMCX5 (if available)

Paralogs for ARMCX5 Gene

Paralogs for ARMCX5 Gene

(3) SIMAP similar genes for ARMCX5 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ARMCX5: view

Variants for ARMCX5 Gene

Sequence variations from dbSNP and Humsavar for ARMCX5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs150556123 -- 102,597,343(+) TCAAG(A/G)AAATC upstream-variant-2KB
rs766921889 -- 102,597,185(+) CTTTG(G/T)ATCTT upstream-variant-2KB
rs377744591 -- 102,597,198(+) AAATG(A/T)CTGAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for ARMCX5 Gene

Variant ID Type Subtype PubMed ID
nsv526716 CNV Gain 19592680

Variation tolerance for ARMCX5 Gene

Residual Variation Intolerance Score: 78.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.65; 13.93% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for ARMCX5 Gene

Disorders for ARMCX5 Gene

Relevant External Links for ARMCX5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ARMCX5

No disorders were found for ARMCX5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMCX5 Gene

Publications for ARMCX5 Gene

  1. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. (PMID: 22569362) LA^pez-DomAcnech G. … Soriano E. (Nat Commun 2012) 2 3 67
  2. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3
  3. TRIM65 regulates microRNA activity by ubiquitination of TNRC6. (PMID: 24778252) Li S. … Dorf M.E. (Proc. Natl. Acad. Sci. U.S.A. 2014) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells. (PMID: 23284306) Xie L. … Green M.R. (PLoS Genet. 2012) 3

Products for ARMCX5 Gene

Sources for ARMCX5 Gene

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