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ARMC4 Gene

protein-coding   GIFtS: 50
GCID: GC10M028064

Armadillo Repeat Containing 4

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Armadillo Repeat Containing 41 2
CILD232 5
Armadillo Repeat-Containing Protein 42

External Ids:    HGNC: 255831   Entrez Gene: 551302   Ensembl: ENSG000001691267   OMIM: 6154085   UniProtKB: Q5T2S83   

Export aliases for ARMC4 gene to outside databases

Previous GC identifers: GC10M028105 GC10M028141 GC10M027818


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ARMC4 Gene:
ARMC4 (armadillo repeat containing 4) is a protein-coding gene. Diseases associated with ARMC4 include ciliary dyskinesia, primary, 23, and ciliary dyskinesia, primary, 19. An important paralog of this gene is ARMC3.

UniProtKB/Swiss-Prot: ARMC4_HUMAN, Q5T2S8
Function: Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000010.11  NT_008705.17  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARMC4 gene promoter:
         Pbx1a   MEF-2   Bach2   Nkx2-5   MEF-2A   Nkx6-1   POU2F1   POU2F1a   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARMC4 promoter sequence
   Search Chromatin IP Primers for ARMC4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARMC4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p12.1-p11.23   Ensembl cytogenetic band:  10p12.1   HGNC cytogenetic band: 10p12.1-p11.23

ARMC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARMC4 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M028064:  view genomic region     (about GC identifiers)

Start:
28,064,115 bp from pter      End:
28,287,977 bp from pter
Size:
223,863 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ARMC4_HUMAN, Q5T2S8 (See protein sequence)
Recommended Name: Armadillo repeat-containing protein 4  
Size: 1044 amino acids; 115679 Da
Secondary accessions: A8K906 Q9H0C0

Explore the universe of human proteins at neXtProt for ARMC4: NX_Q5T2S8

Explore proteomics data for ARMC4 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ARMC4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001276949.1  NP_001276950.1  NP_060546.2  

    ENSEMBL proteins: 
     ENSP00000306410   ENSP00000398155   ENSP00000473438   ENSP00000443208   ENSP00000441076  
     ENSP00000239715  

    ARMC4 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for ARMC4

    ARMC4 Assay Products:

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    Cloud-Clone Corp. ELISAs for ARMC4
    Cloud-Clone Corp. CLIAs for ARMC4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ARMC: Armadillo repeat containing

    5 InterPro protein domains:
     IPR011989 ARM-like
     IPR000225 Armadillo
     IPR023231 GSKIP_dom
     IPR026959 ARMC4
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q5T2S8

    ProtoNet protein and cluster: Q5T2S8

    UniProtKB/Swiss-Prot: ARMC4_HUMAN, Q5T2S8
    Similarity: Contains 10 ARM repeats


    ARMC4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARMC4_HUMAN, Q5T2S8
    Function: Ciliary protein that may be involved in a late step of axonemal outer dynein arm assembly

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding ----
         
    ARMC4 for ontologies           About GeneDecksing


    Phenotypes:
         9 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Armc4):
     cardiovascular system  digestive/alimentary  growth/size/body  hematopoietic system  immune system 
     mortality/aging  muscle  nervous system  respiratory system 

    ARMC4 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ARMC4
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ARMC4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ARMC4
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ARMC4

    miRNA
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    Block miRNA regulation of human, mouse, rat ARMC4 using miScript Target Protectors
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    SwitchGear 3'UTR luciferase reporter plasmidARMC4 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for ARMC4
    Predesigned siRNA for gene silencing in human, mouse, rat ARMC4

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: ARMC4 (NM_018076)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC4

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ARMC4_HUMAN, Q5T2S8: Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IEA--
    GO:0005856cytoskeleton IEA--
    GO:0005929cilium IEA--

    ARMC4 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARMC4
    Interactions:

        Search GeneGlobe Interaction Network for ARMC4

    1 Interacting protein for ARMC4 (Q5T2S83) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK6Q166593I2D: score=2 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030030cell projection organization IEA--

    ARMC4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARMC4



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ARMC4 gene (3 alternative transcripts): 
    NM_001290020.1  NM_001290021.1  NM_018076.3  

    Unigene Cluster for ARMC4:

    Armadillo repeat containing 4
    Hs.127530  [show with all ESTs]
    Unigene Representative Sequence: BC085611
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000481659 ENST00000305242(uc009xky.3 uc001itz.3) ENST00000467083
    ENST00000480504 ENST00000434029 ENST00000486279 ENST00000537576(uc010qdt.2 uc010qdu.1)
    ENST00000545014(uc010qds.2) ENST00000239715
    miRNA
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    Block miRNA regulation of human, mouse, rat ARMC4 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate ARMC4
    SwitchGear 3'UTR luciferase reporter plasmidARMC4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ARMC4
    Predesigned siRNA for gene silencing in human, mouse, rat ARMC4
    Clone
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    OriGene clones in human, mouse for ARMC4 (see all 6)
    OriGene ORF clones in mouse, rat for ARMC4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: ARMC4 (NM_018076)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARMC4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARMC4
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for ARMC4
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ARMC4
      QuantiTect SYBR Green Assays in human, mouse, rat ARMC4
      QuantiFast Probe-based Assays in human, mouse, rat ARMC4

    Additional mRNA sequence: 

    AK001238.1 AK001679.1 AK292521.1 AK301708.1 AK302048.1 AK302419.1 AK302627.1 AL136859.1 
    BC085611.1 BC140846.1 

    10 DOTS entries:

    DT.433073  DT.121240138  DT.100688914  DT.92428438  DT.121240184  DT.97833721  DT.65287038  DT.75106778 
    DT.100688913  DT.121240178 

    Selected AceView cDNA sequences (see all 66):

    BP872991 NM_018076 AL136859 AU124293 AW991221 BG183534 AU132976 CK000961 
    BE882569 BP371279 AK001679 AA861811 CN478612 CN478596 BX279799 BQ774953 
    BM975631 BU675734 AI016769 BG196505 AK001238 BM457947 BU528460 BE501375 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ARMC4    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22a · 22b
    SP1:                                                              -     -                                                           -               
    SP2:                                                                                                                                                
    SP3:                                                                                                                                                


    ECgene alternative splicing isoforms for ARMC4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ARMC4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGATAAGATG
    ARMC4 Expression
    About this image

    ARMC4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARMC4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.127530

    UniProtKB/Swiss-Prot: ARMC4_HUMAN, Q5T2S8
    Tissue specificity: Expressed in respiratory epithelial cells (at protein level)

        Custom PCR Arrays for ARMC4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARMC4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ARMC4 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Armc41 , 5 armadillo repeat containing 41, 5 82.53(n)1
    85.98(a)1
      18 (4.53 cM)5
    749341  NM_001081393.11  NP_001074862.11 
     70882335 
    chicken
    (Gallus gallus)
    Aves ARMC41 armadillo repeat containing 4 70.7(n)
    68.57(a)
      420482  XM_003640636.2  XP_003640684.2 
    lizard
    (Anolis carolinensis)
    Reptilia ARMC46
    armadillo repeat containing 4
    69(a)
    1 ↔ 1
    6(14055560-14149004)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.235642 Xenopus laevis, Similar to hypothetical protein DKFZp434P1735, more 75.75(n)    BC042360.1 
    zebrafish
    (Danio rerio)
    Actinopterygii armc41 armadillo repeat containing 4 61.96(n)
    61.2(a)
      799229  XM_005156229.1  XP_005156286.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG51551 CG5155 52.37(n)
    46.9(a)
      34014  NM_135267.3  NP_609111.1 


    ENSEMBL Gene Tree for ARMC4 (if available)
    TreeFam Gene Tree for ARMC4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ARMC4 gene
    ARMC32  
    4 SIMAP similar genes for ARMC4 using alignment to 6 protein entries:     ARMC4_HUMAN (see all proteins):
    AURA2    CTSS    NF2    FAM175A

    ARMC4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ARMC4
    PGOHUM00000238703


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ARMC4 (see all 3981)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0702284
    Ciliary dyskinesia, primary, 23 (CILD23)4--see VAR_0702282 L W mis40--------
    rs556829031,2
    C--27832977(+) TATAT-/ATA   
       TATAT
    TCCAT
    1 -- int11Minor allele frequency- ATATATAT:0.00NA 2
    rs1411780361,2
    C--28100599(+) TATTT-/TGTTTT 1 -- ds50010--------
    rs28155071,2
    C,F,A,H--28100603(+) TATTTT/GTTTTG 1 -- ds500114Minor allele frequency- G:0.26NA NS WA CSA 363
    rs1879094741,2
    --28100646(+) AAAACA/CAGTTC 1 -- ds50010--------
    rs1482860651,2
    --28100728(+) TGTTGC/GTAAAT 1 -- ds50010--------
    rs1433381681,2
    --28100773(+) TCTGTA/GAGTCA 1 -- ds50010--------
    rs801150071,2
    C,F--28100930(+) GCTTAA/GCTCTA 1 -- ds50012Minor allele frequency- G:0.04WA NA 238
    rs1930924421,2
    --28100992(+) CCGTGA/GGTTGC 1 -- ds50010--------
    rs1120034681,2
    C--28101061(+) GGAACT/AGTGGA 1 -- ds50011Minor allele frequency- A:0.50NA 2

    HapMap Linkage Disequilibrium report for ARMC4 (28064115 - 28287977 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for ARMC4 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2734761CNV Deletion23290073
    esv2734606CNV Deletion23290073
    esv3437CNV Deletion18987735
    esv2734739CNV Deletion23290073
    esv2734750CNV Deletion23290073
    esv271730CNV Insertion20981092
    nsv831813CNV Loss17160897
    nsv25294CNV Loss16902084
    nsv831815CNV Loss17160897
    esv6382CNV Loss19470904

    Human Gene Mutation Database (HGMD): ARMC4
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ARMC4
    DNA2.0 Custom Variant and Variant Library Synthesis for ARMC4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615408   
    OMIM disorders: 615451  
    UniProtKB/Swiss-Prot: ARMC4_HUMAN, Q5T2S8
  • Ciliary dyskinesia, primary, 23 (CILD23) [MIM:615451]: A disorder characterized by abnormalities of
    motile cilia. Respiratory infections leading to chronic inflammation and bronchiectasis are recurrent, due to
    defects in the respiratory cilia. Patients may exhibit randomization of left-right body asymmetry and situs
    inversus, due to dysfunction of monocilia at the embryonic node. Primary ciliary dyskinesia associated with situs
    inversus is referred to as Kartagener syndrome. Note=The disease is caused by mutations affecting the gene
    represented in this entry. Contrary to the wild-type protein, disease-causing variant Trp-927 is unable to rescue
    the phenotype (randomization of heart looping) of the morpholino knockdown of the orthologous protein in
    zebrafish (PubMed:23849778)

  • 5 diseases for ARMC4:    
    About MalaCards
    ciliary dyskinesia, primary, 23    ciliary dyskinesia, primary, 19    obesity    alzheimer's disease
    malaria


    ARMC4 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ARMC4
    Human Genome Epidemiology (HuGE) Navigator: ARMC4 (2 documents)

    Export disorders for ARMC4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ARMC4 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with ARMC4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. ARMC4 mutations cause primary ciliary dyskinesia with randomization of left/right body asymmetry. (PubMed id 23849778)1, 2 Hjeij R....Omran H. (Am. J. Hum. Genet. 2013)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    7. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PubMed id 23251661)1 Comuzzie A.G....Butte N.F. (PLoS ONE 2012)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55130 HGNC: 25583 AceView: ARMC4 Ensembl:ENSG00000169126 euGenes: HUgn55130
    ECgene: ARMC4 H-InvDB: ARMC4

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ARMC4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ARMC4 gene:
    Search GeneIP for patents involving ARMC4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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