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Aliases for ARMC9 Gene

Aliases for ARMC9 Gene

  • Armadillo Repeat Containing 9 2 3 5
  • Melanoma/Melanocyte-Specific Tumor Antigen KU-MEL-1 3 4
  • NS21 3 4
  • Melanoma/Melanocyte Specific Protein KU-MEL-1 3
  • Armadillo/Beta-Catenin-Like Repeats 3
  • KU-MEL-1 3
  • KIAA1868 4
  • ARM 3

External Ids for ARMC9 Gene

Previous GeneCards Identifiers for ARMC9 Gene

  • GC02P231889
  • GC02P231771
  • GC02P232064
  • GC02P223905

Summaries for ARMC9 Gene

GeneCards Summary for ARMC9 Gene

ARMC9 (Armadillo Repeat Containing 9) is a Protein Coding gene. GO annotations related to this gene include binding.

Gene Wiki entry for ARMC9 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMC9 Gene

Genomics for ARMC9 Gene

Regulatory Elements for ARMC9 Gene

Promoters for ARMC9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ARMC9 on UCSC Golden Path with GeneCards custom track

Genomic Location for ARMC9 Gene

Chromosome:
2
Start:
231,198,546 bp from pter
End:
231,394,991 bp from pter
Size:
196,446 bases
Orientation:
Plus strand

Genomic View for ARMC9 Gene

Genes around ARMC9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARMC9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARMC9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMC9 Gene

Proteins for ARMC9 Gene

  • Protein details for ARMC9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q7Z3E5-ARMC9_HUMAN
    Recommended name:
    LisH domain-containing protein ARMC9
    Protein Accession:
    Q7Z3E5
    Secondary Accessions:
    • Q53TI3
    • Q6P162
    • Q7L594
    • Q86WG2
    • Q96JF9
    • Q9H9R8

    Protein attributes for ARMC9 Gene

    Size:
    817 amino acids
    Molecular mass:
    91762 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAB14153.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for ARMC9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARMC9 Gene

Proteomics data for ARMC9 Gene at MOPED

Post-translational modifications for ARMC9 Gene

  • Ubiquitination at Lys 441
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for ARMC9 Gene

Domains & Families for ARMC9 Gene

Gene Families for ARMC9 Gene

Protein Domains for ARMC9 Gene

Suggested Antigen Peptide Sequences for ARMC9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q7Z3E5

UniProtKB/Swiss-Prot:

ARMC9_HUMAN :
  • Contains 1 LisH domain.
Domain:
  • Contains 1 LisH domain.
genes like me logo Genes that share domains with ARMC9: view

Function for ARMC9 Gene

Phenotypes for ARMC9 Gene

GenomeRNAi human phenotypes for ARMC9:
genes like me logo Genes that share phenotypes with ARMC9: view

Animal Model Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARMC9 Gene

Localization for ARMC9 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARMC9 Gene COMPARTMENTS Subcellular localization image for ARMC9 gene
Compartment Confidence
extracellular 5
cytoskeleton 3
cytosol 3
nucleus 3
endoplasmic reticulum 1
lysosome 1
vacuole 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARMC9 Gene

Pathways & Interactions for ARMC9 Gene

SuperPathways for ARMC9 Gene

No Data Available

Gene Ontology (GO) - Biological Process for ARMC9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARMC9 Gene

Drugs & Compounds for ARMC9 Gene

No Compound Related Data Available

Transcripts for ARMC9 Gene

Unigene Clusters for ARMC9 Gene

Armadillo repeat containing 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARMC9 Gene

No ASD Table

Relevant External Links for ARMC9 Gene

GeneLoc Exon Structure for
ARMC9
ECgene alternative splicing isoforms for
ARMC9

Expression for ARMC9 Gene

mRNA expression in normal human tissues for ARMC9 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ARMC9 Gene

This gene is overexpressed in Esophagus - Muscularis (x4.8).

Protein differential expression in normal tissues from HIPED for ARMC9 Gene

This gene is overexpressed in Bone (65.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for ARMC9 Gene



SOURCE GeneReport for Unigene cluster for ARMC9 Gene Hs.471610

mRNA Expression by UniProt/SwissProt for ARMC9 Gene

Q7Z3E5-ARMC9_HUMAN
Tissue specificity: Strongly expressed in most melanomas and melanocytes. Weakly expressed in the testis.
genes like me logo Genes that share expression patterns with ARMC9: view

Primer Products

In Situ Assay Products

No data available for Protein tissue co-expression partners for ARMC9 Gene

Orthologs for ARMC9 Gene

This gene was present in the common ancestor of animals.

Orthologs for ARMC9 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ARMC9 35
  • 89.51 (n)
  • 90.96 (a)
ARMC9 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARMC9 35
  • 87.04 (n)
  • 85.19 (a)
ARMC9 36
  • 75 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Armc9 35
  • 84.4 (n)
  • 85.91 (a)
Armc9 16
Armc9 36
  • 75 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ARMC9 35
  • 99.19 (n)
  • 98.9 (a)
ARMC9 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Armc9 35
  • 83.97 (n)
  • 85.25 (a)
oppossum
(Monodelphis domestica)
Mammalia ARMC9 36
  • 70 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 69 (a)
OneToMany
-- 36
  • 82 (a)
OneToMany
-- 36
  • 78 (a)
OneToMany
chicken
(Gallus gallus)
Aves ARMC9 35
  • 71.81 (n)
  • 72.64 (a)
ARMC9 36
  • 65 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARMC9 36
  • 64 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia armc9 35
  • 63.02 (n)
  • 59.58 (a)
zebrafish
(Danio rerio)
Actinopterygii LOC100334308 35
  • 62.3 (n)
  • 59.52 (a)
armc9 36
  • 50 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F59G1.4 36
  • 17 (a)
OneToOne
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.13954 35
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 53 (a)
OneToOne
Species with no ortholog for ARMC9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ARMC9 Gene

ENSEMBL:
Gene Tree for ARMC9 (if available)
TreeFam:
Gene Tree for ARMC9 (if available)

Paralogs for ARMC9 Gene

No data available for Paralogs for ARMC9 Gene

Variants for ARMC9 Gene

Sequence variations from dbSNP and Humsavar for ARMC9 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs11558175 - 231,214,975(+) TCTAT(C/T)TTTTG nc-transcript-variant, reference, missense
rs16827883 - 231,235,227(+) AGAAA(C/T)CTTGC nc-transcript-variant, reference, missense
rs3752780 - 231,235,266(+) TGAAC(A/G)TAGGT nc-transcript-variant, reference, missense
rs1626450 - 231,222,761(+) AGTTG(A/G)TAAAG nc-transcript-variant, reference, missense
VAR_069411 -

Structural Variations from Database of Genomic Variants (DGV) for ARMC9 Gene

Variant ID Type Subtype PubMed ID
esv2721611 CNV Deletion 23290073
esv2721612 CNV Deletion 23290073
esv2277694 CNV Deletion 18987734
nsv834566 CNV Loss 17160897
nsv518307 CNV Loss 19592680

Variation tolerance for ARMC9 Gene

Residual Variation Intolerance Score: 49.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.73; 57.66% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ARMC9 Gene

HapMap Linkage Disequilibrium report
ARMC9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARMC9 Gene

Disorders for ARMC9 Gene

Relevant External Links for ARMC9

Genetic Association Database (GAD)
ARMC9
Human Genome Epidemiology (HuGE) Navigator
ARMC9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ARMC9

No disorders were found for ARMC9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARMC9 Gene

Publications for ARMC9 Gene

  1. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11347906) Nagase T. … Ohara O. (DNA Res. 2001) 2 3 4 67
  2. Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens. (PMID: 24962563) Rubicz R. … GAPring H.H. (Genet. Epidemiol. 2014) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans. (PMID: 23400010) Del-Aguila J.L. … Boerwinkle E. (Pharmacogenomics J. 2013) 3
  5. Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk. (PMID: 23955597) Chubb D. … Goldschmidt H. (Nat. Genet. 2013) 3

Products for ARMC9 Gene

Sources for ARMC9 Gene

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