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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARL6IP5 Gene

protein-coding   GIFtS: 54
GCID: GC03P069216

ADP-Ribosylation-Like Factor 6 Interacting Protein 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ADP-Ribosylation-Like Factor 6 Interacting Protein 51 2     ADP-Ribosylation Factor-Like Protein 6-Interacting Protein 52 3
PRA1 Domain Family 31 2     ARL-6-Interacting Protein 52 3
Cytoskeleton-Related Vitamin A-Responsive Protein2 3     addicsin2
Dermal Papilla-Derived Protein 112 3     aip-52
Glutamate Transporter EAAC1-Interacting Protein2 3     Cytoskeleton Related Vitamin A Responsive Protein2
Prenylated Rab Acceptor Protein 22 3     Dermal Papilla Derived Protein 112
Protein JWa2 3     Glutamate Transporter EEAC1-Associated Protein2
Putative MAPK-Activating Protein PM272 3     hp222
DERP112 3     jmx2
GTRAP3-182 3     PRA1 Family Protein 32
JM52 3     Putative MAPK Activating Protein PM272
JWA2 3     Aip-53
PRAF32 3     PRA23

External Ids:    HGNC: 169371   Entrez Gene: 105502   Ensembl: ENSG000001447467   OMIM: 6057095   UniProtKB: O759153   

Export aliases for ARL6IP5 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARL6IP5 Gene:
Expression of this gene is affected by vitamin A. The encoded protein of this gene may be associated with the
cytoskeleton. A similar protein in rats may play a role in the regulation of cell differentiation. The rat
protein binds and inhibits the cell membrane glutamate transporter EAAC1. The expression of the rat gene is
upregulated by retinoic acid, which results in a specific reduction in EAAC1-mediated glutamate transport.
(provided by RefSeq, Jul 2008)

GeneCards Summary for ARL6IP5 Gene: 
ARL6IP5 (ADP-ribosylation-like factor 6 interacting protein 5) is a protein-coding gene. Diseases associated with ARL6IP5 include alcohol dependence, and esophageal squamous cell carcinoma. GO annotations related to this gene include protein C-terminus binding. An important paralog of this gene is PRAF2.

UniProtKB/Swiss-Prot: PRAF3_HUMAN, O75915
Function: Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1
glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic (By
similarity)

Gene Wiki entry for ARL6IP5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.2  NT_022459.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARL6IP5 gene promoter:
         MEF-2A   RFX1   p53   MEF-2   aMEF-2   YY1   GATA-2   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARL6IP5 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARL6IP5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARL6IP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p14   Ensembl cytogenetic band:  3p14.1   HGNC cytogenetic band: 3p14

ARL6IP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARL6IP5 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P069216:  view genomic region     (about GC identifiers)

Start:
69,134,090 bp from pter      End:
69,155,239 bp from pter
Size:
21,150 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PRAF3_HUMAN, O75915 (See protein sequence)
Recommended Name: PRA1 family protein 3  
Size: 188 amino acids; 21615 Da
Subunit: Forms multimers. Binds to prenylated RAB1A and RAB3A, to the neuronal glutamate transporter SLC1A1/EAAC1,
and to the ADP-ribosylation like factor ARL6, a member of the Ras superfamily. Does not bind to VAMP2 (By
similarity)
Subcellular location: Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Cytoplasm (By
similarity). Note=Also exists as a soluble form in the cytoplasm. Associated with microtubules (By similarity)
Sequence caution: Sequence=BAD97286.1; Type=Erroneous initiation;
Secondary accessions: B2R6V5 Q53ES3 Q5KU08

Explore the universe of human proteins at neXtProt for ARL6IP5: NX_O75915

Explore proteomics data for ARL6IP5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O75915

  • ARL6IP5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARL6IP5 Protein Expression
    REFSEQ proteins: NP_006398.1  
    ENSEMBL proteins: 
     ENSP00000273258   ENSP00000419374   ENSP00000420138   ENSP00000419021  

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    Cloud-Clone Corp. Proteins for ARL6IP5 

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005783endoplasmic reticulum IDA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    ARL6IP5 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR004895 Prenylated_rab_accept_PRA1

    Graphical View of Domain Structure for InterPro Entry O75915

    ProtoNet protein and cluster: O75915

    UniProtKB/Swiss-Prot: PRAF3_HUMAN, O75915
    Similarity: Belongs to the PRA1 family


    ARL6IP5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PRAF3_HUMAN, O75915
    Function: Regulates intracellular concentrations of taurine and glutamate. Negatively modulates SLC1A1/EAAC1
    glutamate transport activity by decreasing its affinity for glutamate. May be involved in membrane traffic (By
    similarity)
    Induction: By methyl-beta-cyclodextrin (By similarity). Up-regulated upon induced differentiation and in heat
    stress

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008022protein C-terminus binding IEA--
         
    ARL6IP5 for ontologies           About GeneDecksing


    Phenotypes:
         10 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Arl6ip5):
     behavior/neurological  cellular  growth/size  homeostasis/metabolism  immune system 
     integument  nervous system  normal  skeleton  tumorigenesis 

    ARL6IP5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Arl6ip5tm1Tnkk for ARL6IP5

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARL6IP5 
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    SwitchGear 3'UTR luciferase reporter plasmidARL6IP5 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARL6IP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    5/19 Interacting proteins for ARL6IP5 (O759152, 3 ENSP000002732584) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRAF2O608312, 3, ENSP000003655704MINT-58206 MINT-58200 MINT-58205 MINT-58202 I2D: score=3 STRING: ENSP00000365570
    CCR5P516812, 3, ENSP000002923034MINT-58208 I2D: score=2 STRING: ENSP00000292303
    SLC1A1P430053, ENSP000002623524I2D: score=3 STRING: ENSP00000262352
    XRCC1P188873, ENSP000002628874I2D: score=1 STRING: ENSP00000262887
    ARL6Q9H0F73, ENSP000003377224I2D: score=3 STRING: ENSP00000337722
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0015813L-glutamate transport ISS--
    GO:0051051negative regulation of transport IEA--

    ARL6IP5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ARL6IP5 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARL6IP5 (PRAF3)

    2 Novoseek inferred chemical compound relationships for ARL6IP5 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glutamate 49.8 11 12562531 (4), 17646425 (2), 11242046 (2), 15757671 (1)
    retinoic acid 34.8 4 12562531 (2), 11242046 (1)

    Search CenterWatch for drugs/clinical trials and news about ARL6IP5 / PRAF3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARL6IP5 gene: 
    NM_006407.3  

    Unigene Clusters for ARL6IP5:

    ADP-ribosylation-like factor 6 interacting protein 5
    Hs.518060  [show with all ESTs], Hs.745255  [show with all ESTs]
    Unigene Representative Sequences: NM_006407, BC107899
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000273258(uc003dnr.3) ENST00000484921 ENST00000478935 ENST00000470936
    ENST00000485444
    miRNA
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    hsa-miR-3163 hsa-miR-607 hsa-miR-520d-5p hsa-miR-181a-2* hsa-miR-4282 hsa-miR-570 hsa-miR-138 hsa-miR-524-5p
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    Additional mRNA sequence: BC107899.1 

    24/26 DOTS entries (see all 26):

    DT.91908849  DT.455983  DT.100888798  DT.100888794  DT.100888799  DT.120878674  DT.100888804  DT.120878723 
    DT.95172185  DT.100888792  DT.100888810  DT.97862271  DT.92409302  DT.100888793  DT.100888806  DT.120878690 
    DT.97826315  DT.100888801  DT.120878687  DT.120878709  DT.91679713  DT.91907694  DT.92456835  DT.95172194 

    24/806 AceView cDNA sequences (see all 806):

    AA257039 AA278398 BQ001743 AA364474 AI934317 BU192932 CR611485 CR592627 
    BU734041 BE780157 BM702082 BQ636751 BU683079 C01944 CA443791 AI955988 
    AA911844 CR593457 AI142543 BF438527 BG540098 AI052425 CA450050 CA429059 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for ARL6IP5    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4
    SP1:              -                 -         
    SP2:                                          
    SP3:              -                           


    ECgene alternative splicing isoforms for ARL6IP5

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARL6IP5 expression in normal human tissues (normalized intensities)      ARL6IP5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTCTAGAATC
    ARL6IP5 Expression
    About this image


    ARL6IP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/28 selected tissues (see all 28) fully expand
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Uterus (Reproductive System)    fully expand to see all 3 entries
             uterus, post-menopause ; glandular cells   
     
     Lung (Respiratory System)    fully expand to see all 3 entries
             lung ; pneumocytes   
     
     Blood (Cardiovascular System)    fully expand to see all 2 entries
             T Helper Cells Thymus
             lung ; macrophages   

    See ARL6IP5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARL6IP5

    SOURCE GeneReport for Unigene clusters: Hs.518060 Hs.745255
        SABiosciences Custom PCR Arrays for ARL6IP5
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL6IP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARL6IP5 gene from 6/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arl6ip51 , 5 ADP-ribosylation factor-like 6 interacting protein more1, 5 87.41(n)1
    90.43(a)1
      6 (44.91 cM)5
    651061  NM_022992.21  NP_075368.11 
     972106895 
    chicken
    (Gallus gallus)
    Aves ARL6IP51 ADP-ribosylation-like factor 6 interacting protein more 76.95(n)
    77.66(a)
      426074  NM_001012605.1  NP_001012623.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARL6IP56
    Uncharacterized protein
    76(a)
    1 ↔ 1
    2(182319021-182337589)
    zebrafish
    (Danio rerio)
    Actinopterygii arl6ip52 ADP-ribosylation factor-like 6 interacting protein more 74.36(n)   386771  AI877919.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Jwa1 Jwa ortholog 53.65(n)
    41.42(a)
      35128  NM_136057.1  NP_609901.4 
    worm
    (Caenorhabditis elegans)
    Secernentea praf-31 Protein PRAF-3 46.46(n)
    37.58(a)
      177637  NM_001027933.1  NP_001023104.1 


    ENSEMBL Gene Tree for ARL6IP5 (if available)
    TreeFam Gene Tree for ARL6IP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARL6IP5 gene
    PRAF22  
    18/70 SIMAP similar genes for ARL6IP5 using alignment to 4 protein entries:     PRAF3_HUMAN (see all proteins) (see all similar genes):
    EIF3G    pp12301    EIF3K    ZNF66    ZNF85    ARIH1
    C12orf76    HDGFRP2    TNNT1    VPS33A    ZNF211    C14orf105
    C1orf143    CALCOCO2    NDC80    SNRPF    TBCB    TMX3

    ARL6IP5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/479 SNPs in ARL6IP5 are shown (see all 479)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1843036641,2
    --69132124(+) TGACCA/CAGATG 1 -- us2k10--------
    rs1904275321,2
    --69132128(+) CAAGAC/TGATTT 1 -- us2k10--------
    rs98347951,2
    C,F,H--69132272(+) TTAACT/GAGTGT 1 -- us2k14Minor allele frequency- G:0.01NS EA 416
    rs1150788751,2
    C,F--69132297(+) AGAAGT/CTTTGA 1 -- us2k11Minor allele frequency- C:0.02NA 120
    rs38663291,2
    C,F--69132341(+) AAAAAA/GAAAAG 1 -- us2k1 trp37Minor allele frequency- G:0.23NA WA EA 366
    rs2004544041,2
    --69132341(+) AAAAA-/GAAAAG 1 -- us2k10--------
    rs1398219331,2
    --69132399(+) AACTCA/GAAATA 1 -- us2k10--------
    rs106176661,2
    C--69132494(+) AAAGTTAG/-TAGAT 1 -- us2k1 tfbs31Minor allele frequency- -:0.50CSA 2
    rs67875691,2
    C,F,A,H--69132554(+) TAGCAA/GACAAG 1 -- us2k1 tfbs3104Minor allele frequency- G:0.25NS EA NA PA EU CA WA CSA 6330
    rs1817328731,2
    C--69132642(+) CTATAC/TATTCC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARL6IP5 (69134090 - 69155239 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ARL6IP5:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv876933CNV Loss21882294
    nsv876934CNV Gain21882294


    Human Gene Mutation Database (HGMD): ARL6IP5
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605709    OMIM disorders: --

    10 diseases for ARL6IP5:    About MalaCards
    alcohol dependence    esophageal squamous cell carcinoma    alcoholism    esophagitis
    squamous cell carcinoma    gastric cancer    myeloid leukemia    hypertension
    leukemia    neuronitis


    ARL6IP5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ARL6IP5
    Human Genome Epidemiology (HuGE) Navigator: ARL6IP5 (5 documents)

    Export disorders for ARL6IP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARL6IP5 gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with ARL6IP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (2000)
    2. Modulation of the neuronal glutamate transporter EAAC1 by the interacting protein GTRAP3-18. (PubMed id 11242046)1, 3, 9 Lin C.I....Rothstein J.D. (2001)
    3. JM4 is a four-transmembrane protein binding to the CCR5 receptor. (PubMed id 15757671)1, 2, 9 Schweneker M.... Moelling K. (2005)
    4. Genomic organization, expression profile, and characterization of the new protein PRA1 domain family, member 2 (PRAF2). (PubMed id 16481131)1, 2, 9 Fo C.S.... Bachmann A.S. (2006)
    5. Functional polymorphisms of JWA gene are associated with risk of bladder cancer. (PubMed id 17479401)1, 4 Li C.P....Zhou J.W. (2007)
    6. Identification and functional characterization of JWA polymorphisms and their association with risk of gastric cancer and esophageal squamous cell carcinoma in a Chinese population. (PubMed id 17479402)1, 4 Tang W.Y....Zhou J.W. (2007)
    7. Single nucleotide polymorphism of the JWA gene is associated with risk of leukemia: a case-control study in a Chinese population. (PubMed id 17479403)1, 4 Zhu Y.J....Zhou J.W. (2007)
    8. [A case-control study on JWA promoter -76G-->C polymorphism and the susceptibility of bladder cancer] (PubMed id 16331563)1, 4 Wu W....Zhou J.W. (2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    10. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10550 HGNC: 16937 AceView: ARL6IP5 Ensembl:ENSG00000144746 euGenes: HUgn10550
    ECgene: ARL6IP5 H-InvDB: ARL6IP5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARL6IP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARL6IP5 gene:
    Search GeneIP for patents involving ARL6IP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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