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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARL4A Gene

protein-coding   GIFtS: 51
GCID: GC07P012726

ADP-Ribosylation Factor-Like 4A

(Previous name: ADP-ribosylation factor-like 4)
(Previous symbol: ARL4)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
ADP-Ribosylation Factor-Like 4A1 2
ARL41 2 3 5
ADP-Ribosylation Factor-Like 41 2
ADP-Ribosylation Factor-Like Protein 4A2

External Ids:    HGNC: 6951   Entrez Gene: 101242   Ensembl: ENSG000001226447   OMIM: 6047865   UniProtKB: P406173   

Export aliases for ARL4A gene to outside databases

Previous GC identifers: GC07P012471 GC07P012499 GC07P012693


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARL4A Gene:
ADP-ribosylation factor-like 4A is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4A
is similar to ARL4C and ARL4D and each has a nuclear localization signal and an unusually high guaninine
nucleotide exchange rate. ARL4A is located in both the nuclear and extranuclear cell compartments. Multiple
transcript variants encoding the same protein have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for ARL4A Gene: 
ARL4A (ADP-ribosylation factor-like 4A) is a protein-coding gene. Diseases associated with ARL4A include cholera. GO annotations related to this gene include protein binding and GTP binding. An important paralog of this gene is ARF4.

UniProtKB/Swiss-Prot: ARL4A_HUMAN, P40617
Function: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and
the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins
(GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit.
Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form

Gene Wiki entry for ARL4A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARL4A gene promoter:
         Oct-B1   oct-B2   oct-B3   POU2F1   POU2F1a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ARL4A promoter sequence
   Search SABiosciences Chromatin IP Primers for ARL4A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARL4A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21.3   Ensembl cytogenetic band:  7p21.3   HGNC cytogenetic band: 7p21.3

ARL4A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARL4A gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P012726:  view genomic region     (about GC identifiers)

Start:
12,726,452 bp from pter      End:
12,730,559 bp from pter
Size:
4,108 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 12,777,588-12,781,695     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: ARL4A_HUMAN, P40617 (See protein sequence)
Recommended Name: ADP-ribosylation factor-like protein 4A  
Size: 200 amino acids; 22615 Da
Subunit: Interacts with CYTH2. Interacts with KPNA2; the interaction is direct. Does not interacts with ARL4A
Subcellular location: Cell membrane. Cytoplasm. Nucleus, nucleolus. Note=Localization in the nucleolus is
dependent by nucleotide binding
Secondary accessions: A4D119 P80418 Q49AF5

Explore the universe of human proteins at neXtProt for ARL4A: NX_P40617

Explore proteomics data for ARL4A at MOPED 

Post-translational modifications:

  • UniProtKB: Myristoylated
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P40617

  • ARL4A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    ARL4A Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001032241.1  NP_001182325.1  NP_005729.1  NP_997625.1  

    ENSEMBL proteins: 
     ENSP00000379897   ENSP00000349250   ENSP00000379899   ENSP00000397651   ENSP00000385236  
     ENSP00000379898  

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    Browse Proteins at Cloud-Clone Corp. 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA10980193
    GO:0005730nucleolus IDA10980193
    GO:0005737cytoplasm IEA--
    GO:0005886plasma membrane IDA17398095

    ARL4A for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ARL: ADP-ribosylation factors-like

    5 InterPro protein domains:
     IPR027417 P-loop_NTPase
     IPR006689 Small_GTPase_ARF/SAR
     IPR024156 Small_GTPase_ARF
     IPR005225 Small_GTP-bd_dom
     IPR001806 Small_GTPase

    Graphical View of Domain Structure for InterPro Entry P40617

    ProtoNet protein and cluster: P40617

    1 Blocks protein domain: IPB006688 ADP-ribosylation factor

    UniProtKB/Swiss-Prot: ARL4A_HUMAN, P40617
    Similarity: Belongs to the small GTPase superfamily. Arf family


    ARL4A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ARL4A_HUMAN, P40617
    Function: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and
    the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins
    (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit.
    Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in GDP-bound form

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity ----
    GO:0005515protein binding IPI10980193
    GO:0005525GTP binding IDA10980193
         
    ARL4A for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ARL4A:
     Decreased melanin production  Synthetic lethal with Ras 

         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Arl4a):
     adipose tissue  endocrine/exocrine gland  homeostasis/metabolism  reproductive system 

    ARL4A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Arl4atm1Asch for ARL4A

       inGenious Targeting Laboratory - Custom generated mouse model solutions for ARL4A 
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    SwitchGear 3'UTR luciferase reporter plasmidARL4A 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARL4A

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for ARL4A (P406173 ENSP000003492504) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KPNA2P522923, ENSP000003324554I2D: score=2 STRING: ENSP00000332455
    NKD1Q969G93I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process ----
    GO:0006886intracellular protein transport ----
    GO:0007165signal transduction ----
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0015031protein transport ----

    ARL4A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARL4A

    Search CenterWatch for drugs/clinical trials and news about ARL4A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARL4A gene (4 alternative transcripts): 
    NM_001037164.2  NM_001195396.1  NM_005738.4  NM_212460.3  

    Unigene Cluster for ARL4A:

    ADP-ribosylation factor-like 4A
    Hs.245540  [show with all ESTs]
    Unigene Representative Sequence: NM_005738
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396662(uc003ssq.3) ENST00000356797 ENST00000396664 ENST00000439721
    ENST00000404894 ENST00000396663(uc003ssp.3 uc021zzq.1 uc003sss.3)

    miRNA
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    hsa-miR-579 hsa-miR-520e hsa-miR-520f hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-3653 hsa-miR-138-2*
    SwitchGear 3'UTR luciferase reporter plasmidARL4A 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF493890.1 AK313233.1 BC001111.2 BC003027.1 U73960.1 

    6 DOTS entries:

    DT.113752  DT.121080158  DT.100792805  DT.100028464  DT.100028466  DT.121255341 

    24/206 AceView cDNA sequences (see all 206):

    BM979023 AI151110 AV715591 AU137799 NM_212460 CA313380 AI313467 BU784677 
    NM_005738 BM550177 AW083580 CA431200 CD367268 AA744367 CA311435 CA309708 
    AI224585 BG575521 BM832972 BQ434200 AA055537 CR598643 BE272886 AW780345 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARL4A expression in normal human tissues (normalized intensities)      ARL4A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATATGATCAT
    ARL4A Expression
    About this image


    ARL4A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/9 selected tissues (see all 9) fully expand
     
     Testis (Reproductive System)    fully expand to see all 3 entries
             Leydig Cells Testis Interstitium
             Testis Interstitium
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Oligodendrocyte Precursor Cells Forebrain White Matter
             Midbrain dopaminergic-like neurons ( Generation of midbrain dopaminergic, forebrain...
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+TGFbeta3+GDF5-induced SK11 cells
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+TGFbeta3+GDF5-induced SK11 cells
     
     Adipose (Muscoskeletal System)    fully expand to see all 2 entries
             Body Subcutaneous White Adipose

    See ARL4A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARL4A

    SOURCE GeneReport for Unigene cluster: Hs.245540
        SABiosciences Custom PCR Arrays for ARL4A
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ARL4A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARL4A gene from 7/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arl4a1 , 5 ADP-ribosylation factor-like 4A1, 5 92.5(n)1
    99.5(a)1
      12 (18.06 cM)5
    118611  NM_001039515.11  NP_001034604.11 
     400054475 
    chicken
    (Gallus gallus)
    Aves ARL4A1 ADP-ribosylation factor-like 4A 80.83(n)
    96.5(a)
      420589  XM_418690.2  XP_418690.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARL4A6
    Uncharacterized protein
    95(a)
    1 ↔ 1
    6(25852470-25857454)
    African clawed frog
    (Xenopus laevis)
    Amphibia AY009369.12   -- 79.28(n)    AY009369.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc778002 hypothetical protein MGC77800 76.66(n)   393834  BC050164.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG22191 CG2219 58.03(n)
    56.82(a)
      43771  NM_143648.2  NP_651905.1 
    worm
    (Caenorhabditis elegans)
    Secernentea arc-16
    E3 ubiquitin-protein ligase arc-1
    10(a)
    possible ortholog
    II(9674975-9677205)


    ENSEMBL Gene Tree for ARL4A (if available)
    TreeFam Gene Tree for ARL4A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARL4A gene
    ARF42  ARL112  ARF52  ARF12  ARL142  ARL4D2  ARF32  ARF62  
    ARL4C2  ARL8A2  TRIM232  ARL8B2  
    18/28 SIMAP similar genes for ARL4A using alignment to 2 protein entries:     ARL4A_HUMAN (see all proteins) (see all similar genes):
    ARL4C    ARL7    ARL4D    ARF4    ARF5    ARF3
    ARL14    ARL8A    ARF1    ARF6    ARL8B    ARL1
    ARL11    ARL5A    ARL5B    TRIM23    ARL2    SAR1A

    ARL4A for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for ARL4A
    PGOHUM00000251260 PGOHUM00000251271 PGOHUM00000237557 PGOHUM00000250217 PGOHUM00000263316


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/160 SNPs in ARL4A are shown (see all 160)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0243674
    ----see VAR_0243672 R K mis40--------
    rs1839776491,2
    C--12724463(+) AACCTC/GCGCCT 2 -- us2k10--------
    rs1434620191,2
    --12724464(+) ACCTCC/TGCCTC 2 -- us2k10--------
    rs20336031,2
    C,F,A--12724470(-) GCCCGG/AGAGGC 2 -- us2k16Minor allele frequency- A:0.17NA CSA WA EA 364
    rs1467368031,2
    --12724582(+) CCCACG/TTTGGC 2 -- us2k10--------
    rs1883106861,2
    --12724651(+) AGTCAC/TAAAAG 2 -- us2k10--------
    rs1392962801,2
    --12724680(+) ATAGCG/TGTCTT 2 -- us2k10--------
    rs1150178301,2
    C,F--12724693(+) GAAAAA/GCTAGG 2 -- us2k11Minor allele frequency- G:0.03WA 118
    rs20336021,2
    C,F,A,H--12724698(-) AATATC/GCTAGT 2 -- us2k123Minor allele frequency- G:0.15NA EA NS CSA WA 2596
    rs1440692721,2
    --12724699(+) CTAGGA/GTATTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARL4A (12726452 - 12730559 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ARL4A:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv830907CNV Loss17160897
    nsv830908CNV Gain17160897

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 604786    OMIM disorders: --

    2 diseases for ARL4A:    About MalaCards
    cholera    


    ARL4A for disorders           About GeneDecksing

    Genetic Association Database (GAD): ARL4A

    Export disorders for ARL4A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARL4A gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with ARL4A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The Arl4 family of small G proteins can recruit the cytohesin Arf6 exchange factors to the plasma membrane. (PubMed id 17398095)1, 2 Hofmann I....Munro S. (2007)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    4. ARL4, an ARF-like protein that is developmentally regulated and localized to nuclei and nucleoli. (PubMed id 10980193)1, 2 Lin C.Y....Lee F.J. (2000)
    5. ADP-ribosylation factor (ARF)-like 4, 6, and 7 represent a subgroup of the ARF family characterization by rapid nucleotide exchange and a nuclear localization signal. (PubMed id 10462049)1, 2 Jacobs S....Joost H.-G. (1999)
    6. ARL4A acts with GCC185 to modulate Golgi complex organ ization. (PubMed id 22159419)1 Lin Y.C....Lee F.J. (2011)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. The Arf family GTPase Arl4A complexes with ELMO prote ins to promote actin cytoskeleton remodeling and reveals a versatile Ras-bindin g domain in the ELMO proteins family. (PubMed id 21930703)1 Patel M....CA'tAc J.F. (2011)
    9. GWAS for discovery and replication of genetic loci as sociated with sudden cardiac arrest in patients with coronary artery disease. (PubMed id 21658281)4 Aouizerat B.E....Tseng Z.H. (2011)
    10. Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation. (PubMed id 18240926)1 Chi J.H....Parsa A.T. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10124 HGNC: 695 AceView: ARL4A Ensembl:ENSG00000122644 euGenes: HUgn10124
    ECgene: ARL4A H-InvDB: ARL4A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARL4A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARL4A gene:
    Search GeneIP for patents involving ARL4A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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