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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARMC8 Gene

protein-coding   GIFtS: 47
GCID: GC03P137906

Armadillo Repeat Containing 8

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Armadillo Repeat Containing 81 2     HSPC0562
GID Complex Subunit 51     VID282
VID28 Homolog (S. Cerevisiae)1     Armadillo Repeat-Containing Protein 82
GID52     GID Complex Subunit 5, VID28 Homolog2

External Ids:    HGNC: 249991   Entrez Gene: 258522   Ensembl: ENSG000001140987   UniProtKB: Q8IUR73   

Export aliases for ARMC8 gene to outside databases

Previous GC identifers: GC03P139389 GC03P135282


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for ARMC8 Gene: 
ARMC8 (armadillo repeat containing 8) is a protein-coding gene. Diseases associated with ARMC8 include lissencephaly.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_005612.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARMC8 gene promoter:
         RFX1   C/EBPbeta   POU3F1   Cdc5   AREB6   FAC1   STAT3   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARMC8 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARMC8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARMC8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.3   Ensembl cytogenetic band:  3q22.3   HGNC cytogenetic band: 3q22

ARMC8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARMC8 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P137906:  view genomic region     (about GC identifiers)

Start:
137,906,109 bp from pter      End:
138,017,231 bp from pter
Size:
111,123 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARMC8_HUMAN, Q8IUR7 (See protein sequence)
Recommended Name: Armadillo repeat-containing protein 8  
Size: 673 amino acids; 75509 Da
Sequence caution: Sequence=BAA91861.1; Type=Frameshift; Positions=468; Sequence=BAA91959.1; Type=Miscellaneous
discrepancy; Note=Intron retention; Sequence=CAB46423.1; Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: A8K0L2 B7Z441 B7Z453 D3DNE6 F5GWK4 Q6PIL2 Q96D19 Q96HZ5 Q9NV02 Q9NV94
Q9Y4R9
Alternative splicing: 6 isoforms:  Q8IUR7-1   Q8IUR7-2   Q8IUR7-3   Q8IUR7-6   Q8IUR7-7   Q8IUR7-8   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARMC8: NX_Q8IUR7

Explore proteomics data for ARMC8 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IUR7

  • ARMC8 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARMC8 Protein Expression
    REFSEQ proteins (6 alternative transcripts): 
    NP_001253970.1  NP_001253971.1  NP_001269271.1  NP_054873.2  NP_056211.2  NP_998819.1  

    ENSEMBL proteins: 
     ENSP00000420333   ENSP00000419413   ENSP00000417304   ENSP00000418074   ENSP00000417699  
     ENSP00000351221   ENSP00000418412   ENSP00000420706   ENSP00000417049   ENSP00000420440  
     ENSP00000418405   ENSP00000420719   ENSP00000417403   ENSP00000418457   ENSP00000419888  
     ENSP00000419473   ENSP00000417457   ENSP00000441592   ENSP00000376778  

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    Cloud-Clone Corp. CLIAs for ARMC8


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARMC: Armadillo repeat containing

    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR000225 Armadillo
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q8IUR7

    ProtoNet protein and cluster: Q8IUR7

    UniProtKB/Swiss-Prot: ARMC8_HUMAN, Q8IUR7
    Similarity: Contains 14 ARM repeats


    ARMC8 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
         
    ARMC8 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Armc8):
     no phenotypic analysis 

    ARMC8 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARMC8 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ARMC8

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARMC8 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARMC8 

    miRNA
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    8/118 QIAGEN miScript miRNA Assays for microRNAs that regulate ARMC8 (see all 118):
    hsa-miR-411* hsa-miR-361-5p hsa-miR-520f hsa-miR-3146 hsa-miR-300 hsa-miR-199a-3p hsa-miR-146a hsa-miR-4272
    SwitchGear 3'UTR luciferase reporter plasmidARMC8 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC8


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARMC8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    5/9 Interacting proteins for ARMC8 (Q8IUR72, 3 ENSP000003512214) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNNT1P138052, 3, ENSP000002919014MINT-8274808 I2D: score=2 STRING: ENSP00000291901
    CHMP243863, ENSP000003503864I2D: score=1 STRING: ENSP00000350386
    RAE1P784063, ENSP000003602864I2D: score=1 STRING: ENSP00000360286
    RNPS1Q152873, ENSP000003158594I2D: score=1 STRING: ENSP00000315859
    DVL2O146413I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARMC8

    Search CenterWatch for drugs/clinical trials and news about ARMC8

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARMC8 gene (6 alternative transcripts): 
    NM_001267041.2  NM_001267042.2  NM_001282342.1  NM_014154.4  NM_015396.5  NM_213654.3  

    Unigene Cluster for ARMC8:

    Armadillo repeat containing 8
    Hs.744868  [show with all ESTs]
    Unigene Representative Sequence: NM_015396
    18/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):
    ENST00000481646 ENST00000469044(uc003esa.1 uc011bmf.1 uc011bmg.1 uc011bmh.1 uc003esb.1 uc003esc.1)
    ENST00000491704 ENST00000461600 ENST00000466749 ENST00000358441(uc003erw.3 uc003erx.3 uc003ery.3)
    ENST00000489213 ENST00000461822 ENST00000485396 ENST00000471453 ENST00000470821
    ENST00000471709 ENST00000463485 ENST00000468560 ENST00000470842 ENST00000470549
    ENST00000469860 ENST00000460495
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARMC8
    8/118 QIAGEN miScript miRNA Assays for microRNAs that regulate ARMC8 (see all 118):
    hsa-miR-411* hsa-miR-361-5p hsa-miR-520f hsa-miR-3146 hsa-miR-300 hsa-miR-199a-3p hsa-miR-146a hsa-miR-4272
    SwitchGear 3'UTR luciferase reporter plasmidARMC8 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ARMC8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARMC8
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC8
    Sirion Biotech Customized lentivirus for stable overexpression of ARMC8 
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    Primer
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    OriGene qPCR primer pairs and template standards for ARMC8
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARMC8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARMC8

    Additional mRNA sequence: 

    AF109184.1 AF161541.1 AK001721.1 AK098500.1 AK289577.1 AK296757.1 AK296837.1 AK299229.1 
    AK299769.1 AK304558.1 AK315932.1 BC013424.1 BC032661.1 BC041699.1 NR_049770.1 

    24/25 DOTS entries (see all 25):

    DT.100779805  DT.448578  DT.100779806  DT.443539  DT.91761400  DT.100779810  DT.120863671  DT.91761423 
    DT.120863641  DT.95132015  DT.100026342  DT.100779807  DT.95132026  DT.95132013  DT.95132024  DT.120863726 
    DT.91761413  DT.120863678  DT.97781751  DT.100647754  DT.120863657  DT.65284948  DT.75148987  DT.95117274 

    24/282 AceView cDNA sequences (see all 282):

    AW779893 AA702776 AA723477 AL602779 BM833107 BQ937870 BG699271 CR618018 
    AI079289 AL096748 BX497886 AA568700 AI368977 AI888413 BX364149 AI913397 
    AW190410 AL522785 BP378716 CD679045 AA621112 BM824733 BG564432 NM_015396 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ARMC8 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d ^ 14 ^
    SP1:                                -     -     -           -     -     -                             -                                   -     -     -         
    SP2:                                                                                                  -                                                         
    SP3:                                -     -     -                                                     -                                                         
    SP4:                                -                                                                                                                           
    SP5:                                -     -                                                                                                                     

    ExUns: 15 ^ 16
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for ARMC8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARMC8 expression in normal human tissues (normalized intensities)      ARMC8 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCAGAATG
    ARMC8 Expression
    About this image


    ARMC8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Blood (Hematopoietic System)    fully expand to see all 5 entries
             bone marrow cd34+   
     
     Umbilical Cord (Extraembryonic Tissues)    fully expand to see all 2 entries
             stem cells (umbilical cord cd34+)   
     
     Ovary (Reproductive System)
             Ovarian Somatic Cells Ovigerous Cord
     
     Endothelium (Cardiovascular System)
             blood vessel   
     
     Skeletal Muscle (Muscoskeletal System)
             deltoid muscle   

    See ARMC8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARMC8

    SOURCE GeneReport for Unigene cluster: Hs.744868
        SABiosciences Custom PCR Arrays for ARMC8
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ARMC8 gene from 8/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Armc81 , 5 armadillo repeat containing 81, 5 92.96(n)1
    98.78(a)1
      9 (51.74 cM)5
    741251  NM_028768.31  NP_083044.21 
     994783915 
    chicken
    (Gallus gallus)
    Aves ARMC81 armadillo repeat containing 8 84.5(n)
    94.83(a)
      424731  NM_001252163.1  NP_001239092.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARMC86
    armadillo repeat containing 8
    86(a)
    1 ↔ 1
    3(34978312-35136808)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.37352 Xenopus laevis transcribed sequences 79.7(n)    BX844832.1 
    zebrafish
    (Danio rerio)
    Actinopterygii armc81 armadillo repeat containing 8 74.06(n)
    86.63(a)
      571528  NM_001079683.1  NP_001073151.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0066261 AGAP006626-PA 50.34(n)
    43.86(a)
      1277212  XM_316656.4  XP_316656.4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G513501 armadillo/beta-catenin-like repeats-containing protein 40.88(n)
    28.19(a)
      841558  NM_104013.2  NP_175546.1 
    rice
    (Oryza sativa)
    Liliopsida Os11g06389001 hypothetical protein 38.62(n)
    25(a)
      4350991  NM_001074872.1  NP_001068340.1 


    ENSEMBL Gene Tree for ARMC8 (if available)
    TreeFam Gene Tree for ARMC8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARMC8 gene

    ARMC8 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ARMC8
    PGOHUM00000236034


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1292 SNPs in ARMC8 are shown (see all 1292)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2006716721,2
    C--137904145(+) GCAGA-/CTCTGCT 6 -- us2k10--------
    rs1378873071,2
    C--137904159(+) TTTGTA/GTCAGG 6 -- us2k10--------
    rs1406908011,2
    --137904162(+) GTATCA/TGGTTA 6 -- us2k10--------
    rs1459061371,2
    C--137904340(+) TAAACA/GGTGGC 6 -- us2k10--------
    rs1679081,2
    C,F,A,H--137904492(+) TTCGTT/ACAACA 6 -- us2k1 tfbs318Minor allele frequency- A:0.11NS EA NA WA CSA 1223
    rs1496231771,2
    --137904754(+) CTCTAC/TATACT 6 -- us2k10--------
    rs3293871,2
    C,F,A,H--137904853(+) TAGTTG/AATGTG 6 -- us2k1 tfbs317Minor allele frequency- A:0.37NS EA NA WA CSA 781
    rs1442747751,2
    --137904899(+) TTTCAC/TAGAGT 6 -- us2k10--------
    rs98725041,2
    C,F,H--137904900(+) TTCACA/GGAGTA 6 -- us2k14Minor allele frequency- G:0.00NS EA 416
    rs1887926601,2
    --137904906(+) GAGTAC/TTATGG 6 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARMC8 (137906109 - 138017231 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ARMC8:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4030CNV Insertion18451855
    nsv822264CNV Loss20364138
    nsv822263CNV Loss20364138
    nsv877537CNV Gain21882294
    nsv877536CNV Gain21882294
    nsv428422CNV Gain+Loss18775914
    dgv1511e1CNV Complex17122850
    dgv1512e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ARMC8:    About MalaCards
    lissencephaly    

    1 disease from the University of Copenhagen DISEASES database for ARMC8:
    Lissencephaly

    ARMC8 for disorders           About GeneDecksing


    Export disorders for ARMC8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARMC8 gene, integrated from 9 sources (see all 18):
    (articles sorted by number of sources associating them with ARMC8)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (2000)
    3. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (2013)
    4. NOTCH1 nuclear interactome reveals key regulators of i ts transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (2012)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
    7. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    8. Armadillo Repeat Containing 8alpha Binds to HRS and P romotes HRS Interaction with Ubiquitinated Proteins. (PubMed id 20224683)1 Tomaru K....Ishigatsubo Y. (2010)
    9. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    10. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25852 HGNC: 24999 AceView: ARMC8 Ensembl:ENSG00000114098 euGenes: HUgn25852
    ECgene: ARMC8 H-InvDB: ARMC8

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARMC8 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ARMC8 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARMC8 gene:
    Search GeneIP for patents involving ARMC8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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