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Aliases for ARMCX5 Gene

Aliases for ARMCX5 Gene

  • Armadillo Repeat Containing, X-Linked 5 2 3 5
  • Armadillo Repeat-Containing X-Linked Protein 5 3
  • GASP5 3

External Ids for ARMCX5 Gene

Previous GeneCards Identifiers for ARMCX5 Gene

  • GC0XP101660
  • GC0XP101854
  • GC0XP091519
  • GC0XP102601

Summaries for ARMCX5 Gene

GeneCards Summary for ARMCX5 Gene

ARMCX5 (Armadillo Repeat Containing, X-Linked 5) is a Protein Coding gene. GO annotations related to this gene include binding. An important paralog of this gene is ARMCX4.

Additional gene information for ARMCX5 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMCX5 Gene

Genomics for ARMCX5 Gene

Regulatory Elements for ARMCX5 Gene

Enhancers for ARMCX5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XH102658 1.4 FANTOM5 ENCODE 13.6 +60.2 60187 2 HDAC1 ATF1 FOXA2 ARID4B SIN3A YY1 FOS ATF7 CREM HCFC1 GPRASP1 LINC00630 ARMCX5 ENSG00000239407 TCEAL3-AS1 TCEAL9 BHLHB9 ENSG00000270050
GH0XH103151 1.2 Ensembl ENCODE 11.1 +553.1 553141 1 ARNT FEZF1 GLI4 BRCA1 ZNF2 ZBTB7B TCF12 ZNF121 GLIS2 ATF7 GPRASP1 BEX4 TCEAL3 ELF2P1 TMSB15B ZCCHC18 GPRASP2 BEX3 TCEAL7 TCEAL1
GH0XH102720 0.9 ENCODE 13.5 +121.6 121613 1 HDAC1 ATF1 SIN3A ZEB1 YY1 RCOR1 FOS CREM HCFC1 USF2 MORF4L2-AS1 LINC00630 ARMCX5 ENSG00000239407 TCEAL3-AS1 TCEAL9 BEX4 BHLHB9
GH0XH103423 0.6 ENCODE 11.8 +825.1 825052 1 ZNF680 ZFP64 ZC3H11A ZNF140 ZNF518A ZNF697 ZNF555 PRDM12 BEX4 MORF4L2-AS1 LINC00630 BEX3 ARMCX5 ENSG00000239407 PIR37216 ENSG00000281091 LL0XNC01-250H12.3
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ARMCX5 on UCSC Golden Path with GeneCards custom track

Promoters for ARMCX5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000247657 633 2399 PKNOX1 ATF1 ARID4B SIN3A DMAP1 YY1 ZNF143 ZNF207 ATF7 RUNX3

Genomic Location for ARMCX5 Gene

Chromosome:
X
Start:
102,599,168 bp from pter
End:
102,604,159 bp from pter
Size:
4,992 bases
Orientation:
Plus strand

Genomic View for ARMCX5 Gene

Genes around ARMCX5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMCX5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMCX5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMCX5 Gene

Proteins for ARMCX5 Gene

  • Protein details for ARMCX5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6P1M9-ARMX5_HUMAN
    Recommended name:
    Armadillo repeat-containing X-linked protein 5
    Protein Accession:
    Q6P1M9
    Secondary Accessions:
    • B3KU88
    • D3DX99
    • Q68DB4
    • Q9BVZ3
    • Q9H969

    Protein attributes for ARMCX5 Gene

    Size:
    558 amino acids
    Molecular mass:
    62346 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARMCX5 Gene

Post-translational modifications for ARMCX5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for ARMCX5 Gene

Domains & Families for ARMCX5 Gene

Gene Families for ARMCX5 Gene

HGNC:
Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for ARMCX5 Gene

Suggested Antigen Peptide Sequences for ARMCX5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARMCX5: view

No data available for UniProtKB/Swiss-Prot for ARMCX5 Gene

Function for ARMCX5 Gene

Gene Ontology (GO) - Molecular Function for ARMCX5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with ARMCX5: view

Phenotypes for ARMCX5 Gene

genes like me logo Genes that share phenotypes with ARMCX5: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMCX5 Gene

Localization for ARMCX5 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for ARMCX5 gene
Compartment Confidence
nucleus 3
cytosol 3
plasma membrane 2

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nuclear speckles (2)
See all subcellular structures

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARMCX5 Gene

Pathways & Interactions for ARMCX5 Gene

SuperPathways for ARMCX5 Gene

No Data Available

Interacting Proteins for ARMCX5 Gene

Gene Ontology (GO) - Biological Process for ARMCX5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARMCX5 Gene

Drugs & Compounds for ARMCX5 Gene

No Compound Related Data Available

Transcripts for ARMCX5 Gene

Unigene Clusters for ARMCX5 Gene

Armadillo repeat containing, X-linked 5:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX5 Gene

ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d ^ 3a · 3b · 3c · 3d · 3e ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e · 6f · 6g · 6h · 6i ^ 7a ·
SP1: - - - -
SP2: - - - -
SP3: - - - - - - - - - - - -
SP4: - - - - - - - - - -
SP5: - - - - -
SP6: - - - - -
SP7: - - - -
SP8: - - - - - - - - - - -
SP9: - - - - - - - - - - - -
SP10: - - -
SP11: - - -
SP12: - - - -
SP13: - - - - - - - - - - - - -
SP14: - - -
SP15: - - - - - - - - - - - -
SP16: - - - - - - - - - - - -
SP17: - - - -
SP18: -

ExUns: 7b · 7c · 7d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:
SP13:
SP14:
SP15:
SP16:
SP17:
SP18:

Relevant External Links for ARMCX5 Gene

GeneLoc Exon Structure for
ARMCX5
ECgene alternative splicing isoforms for
ARMCX5

Expression for ARMCX5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for ARMCX5 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ARMCX5 Gene



Protein tissue co-expression partners for ARMCX5 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of ARMCX5 Gene:

ARMCX5

SOURCE GeneReport for Unigene cluster for ARMCX5 Gene:

Hs.522729

Evidence on tissue expression from TISSUES for ARMCX5 Gene

  • Nervous system(3.7)
genes like me logo Genes that share expression patterns with ARMCX5: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARMCX5 Gene

Orthologs for ARMCX5 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMCX5 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARMCX5 33
  • 99.69 (n)
-- 34
  • 25 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia ARMCX5 33 34
  • 85.48 (n)
cow
(Bos Taurus)
Mammalia ARMCX5 33 34
  • 84.17 (n)
mouse
(Mus musculus)
Mammalia Armcx5 33 16 34
  • 76.24 (n)
rat
(Rattus norvegicus)
Mammalia LOC102552920 33
  • 76.18 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 33 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 28 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 26 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ARMCX3 34
  • 21 (a)
OneToMany
Species where no ortholog for ARMCX5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMCX5 Gene

ENSEMBL:
Gene Tree for ARMCX5 (if available)
TreeFam:
Gene Tree for ARMCX5 (if available)

Paralogs for ARMCX5 Gene

Paralogs for ARMCX5 Gene

(3) SIMAP similar genes for ARMCX5 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with ARMCX5: view

Variants for ARMCX5 Gene

Sequence variations from dbSNP and Humsavar for ARMCX5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1000107889 -- 102,600,998(+) GAAAT(A/T)ACGAA intron-variant, utr-variant-5-prime
rs1000634112 -- 102,603,207(+) CTGTT(A/G)TGATT intron-variant, reference, missense
rs1000666618 -- 102,602,551(+) GTCCT(A/T)TGCCA intron-variant, reference, missense
rs1000714514 -- 102,603,990(+) ATTGT(A/G)CTATA intron-variant, utr-variant-3-prime
rs1001230523 -- 102,604,500(+) ATAAA(A/G)TGTCT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ARMCX5 Gene

Variant ID Type Subtype PubMed ID
nsv526716 CNV gain 19592680

Variation tolerance for ARMCX5 Gene

Residual Variation Intolerance Score: 78.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.65; 13.93% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ARMCX5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARMCX5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMCX5 Gene

Disorders for ARMCX5 Gene

Relevant External Links for ARMCX5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ARMCX5

No disorders were found for ARMCX5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMCX5 Gene

Publications for ARMCX5 Gene

  1. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. (PMID: 22569362) López-Doménech G … Soriano E (Nature communications 2012) 2 3 60
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 60
  3. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter EE … Ponting CP (BMC evolutionary biology 2005) 2 3 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60

Products for ARMCX5 Gene

Sources for ARMCX5 Gene

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