Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



ARL6IP4 Gene

protein-coding   GIFtS: 52
GCID: GC12P123464

ADP-Ribosylation-Like Factor 6 Interacting Protein 4

  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
ADP-Ribosylation-Like Factor 6 Interacting Protein 41 2     Splicing Factor1
SRp25 Nuclear Protein1 2     SFRS202
HSP-9752 3     SRrp372
SR-152 3     ADP-Ribosylation Factor-Like Protein 6-Interacting Protein 42
SR-252 3     aip-42
SRp252 3     HSVI Binding Protein2
ARL-6-Interacting Protein 42 3     Splicing Factor, Arginine/Serine-Rich 202
HSVI-Binding Protein2 3     Splicing Regulator SRrp382
Arginine/Serine-Rich 201     Aip-43

External Ids:    HGNC: 180761   Entrez Gene: 513292   Ensembl: ENSG000001821967   OMIM: 6076685   UniProtKB: Q66PJ33   
ORGUL members:         

Export aliases for ARL6IP4 gene to outside databases

Previous GC identifers: GC12P122165 GC12P123161 GC12P123273 GC12P121902 GC12P121989 GC12P122030 GC12P120426


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for ARL6IP4 Gene:
ARL6IP4 (ADP-ribosylation-like factor 6 interacting protein 4) is a protein-coding gene.

UniProtKB/Swiss-Prot: AR6P4_HUMAN, Q66PJ3
Function: In case of infection by Herpes simplex virus (HSVI), may act as a splicing inhibitor of HSVI pre-mRNA

Gene Wiki entry for ARL6IP4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the ARL6IP4 gene promoter:
         Sp1   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARL6IP4 promoter sequence
   Search Chromatin IP Primers for ARL6IP4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARL6IP4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

ARL6IP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARL6IP4 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P123464:  view genomic region     (about GC identifiers)

Start:
123,464,607 bp from pter      End:
123,467,460 bp from pter
Size:
2,854 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: AR6P4_HUMAN, Q66PJ3 (See protein sequence)
Recommended Name: ADP-ribosylation factor-like protein 6-interacting protein 4  
Size: 360 amino acids; 38395 Da
Subunit: Interacts with ARL6 (By similarity)
Developmental stage: Expressed only in G1/S phase
Rna editing: Modified_positions=225; Note=Partially edited. In the brain, edited at about 7%
Sequence caution: Sequence=AAF76892.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAF76892.1; Type=Frameshift; Positions=244; Sequence=AAH01958.1; Type=Erroneous initiation;
Sequence=AAH15569.1; Type=Erroneous initiation; Sequence=BAA94744.1; Type=Erroneous initiation;
Secondary accessions: A4UCR8 Q4F966 Q504R8 Q96BI2 Q9NR05 Q9P2R9
Alternative splicing: 6 isoforms:  Q66PJ3-1   Q66PJ3-2   Q66PJ3-3   Q66PJ3-4   Q66PJ3-5   Q66PJ3-6   

Explore the universe of human proteins at neXtProt for ARL6IP4: NX_Q66PJ3

Explore proteomics data for ARL6IP4 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys286, Lys297, Lys322, Lys334
  • Modification sites at PhosphoSitePlus

  • See ARL6IP4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (7 alternative transcripts): 
    NP_001002251.2  NP_001002252.2  NP_001265307.1  NP_001265308.1  NP_001265309.1  NP_057722.3  NP_061164.3  

    ENSEMBL proteins: 
     ENSP00000442718   ENSP00000313422   ENSP00000438969   ENSP00000442200   ENSP00000376230  
     ENSP00000441406   ENSP00000406036   ENSP00000414847   ENSP00000396723   ENSP00000413132  
     ENSP00000396365   ENSP00000391598   ENSP00000350532  

    ARL6IP4 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for ARL6IP4
    OriGene Custom MassSpec
    OriGene Custom Protein Services for ARL6IP4
    GenScript Custom Purified and Recombinant Proteins Services for ARL6IP4
    Novus Biologicals ARL6IP4 Proteins
    Novus Biologicals ARL6IP4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for ARL6IP4

     
    Search eBioscience for Proteins for ARL6IP4 

     
    antibodies-online proteins for ARL6IP4 (9 products) 

     
    antibodies-online peptides for ARL6IP4

    ARL6IP4 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of ARL6IP4
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for ARL6IP4
    Novus Biologicals ARL6IP4 Antibodies
    Abcam antibodies for ARL6IP4
    Cloud-Clone Corp. Antibodies for ARL6IP4
    Search ThermoFisher Antibodies for ARL6IP4
    antibodies-online antibodies for ARL6IP4 (11 products) 

    ARL6IP4 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for ARL6IP4
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for ARL6IP4
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for ARL6IP4
    Cloud-Clone Corp. CLIAs for ARL6IP4
    Search eBioscience for ELISAs for ARL6IP4 
    antibodies-online kits for ARL6IP4 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR019532 Nucl_RNA-splicing_assoc_SR-25

    Graphical View of Domain Structure for InterPro Entry Q66PJ3

    ProtoNet protein and cluster: Q66PJ3

    UniProtKB/Swiss-Prot: AR6P4_HUMAN, Q66PJ3
    Similarity: Belongs to the ARL6IP4 family


    Find genes that share domains with ARL6IP4           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AR6P4_HUMAN, Q66PJ3
    Function: In case of infection by Herpes simplex virus (HSVI), may act as a splicing inhibitor of HSVI pre-mRNA
    Induction: In case of Herpes simplex virus (HSVI)-binding to cells

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with ARL6IP4           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ARL6IP4

    miRNA
    Products:
        
    miRTarBase miRNAs that target ARL6IP4:
    hsa-mir-186-5p (MIRT045254), hsa-mir-92b-3p (MIRT040563), hsa-mir-484 (MIRT042323)

    Block miRNA regulation of human, mouse, rat ARL6IP4 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ARL6IP4:
    hsa-miR-4271
    SwitchGear 3'UTR luciferase reporter plasmidARL6IP4 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ARL6IP4
    Predesigned siRNA for gene silencing in human, mouse, rat ARL6IP4

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for ARL6IP4

    Clone
    Products:
         
    OriGene clones in human, mouse for ARL6IP4 (see all 25)
    OriGene ORF clones in mouse, rat for ARL6IP4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): ARL6IP4 (NM_001002251)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARL6IP4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARL6IP4

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for ARL6IP4
    Browse ESI BIO Cell Lines and PureStem Progenitors for ARL6IP4 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL6IP4


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus TAS10708573

    Find genes that share ontologies with ARL6IP4           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ARL6IP4
    Interactions:

        Search GeneGlobe Interaction Network for ARL6IP4

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    Selected Interacting proteins for ARL6IP4 (Q66PJ31, 3 ENSP000003134224) via UniProtKB, MINT, STRING, and/or I2D (see all 8)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    IKBKGQ9Y6K91, 3, ENSP000003586224EBI-2683099,EBI-81279 I2D: score=1 STRING: ENSP00000358622
    ARL6Q9H0F73, ENSP000003377224I2D: score=3 STRING: ENSP00000337722
    ETS1P149213I2D: score=1 
    FOSP011003I2D: score=1 
    STX11O755583I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008380RNA splicing TAS10708573

    Find genes that share ontologies with ARL6IP4           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ARL6IP4 (AR6P4)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for ARL6IP4 gene (7 alternative transcripts): 
    NM_001002251.2  NM_001002252.2  NM_001278378.1  NM_001278379.1  NM_001278380.1  NM_016638.3  NM_018694.3  

    Unigene Cluster for ARL6IP4:

    ADP-ribosylation-like factor 6 interacting protein 4
    Hs.103561  [show with all ESTs]
    Unigene Representative Sequence: BM907906
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20):
    ENST00000543566 ENST00000315580(uc001ued.3) ENST00000539770 ENST00000542099
    ENST00000392435 ENST00000413381 ENST00000426960 ENST00000453766(uc001uec.3 uc001uee.3 uc001ueg.3 uc001uei.3)
    ENST00000454885(uc009zxt.3) ENST00000539576 ENST00000442210 ENST00000412505
    ENST00000540708 ENST00000536502 ENST00000540382 ENST00000439686 ENST00000392433
    ENST00000456762
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ARL6IP4 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ARL6IP4:
    hsa-miR-4271
    SwitchGear 3'UTR luciferase reporter plasmidARL6IP4 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ARL6IP4
    Predesigned siRNA for gene silencing in human, mouse, rat ARL6IP4
    Clone
    Products:
         
    OriGene clones in human, mouse for ARL6IP4 (see all 25)
    OriGene ORF clones in mouse, rat for ARL6IP4
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 4): ARL6IP4 (NM_001002251)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ARL6IP4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARL6IP4
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for ARL6IP4
    OriGene qSTAR qPCR primer pairs in human, mouse for ARL6IP4
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARL6IP4
      QuantiTect SYBR Green Assays in human, mouse, rat ARL6IP4
      Search QuantiFast Probe-based Assays in human, mouse, rat ARL6IP4

    Additional mRNA sequence: 

    AB035384.1 AF267748.1 AK315759.1 BC001958.1 BC015569.2 BC015909.1 BC094839.1 DQ099385.1 
    EF036485.1 EU624490.1 EU624491.1 

    Selected DOTS entries (see all 38):

    DT.455815  DT.100667623  DT.99996054  DT.97860690  DT.75114915  DT.100667608  DT.100842040  DT.100856913 
    DT.92445018  DT.100807989  DT.100667620  DT.100730966  DT.100667613  DT.100772752  DT.100802813  DT.95087149 
    DT.95087153  DT.100031635  DT.100667621  DT.100848747  DT.121179386  DT.92415351  DT.92445015  DT.97860698 

    5 AceView cDNA sequences:

    NM_016638 NM_001002251 NM_018694 BG109619 NM_001002252 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ARL6IP4 (see all 24)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b · 2c · 2d · 2e ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b · 9c ^ 10a ·
    SP1:                                                  -     -     -     -                       -                                         -                     
    SP2:                                                  -     -     -     -                       -     -                 -     -           -                     
    SP3:                                                  -     -     -     -                 -     -                                         -                     
    SP4:                                                        -     -     -                 -     -                       -     -           -                     
    SP5:                                                        -     -     -                 -     -                                         -                     

    ExUns: 10b · 10c · 10d · 10e · 10f
    SP1:                              
    SP2:                              
    SP3:                              
    SP4:                              
    SP5:                              


    ECgene alternative splicing isoforms for ARL6IP4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    ARL6IP4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCAAGGAGG
    ARL6IP4 Expression
    About this image

    ARL6IP4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ARL6IP4 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.103561
        Custom PCR Arrays for ARL6IP4
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for ARL6IP4
    OriGene qSTAR qPCR primer pairs in human, mouse for ARL6IP4
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARL6IP4
    QuantiTect SYBR Green Assays in human, mouse, rat ARL6IP4
    Search QuantiFast Probe-based Assays in human, mouse, rat ARL6IP4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL6IP4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for ARL6IP4 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arl6ip41 , 5 ADP-ribosylation factor-like 6 interacting protein more1, 5 83.85(n)1
    82.99(a)1
      5 (63.39 cM)5
    651051  NM_144509.21  NP_653092.11 
     1241160895 
    chicken
    (Gallus gallus)
    Aves ARL6IP46
    Gallus gallus ADP-ribosylation-like factor 6 inter...
    62(a)
    1 ↔ 1
    15(5192449-5195746)
    lizard
    (Anolis carolinensis)
    Reptilia ARL6IP46
    ADP-ribosylation-like factor 6 interacting protein...
    58(a)
    1 ↔ 1
    LGb(1986348-2021336)
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.261352 Transcribed sequence with weak similarity to protein more 77.29(n)    BM530019.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG184286
    --
    45(a)
    1 ↔ 1
    3R(19935089-19935732)


    ENSEMBL Gene Tree for ARL6IP4 (if available)
    TreeFam Gene Tree for ARL6IP4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for ARL6IP4 gene
    1 SIMAP similar gene for ARL6IP4 using alignment to 7 protein entries:     AR6P4_HUMAN (see all proteins):
    FLJ00169

    Find genes that share paralogs with ARL6IP4           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for ARL6IP4
    PGOHUM00000258690


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for ARL6IP4 (see all 102)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs128252431,2,,4
    A--123465196(+) GCCGGC/GCAGCC 8 P A mis11Minor allele frequency- G:0.00NA 2
    rs748155191,2
    C,F--123465278(+) CGGCCC/TGCAGG 8 P L mis11Minor allele frequency- T:0.50WA 2
    rs1861576281,2
    --123465437(+) CGGGTA/GCGCAG 4 -- int10--------
    rs1145877841,2
    F--123465456(+) CCTCCG/AGGCAC 4 -- int11Minor allele frequency- A:0.13WA 118
    rs1921749091,2
    --123465607(+) CTAGAA/GCCACC 4 -- int10--------
    rs2009048441,2
    --123465668(+) TCTTCA/GTCGCC 4 -- int10--------
    rs2004242131,2
    C--123465695(+) GCTCAC/GGTCGG 8 H Q mis10--------
    rs1995725701,2
    --123465798(+) GCTCGA/GCCTCC 8 T A mis10--------
    rs2015819351,2
    --123465841(+) TGGGGC/TGGAGG 6 A V int1 mis10--------
    rs79660501,2
    C,F,H--123465877(+) GGAGGC/TGCAGT 4 -- int19Minor allele frequency- T:0.31NS NA CSA WA 1014

    HapMap Linkage Disequilibrium report for ARL6IP4 (123464607 - 123467460 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for ARL6IP4:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv914CNV Insertion18451855
    dgv1497n71CNV Loss21882294
    nsv899577CNV Loss21882294
    nsv455732CNV Loss19166990
    dgv22n68CNV Loss17160897
    nsv899578CNV Loss21882294
    nsv517200CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ARL6IP4
    DNA2.0 Custom Variant and Variant Library Synthesis for ARL6IP4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 607668    OMIM disorders: --


    Find genes that share disorders with ARL6IP4           About GenesLikeMe


    Export disorders for ARL6IP4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for ARL6IP4 gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with ARL6IP4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. An SR-protein induced by HSVI binding to cells functioning as a splicing inhibitor of viral pre-mRNA. (PubMed id 11884129)1, 2, 3 Li Q.... Liu L. (J. Mol. Biol. 2002)
    2. Molecular cloning and expression analysis of a putative nuclear protein, SR-25. (PubMed id 10708573)1, 2, 3 Sasahara K.... Itakura M. (Biochem. Biophys. Res. Commun. 2000)
    3. Genome-wide association analysis identifies 13 new risk loci for schizophrenia. (PubMed id 23974872)1 Ripke S....Sullivan P.F. (Nat. Genet. 2013)
    4. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. A bead-based approach for large-scale identification of in vitro kinase substrates. (PubMed id 22113938)1 Zhang M....Zou H. (Proteomics 2011)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    9. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    10. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 51329 HGNC: 18076 AceView: ARL6IP4 Ensembl:ENSG00000182196 euGenes: HUgn51329
    ECgene: ARL6IP4 H-InvDB: ARL6IP4

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for ARL6IP4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for ARL6IP4 gene:
    Search GeneIP for patents involving ARL6IP4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     EMD Millipore Mono- and Polyclonal Antibodies for the study of ARL6IP4
     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse Small Molecules at EMD Millipore
     Browse Kits and Assays available from EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for ARL6IP4  
     OriGene qPCR primer pairs and template standards for ARL6IP4   OriGene Protein Over-expression Lysate for ARL6IP4  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for ARL6IP4  
     OriGene qSTAR qPCR primer pairs in human, mouse for ARL6IP4   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for ARL6IP4   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for ARL6IP4   OriGene Custom Protein Services for ARL6IP4  

     
     
     Block miRNA regulation of human, mouse, rat ARL6IP4 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing ARL6IP4
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ARL6IP4 Predesigned siRNA for gene silencing in human, mouse, rat ARL6IP4
     Search QuantiFast Probe-based Assays in human, mouse, rat ARL6IP4 QuantiTect SYBR Green Assays in human, mouse, rat ARL6IP4
     Custom PCR Arrays for ARL6IP4 Search Chromatin IP Primers for ARL6IP4
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat ARL6IP4  Search GeneGlobe Interaction Network for ARL6IP4
     Regulatory tfbs in ARL6IP4 promoter
     GenScript Custom Purified and Recombinant Proteins Services for ARL6IP4 GenScript cDNA clones with any tag delivered in your preferred vector for ARL6IP4
     GenScript Custom Assay Services for ARL6IP4 GenScript Custom overexpressing Cell Line Services for ARL6IP4
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for ARL6IP4 (AR6P4)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     ARL6IP4 antibodies
     ARL6IP4 proteins
     ARL6IP4 lysates
     Antibodies for ARL6IP4
     See all of Abcam's Antibodies, Kits and Proteins for ARL6IP4
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for ARL6IP4
     Antibodies for ARL6IP4
     ELISAs for ARL6IP4
     CLIAs for ARL6IP4



     Browse ESI BIO Cell Lines and PureStem Progenitors for ARL6IP4
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL6IP4
     SwitchGear 3'UTR luciferase reporter plasmids for ARL6IP4
     SwitchGear Promoter luciferase reporter plasmids for ARL6IP4
     Search ThermoFisher Antibodies for ARL6IP4
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARL6IP4
     Browse compounds at ApexBio
     Search Addgene for plasmids for ARL6IP4
      Search eBioscience for proteins for ARL6IP4
      Search eBioscience for elisas for ARL6IP4
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for ARL6IP4
     antibodies-online antibodies for ARL6IP4 (11 products)
     antibodies-online kits for ARL6IP4 (8 products)
     antibodies-online peptides for ARL6IP4
     antibodies-online proteins for ARL6IP4 (9 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      ARL6IP4 gene at Home site.
    Version: 3.12.252 27 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4