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Aliases for ARL9 Gene

Aliases for ARL9 Gene

  • ADP Ribosylation Factor Like GTPase 9 2 3 5
  • ADP-Ribosylation Factor Like GTPase 9 2

External Ids for ARL9 Gene

Previous GeneCards Identifiers for ARL9 Gene

  • GC00U914119
  • GC04P057287
  • GC04P057212
  • GC04P057066
  • GC04P057371
  • GC04P053325

Summaries for ARL9 Gene

Entrez Gene Summary for ARL9 Gene

  • ARL9 is a member of the small GTPase protein family with a high degree of similarity to ARF (MIM 103180) proteins of the RAS superfamily.[supplied by OMIM, Nov 2008]

GeneCards Summary for ARL9 Gene

ARL9 (ADP Ribosylation Factor Like GTPase 9) is a Protein Coding gene. GO annotations related to this gene include GTP binding. An important paralog of this gene is ARL11.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL9 Gene

Genomics for ARL9 Gene

Regulatory Elements for ARL9 Gene

Promoters for ARL9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ARL9 on UCSC Golden Path with GeneCards custom track

Genomic Location for ARL9 Gene

Chromosome:
4
Start:
56,505,209 bp from pter
End:
56,524,448 bp from pter
Size:
19,240 bases
Orientation:
Plus strand

Genomic View for ARL9 Gene

Genes around ARL9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARL9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARL9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL9 Gene

Proteins for ARL9 Gene

  • Protein details for ARL9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6T311-ARL9_HUMAN
    Recommended name:
    ADP-ribosylation factor-like protein 9
    Protein Accession:
    Q6T311

    Protein attributes for ARL9 Gene

    Size:
    187 amino acids
    Molecular mass:
    20755 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ARL9 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for ARL9 Gene

Proteomics data for ARL9 Gene at MOPED

Post-translational modifications for ARL9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ARL9 Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

  • Santa Cruz Biotechnology (SCBT) Antibodies for ARL9

No data available for DME Specific Peptides for ARL9 Gene

Domains & Families for ARL9 Gene

Gene Families for ARL9 Gene

Protein Domains for ARL9 Gene

Suggested Antigen Peptide Sequences for ARL9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q6T311

UniProtKB/Swiss-Prot:

ARL9_HUMAN :
  • Belongs to the small GTPase superfamily. Arf family.
Family:
  • Belongs to the small GTPase superfamily. Arf family.
genes like me logo Genes that share domains with ARL9: view

Function for ARL9 Gene

genes like me logo Genes that share phenotypes with ARL9: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ARL9 Gene

Localization for ARL9 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for ARL9 Gene COMPARTMENTS Subcellular localization image for ARL9 gene
Compartment Confidence
cytosol 3
nucleus 2
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for ARL9 Gene

Pathways & Interactions for ARL9 Gene

SuperPathways for ARL9 Gene

No Data Available

Interacting Proteins for ARL9 Gene

Gene Ontology (GO) - Biological Process for ARL9 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ARL9 Gene

Drugs & Compounds for ARL9 Gene

No Compound Related Data Available

Transcripts for ARL9 Gene

mRNA/cDNA for ARL9 Gene

(4) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(32) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ARL9 Gene

ADP-ribosylation factor-like 9:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ARL9 Gene

No ASD Table

Relevant External Links for ARL9 Gene

GeneLoc Exon Structure for
ARL9
ECgene alternative splicing isoforms for
ARL9

Expression for ARL9 Gene

mRNA expression in normal human tissues for ARL9 Gene

mRNA differential expression in normal tissues according to GTEx for ARL9 Gene

This gene is overexpressed in Testis (x10.4).

SOURCE GeneReport for Unigene cluster for ARL9 Gene Hs.444449

genes like me logo Genes that share expression patterns with ARL9: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for ARL9 Gene

Orthologs for ARL9 Gene

This gene was present in the common ancestor of animals.

Orthologs for ARL9 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ARL9 35
  • 99.46 (n)
  • 98.37 (a)
ARL9 36
  • 65 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ARL9 36
  • 43 (a)
OneToOne
ARL9 35
  • 89.89 (n)
  • 87.7 (a)
dog
(Canis familiaris)
Mammalia ARL9 35
  • 90.24 (n)
  • 88.62 (a)
ARL9 36
  • 37 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Arl9 16
Arl9 35
  • 86.98 (n)
  • 89.06 (a)
Arl9 36
  • 44 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia ARL9 36
  • 53 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia ARL9 36
  • 40 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Arl9 35
  • 83.61 (n)
  • 82.79 (a)
chicken
(Gallus gallus)
Aves ARL9 35
  • 71.82 (n)
  • 67.48 (a)
ARL9 36
  • 38 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia ARL9 36
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia arl9 35
  • 63.66 (n)
  • 60.66 (a)
Str.15113 35
zebrafish
(Danio rerio)
Actinopterygii arl9 36
  • 26 (a)
OneToOne
arl9 35
  • 55.65 (n)
  • 52.07 (a)
fruit fly
(Drosophila melanogaster)
Insecta Gie 36
  • 18 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea arl-8 36
  • 19 (a)
OneToMany
Species with no ortholog for ARL9:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for ARL9 Gene

ENSEMBL:
Gene Tree for ARL9 (if available)
TreeFam:
Gene Tree for ARL9 (if available)

Paralogs for ARL9 Gene

Paralogs for ARL9 Gene

(19) SIMAP similar genes for ARL9 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with ARL9: view

Variants for ARL9 Gene

Sequence variations from dbSNP and Humsavar for ARL9 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs4299654 -- 56,513,115(+) TTGAG(A/T)TTTAA intron-variant
rs4865108 -- 56,504,308(+) CCTGG(A/G)CAACA upstream-variant-2KB
rs4865109 -- 56,506,788(+) CAGTT(G/T)TGTGT intron-variant
rs4865111 -- 56,517,472(+) CAATA(C/T)GTTGT intron-variant
rs4865112 -- 56,520,096(+) ctccc(A/G)ggttc intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ARL9 Gene

Variant ID Type Subtype PubMed ID
nsv829941 CNV Loss 17160897
esv2657721 CNV Deletion 23128226

Variation tolerance for ARL9 Gene

Residual Variation Intolerance Score: 75.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.37; 27.04% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ARL9 Gene

HapMap Linkage Disequilibrium report
ARL9

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ARL9 Gene

Disorders for ARL9 Gene

Relevant External Links for ARL9

Genetic Association Database (GAD)
ARL9
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ARL9

No disorders were found for ARL9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARL9 Gene

Publications for ARL9 Gene

  1. Rasl11a, member of a novel small monomeric GTPase gene family, is differentially expressed in prostate tumors. (PMID: 15033445) Louro R. … Reis E.M. (Biochem. Biophys. Res. Commun. 2004) 3 4 67
  2. Genome-scale RNAi screen for host factors required for HIV replication. (PMID: 18976975) Zhou H. … Espeseth A.S. (Cell Host Microbe 2008) 3

Products for ARL9 Gene

Sources for ARL9 Gene

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