ARL6 Gene
protein-coding GIFtS: 55
GCID: GC03P097483
|
|
ADP-ribosylation factor-like 6
(Previous symbol: BBS3)
| |
Aliases
for ARL6 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| ADP-Ribosylation Factor-Like 61 2 | | BBS31 2 5 | | Bardet-Biedl Syndrome 3 Protein2 3 | | RP552 5 | | ADP-Ribosylation Factor-Like Protein 62 |
Export aliases for ARL6 gene to outside databasesPrevious GC identifers: GC03P094093 GC03P096787 GC03P098764 GC03P098804 GC03P098966 GC03P094853 |
Summaries
for ARL6 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ARL6:
The protein encoded by this gene belongs to the ARF family of GTP-binding proteins. ARF proteins are importantregulators of cellular traffic and are the founding members of an expanding family of homologous proteins and genomicsequences. They depart from other small GTP-binding proteins by a unique structural device that implements front-backcommunication from the N-terminus to the nucleotide-binding site. Studies of the mouse ortholog of this proteinsuggest an involvement in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been described.(provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ARL6_HUMAN, Q9H0F7Function: Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment ontoplasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membraneproteins to the primary cilia. May regulate cilia assembly and disassembly and subsequent ciliary signaling eventssuch as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization
Gene Wiki entry for ARL6
|
Genomic Views
for ARL6 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ARL6 gene promoter:
HFH-3 C/EBPbeta Pbx1a MEF-2 CUTL1 GATA-1 MEF-2A FOXI1 Cart-1 aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for ARL6
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARL6 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q11.2 Ensembl cytogenetic band: 3q11.2 HGNC cytogenetic band: 3q11.2ARL6 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P097483: view genomic region
(about GC identifiers)
Start:
|
97,483,365 bp from pter |
End:
|
97,519,953 bp from pter |
Size:
|
36,589 bases |
Orientation:
|
plus strand |
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Proteins
for ARL6 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ARL6_HUMAN, Q9H0F7 (See
protein sequence)Recommended Name: ADP-ribosylation factor-like protein 6 Size: 186 amino acids; 21097 Da
Subunit: Interacts with SEC61B, ARL6IP1, ARL6IP2, ARL6IP3, ARL6IP4 ARL6IP5 and ARL6IP6 (By similarity). Interacts(GTP-bound form) with the BBSome a complex that contains BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10
Subcellular location: Cell projection, cilium membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm,cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, cilium basal body. Note=Appears in a pattern of punctaeflanking the microtubule axoneme that likely correspond to small membrane-associated patches. Localizes to theso-called ciliary gate where vesicles carrying ciliary cargo fuse with the membrane
1 PDB 3D structure from  and Proteopedia  for ARL6:2H57 (3D)
Secondary accessions: A8KA93 D3DN31Alternative splicing: 2 isoforms: Q9H0F7-1 Q9H0F7-2 (Gene prediction based on EST data)Explore the universe of human proteins at neXtProt for ARL6: NX_Q9H0F7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9H0F7
ARL6 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_115522.1 NP_816931.1
ENSEMBL proteins: ENSP00000418057 ENSP00000419619 ENSP00000418740 ENSP00000419934 ENSP00000337722 ENSP00000377756
Human Recombinant Protein Products:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
ARL6 for ontologies About GeneDecksing
ARL6 Antibody Products:
Assay Products for ARL6: |
Protein
Domains /
Families
for ARL6 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ARL6 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9H0F7ProtoNet protein and cluster: Q9H0F7 1 Blocks protein family: IPB006688 ADP-ribosylation factor
UniProtKB/Swiss-Prot: ARL6_HUMAN, Q9H0F7Similarity: Belongs to the small GTPase superfamily. Arf family |
Function
for ARL6 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ARL6_HUMAN, Q9H0F7Function: Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment ontoplasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membraneproteins to the primary cilia. May regulate cilia assembly and disassembly and subsequent ciliary signaling eventssuch as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARL6 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARL6 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ARL6 (NM_006407) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARL6 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARL6 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL6 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
ARL6 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for ARL6:
Animal Models:
Mouse knock-out Arl6tm2Vcs for ARL6
10 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Arl6):
ARL6 for phenotypes About GeneDecksing
|
Pathways & Interactions
for ARL6 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARL6
STRING Interaction
Network Preview (showing 5 interactants - click image to see 15)
5/17 Interacting proteins for ARL6 (Q9H0F71, 3 ENSP000003377224) via UniProtKB, MINT, STRING, and/or I2D (see all 17)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006612 | protein targeting to membrane |
ISS | -- | | GO:0007264 | small GTPase mediated signal transduction |
IEA | -- | | GO:0007368 | determination of left/right symmetry |
ISS | -- | | GO:0007601 | visual perception |
IEA | -- | | GO:0016055 | Wnt receptor signaling pathway |
IMP | -- |
ARL6 for ontologies About GeneDecksing
|
Drugs & Compounds
for ARL6 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for ARL6
Search CenterWatch for drugs/clinical trials and news about ARL6
|
Transcripts
for ARL6 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ARL6 gene (2 alternative transcripts): NM_032146.3 NM_177976.1 Unigene Cluster for ARL6: ADP-ribosylation factor-like 6 Hs.373801 [show with all ESTs]Unigene Representative Sequence: BC0242398 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000493990(uc003drw.3) ENST00000463745(uc010hoy.3) ENST00000462412
ENST00000496713 ENST00000476753 ENST00000494363 ENST00000335979(uc003dru.3)
ENST00000394206(uc003drv.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARL6 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARL6 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ARL6 (NM_006407) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ARL6 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARL6 |
Additional cDNA sequence: AK292958.1 AK310829.1 AK311281.1 AL136815.1 BC024239.2 6 DOTS entries: DT.120855570 DT.100020319 DT.40316749 DT.100751594 DT.120855578 DT.40210483 24/57 AceView cDNA sequences (see all 57): NM_032146 NM_177976 BX280713 BM464340 BC024239 AL136815 BM982145 BI914103 BM705017 BG433067 AI936661 BQ441226 AI382134 AA732878 AA904677 BG722744 BQ429563 AA058979 BU607306 AI762435 BI918227 AA284208 AI659604 CD250432
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for ARL6 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7a | · | 7b | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | - | | | | |
| SP2: | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | |
ECgene alternative splicing isoforms for ARL6
|
Expression
for ARL6 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ARL6 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCATTAAAA
About this image
See ARL6 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ARL6
SOURCE GeneReport for Unigene cluster: Hs.373801
SABiosciences Expression via Pathway-Focused PCR Array including ARL6:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARL6
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ARL6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARL6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARL6 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL6 |
Orthologs
for ARL6 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ARL6 gene from 5/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
ARL66 |
-- |
88(a) |
1 ↔ 1 |
3(164160423-164171605) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.248122 |
Xenopus laevis transcribed sequence with moderate similarity more |
79.15(n) |
|
CA971706.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.186382 |
Transcribed sequence with moderate similarity to protein more |
76.98(n) |
|
BQ481315.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG77351 |
CG7735 |
56.41(n)
55.49(a) |
|
37236 NM_137577.2 NP_611421.1 |
worm
(Caenorhabditis elegans) |
Secernentea |
arl-61 |
Protein ARL-6 |
50.83(n)
44.75(a) |
|
183311 NM_065592.1 NP_497993.1 |
ENSEMBL Gene Tree for ARL6 (if available)
TreeFam Gene Tree for ARL6 (if available) |
Paralogs
for ARL6 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for ARL6 gene
- ARL5B2 ARL162 ARL5C2 ARL5A2 ARL12
18/30 SIMAP similar genes for ARL6 using alignment to 3 protein entries: ARL6_HUMAN (see all proteins)
(see all similar genes):ARF1 ARL8A ARL8B ARL17A ARL17B ARF4
ARL3 ARF3 ARF5 ARL1 ARL14 TRIM23
SAR1B ARL2 ARF6 ARL11 ARL5B ARL5A
ARL6 for paralogs About GeneDecksing
|
Genomic Variants
for ARL6 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ARL6 (97483365 - 97519953 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ARL6: --
Human Gene Mutation Database (HGMD): ARL6
Locus Specific Mutation Databases (LSDB): ARL6
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARL6 |
|
Disorders
/ Diseases
for ARL6 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ARL6 for disorders About GeneDecksing
OMIM gene information: 608845
OMIM disorders: 209900 613575
UniProtKB/Swiss-Prot: ARL6_HUMAN, Q9H0F7
Defects in ARL6 are a cause of Bardet-Biedl syndrome type 3 (BBS3) [MIM:209900]. Bardet-Biedl syndrome (BBS)is a genetically heterogeneous disorder characterized by usually severe pigmentary retinopathy, early onset obesity,polydactyly, hypogenitalism, renal malformation and mental retardation. Secondary features include diabetes mellitus,hypertension and congenital heart disease Defects in ARL6 are the cause of retinitis pigmentosa type 55 (RP55) [MIM:613575]. RP55 is a retinal dystrophybelonging to the group of pigmentary retinopathies. Retinitis pigmentosa is characterized by retinal pigment depositsvisible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of conephotoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As theircondition progresses, they lose their far peripheral visual field and eventually central vision as well
18  diseases for ARL6: About MalaCardsbardet-biedl syndrome bardet-biedl syndrome 3 bardet-biedl syndrome 1 bardet-biedl syndrome 1, modifier of
pigmentary retinopathy retinitis pigmentosa fundus dystrophy intellectual disability
meckel syndrome retinal degeneration retinitis polydactyly
azoospermia retinal disease blindness obesity
malaria neuronitis
2 diseases from the University of Copenhagen DISEASES database for ARL6:Polydactyly Fundus dystrophy GeneTests: ARL6
Bardet-Biedl Syndrome
Human Genome Epidemiology (HuGE) Navigator: ARL6 (5 documents)
Export disorders for ARL6 gene to outside databases
|
Publications
for ARL6 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ARL6 gene, integrated from 9 sources (see all 34):
(articles sorted by number of sources associating them with ARL6) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Comparative genomic analysis identifies an ADP-ribosylation factor- like gene as the cause of Bardet-Biedl Syndrome (BBS3). (PubMed id 15258860)1, 2, 3, 9 Chiang A.P....Sheffield V.C. (2004)
- Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. (PubMed id 15314642)1, 2, 3 Fan Y.... Leroux M.R. (2004)
- Functional analysis of BBS3 A89V that results in non- syndromic retinal degeneration. (PubMed id 21282186)1, 3 Pretorius P.R....Slusarski D.C. (2011)
- Bardet-Biedl syndrome-associated small GTPase ARL6 (B BS3) functions at or near the ciliary gate and modulates Wnt signaling. (PubMed id 20207729)1, 2 Wiens C.J....Leroux M.R. (2010)
- Identification and functional analysis of the vision- specific BBS3 (ARL6) long isoform. (PubMed id 20333246)1, 2 Pretorius P.R....Slusarski D.C. (2010)
- Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome. (PubMed id 19236846)1, 2 Kobayashi T....Katada T. (2009)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for ARL6 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ARL6 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ARL6 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ARL6 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for ARL6 | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ARL6 |
|
| | |
About This Section
| Patent Information for ARL6 gene:
Search GeneIP for patents involving ARL6
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for ARL6 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ARL6 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ARL6 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ARL6 | | | OriGene Protein Over-expression Lysate for ARL6 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ARL6 | | OriGene 3'-UTR Clone for ARL6 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ARL6 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ARL6 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for ARL6 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ARL6 | | OriGene Custom Protein Services for ARL6 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ARL6 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ARL6 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARL6 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ARL6 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARL6 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ARL6 |
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| | | | Search Tocris compounds for ARL6 |
| |  |  |  |  | | | | | | Recombinant Protein for ARL6 |
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 | | | ARL6 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL6 |
|  |  |  | | | | ThermoFisher Antibodies for ARL6 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ARL6 |
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