ARMCX5 Gene
protein-coding GIFtS: 40
GCID: GC0XP101854
|
|
armadillo repeat containing, X-linked 5
| |
Aliases
for ARMCX5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Armadillo Repeat Containing, X-Linked 51 2 | | FLJ129691 | | Armadillo Repeat-Containing X-Linked Protein 52 |
Export aliases for ARMCX5 gene to outside databasesPrevious GC identifers: GC0XP101660 GC0XP091519 |
Summaries
for ARMCX5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for ARMCX5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011651.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARMCX5 gene promoter:
Bach1 GR TBP Pax-6 SRY TFIID FOXJ2 (long isoform) GR-alpha FOXJ2 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARMCX5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARMCX5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq22.1-q22.3 Ensembl cytogenetic band: Xq22.1 HGNC cytogenetic band: Xq22.1-q22.3ARMCX5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP101854: view genomic region
(about GC identifiers)
Start:
|
101,854,096 bp from pter |
End:
|
101,969,594 bp from pter |
Size:
|
115,499 bases |
Orientation:
|
plus strand |
|
Proteins
for ARMCX5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ARMX5_HUMAN, Q6P1M9 (See
protein sequence)Recommended Name: Armadillo repeat-containing X-linked protein 5 Size: 558 amino acids; 62346 Da
Secondary accessions: B3KU88 D3DX99 Q68DB4 Q9BVZ3 Q9H969Explore the universe of human proteins at neXtProt for ARMCX5: NX_Q6P1M9
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6P1M9
ARMCX5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (6 alternative transcripts):
NP_001161950.1 NP_001161951.1 NP_001161952.1 NP_001161954.1 NP_001161957.1 NP_073749.2
ENSEMBL proteins: ENSP00000246174 ENSP00000361827 ENSP00000439001 ENSP00000446385 ENSP00000445851
Human Recombinant Protein Products:
ARMCX5 Antibody Products:
Assay Products for ARMCX5: |
Protein
Domains /
Families
for ARMCX5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARMCX5 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q6P1M9ProtoNet protein and cluster: Q6P1M9 UniProtKB/Swiss-Prot: ARMX5_HUMAN, Q6P1M9Similarity: Contains 3 ARM repeats |
Function
for ARMCX5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARMCX5 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARMCX5 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for ARMCX5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMCX5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMCX5 |
|
Pathways & Interactions
for ARMCX5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARMCX5
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for ARMCX5 (ENSP000002461744) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for ARMCX5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ARMCX5
Search CenterWatch for drugs/clinical trials and news about ARMCX5 / ARMX5
|
Transcripts
for ARMCX5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARMCX5 gene (6 alternative transcripts): NM_001168478.1 NM_001168479.1 NM_001168480.1 NM_001168482.1 NM_001168485.1 NM_022838.3 Unigene Cluster for ARMCX5: Armadillo repeat containing, X-linked 5 Hs.522729 [show with all ESTs]Unigene Representative Sequence: NM_00119981815 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000246174(uc004ejg.3 uc022cax.1) ENST00000473968 ENST00000465548
ENST00000477663 ENST00000460026 ENST00000466616 ENST00000475738 ENST00000476910
ENST00000486740 ENST00000479502 ENST00000460793 ENST00000372742 ENST00000537008(uc022caw.1)
ENST00000541409 ENST00000536530(uc022caz.1 uc022cba.1 uc004ejh.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARMCX5 (see all 8)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARMCX5 (see all 6)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 6): ARMCX5 (NM_022838) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARMCX5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMCX5 |
Additional cDNA sequence: AK023031.1 AK092981.1 AK094646.1 AK096067.1 AK096692.1 AL832187.1 BC000792.1 BC013576.1 BC022066.2 BC047679.1 BC050678.1 BC058904.1 BC064983.1 22 DOTS entries: DT.99941501 DT.121305738 DT.91754972 DT.441264 DT.95263615 DT.95375602 DT.121305830 DT.212424 DT.100027519 DT.100784510 DT.121305832 DT.442728 DT.100821796 DT.91963431 DT.97845890 DT.433306 DT.95375599 DT.100784512 DT.121305856 DT.121305622 DT.121305708 DT.75152121 24/206 AceView cDNA sequences (see all 206): AA323438 AU129588 BI962806 BU622642 T17057 BC000792 AI472825 BX489726 AA282644 AU152883 BM727939 AL537480 AA336707 AA622241 BC047679 AI498726 BQ012171 AV727869 AA558940 AK096692 AA992143 T03673 AK023031 CD243257
GeneLoc Exon Structure
5/18 Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX5 (see all 18) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | · | 3c | · | 3d | · | 3e | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f | · | 6g | · | 6h | · | 6i | ^ | 7a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | - | | | | | | | | - | | | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | - | | | | - | | | | - | | | | | | - | | - | | - | | - | | - | | - | | - | | | | |
| SP5: | | | | | | | | | | | | | | | - | | | | | | | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 7b | · | 7c | · | 7d |
|---|
|
| SP1: | | | | | | | |
| SP2: | | | | | | | |
| SP3: | | | | | | | |
| SP4: | | | | | | | |
| SP5: | | | | | | |
ECgene alternative splicing isoforms for ARMCX5
|
Expression
for ARMCX5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARMCX5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTAAAACTGG
About this image
See ARMCX5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARMCX5
SOURCE GeneReport for Unigene cluster: Hs.522729
SABiosciences Custom PCR Arrays for ARMCX5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARMCX5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat ARMCX5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARMCX5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARMCX5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMCX5 |
Orthologs
for ARMCX5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for ARMCX5 gene from 3/7 species (see all 7) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
ARMC106 |
Uncharacterized protein |
28(a) |
1 → many |
1(13884450-13891606) |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
31(a) |
1 → many |
5(95306234-95312068) |
zebrafish
(Danio rerio) |
Actinopterygii |
CR391963.36 |
-- |
21(a) |
1 → many |
25(19368324-19378456) |
ENSEMBL Gene Tree for ARMCX5 (if available)
TreeFam Gene Tree for ARMCX5 (if available) |
Paralogs
for ARMCX5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARMCX5 gene
- ARMCX42 GPRASP22 ARMCX12 BHLHB92 ARMCX22 GPRASP12 ARMCX62 ARMC102
- ARMCX32
3 SIMAP similar genes for ARMCX5 using alignment to 1 protein entry: ARMX5_HUMAN:ARMCX3 BHLHB9 ARMCX4
ARMCX5 for paralogs About GeneDecksing
|
Genomic Variants
for ARMCX5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARMCX5 (101854096 - 101969594 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARMCX5: --
Locus Specific Mutation Databases (LSDB): ARMCX5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARMCX5 |
|
Disorders
/ Diseases
for ARMCX5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for ARMCX5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARMCX5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with ARMCX5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions. (PubMed id 15342556)1 Suzuki Y.... Sugano S. (2004)
|
External Searches for ARMCX5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARMCX5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARMCX5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ARMCX5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ARMCX5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for ARMCX5 gene:
Search GeneIP for patents involving ARMCX5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ARMCX5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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