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Aliases for ARMCX4 Gene

Aliases for ARMCX4 Gene

  • Armadillo Repeat Containing, X-Linked 4 2 3
  • Armadillo Repeat Containing, X-Linked 4 Pseudogene 2 3
  • Armadillo Repeat-Containing X-Linked Protein 4 3
  • Chromosome X Open Reading Frame 35 2
  • CXorf35 3
  • GASP4 3

External Ids for ARMCX4 Gene

Previous Symbols for ARMCX4 Gene

  • CXorf35

Summaries for ARMCX4 Gene

Entrez Gene Summary for ARMCX4 Gene

  • The product of this gene belongs to the armadillo repeat-containing family of proteins, which interact with other proteins in a variety of cellular processes. The function of this family member is currently unknown. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]

GeneCards Summary for ARMCX4 Gene

ARMCX4 (Armadillo Repeat Containing, X-Linked 4) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMCX4 Gene

Genomics for ARMCX4 Gene

Genomic Location for ARMCX4 Gene

Start:
101,418,263 bp from pter
End:
101,535,988 bp from pter
Size:
117,726 bases
Orientation:
Plus strand

Genomic View for ARMCX4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARMCX4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMCX4 Gene

No data available for Regulatory Elements for ARMCX4 Gene

Proteins for ARMCX4 Gene

  • Protein details for ARMCX4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5H9R4-ARMX4_HUMAN
    Recommended name:
    Armadillo repeat-containing X-linked protein 4
    Protein Accession:
    Q5H9R4
    Secondary Accessions:
    • A8K928
    • B3KXA4
    • Q5H9K8
    • Q8N8D6

    Protein attributes for ARMCX4 Gene

    Size:
    360 amino acids
    Molecular mass:
    39406 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ARMCX4 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARMCX4 Gene

Proteomics data for ARMCX4 Gene at MOPED

Post-translational modifications for ARMCX4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARMCX4 Gene

No data available for DME Specific Peptides for ARMCX4 Gene

Domains for ARMCX4 Gene

Gene Families for ARMCX4 Gene

HGNC:
  • ARMC :Armadillo repeat containing

Protein Domains for ARMCX4 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for ARMCX4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARMCX4: view

No data available for UniProtKB/Swiss-Prot for ARMCX4 Gene

Function for ARMCX4 Gene

Gene Ontology (GO) - Molecular Function for ARMCX4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding --
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with ARMCX4: view

Phenotypes for ARMCX4 Gene

GenomeRNAi human phenotypes for ARMCX4:
genes like me logo Genes that share phenotypes with ARMCX4: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for ARMCX4 Gene

Localization for ARMCX4 Gene

Subcellular locations from UniProtKB/Swiss-Prot for ARMCX4 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARMCX4 Gene COMPARTMENTS Subcellular localization image for ARMCX4 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for ARMCX4 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with ARMCX4: view

Pathways for ARMCX4 Gene

SuperPathways for ARMCX4 Gene

No Data Available

Interacting Proteins for ARMCX4 Gene

Gene Ontology (GO) - Biological Process for ARMCX4 Gene

None

No data available for Pathways by source for ARMCX4 Gene

Transcripts for ARMCX4 Gene

mRNA/cDNA for ARMCX4 Gene

(2) REFSEQ mRNAs :
(14) Additional mRNA sequences :
(10) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ARMCX4 Gene

Armadillo repeat containing, X-linked 4:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX4 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10a · 10b
SP1: - -
SP2: - - - - - - - -
SP3: - - - - -
SP4: -
SP5:
SP6:
SP7: - - - - -
SP8: - - - -
SP9:

Relevant External Links for ARMCX4 Gene

GeneLoc Exon Structure for
ARMCX4
ECgene alternative splicing isoforms for
ARMCX4

Expression for ARMCX4 Gene

mRNA expression in normal human tissues for ARMCX4 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ARMCX4 Gene

SOURCE GeneReport for Unigene cluster for ARMCX4 Gene Hs.729062

genes like me logo Genes that share expressions with ARMCX4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for ARMCX4 Gene

Orthologs for ARMCX4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ARMCX4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARMCX4 36
  • 69 (a)
OneToOne
LOC101058973 35
  • 98.67 (n)
  • 97.52 (a)
cow
(Bos Taurus)
Mammalia ARMCX4 35
  • 78.92 (n)
  • 64.75 (a)
ARMCX4 36
  • 54 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARMCX4 35
  • 80.85 (n)
  • 67.41 (a)
ARMCX4 36
  • 61 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Armcx4 35
  • 78.6 (n)
  • 64.97 (a)
Armcx4 36
  • 51 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Armcx4 35
  • 76.05 (n)
  • 62.9 (a)
Species with no ortholog for ARMCX4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ARMCX4 Gene

ENSEMBL:
Gene Tree for ARMCX4 (if available)
TreeFam:
Gene Tree for ARMCX4 (if available)

Paralogs for ARMCX4 Gene

Selected SIMAP similar genes for ARMCX4 Gene using alignment to 4 proteins:

genes like me logo Genes that share paralogs with ARMCX4: view

No data available for Paralogs for ARMCX4 Gene

Variants for ARMCX4 Gene

Sequence variations from dbSNP and Humsavar for ARMCX4 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs949436 -- 101,471,216(+) tgtac(A/T)atatg intron-variant
rs957429 -- 101,486,267(-) TCTTC(A/T)TTGGT upstream-variant-2KB, intron-variant
rs957430 -- 101,486,224(-) GTAAG(G/T)AAAAT upstream-variant-2KB, intron-variant
rs959507 -- 101,495,577(+) GTCTA(G/T)AGCTG utr-variant-3-prime, intron-variant
rs963618 -- 101,488,050(+) GTGTA(C/T)TGCCA utr-variant-5-prime, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for ARMCX4 Gene

Variant ID Type Subtype PubMed ID
esv2740356 CNV Deletion 23290073
esv2675772 CNV Deletion 23128226
esv2740357 CNV Deletion 23290073
esv1282718 CNV Insertion 17803354
esv2740358 CNV Deletion 23290073
esv2479084 CNV Insertion 19546169
esv1096204 CNV Insertion 17803354

Relevant External Links for ARMCX4 Gene

HapMap Linkage Disequilibrium report
ARMCX4
Locus Specific Mutation Databases (LSDB)
ARMCX4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMCX4 Gene

Disorders for ARMCX4 Gene

No disorders were found for ARMCX4 Gene.

No data available for UniProtKB/Swiss-Prot for ARMCX4 Gene

Publications for ARMCX4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4
  3. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PMID: 16221301) Winter E.E. … Ponting C.P. (BMC Evol. Biol. 2005) 2 3
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 3 4
  5. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. (PMID: 22569362) LA^pez-DomAcnech G. … Soriano E. (Nat Commun 2012) 2 3

Products for ARMCX4 Gene

Sources for ARMCX4 Gene

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