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Aliases for ARMC2 Gene

Aliases for ARMC2 Gene

  • Armadillo Repeat Containing 2 2 3
  • Armadillo Repeat-Containing Protein 2 3
  • BA787I22.1 3

External Ids for ARMC2 Gene

Summaries for ARMC2 Gene

GeneCards Summary for ARMC2 Gene

ARMC2 (Armadillo Repeat Containing 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMC2 Gene

Genomics for ARMC2 Gene

Genomic Location for ARMC2 Gene

Start:
108,848,414 bp from pter
End:
108,974,472 bp from pter
Size:
126,059 bases
Orientation:
Plus strand

Genomic View for ARMC2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARMC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMC2 Gene

Regulatory Elements for ARMC2 Gene

Proteins for ARMC2 Gene

  • Protein details for ARMC2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NEN0-ARMC2_HUMAN
    Recommended name:
    Armadillo repeat-containing protein 2
    Protein Accession:
    Q8NEN0
    Secondary Accessions:
    • A8K8Y4
    • B4DGF5
    • G5E993
    • Q5VVY8
    • Q9H0K9

    Protein attributes for ARMC2 Gene

    Size:
    867 amino acids
    Molecular mass:
    96867 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH30603.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAF85188.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI16717.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for ARMC2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARMC2 Gene

Proteomics data for ARMC2 Gene at MOPED

Post-translational modifications for ARMC2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARMC2 Gene

No data available for DME Specific Peptides for ARMC2 Gene

Domains for ARMC2 Gene

Gene Families for ARMC2 Gene

HGNC:
  • ARMC :Armadillo repeat containing

Protein Domains for ARMC2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

ARMC2_HUMAN
Similarity:
  • Contains 12 ARM repeats.:
    • Q8NEN0
genes like me logo Genes that share domains with ARMC2: view

Function for ARMC2 Gene

Gene Ontology (GO) - Molecular Function for ARMC2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding --
GO:0005515 protein binding IPI 24407287
genes like me logo Genes that share ontologies with ARMC2: view

miRNA for ARMC2 Gene

miRTarBase miRNAs that target ARMC2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for ARMC2 Gene

Localization for ARMC2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARMC2 Gene COMPARTMENTS Subcellular localization image for ARMC2 gene
Compartment Confidence
cytosol 2
nucleus 2
endoplasmic reticulum 1

No data available for Gene Ontology (GO) - Cellular Components for ARMC2 Gene

Pathways for ARMC2 Gene

SuperPathways for ARMC2 Gene

No Data Available

Interacting Proteins for ARMC2 Gene

Selected Interacting proteins: Q8NEN0-ARMC2_HUMAN for ARMC2 Gene via I2D

Symbol External ID(s) Details
IGHG1

Gene Ontology (GO) - Biological Process for ARMC2 Gene

None

No data available for Pathways by source for ARMC2 Gene

Transcripts for ARMC2 Gene

Unigene Clusters for ARMC2 Gene

Armadillo repeat containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARMC2 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^
SP1: - - - - -
SP2: - - - - -
SP3: -
SP4: - - -
SP5: - - -
SP6: - - - - - - -
SP7: - - - - - -
SP8:

ExUns: 16 ^ 17 ^ 18 ^ 19 ^ 20
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:

Relevant External Links for ARMC2 Gene

GeneLoc Exon Structure for
ARMC2
ECgene alternative splicing isoforms for
ARMC2

Expression for ARMC2 Gene

mRNA expression in normal human tissues for ARMC2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ARMC2 Gene

This gene is overexpressed in Testis (5.4).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ARMC2 Gene

SOURCE GeneReport for Unigene cluster for ARMC2 Gene Hs.645481

genes like me logo Genes that share expressions with ARMC2: view

Orthologs for ARMC2 Gene

This gene was present in the common ancestor of animals.

Orthologs for ARMC2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARMC2 36
  • 99.46 (n)
  • 99.19 (a)
ARMC2 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ARMC2 36
  • 87.17 (n)
  • 83.24 (a)
ARMC2 37
  • 76 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARMC2 36
  • 88.47 (n)
  • 85.8 (a)
ARMC2 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Armc2 36
  • 77.4 (n)
  • 74 (a)
Armc2 16
Armc2 37
  • 71 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 76 (a)
OneToMany
-- 37
  • 76 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia ARMC2 37
  • 55 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Armc2 36
  • 76.92 (n)
  • 74.15 (a)
chicken
(Gallus gallus)
Aves ARMC2 36
  • 65.93 (n)
  • 58.36 (a)
ARMC2 37
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARMC2 37
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia armc2 36
  • 60.55 (n)
  • 53.32 (a)
zebrafish
(Danio rerio)
Actinopterygii armc2 36
  • 53.07 (n)
  • 48.13 (a)
armc2 37
  • 44 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG32668 37
  • 24 (a)
OneToOne
Species with no ortholog for ARMC2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for ARMC2 Gene

ENSEMBL:
Gene Tree for ARMC2 (if available)
TreeFam:
Gene Tree for ARMC2 (if available)

Paralogs for ARMC2 Gene

No data available for Paralogs for ARMC2 Gene

Variants for ARMC2 Gene

Sequence variations from dbSNP and Humsavar for ARMC2 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs434225 -- 108,962,925(+) gccca(A/G)aagtt intron-variant
rs445221 -- 108,968,389(-) TGCAC(A/G)AGGTG intron-variant
rs911475 -- 108,941,984(-) TCCTT(A/G)TAGCC intron-variant
rs911476 -- 108,941,776(-) CACTT(A/C)AAAAG intron-variant
rs911477 -- 108,941,704(-) GAACC(A/G)GGAAT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ARMC2 Gene

Variant ID Type Subtype PubMed ID
nsv830768 CNV Gain 17160897
esv2673947 CNV Deletion 23128226
esv2656715 CNV Deletion 23128226
nsv886532 CNV Loss 21882294

Relevant External Links for ARMC2 Gene

HapMap Linkage Disequilibrium report
ARMC2

Disorders for ARMC2 Gene

Relevant External Links for ARMC2

Genetic Association Database (GAD)
ARMC2
Human Genome Epidemiology (HuGE) Navigator
ARMC2
genes like me logo Genes that share disorders with ARMC2: view

No data available for UniProtKB/Swiss-Prot for ARMC2 Gene

Publications for ARMC2 Gene

  1. Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts. (PMID: 18978678) Vieira A.R. … Marazita M.L. (Genet. Med. 2008) 3 49
  2. Inherited genetic variant predisposes to aggressive but not indolent prostate cancer. (PMID: 20080650) Xu J. … Isaacs W.B. (Proc. Natl. Acad. Sci. U.S.A. 2010) 3 49
  3. Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function. (PMID: 21946350) Soler Artigas M. … Tobin M.D. (Nat. Genet. 2011) 3 49
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  5. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4

Products for ARMC2 Gene

Sources for ARMC2 Gene

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