Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARMC6 Gene

protein-coding   GIFtS: 48
GCID: GC19P019144

Armadillo Repeat Containing 6

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Armadillo Repeat Containing 61 2
R30923_12
Armadillo Repeat-Containing Protein 62

External Ids:    HGNC: 250491   Entrez Gene: 934362   Ensembl: ENSG000001056767   UniProtKB: Q6NXE63   

Export aliases for ARMC6 gene to outside databases

Previous GC identifers: GC19P019006 GC19P018708


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARMC6 Gene:
The function of this gene's protein product has not been determined. A related protein in mouse suggests that this
protein has a conserved function. Two transcript variants encoding different isoforms have been found for this
gene. (provided by RefSeq, Nov 2010)

GeneCards Summary for ARMC6 Gene: 
ARMC6 (armadillo repeat containing 6) is a protein-coding gene. Diseases associated with ARMC6 include pancreatic cancer, and pancreatitis.

Gene Wiki entry for ARMC6 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NT_011295.11  NC_018930.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARMC6 gene promoter:
         NF-1/L   NF-1   Pax-5   GCNF   IRF-1   Gfi-1   YY1   C/EBPalpha   GCNF-1   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARMC6 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARMC6

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARMC6


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.11   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13

ARMC6 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARMC6 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P019144:  view genomic region     (about GC identifiers)

Start:
19,144,384 bp from pter      End:
19,170,563 bp from pter
Size:
26,180 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARMC6_HUMAN, Q6NXE6 (See protein sequence)
Recommended Name: Armadillo repeat-containing protein 6  
Size: 501 amino acids; 54142 Da
Caution: It is uncertain whether Met-1 or Met-26 is the initiator
Sequence caution: Sequence=AAD03162.1; Type=Erroneous gene model prediction; Sequence=AAH67125.1; Type=Erroneous
initiation; Note=Translation N-terminally extended;
Secondary accessions: B4DI98 O94999 Q9BTH5
Alternative splicing: 2 isoforms:  Q6NXE6-1   Q6NXE6-2   (Gene prediction based on EST data)

Explore the universe of human proteins at neXtProt for ARMC6: NX_Q6NXE6

Explore proteomics data for ARMC6 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6NXE6

  • ARMC6 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARMC6 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001186125.1  NP_219483.1  

    ENSEMBL proteins: 
     ENSP00000376147   ENSP00000444156   ENSP00000441948   ENSP00000442263   ENSP00000446209  
     ENSP00000269932   ENSP00000444341   ENSP00000439269   ENSP00000439038   ENSP00000446037  
     ENSP00000441420   ENSP00000439003   ENSP00000444317   ENSP00000437580   ENSP00000438369  
     ENSP00000376148   ENSP00000444916   ENSP00000446234   ENSP00000444265   ENSP00000443719  

    Human Recombinant Protein Products for ARMC6: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for ARMC6
    OriGene Protein Over-expression Lysate for ARMC6
    OriGene MassSpec for ARMC6 
    OriGene Custom Protein Services for ARMC6
    GenScript Custom Purified and Recombinant Proteins Services for ARMC6
    Novus Biologicals ARMC6 Protein
    Novus Biologicals ARMC6 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ARMC6 


    ARMC6 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ARMC6
    GenScript Custom Superior Antibodies Services for ARMC6
    Novus Biologicals ARMC6 Antibodies
    Abcam antibodies for ARMC6
    Cloud-Clone Corp. Antibodies for ARMC6 
    ThermoFisher Antibodies for ARMC6
    LSBio Antibodies in human, mouse, rat for ARMC6 

    Assay Products for ARMC6: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ARMC6
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ARMC6
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ARMC6 
    Cloud-Clone Corp. CLIAs for ARMC6


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARMC: Armadillo repeat containing

    3 InterPro protein domains:
     IPR011989 ARM-like
     IPR000225 Armadillo
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q6NXE6

    ProtoNet protein and cluster: Q6NXE6

    1 Blocks protein domain: IPB000225 Armadillo repeat

    UniProtKB/Swiss-Prot: ARMC6_HUMAN, Q6NXE6
    Similarity: Belongs to the ARMC6 family
    Similarity: Contains 4 ARM repeats


    ARMC6 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
         
    ARMC6 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARMC6 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ARMC6

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARMC6 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARMC6 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARMC6
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ARMC6
    SwitchGear 3'UTR luciferase reporter plasmidARMC6 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ARMC6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARMC6

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ARMC6
    Sirion Biotech Customized adenovirus for overexpression of ARMC6

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for ARMC6 (see all 8)
    OriGene ORF clones in mouse, rat for ARMC6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ARMC6 (NM_033415)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMC6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC6
    Sirion Biotech Customized lentivirus for stable overexpression of ARMC6 
                         Customized lentivirus expression plasmids for stable overexpression of ARMC6 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ARMC6
    Search LifeMap BioReagents cell lines for ARMC6
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC6


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARMC6

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/15 Interacting proteins for ARMC6 (Q6NXE63 ENSP000002699324) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    AP1S1P619663, ENSP000003366664I2D: score=2 STRING: ENSP00000336666
    STK36Q9NRP73, ENSP000002957094I2D: score=2 STRING: ENSP00000295709
    WRAP73Q9P2S53, ENSP000002707084I2D: score=2 STRING: ENSP00000270708
    PSMD6Q150083, ENSP000002959014I2D: score=1 STRING: ENSP00000295901
    SAP18O004223, ENSP000003719734I2D: score=1 STRING: ENSP00000371973
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARMC6

    Search CenterWatch for drugs/clinical trials and news about ARMC6

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARMC6 gene (2 alternative transcripts): 
    NM_001199196.1  NM_033415.3  

    Unigene Cluster for ARMC6:

    Armadillo repeat containing 6
    Hs.77876  [show with all ESTs]
    Unigene Representative Sequence: NM_001199196
    18/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000392335(uc002nlc.3) ENST00000535612(uc002nld.3 uc010xqm.2)
    ENST00000537263 ENST00000540707 ENST00000541725 ENST00000269932 ENST00000546344(uc010xql.2)
    ENST00000540792 ENST00000536098 ENST00000541898 ENST00000539985 ENST00000543877
    ENST00000545091 ENST00000535288 ENST00000538663 ENST00000392336 ENST00000535758
    ENST00000535478
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ARMC6
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate ARMC6
    SwitchGear 3'UTR luciferase reporter plasmidARMC6 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for ARMC6
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARMC6
    Clone
    Products:
         
    OriGene clones in human, mouse for ARMC6 (see all 8)
    OriGene ORF clones in mouse, rat for ARMC6
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ARMC6 (NM_033415)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMC6
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC6
    Sirion Biotech Customized lentivirus for stable overexpression of ARMC6 
                         Customized lentivirus expression plasmids for stable overexpression of ARMC6 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ARMC6
    OriGene qSTAR qPCR primer pairs in human, mouse for ARMC6
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARMC6
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARMC6
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARMC6

    Additional mRNA sequence: 

    AK295488.1 AK303914.1 BC003700.1 BC056161.1 BC067125.1 BX648486.1 CR749678.1 Z36779.1 

    17 DOTS entries:

    DT.444151  DT.100812701  DT.91770965  DT.91770971  DT.95347755  DT.95327921  DT.100682839  DT.95347758 
    DT.95302583  DT.121472250  DT.100812688  DT.100812690  DT.100812692  DT.97847966  DT.86857160  DT.100812695 
    DT.95356501 

    24/317 AceView cDNA sequences (see all 317):

    BQ637345 CB150509 AI815517 CD672850 BQ086263 BC003700 BU156844 BM021391 
    AI521751 BM804237 BQ011144 BG286616 H92780 BP369825 BQ959051 BC067125 
    BI755321 BG749605 BM694621 BQ012036 AA300953 AL556156 BU526477 BX648486 

    GeneLoc Exon Structure

    5/9 Alternative Splicing Database (ASD) splice patterns (SP) for ARMC6 (see all 9)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f · 1g ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d · 7e · 7f ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12a ·
    SP1:                                      -                 -     -                                                                                             
    SP2:                                      -                       -                                                                                             
    SP3:                                                        -                                                                                                   
    SP4:                                                                                                  -     -     -     -                                       
    SP5:                                      -     -     -     -     -                                                                                             

    ExUns: 12b
    SP1:      
    SP2:      
    SP3:      
    SP4:      
    SP5:      


    ECgene alternative splicing isoforms for ARMC6

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARMC6 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGGCCTCTG
    ARMC6 Expression
    About this image


    See ARMC6 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARMC6

    SOURCE GeneReport for Unigene cluster: Hs.77876
        SABiosciences Custom PCR Arrays for ARMC6
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ARMC6
    OriGene qSTAR qPCR primer pairs in human, mouse for ARMC6
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARMC6
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARMC6
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARMC6
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC6

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ARMC6 gene from 7/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Armc61 , 5 armadillo repeat containing 61, 5 81.3(n)1
    83.94(a)1
      8 (34.15 cM)5
    768131  NM_133972.21  NP_598733.21 
     702201725 
    chicken
    (Gallus gallus)
    Aves ARMC61 armadillo repeat containing 6 67.37(n)
    65.4(a)
      420112  XM_001233054.2  XP_001233055.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.204872 Xenopus laevis transcribed sequence with weak similarity more 72.18(n)    CD360558.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5554251 armadillo repeat-containing protein 6-like 64.37(n)
    63.01(a)
      555425  XM_677924.5  XP_683016.5 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG57211 CG5721 46.59(n)
    34.67(a)
      37084  NM_137462.3  NP_611306.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT4G339451 armadillo/beta-catenin-like repeat-containing protein 39.04(n)
    28.54(a)
      829540  NM_119555.3  NP_567944.1 
    rice
    (Oryza sativa)
    Liliopsida Os02g07612001 hypothetical protein 40.59(n)
    28.34(a)
      4330807  NM_001054730.1  NP_001048195.1 


    ENSEMBL Gene Tree for ARMC6 (if available)
    TreeFam Gene Tree for ARMC6 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARMC6 gene
    6 SIMAP similar genes for ARMC6 using alignment to 17 protein entries:     ARMC6_HUMAN (see all proteins):
    DKFZp762A1314    RTBDN    APOPT1    ZNF554    ZNF547    VPS45

    ARMC6 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/552 SNPs in ARMC6 are shown (see all 552)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1828399201,2
    --19146419(+) TCAGTC/TAGCTC 2 -- int10--------
    rs1889364771,2
    C--19146505(+) AGGCAA/GCCACC 2 -- int10--------
    rs347504021,2
    C,F--19146577(+) AATCAA/G/TTTAGA 2 -- int12NA 4
    rs2012844601,2
    --19146577(+) ATCAG-/TTTAGA 2 -- int10--------
    rs1995330871,2
    --19146580(+) CAGTT-/AGAA  
            
    AGCTT
    2 -- int10--------
    rs730089281,2
    C,F--19146729(+) GGTCAC/TAGGTA 2 -- int12Minor allele frequency- T:0.07NA 122
    rs1181040251,2
    C,F--19146732(+) CACAGG/TTAGAG 2 -- int11Minor allele frequency- T:0.02NA 120
    rs81061461,2
    C,F,H--19146750(+) attgcG/Tttctt 2 -- int117Minor allele frequency- T:0.20NS EA NA WA CSA 636
    rs1492751171,2
    --19146788(+) ATACAC/TGATTT 2 -- int10--------
    rs1504683181,2
    C--19146866(+) TGTTT-/GCTTGT 2 -- int10--------

    HapMap Linkage Disequilibrium report for ARMC6 (19144384 - 19170563 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ARMC6:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv833779CNV Loss17160897
    nsv833778CNV Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing ARMC6
    DNA2.0 Custom Variant and Variant Library Synthesis for ARMC6

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for ARMC6:    About MalaCards
    pancreatic cancer    pancreatitis


    ARMC6 for disorders           About GeneDecksing


    Export disorders for ARMC6 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARMC6 gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with ARMC6)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (2002)
    4. Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach. (PubMed id 23464991)1 Scifo E....Lalowski M. (2013)
    5. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    8. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Ubiquitin ligase substrate identification through qua ntitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 93436 HGNC: 25049 AceView: ARMC6 Ensembl:ENSG00000105676 euGenes: HUgn93436
    ECgene: ARMC6 H-InvDB: ARMC6

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARMC6 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARMC6 gene:
    Search GeneIP for patents involving ARMC6

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ARMC6  
     OriGene qPCR primer pairs and template standards for ARMC6   OriGene Protein Over-expression Lysate for ARMC6  
     OriGene MassSpec something-or-other for ARMC6   OriGene clones in human, mouse for ARMC6  
     OriGene qSTAR qPCR primer pairs in human, mouse for ARMC6   OriGene Purified Protein for ARMC6  
     OriGene ORF clones in mouse, rat for ARMC6   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ARMC6   OriGene Custom Protein Services for ARMC6  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARMC6
     QIAGEN SeqTarget long-range PCR primers for resequencing ARMC6
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARMC6
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARMC6
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARMC6
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARMC6
     GenScript Custom Purified and Recombinant Proteins Services for ARMC6 GenScript cDNA clones with any tag delivered in your preferred vector for ARMC6
     GenScript Custom Assay Services for ARMC6 GenScript Custom Superior Antibodies Services for ARMC6
     GenScript Custom overexpressing Cell Line Services for ARMC6 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in ARMC6 promoter
     Search Chromatin IP Primers for ARMC6
     RT2 qPCR Primer Assay in human, mouse, rat ARMC6
     Search GNC Networks for ARMC6
     SABiosciences Custom PCR Arrays for ARMC6
     Search Tocris compounds for ARMC6
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     ARMC6 antibodies
     ARMC6 proteins
     ARMC6 lysates
     Antibodies for ARMC6
     See all of Abcam's Antibodies, Kits and Proteins for ARMC6
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for ARMC6
     Antibodies for ARMC6
     ELISAs for ARMC6
     CLIAs for ARMC6
     Search LifeMap BioReagents cell lines for ARMC6
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC6
     SwitchGear 3'UTR luciferase reporter plasmids for ARMC6
     SwitchGear Promoter luciferase reporter plasmids for ARMC6
     ThermoFisher Antibodies for ARMC6
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC6
     inGenious Targeting Laboratory - Custom generated mouse model solutions for ARMC6
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for ARMC6
    Customized:
     lentivirus for stable overexpression of ARMC6
     lentivirus expression plasmids for stable overexpression of ARMC6
     adenovirus for overexpression of ARMC6
     LSBio Antibodies in human, mouse, rat for ARMC6
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ARMC6 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4