Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ARMCX3 Gene

protein-coding   GIFtS: 50
GCID: GC0XP100878

Armadillo Repeat Containing, X-Linked 3

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Armadillo Repeat Containing, X-Linked 31 2     Arm Protein Lost In Epithelial Cancers, X Chromosome, 32
ALEX32 3 5     Armadillo Repeat-Containing X-Linked Protein 32
ARM Protein Lost In Epithelial Cancers On Chromosome X 32 3     dJ545K15.22
1200004E24Rik2     Protein ALEX33
GASP62     

External Ids:    HGNC: 240651   Entrez Gene: 515662   Ensembl: ENSG000001024017   OMIM: 3003645   UniProtKB: Q9UH623   

Export aliases for ARMCX3 gene to outside databases

Previous GC identifers: GC0XP099650 GC0XP100684 GC0XP100764 GC0XP090685


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for ARMCX3 Gene:
This gene encodes a member of the ALEX family of proteins which may play a role in tumor suppression. The encoded
protein contains a potential N-terminal transmembrane domain and a single Armadillo (arm) repeat. Other proteins
containing the arm repeat are involved in development, maintenance of tissue integrity, and tumorigenesis. This
gene is closely localized with other family members on the X chromosome. Three transcript variants encoding the
same protein have been identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for ARMCX3 Gene:
ARMCX3 (armadillo repeat containing, X-linked 3) is a protein-coding gene. An important paralog of this gene is GPRASP2.

Gene Wiki entry for ARMCX3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011651.18  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARMCX3 gene promoter:
         N-Myc   FOXO4   HOXA5   IRF-1   Gfi-1   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARMCX3 promoter sequence
   Search Chromatin IP Primers for ARMCX3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARMCX3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.1   Ensembl cytogenetic band:  Xq22.1   HGNC cytogenetic band: Xq22.1

ARMCX3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARMCX3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP100878:  view genomic region     (about GC identifiers)

Start:
100,877,787 bp from pter      End:
100,882,833 bp from pter
Size:
5,047 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: ARMX3_HUMAN, Q9UH62 (See protein sequence)
Recommended Name: Armadillo repeat-containing X-linked protein 3  
Size: 379 amino acids; 42501 Da
Secondary accessions: Q53HC6 Q7LCF5 Q9NPE4

Explore the universe of human proteins at neXtProt for ARMCX3: NX_Q9UH62

Explore proteomics data for ARMCX3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys170, Lys182
  • Modification sites at PhosphoSitePlus

  • See ARMCX3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_057691.1  NP_808816.1  NP_808817.1  

    ENSEMBL proteins: 
     ENSP00000340672   ENSP00000454483   ENSP00000457997   ENSP00000454251   ENSP00000439032  

    ARMCX3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ARMCX3
    OriGene Protein Over-expression Lysate for ARMCX3
    OriGene MassSpec for ARMCX3
    OriGene Custom Protein Services for ARMCX3
    GenScript Custom Purified and Recombinant Proteins Services for ARMCX3
    Novus Biologicals ARMCX3 Proteins
    Novus Biologicals ARMCX3 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ARMCX3

     
    Search eBioscience for Proteins for ARMCX3 

    ARMCX3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for ARMCX3
    OriGene Custom Antibody Services for ARMCX3
    Novus Biologicals ARMCX3 Antibodies
    Abcam antibodies for ARMCX3
    Cloud-Clone Corp. Antibodies for ARMCX3
    Search ThermoFisher Antibodies for ARMCX3
    LSBio Antibodies in human, mouse, rat for ARMCX3

    ARMCX3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ARMCX3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ARMCX3
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ARMCX3
    Cloud-Clone Corp. CLIAs for ARMCX3
    Search eBioscience for ELISAs for ARMCX3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ARMC: Armadillo repeat containing

    4 InterPro protein domains:
     IPR011989 ARM-like
     IPR000225 Armadillo
     IPR006911 ARM-rpt_dom
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9UH62

    ProtoNet protein and cluster: Q9UH62

    UniProtKB/Swiss-Prot: ARMX3_HUMAN, Q9UH62
    Similarity: Contains 3 ARM repeats


    Find genes that share domains with ARMCX3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
         
    Find genes that share ontologies with ARMCX3           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARMCX3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ARMCX3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARMCX3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARMCX3

    miRNA
    Products:
        
    miRTarBase miRNAs that target ARMCX3:
    hsa-mir-21-5p (MIRT030836), hsa-mir-10a-5p (MIRT047635)

    Block miRNA regulation of human, mouse, rat ARMCX3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARMCX3 (see all 31):
    hsa-miR-548j hsa-miR-3128 hsa-miR-548i hsa-miR-488 hsa-miR-624 hsa-miR-27b* hsa-miR-548a-5p hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidARMCX3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ARMCX3
    Predesigned siRNA for gene silencing in human, mouse, rat ARMCX3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ARMCX3

    Clone
    Products:
         
    OriGene clones in human, mouse for ARMCX3 (see all 19)
    OriGene ORF clones in mouse, rat for ARMCX3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ARMCX3 (NM_177947)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMCX3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMCX3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ARMCX3
    Browse ESI BIO Cell Lines and PureStem Progenitors for ARMCX3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMCX3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    ARMX3_HUMAN, Q9UH62: Membrane; Single-pass membrane protein (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion2
    cytosol1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0031307integral component of mitochondrial outer membrane IEA--

    Find genes that share ontologies with ARMCX3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARMCX3
    Interactions:

        Search GeneGlobe Interaction Network for ARMCX3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for ARMCX3 (Q9UH622, 3 ENSP000003406724) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLTCQ006102, 3MINT-65733 I2D: score=5 
    IMMTQ168912, 3MINT-65734 I2D: score=5 
    GPN1Q9HCN43, ENSP000002647184I2D: score=1 STRING: ENSP00000264718
    MAF1Q9H0633, ENSP000003186044I2D: score=2 STRING: ENSP00000318604
    RPAP2Q8IXW53I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0034613cellular protein localization IEA--
    GO:0045944positive regulation of transcription from RNA polymerase II promoter IEA--

    Find genes that share ontologies with ARMCX3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARMCX3 (ARMX3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ARMCX3 gene (3 alternative transcripts): 
    NM_016607.3  NM_177947.2  NM_177948.2  

    Unigene Cluster for ARMCX3:

    Armadillo repeat containing, X-linked 3
    Hs.592225  [show with all ESTs]
    Unigene Representative Sequence: CR933656
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000341189(uc004ehz.1 uc004eia.1 uc004eib.1) ENST00000471229
    ENST00000491568 ENST00000479298 ENST00000477980 ENST00000467808 ENST00000537169(uc004eic.1)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ARMCX3 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARMCX3 (see all 31):
    hsa-miR-548j hsa-miR-3128 hsa-miR-548i hsa-miR-488 hsa-miR-624 hsa-miR-27b* hsa-miR-548a-5p hsa-miR-548d-5p
    SwitchGear 3'UTR luciferase reporter plasmidARMCX3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ARMCX3
    Predesigned siRNA for gene silencing in human, mouse, rat ARMCX3
    Clone
    Products:
         
    OriGene clones in human, mouse for ARMCX3 (see all 19)
    OriGene ORF clones in mouse, rat for ARMCX3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ARMCX3 (NM_177947)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMCX3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMCX3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ARMCX3
    OriGene qSTAR qPCR primer pairs in human, mouse for ARMCX3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARMCX3
      QuantiTect SYBR Green Assays in human, mouse, rat ARMCX3
      QuantiFast Probe-based Assays in human, mouse, rat ARMCX3

    Additional mRNA sequence: 

    AB039669.1 AF211175.1 AK222655.1 AK291225.1 AY359079.1 BC005194.1 BX647802.1 CR933656.1 
    XR_158967.1 XR_159547.1 XR_172407.1 

    15 DOTS entries:

    DT.91752916  DT.101983942  DT.100010857  DT.100824241  DT.100824238  DT.121307595  DT.100824240  DT.91897020 
    DT.100708259  DT.121307559  DT.95267174  DT.121307561  DT.75169236  DT.91752923  DT.95251256 

    Selected AceView cDNA sequences (see all 286):

    AL043064 BG413377 BX395091 BX461273 AI805955 AL541156 CA425071 AL540615 
    BP373481 CD244089 BP346726 AI299782 BM557381 CA397688 CK823181 BX496261 
    NM_016607 NM_177948 BI771052 BQ576127 BX281685 BU626078 AI417034 CR597012 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ARMCX3 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b · 2c ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b · 5c · 5d · 5e · 5f · 5g
    SP1:                          -     -                 -     -                                                                     
    SP2:                          -                       -     -                                                                     
    SP3:                                -                 -     -                                                                     
    SP4:                                                  -     -                                                                     
    SP5:                          -     -     -           -     -                                                                     


    ECgene alternative splicing isoforms for ARMCX3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ARMCX3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    ARMCX3 Expression
    About this image


    ARMCX3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Testicular Interstitial Cells Testis Interstitium
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
     
     Neural Tube (Nervous System)
             Spinal Ventral Columns
     
     Thyroid (Endocrine System)
     
     Adrenal Gland (Endocrine System)
    ARMCX3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARMCX3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.592225
        Custom PCR Arrays for ARMCX3
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ARMCX3
    OriGene qSTAR qPCR primer pairs in human, mouse for ARMCX3
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARMCX3
    QuantiTect SYBR Green Assays in human, mouse, rat ARMCX3
    QuantiFast Probe-based Assays in human, mouse, rat ARMCX3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMCX3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for ARMCX3 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Armcx31 , 5 armadillo repeat containing, X-linked 31, 5 90.15(n)1
    96.57(a)1
      X (56.25 cM)5
    717031  NM_027870.31  NP_082146.21 
     1347565955 
    chicken
    (Gallus gallus)
    Aves --
    Uncharacterized protein
    39(a)
    1 → many
    1(12726364-12735694)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    40(a)
    1 → many
    5(95300984-95312074)
    zebrafish
    (Danio rerio)
    Actinopterygii ARMCX36
    armadillo repeat containing, X-linked 3
    30(a)
    1 → many
    25(19368321-19378457) ENSDARG00000062960


    ENSEMBL Gene Tree for ARMCX3 (if available)
    TreeFam Gene Tree for ARMCX3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ARMCX3 gene
    GPRASP22  ARMCX12  BHLHB92  ARMCX22  ARMCX52  GPRASP12  ARMCX62  ARMC102  
    7 SIMAP similar genes for ARMCX3 using alignment to 3 protein entries:     ARMX3_HUMAN (see all proteins):
    DKFZp686P06199    ARMCX4    ARMCX2    ARMC10    ARMCX6    ARMCX1
    ARMCX5

    Find genes that share paralogs with ARMCX3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ARMCX3 (see all 42)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1877506081,2
    --100843853(+) TCCCCA/GTAAGT 2 -- us2k10--------
    rs1931145001,2
    --100844152(+) CCTTAA/GCCAAC 3 -- us2k10--------
    rs1855235101,2
    C--100844576(+) TTGGTG/TGCAAG 3 -- us2k10--------
    rs1899970581,2
    --100844619(+) TGAGGA/GGATGT 3 -- us2k10--------
    rs27528901,2
    C,F,O,A,H--100844803(+) ATTCTT/CTATTT 3 -- us2k118Minor allele frequency- C:0.76NS EA NA WA CSA 1956
    rs1857717011,2
    --100848852(+) TGAATA/TTCACT 3 -- ut310--------
    rs69951,2
    C,F,O,A,H--100848999(+) TGTGTA/GTCATC 3 -- ut31 ese320Minor allele frequency- G:0.24MN NS EA NA WA 2330
    rs10586631,2
    A,H--100849040(+) AAAAAG/AAAGAA 3 -- ut31 trp34Minor allele frequency- A:0.00NS EA 418
    rs1901796811,2
    --100849095(+) AGATAA/CGAAAC 3 -- ut310--------
    rs1390032221,2
    --100849100(+) AGAAAC/TGTACA 3 -- ut310--------

    HapMap Linkage Disequilibrium report for ARMCX3 (100877787 - 100882833 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for ARMCX3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv522728CNV Gain19592680
    nsv524711CNV Gain19592680
    nsv207OTHER Inversion15895083
    nsv7452OTHER Inversion18451855

    Locus Specific Mutation Databases (LSDB): ARMCX3

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ARMCX3
    DNA2.0 Custom Variant and Variant Library Synthesis for ARMCX3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 300364    OMIM disorders: --


    Find genes that share disorders with ARMCX3           About GenesLikeMe


    Export disorders for ARMCX3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ARMCX3 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with ARMCX3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas. (PubMed id 11162520)1, 2, 3 Kurochkin I.V.... Nomura H. (Biochem. Biophys. Res. Commun. 2001)
    2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    3. The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2. (PubMed id 22569362)1, 3 LA^pez-DomAcnech G....Soriano E. (Nat Commun 2012)
    4. The armadillo repeat-containing protein, ARMCX3, physically and functionally interacts with the developmental regulatory factor Sox10. (PubMed id 19304657)1, 3 Mou Z....Gardner P.D. (J. Biol. Chem. 2009)
    5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    6. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    7. Mammalian BEX, WEX and GASP genes: coding and non-coding chimaerism sustained by gene conversion events. (PubMed id 16221301)1, 3 Winter E.E. and Ponting C.P. (BMC Evol. Biol. 2005)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    10. The non-canonical Wnt/PKC pathway regulates mitochondrial dynamics through degradation of the arm-like domain-containing protein Alex3. (PubMed id 23844091)1 Serrat R....Soriano E. (PLoS ONE 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 51566 HGNC: 24065 AceView: ARMCX3 Ensembl:ENSG00000102401 euGenes: HUgn51566
    ECgene: ARMCX3 H-InvDB: ARMCX3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ARMCX3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ARMCX3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ARMCX3 gene:
    Search GeneIP for patents involving ARMCX3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for ARMCX3   OriGene RNAi products in human, mouse, rat for ARMCX3  
     OriGene qPCR primer pairs and template standards for ARMCX3   OriGene Protein Over-expression Lysate for ARMCX3  
     OriGene MassSpec something-or-other for ARMCX3   OriGene clones in human, mouse for ARMCX3  
     OriGene qSTAR qPCR primer pairs in human, mouse for ARMCX3   OriGene Purified Protein for ARMCX3  
     OriGene ORF clones in mouse, rat for ARMCX3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ARMCX3   OriGene Custom Protein Services for ARMCX3  

     
     
     Block miRNA regulation of human, mouse, rat ARMCX3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ARMCX3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARMCX3 Predesigned siRNA for gene silencing in human, mouse, rat ARMCX3
     QuantiFast Probe-based Assays in human, mouse, rat ARMCX3 QuantiTect SYBR Green Assays in human, mouse, rat ARMCX3
     Custom PCR Arrays for ARMCX3 Search Chromatin IP Primers for ARMCX3
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARMCX3  Search GeneGlobe Interaction Network for ARMCX3
     Regulatory tfbs in ARMCX3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ARMCX3 GenScript cDNA clones with any tag delivered in your preferred vector for ARMCX3
     GenScript Custom Assay Services for ARMCX3 GenScript Custom overexpressing Cell Line Services for ARMCX3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ARMCX3 (ARMX3)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ARMCX3 antibodies
     ARMCX3 proteins
     ARMCX3 lysates
     Antibodies for ARMCX3
     See all of Abcam's Antibodies, Kits and Proteins for ARMCX3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ARMCX3
     Antibodies for ARMCX3
     ELISAs for ARMCX3
     CLIAs for ARMCX3



     Browse ESI BIO Cell Lines and PureStem Progenitors for ARMCX3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMCX3
     SwitchGear 3'UTR luciferase reporter plasmids for ARMCX3
     SwitchGear Promoter luciferase reporter plasmids for ARMCX3
     Search ThermoFisher Antibodies for ARMCX3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMCX3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARMCX3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ARMCX3
     LSBio Antibodies in human, mouse, rat for ARMCX3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for ARMCX3
      Search eBioscience for proteins for ARMCX3
      Search eBioscience for elisas for ARMCX3
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ARMCX3 gene at Home site.
    Version: 3.12.224 13 Oct 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4