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Aliases for ARMC12 Gene

Aliases for ARMC12 Gene

  • Armadillo Repeat Containing 12 2 3
  • C6orf81 3 4
  • Armadillo Repeat-Containing Protein 12 3
  • Chromosome 6 Open Reading Frame 81 2

External Ids for ARMC12 Gene

Previous HGNC Symbols for ARMC12 Gene

  • C6orf81

Previous GeneCards Identifiers for ARMC12 Gene

  • GC06P035705
  • GC06P035821
  • GC06P036312
  • GC06P037299

Summaries for ARMC12 Gene

GeneCards Summary for ARMC12 Gene

ARMC12 (Armadillo Repeat Containing 12) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARMC12 Gene

Genomics for ARMC12 Gene

Genomic Location for ARMC12 Gene

Start:
35,733,790 bp from pter
End:
35,749,079 bp from pter
Size:
15,290 bases
Orientation:
Plus strand

Genomic View for ARMC12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for ARMC12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARMC12 Gene

No data available for Regulatory Elements for ARMC12 Gene

Proteins for ARMC12 Gene

  • Protein details for ARMC12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T9G4-ARM12_HUMAN
    Recommended name:
    Armadillo repeat-containing protein 12
    Protein Accession:
    Q5T9G4
    Secondary Accessions:
    • Q8NEB2
    • Q96LL8

    Protein attributes for ARMC12 Gene

    Size:
    340 amino acids
    Molecular mass:
    38632 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ARMC12 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARMC12 Gene

Proteomics data for ARMC12 Gene at MOPED

Post-translational modifications for ARMC12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARMC12 Gene

No data available for DME Specific Peptides for ARMC12 Gene

Domains for ARMC12 Gene

Gene Families for ARMC12 Gene

HGNC:
  • ARMC :Armadillo repeat containing

Protein Domains for ARMC12 Gene

Graphical View of Domain Structure for InterPro Entry

Q5T9G4

UniProtKB/Swiss-Prot:

ARM12_HUMAN :
  • Q5T9G4
Similarity:
  • Contains 3 ARM repeats.
genes like me logo Genes that share domains with ARMC12: view

No data available for Suggested Antigen Peptide Sequences for ARMC12 Gene

Function for ARMC12 Gene

Gene Ontology (GO) - Molecular Function for ARMC12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005488 binding --
genes like me logo Genes that share ontologies with ARMC12: view

Phenotypes for ARMC12 Gene

GenomeRNAi human phenotypes for ARMC12:
genes like me logo Genes that share phenotypes with ARMC12: view

Animal Model Products

CRISPR Products

miRNA for ARMC12 Gene

miRTarBase miRNAs that target ARMC12

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARMC12

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for ARMC12 Gene

Localization for ARMC12 Gene

Gene Ontology (GO) - Cellular Components for ARMC12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 21630459
genes like me logo Genes that share ontologies with ARMC12: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ARMC12 Gene

Pathways for ARMC12 Gene

SuperPathways for ARMC12 Gene

No Data Available

Interacting Proteins for ARMC12 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000288065%0d%0a9606.ENSP00000363822%0d%0a9606.ENSP00000381891%0d%0a
Selected Interacting proteins: ENSP00000288065 Q5T9G4-ARM12_HUMAN for ARMC12 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for ARMC12 Gene

None

No data available for Pathways by source for ARMC12 Gene

Transcripts for ARMC12 Gene

Unigene Clusters for ARMC12 Gene

Armadillo repeat containing 12:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for ARMC12

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ARMC12 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c
SP1: - -
SP2:
SP3: -

Relevant External Links for ARMC12 Gene

GeneLoc Exon Structure for
ARMC12
ECgene alternative splicing isoforms for
ARMC12

Expression for ARMC12 Gene

mRNA expression in normal human tissues for ARMC12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for ARMC12 Gene

This gene is overexpressed in Testis (17.9).

Protein differential expression in normal tissues for ARMC12 Gene

This gene is overexpressed in Testis (26.5), Fetal gut (16.9), Spleen (13.4), and Ovary (6.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for ARMC12 Gene

SOURCE GeneReport for Unigene cluster for ARMC12 Gene Hs.533066

genes like me logo Genes that share expressions with ARMC12: view

Expression partners for ARMC12 Gene

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for ARMC12 Gene

Orthologs for ARMC12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for ARMC12 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia ARMC12 35
  • 87.5 (n)
  • 86.36 (a)
ARMC12 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ARMC12 35
  • 89.55 (n)
  • 88.01 (a)
ARMC12 36
  • 87 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Armc12 35
  • 84.12 (n)
  • 83.73 (a)
Armc12 16
Armc12 36
  • 82 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ARMC12 35
  • 98.79 (n)
  • 98.79 (a)
ARMC12 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Armc12 35
  • 81.67 (n)
  • 82.65 (a)
oppossum
(Monodelphis domestica)
Mammalia ARMC12 36
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ARMC12 36
  • 61 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 54 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
Species with no ortholog for ARMC12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ARMC12 Gene

ENSEMBL:
Gene Tree for ARMC12 (if available)
TreeFam:
Gene Tree for ARMC12 (if available)

Paralogs for ARMC12 Gene

No data available for Paralogs for ARMC12 Gene

Variants for ARMC12 Gene

Sequence variations from dbSNP and Humsavar for ARMC12 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1075091 -- 35,745,710(-) agcga(C/G)gtccc intron-variant
rs1075092 -- 35,745,649(-) taata(G/T)caaaa intron-variant
rs1581858 -- 35,739,086(-) cctcc(A/G)tttag intron-variant
rs1590601 -- 35,739,055(-) ttata(A/C/T)aaaaa intron-variant
rs1831030 -- 35,739,156(-) gccca(A/G)ccctc intron-variant

Relevant External Links for ARMC12 Gene

HapMap Linkage Disequilibrium report
ARMC12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for ARMC12 Gene

Disorders for ARMC12 Gene

No disorders were found for ARMC12 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for ARMC12 Gene

Publications for ARMC12 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3

Products for ARMC12 Gene

Sources for ARMC12 Gene

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