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ARMC8 Gene

protein-coding   GIFtS: 45
GCID: GC03P137906

Armadillo Repeat Containing 8

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Armadillo Repeat Containing 81 2     HSPC0562
GID Complex Subunit 51     VID282
VID28 Homolog (S. Cerevisiae)1     Armadillo Repeat-Containing Protein 82
GID52     GID Complex Subunit 5, VID28 Homolog2

External Ids:    HGNC: 249991   Entrez Gene: 258522   Ensembl: ENSG000001140987   UniProtKB: Q8IUR73   

Export aliases for ARMC8 gene to outside databases

Previous GC identifers: GC03P139389 GC03P135282


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ARMC8 Gene:
ARMC8 (armadillo repeat containing 8) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the ARMC8 gene promoter:
         RFX1   C/EBPbeta   POU3F1   Cdc5   AREB6   FAC1   STAT3   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARMC8 promoter sequence
   Search Chromatin IP Primers for ARMC8

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARMC8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q22.3   Ensembl cytogenetic band:  3q22.3   HGNC cytogenetic band: 3q22

ARMC8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARMC8 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P137906:  view genomic region     (about GC identifiers)

Start:
137,906,109 bp from pter      End:
138,017,231 bp from pter
Size:
111,123 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ARMC8_HUMAN, Q8IUR7 (See protein sequence)
Recommended Name: Armadillo repeat-containing protein 8  
Size: 673 amino acids; 75509 Da
Sequence caution: Sequence=BAA91861.1; Type=Frameshift; Positions=468; Sequence=BAA91959.1; Type=Miscellaneous
discrepancy; Note=Intron retention; Sequence=CAB46423.1; Type=Miscellaneous discrepancy; Note=Intron retention;
Secondary accessions: A8K0L2 B7Z441 B7Z453 D3DNE6 F5GWK4 Q6PIL2 Q96D19 Q96HZ5 Q9NV02 Q9NV94
Q9Y4R9
Alternative splicing: 6 isoforms:  Q8IUR7-1   Q8IUR7-2   Q8IUR7-3   Q8IUR7-6   Q8IUR7-7   Q8IUR7-8   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARMC8: NX_Q8IUR7

Explore proteomics data for ARMC8 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ARMC8 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (6 alternative transcripts): 
    NP_001253970.1  NP_001253971.1  NP_001269271.1  NP_054873.2  NP_056211.2  NP_998819.1  

    ENSEMBL proteins: 
     ENSP00000420333   ENSP00000419413   ENSP00000417304   ENSP00000418074   ENSP00000417699  
     ENSP00000351221   ENSP00000418412   ENSP00000420706   ENSP00000417049   ENSP00000420440  
     ENSP00000418405   ENSP00000420719   ENSP00000417403   ENSP00000418457   ENSP00000419888  
     ENSP00000419473   ENSP00000417457   ENSP00000441592   ENSP00000376778  

    ARMC8 Human Recombinant Protein Products:

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    Novus Biologicals ARMC8 Proteins
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    Cloud-Clone Corp. Proteins for ARMC8

     
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    antibodies-online proteins for ARMC8 (6 products) 

     
    antibodies-online peptides for ARMC8

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    antibodies-online antibodies for ARMC8 (19 products) 

    ARMC8 Assay Products:

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    Cloud-Clone Corp. ELISAs for ARMC8
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    antibodies-online kits for ARMC8 (18 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ARMC: Armadillo repeat containing

    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR000225 Armadillo
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q8IUR7

    ProtoNet protein and cluster: Q8IUR7

    UniProtKB/Swiss-Prot: ARMC8_HUMAN, Q8IUR7
    Similarity: Contains 14 ARM repeats


    Find genes that share domains with ARMC8           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
         
    Find genes that share ontologies with ARMC8           About GenesLikeMe


    Phenotypes:
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Armc8):
     no phenotypic analysis 

    Find genes that share phenotypes with ARMC8           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ARMC8

    miRNA
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    miRTarBase miRNAs that target ARMC8:
    hsa-let-7a-3p (MIRT038998), hsa-let-7c-5p (MIRT051825), hsa-mir-26b-5p (MIRT030148), hsa-let-7f-5p (MIRT051358)

    Block miRNA regulation of human, mouse, rat ARMC8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARMC8 (see all 118):
    hsa-miR-411* hsa-miR-361-5p hsa-miR-520f hsa-miR-3146 hsa-miR-300 hsa-miR-199a-3p hsa-miR-146a hsa-miR-4272
    SwitchGear 3'UTR luciferase reporter plasmidARMC8 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Predesigned siRNA for gene silencing in human, mouse, rat ARMC8

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 3): ARMC8 (NM_014154)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMC8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC8

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC8


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARMC8
    Interactions:

        Search GeneGlobe Interaction Network for ARMC8

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    Selected Interacting proteins for ARMC8 (Q8IUR72, 3 ENSP000003512214) via UniProtKB, MINT, STRING, and/or I2D (see all 24)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TNNT1P138052, 3, ENSP000002919014MINT-8274808 I2D: score=2 STRING: ENSP00000291901
    CHMP243863, ENSP000003503864I2D: score=1 STRING: ENSP00000350386
    RAE1P784063, ENSP000003602864I2D: score=1 STRING: ENSP00000360286
    RNPS1Q152873, ENSP000003158594I2D: score=1 STRING: ENSP00000315859
    DVL2O146413I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARMC8



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ARMC8 gene (6 alternative transcripts): 
    NM_001267041.2  NM_001267042.2  NM_001282342.1  NM_014154.4  NM_015396.5  NM_213654.3  

    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24):
    ENST00000481646 ENST00000469044(uc003esa.1 uc011bmf.1 uc011bmg.1 uc011bmh.1 uc003esb.1 uc003esc.1)
    ENST00000491704 ENST00000461600 ENST00000466749 ENST00000358441(uc003erw.3 uc003erx.3 uc003ery.3)
    ENST00000489213 ENST00000461822 ENST00000485396 ENST00000471453 ENST00000470821
    ENST00000471709 ENST00000463485 ENST00000468560 ENST00000470842 ENST00000470549
    ENST00000469860 ENST00000460495
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ARMC8 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ARMC8 (see all 118):
    hsa-miR-411* hsa-miR-361-5p hsa-miR-520f hsa-miR-3146 hsa-miR-300 hsa-miR-199a-3p hsa-miR-146a hsa-miR-4272
    SwitchGear 3'UTR luciferase reporter plasmidARMC8 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ARMC8
    Predesigned siRNA for gene silencing in human, mouse, rat ARMC8
    Clone
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    OriGene clones in human, mouse for ARMC8 (see all 22)
    OriGene ORF clones in mouse, rat for ARMC8
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): ARMC8 (NM_014154)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMC8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC8
    Primer
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    OriGene qPCR primer pairs and template standards for ARMC8
    OriGene qSTAR qPCR primer pairs in human, mouse for ARMC8
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ARMC8
      QuantiTect SYBR Green Assays in human, mouse, rat ARMC8
      QuantiFast Probe-based Assays in human, mouse, rat ARMC8

    Selected AceView cDNA sequences (see all 282):

    AU136143 AA969157 AA732759 BC013424 CD679045 AA363446 CB157887 AI079289 
    AW779894 BQ937870 BU619663 AA626078 BM754596 AA251677 BG699271 AA621112 
    AA315197 NM_213654 AI888413 BG218500 BG564432 CA419114 BQ896831 CD368681 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ARMC8 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b · 13c · 13d ^ 14 ^
    SP1:                                -     -     -           -     -     -                             -                                   -     -     -         
    SP2:                                                                                                  -                                                         
    SP3:                                -     -     -                                                     -                                                         
    SP4:                                -                                                                                                                           
    SP5:                                -     -                                                                                                                     

    ExUns: 15 ^ 16
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for ARMC8

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARMC8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGCCAGAATG
    ARMC8 Expression
    About this image


    ARMC8 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Ovary (Reproductive System)
             Ovarian Somatic Cells Ovigerous Cord
    ARMC8 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARMC8 Protein Expression
        Custom PCR Arrays for ARMC8
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC8

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ARMC8 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Armc81 , 5 armadillo repeat containing 81, 5 92.96(n)1
    98.78(a)1
      9 (51.74 cM)5
    741251  NM_028768.31  NP_083044.21 
     994783915 
    chicken
    (Gallus gallus)
    Aves ARMC81 armadillo repeat containing 8 84.5(n)
    94.83(a)
      424731  NM_001252163.1  NP_001239092.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARMC86
    armadillo repeat containing 8
    86(a)
    1 ↔ 1
    3(34978312-35136808)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.37352 Xenopus laevis transcribed sequences 79.7(n)    BX844832.1 
    zebrafish
    (Danio rerio)
    Actinopterygii armc81 armadillo repeat containing 8 74.06(n)
    86.63(a)
      571528  NM_001079683.1  NP_001073151.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0066261 AgaP_AGAP006626 50.34(n)
    43.86(a)
      1277212  XM_316656.4  XP_316656.4 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT1G513501 AT1G51350 42.36(n)
    29.64(a)
      841558  NM_104013.2  NP_175546.1 
    rice
    (Oryza sativa)
    Liliopsida Os11g06389001 Os11g0638900   --   4350991  NM_001074872.1  NP_001068340.1 


    ENSEMBL Gene Tree for ARMC8 (if available)
    TreeFam Gene Tree for ARMC8 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARMC8 gene

    Find genes that share paralogs with ARMC8           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ARMC8
    PGOHUM00000236034


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARMC8 (see all 1292)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2006716721,2
    C--137904145(+) GCAGA-/CTCTGCT 6 -- us2k10--------
    rs1378873071,2
    C--137904159(+) TTTGTA/GTCAGG 6 -- us2k10--------
    rs1406908011,2
    --137904162(+) GTATCA/TGGTTA 6 -- us2k10--------
    rs1459061371,2
    C--137904340(+) TAAACA/GGTGGC 6 -- us2k10--------
    rs1679081,2
    C,F,A,H--137904492(+) TTCGTT/ACAACA 6 -- us2k1 tfbs318Minor allele frequency- A:0.11NS EA NA WA CSA 1223
    rs1496231771,2
    --137904754(+) CTCTAC/TATACT 6 -- us2k10--------
    rs3293871,2
    C,F,A,H--137904853(+) TAGTTG/AATGTG 6 -- us2k1 tfbs317Minor allele frequency- A:0.37NS EA NA WA CSA 781
    rs1442747751,2
    --137904899(+) TTTCAC/TAGAGT 6 -- us2k10--------
    rs98725041,2
    C,F,H--137904900(+) TTCACA/GGAGTA 6 -- us2k14Minor allele frequency- G:0.00NS EA 416
    rs1887926601,2
    --137904906(+) GAGTAC/TTATGG 6 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARMC8 (137906109 - 138017231 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for ARMC8:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv4030CNV Insertion18451855
    nsv822264CNV Loss20364138
    nsv822263CNV Loss20364138
    nsv877537CNV Gain21882294
    nsv877536CNV Gain21882294
    nsv428422CNV Gain+Loss18775914
    dgv1511e1CNV Complex17122850
    dgv1512e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ARMC8
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease from the University of Copenhagen DISEASES database for ARMC8:
    Lissencephaly

    Find genes that share disorders with ARMC8           About GenesLikeMe


    Export disorders for ARMC8 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARMC8 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with ARMC8)
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    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    3. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    4. Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics. (PubMed id 23956138)1 Foerster S....Ritter C.A. (Proteomics 2013)
    5. NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function. (PubMed id 23022380)1 Yatim A....Benkirane M. (Mol. Cell 2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. A directed protein interaction network for investigating intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (Sci Signal 2011)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Armadillo Repeat Containing 8alpha Binds to HRS and Promotes HRS Interaction with Ubiquitinated Proteins. (PubMed id 20224683)1 Tomaru K....Ishigatsubo Y. (Open Biochem J 2010)
    10. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25852 HGNC: 24999 AceView: ARMC8 Ensembl:ENSG00000114098 euGenes: HUgn25852
    ECgene: ARMC8 H-InvDB: ARMC8

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ARMC8 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ARMC8 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ARMC8 gene:
    Search GeneIP for patents involving ARMC8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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