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Aliases for ARMCX5 Gene

Aliases for ARMCX5 Gene

  • Armadillo Repeat Containing, X-Linked 5 2 3 5
  • Armadillo Repeat-Containing X-Linked Protein 5 3
  • GASP5 3

External Ids for ARMCX5 Gene

Previous GeneCards Identifiers for ARMCX5 Gene

  • GC0XP101660
  • GC0XP101854
  • GC0XP091519
  • GC0XP102601

Summaries for ARMCX5 Gene

GeneCards Summary for ARMCX5 Gene

ARMCX5 (Armadillo Repeat Containing, X-Linked 5) is a Protein Coding gene. GO annotations related to this gene include binding. An important paralog of this gene is GPRASP2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMCX5 Gene

Genomics for ARMCX5 Gene

Regulatory Elements for ARMCX5 Gene


Promoters for ARMCX5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000480584 733 2599 PKNOX1 ATF1 CREB3L1 ARID4B SIN3A DMAP1 ZNF48 YY1 ZNF143 SP3

Genomic Location for ARMCX5 Gene

Chromosome:
X
Start:
102,599,168 bp from pter
End:
102,604,159 bp from pter
Size:
4,992 bases
Orientation:
Plus strand

Genomic View for ARMCX5 Gene

Genes around ARMCX5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMCX5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMCX5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMCX5 Gene

Proteins for ARMCX5 Gene

  • Protein details for ARMCX5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P1M9-ARMX5_HUMAN
    Recommended name:
    Armadillo repeat-containing X-linked protein 5
    Protein Accession:
    Q6P1M9
    Secondary Accessions:
    • B3KU88
    • D3DX99
    • Q68DB4
    • Q9BVZ3
    • Q9H969

    Protein attributes for ARMCX5 Gene

    Size:
    558 amino acids
    Molecular mass:
    62346 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARMCX5 Gene

Post-translational modifications for ARMCX5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARMCX5 Gene

Domains & Families for ARMCX5 Gene

Gene Families for ARMCX5 Gene

Protein Domains for ARMCX5 Gene

Suggested Antigen Peptide Sequences for ARMCX5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6P1M9

UniProtKB/Swiss-Prot:

ARMX5_HUMAN :
  • Contains 3 ARM repeats.
Similarity:
  • Contains 3 ARM repeats.
genes like me logo Genes that share domains with ARMCX5: view

Function for ARMCX5 Gene

Gene Ontology (GO) - Molecular Function for ARMCX5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ARMCX5: view

Phenotypes for ARMCX5 Gene

genes like me logo Genes that share phenotypes with ARMCX5: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMCX5 Gene

Localization for ARMCX5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARMCX5 Gene COMPARTMENTS Subcellular localization image for ARMCX5 gene
Compartment Confidence
cytosol 3
nucleus 3
plasma membrane 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARMCX5 Gene

Pathways & Interactions for ARMCX5 Gene

SuperPathways for ARMCX5 Gene

No Data Available

Interacting Proteins for ARMCX5 Gene

Gene Ontology (GO) - Biological Process for ARMCX5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARMCX5 Gene

Transcripts for ARMCX5 Gene

Unigene Clusters for ARMCX5 Gene

Armadillo repeat containing, X-linked 5:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX5 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g · 6h · 6i ^ 7a ·
SP1: - - - -
SP2: - - - -
SP3: - - - - - - - - - - - -
SP4: - - - - - - - - - -
SP5: - - - - -
SP6: - - - - -
SP7: - - - -
SP8: - - - - - - - - - - -
SP9: - - - - - - - - - - - -
SP10: - - -
SP11: - - -
SP12: - - - -
SP13: - - - - - - - - - - - - -
SP14: - - -
SP15: - - - - - - - - - - - -
SP16: - - - - - - - - - - - -
SP17: - - - -
SP18: -

ExUns: 7b · 7c · 7d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for ARMCX5 Gene

GeneLoc Exon Structure for
ARMCX5
ECgene alternative splicing isoforms for
ARMCX5

Expression for ARMCX5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for ARMCX5 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for ARMCX5 Gene



Protein tissue co-expression partners for ARMCX5 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ARMCX5 Gene:

ARMCX5

SOURCE GeneReport for Unigene cluster for ARMCX5 Gene:

Hs.522729
genes like me logo Genes that share expression patterns with ARMCX5: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ARMCX5 Gene

Orthologs for ARMCX5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMCX5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARMCX5 34
  • 99.69 (n)
-- 35
  • 25 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia ARMCX5 34 35
  • 85.48 (n)
cow
(Bos Taurus)
Mammalia ARMCX5 34 35
  • 84.17 (n)
mouse
(Mus musculus)
Mammalia Armcx5 34 16 35
  • 76.24 (n)
rat
(Rattus norvegicus)
Mammalia LOC102552920 34
  • 76.18 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 33 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 28 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 26 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ARMCX3 35
  • 21 (a)
OneToMany
Species where no ortholog for ARMCX5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMCX5 Gene

ENSEMBL:
Gene Tree for ARMCX5 (if available)
TreeFam:
Gene Tree for ARMCX5 (if available)

Paralogs for ARMCX5 Gene

Paralogs for ARMCX5 Gene

(3) SIMAP similar genes for ARMCX5 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ARMCX5: view

Variants for ARMCX5 Gene

Sequence variations from dbSNP and Humsavar for ARMCX5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs112199379 -- 102,599,991(+) AAAAA(A/T)GATCT intron-variant
rs112318694 -- 102,602,490(+) GGGTC(A/G)GTACT intron-variant, reference, missense
rs112568002 -- 102,599,982(+) CAATT(A/G/T)AAAAA intron-variant
rs112924225 -- 102,597,635(+) GAACA(A/G)CATGG upstream-variant-2KB
rs112989637 -- 102,602,440(+) AGAAC(A/G)CAGTA intron-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for ARMCX5 Gene

Variant ID Type Subtype PubMed ID
nsv526716 CNV gain 19592680

Variation tolerance for ARMCX5 Gene

Residual Variation Intolerance Score: 78.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.65; 13.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ARMCX5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARMCX5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMCX5 Gene

Disorders for ARMCX5 Gene

Relevant External Links for ARMCX5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ARMCX5

No disorders were found for ARMCX5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMCX5 Gene

Publications for ARMCX5 Gene

  1. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. (PMID: 22569362) LA^pez-DomAcnech G. … Soriano E. (Nat Commun 2012) 2 3 64
  2. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3 64
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64

Products for ARMCX5 Gene

Sources for ARMCX5 Gene

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