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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARL2BP Gene

protein-coding   GIFtS: 48
GCID: GC16P057279

ADP-ribosylation factor-like 2 binding protein

 Explore 5 diseases affiliated with
ARL2BP via our new
 Human Malady Compendium 
Biological research products
for ARL2BP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ADP-Ribosylation Factor-Like 2 Binding Protein1 2     ADP-Ribosylation Factor-Like Protein 2-Binding Protein2
BART1 2 3     Arf-Like 2 Binding Protein BART12
BART11 2 3     Binder Of Arl Two2
Binder Of ARF2 Protein 12 3     Binder Of Arl22
ARF-Like 2-Binding Protein2 3     

External Ids:    HGNC: 171461   Entrez Gene: 235682   Ensembl: ENSG000001029317   UniProtKB: Q9Y2Y03   

Export aliases for ARL2BP gene to outside databases

Previous GC identifers: GC00U913737 GC16P057055 GC16P055836 GC16P043148


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARL2BP:
ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of
RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with
ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon
activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the
first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating
protein activity. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: AR2BP_HUMAN, Q9Y2Y0
Function: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of
STAT3. May play a role as an effector of ARL2




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARL2BP gene promoter:
         Pbx1a   AML1a   MyoD   MIF-1   Tal-1beta   POU3F2   YY1   HFH-1   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARL2BP promoter sequence
   Search SABiosciences Chromatin IP Primers for ARL2BP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARL2BP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q13   Ensembl cytogenetic band:  16q13   HGNC cytogenetic band: 16q13

ARL2BP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARL2BP gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P057279:  view genomic region     (about GC identifiers)

Start:
57,279,010 bp from pter      End:
57,287,545 bp from pter
Size:
8,536 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AR2BP_HUMAN, Q9Y2Y0 (See protein sequence)
Recommended Name: ADP-ribosylation factor-like protein 2-binding protein  
Size: 163 amino acids; 18822 Da
Subunit: Found in a complex with ARL2BP, ARL2 and SLC25A6. Found in a complex with ARL2, ARL2BP and SLC25A4. Interacts
with STAT2, STAT3 and STAT4. Interacts with GTP bound ARL2 and ARL3; the complex ARL2-ARL2BP as well as ARL2BP alone,
binds to ANT1. Interacts with STAT3; interaction is enhanced with ARL2
Subcellular location: Cytoplasm. Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, centrosome. Nucleus.
Cytoplasm, cytoskeleton, spindle. Note=The complex formed with ARL2BP, ARL2 and SLC25A4 is expressed in mitochondria
(By similarity). Detected in the midbody matrix. Not detected in the Golgi, nucleus and on the mitotic spindle.
Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules
3 PDB 3D structures from and Proteopedia for ARL2BP:
2K9A (3D)        3DOE (3D)        3DOF (3D)    
Secondary accessions: B3KQJ5 Q504R0
Alternative splicing: 2 isoforms:  Q9Y2Y0-1   Q9Y2Y0-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ARL2BP: NX_Q9Y2Y0

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9Y2Y0

  • ARL2BP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036238.1  
    ENSEMBL proteins: 
     ENSP00000219204   ENSP00000457465   ENSP00000454237  

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    Uscn Proteins for ARL2BP

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005758mitochondrial intermembrane space IDA11809823
    GO:0005813centrosome IDA16525022
    GO:0005819spindle IEA--
    GO:0030496midbody IDA16525022


    ARL2BP for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ARL2BP for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR023379 ARF-like_2-bdp_dom

    Graphical View of Domain Structure for InterPro Entry Q9Y2Y0

    ProtoNet protein and cluster: Q9Y2Y0

    UniProtKB/Swiss-Prot: AR2BP_HUMAN, Q9Y2Y0
    Similarity: Belongs to the ARL2BP family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: AR2BP_HUMAN, Q9Y2Y0
    Function: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of
    STAT3. May play a role as an effector of ARL2

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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003713transcription coactivator activity IMP18234692
    GO:0005083small GTPase regulator activity TAS10488091
    GO:0005515protein binding IPI19368893


    ARL2BP for ontologies           About GeneDecksing



    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ARL2BP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    5/6 Interacting proteins for ARL2BP (Q9Y2Y03 ENSP000002192044) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARL2P364043, ENSP000002467474I2D: score=3 STRING: ENSP00000246747
    ARL3P364053, ENSP000002607464I2D: score=3 STRING: ENSP00000260746
    RAC1P630003, ENSP000003484614I2D: score=3 STRING: ENSP00000348461
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    CAMK2DENSP000003397404STRING: ENSP00000339740
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction TAS10488091
    GO:0042517positive regulation of tyrosine phosphorylation of Stat3 protein IMP18234692
    GO:0051457maintenance of protein location in nucleus IMP18234692


    ARL2BP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for ARL2BP

    1 HMDB Compound for ARL2BP    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    Search CenterWatch for drugs/clinical trials and news about ARL2BP / AR2BP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARL2BP gene: 
    NM_012106.3  

    Unigene Cluster for ARL2BP:

    ADP-ribosylation factor-like 2 binding protein
    Hs.632873  [show with all ESTs]
    Unigene Representative Sequence: NM_012106
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000219204(uc010ccy.1 uc010vhl.2 uc002elf.1) ENST00000565794
    ENST00000562023 ENST00000563234

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    hsa-miR-3163 hsa-miR-485-5p hsa-miR-429 hsa-miR-374b hsa-miR-496 hsa-miR-374a hsa-miR-548aa hsa-miR-200c
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    Additional cDNA sequence: 

    AF126062.1 AK075050.1 AK298758.1 AK311018.1 BC003087.1 BC094878.1 

    14 DOTS entries:

    DT.456284  DT.87013042  DT.100833365  DT.95115126  DT.120662725  DT.100717344  DT.100717345  DT.95115162 
    DT.100029469  DT.100761310  DT.120662735  DT.92436200  DT.97861981  DT.97780032 

    24/348 AceView cDNA sequences (see all 348):

    CA848854 AA284158 BP345932 BC003087 AI755157 AW273090 AA100215 AU280281 
    CB124813 CF130653 AA447844 BF940026 BG236444 CR597343 BQ899111 AW591051 
    AI740768 AA291237 AA309112 BM312227 AI280937 CR605296 CB136331 AI304416 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for ARL2BP    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c ^ 5a · 5b ^ 6a · 6b · 6c · 6d · 6e · 6f
    SP1:                    -                                                                                       
    SP2:                    -                                                     -                                 
    SP3:                    -                                   -                                                   
    SP4:                    -           -     -     -                                                               
    SP5:                                      -     -     -     -     -                                             


    ECgene alternative splicing isoforms for ARL2BP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARL2BP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGTAAAACTT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    ARL2BP expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Head MesenchymeBranchial Arch 1Paraxial Mesoderm CellsBone, Skeletal Muscle
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See ARL2BP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARL2BP

    SOURCE GeneReport for Unigene cluster: Hs.632873

    UniProtKB/Swiss-Prot: AR2BP_HUMAN, Q9Y2Y0
    Tissue specificity: Ubiquitous

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for ARL2BP gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Arl2bp1 , 5 ADP-ribosylation factor-like 2 binding protein1, 5 88.14(n)1
    95.71(a)1
      8 (46.65 cM)5
    1075661  NM_024191.11  NP_077153.11 
     946667555 
    chicken
    (Gallus gallus)
    Aves ARL2BP1 ADP-ribosylation factor-like 2 binding protein 76.54(n)
    78.95(a)
      426495  NM_001007970.1  NP_001007971.1 
    lizard
    (Anolis carolinensis)
    Reptilia ARL2BP6
    --
    80(a)
    1 ↔ 1
    GL343677.1(222958-229264)
    zebrafish
    (Danio rerio)
    Actinopterygii arl2bp1 ADP-ribosylation factor-like 2 binding protein 69.89(n)
    70.32(a)
      393976  NM_201001.1  NP_957295.1 
    mosquito
    (Anopheles gambiae)
    Insecta AgaP_AGAP0129171 AGAP012917-PA 55.81(n)
    45.74(a)
      1267767  XM_306324.3  XP_306324.3 


    ENSEMBL Gene Tree for ARL2BP (if available)
    TreeFam Gene Tree for ARL2BP (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARL2BP gene

    ARL2BP for paralogs           About GeneDecksing


    5/11 Pseudogenes.org Pseudogenes for ARL2BP (see all 11)
    PGOHUM00000239787 PGOHUM00000248568 PGOHUM00000246916 PGOHUM00000237111 PGOHUM00000237189


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/183 NCBI SNPs in ARL2BP are shown (see all 183    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs8895561,2
    C,F,A,H,--57277196(+) CTTTTA/TAAATG 1 -- us2k114Minor allele frequency- T:0.01NS EA NA WA CSA 554
    rs1486622721,2
    --57277222(+) GTGCTA/GAACAG 1 -- us2k10--------
    rs1815379271,2
    --57277254(+) CCTGAC/GCGGGT 1 -- us2k10--------
    rs1874606671,2
    --57277401(+) TGGTGA/GCACGC 1 -- us2k10--------
    rs1919109771,2
    --57277561(+) AGTGGC/TTCACG 1 -- us2k10--------
    rs1823971091,2
    --57277585(+) CACTTC/TGGGAG 1 -- us2k10--------
    rs1510574671,2
    --57277618(+) AGGTCA/GGGAGT 1 -- us2k10--------
    rs20083171,2
    C,F,H,--57277748(+) TTGAAC/ACCGGT 1 -- us2k16Minor allele frequency- A:0.18NA WA CSA 11
    rs1867841261,2
    --57277821(+) AACTCA/CATCTC 1 -- us2k10--------
    rs1904083481,2
    --57277828(+) TCTCAA/GTAAAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for ARL2BP (57279010 - 57287545 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for ARL2BP
         1 Indel: 60209

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ARL2BP for disorders           About GeneDecksing

    5 diseases for ARL2BP:    About MalaCards
    retinitis pigmentosa-2    retinitis pigmentosa    retinitis    pancreatic cancer
    pancreatitis


    Export disorders for ARL2BP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARL2BP gene, integrated from 9 sources (see all 20):
    (articles sorted by number of sources associating them with ARL2BP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The Structure of Binder of Arl2 (BART) Reveals a Novel G Protein Binding Domain: IMPLICATIONS FOR FUNCTION. (PubMed id 18981177)1, 2, 3 Bailey L.K....Mott H.R. (2009)
    2. The ARF-like 2 (ARL2)-binding protein, BART. Purification, cloning, and initial characterization. (PubMed id 10488091)1, 2, 3 Sharer J.D. and Kahn R.A. (1999)
    3. Crystal structure of the ARL2-GTP-BART complex reveal s a novel recognition and binding mode of small GTPase with effector. (PubMed id 19368893)1, 2 Zhang T....Ding J. (2009)
    4. BART is essential for nuclear retention of STAT3. (PubMed id 18234692)1, 2 Muromoto R....Matsuda T. (2008)
    5. Arl2 and Arl3 regulate different microtubule-dependent processes. (PubMed id 16525022)1, 2 Zhou C.... Kahn R.A. (2006)
    6. Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C. (PubMed id 11847227)1, 2 Bartolini F....Cowan N.J. (2002)
    7. ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter. (PubMed id 11809823)1, 2 Sharer J.D.... Kahn R.A. (2002)
    8. ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins. (PubMed id 11303027)1, 2 Van Valkenburgh H.... Kahn R.A. (2001)
    9. BART inhibits pancreatic cancer cell invasion by Rac1 inactivation through direct binding to active Rac1. (PubMed id 22745590)1 Taniuchi K....Saibara T. (2012)
    10. BART inhibits pancreatic cancer cell invasion by PKCa inactivation through binding to ANX7. (PubMed id 22532868)1 Taniuchi K....Saibara T. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23568 HGNC: 17146 AceView: ARL2BP Ensembl:ENSG00000102931 euGenes: HUgn23568
    ECgene: ARL2BP H-InvDB: ARL2BP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARL2BP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARL2BP gene:
    Search GeneIP for patents involving ARL2BP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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