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Aliases for ARL2-SNX15 Gene

Subcategory (RNA class) for ARL2-SNX15 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for ARL2-SNX15 Gene

  • ARL2-SNX15 Readthrough (NMD Candidate) 2 3 5

External Ids for ARL2-SNX15 Gene

Previous GeneCards Identifiers for ARL2-SNX15 Gene

  • GC11U901787
  • GC11P064783
  • GC11P064784

Summaries for ARL2-SNX15 Gene

Entrez Gene Summary for ARL2-SNX15 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring ADP-ribosylation factor-like 2 (ARL2) and sorting nexin 15 (SNX15) genes on chromosome 11. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Dec 2010]

GeneCards Summary for ARL2-SNX15 Gene

ARL2-SNX15 (ARL2-SNX15 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include GTP binding and signal transducer activity. An important paralog of this gene is ARL2.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ARL2-SNX15 Gene

Genomics for ARL2-SNX15 Gene

Regulatory Elements for ARL2-SNX15 Gene

Enhancers for ARL2-SNX15 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G065012 1.1 ENCODE 0.7 +0.1 97 2.7 HDGF PKNOX1 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B SPDYC ARL2 ARL2-SNX15 MIR6879
GH11G065006 1.1 Ensembl ENCODE 0.4 -6.7 -6656 2.4 TBP SIN3A RAD21 RFX5 EGR1 SCRT2 RCOR1 FOS DEK USF2 ARL2 EEF1A1P18 EHBP1L1 ARL2-SNX15 BATF2
GH11G064996 1.1 ENCODE 0.4 -15.9 -15947 3.9 HDGF MLX CREB3L1 ARID4B SIN3A DMAP1 FEZF1 ZNF2 YY1 CBX5 TRMT112 EHBP1L1 SPDYC EEF1A1P18 SAC3D1 SLC22A20 BATF2 ARL2 ARL2-SNX15
GH11G065002 0.6 ENCODE 0.4 -11.1 -11135 1.1 SMAD5 MIER1 POLR2A CEBPA CEBPB MIER2 REST ZBTB26 EHBP1L1 EEF1A1P18 BATF2 ARL2-SNX15 ARL2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around ARL2-SNX15 on UCSC Golden Path with GeneCards custom track

Promoters for ARL2-SNX15 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000040764 187 1401 HDGF PKNOX1 CREB3L1 ARNT AGO1 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B

Genomic Location for ARL2-SNX15 Gene

Chromosome:
11
Start:
65,014,113 bp from pter
End:
65,040,572 bp from pter
Size:
26,460 bases
Orientation:
Plus strand

Genomic View for ARL2-SNX15 Gene

Genes around ARL2-SNX15 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ARL2-SNX15 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ARL2-SNX15 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ARL2-SNX15 Gene

Proteins for ARL2-SNX15 Gene

  • Protein details for ARL2-SNX15 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    V9GYD0
    Recommended name:
    ARL2-SNX15 readthrough (NMD candidate)
    Protein Accession:
    V9GYD0

    Protein attributes for ARL2-SNX15 Gene

    Size:
    113 amino acids
    Molecular mass:
    13176 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ARL2-SNX15 Gene

Post-translational modifications for ARL2-SNX15 Gene

No Post-translational modifications

Other Protein References for ARL2-SNX15 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for ARL2-SNX15 Gene

Domains & Families for ARL2-SNX15 Gene

Protein Domains for ARL2-SNX15 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ARL2-SNX15: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ARL2-SNX15 Gene

Function for ARL2-SNX15 Gene

Gene Ontology (GO) - Molecular Function for ARL2-SNX15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005525 GTP binding IEA --
genes like me logo Genes that share ontologies with ARL2-SNX15: view

Phenotypes for ARL2-SNX15 Gene

genes like me logo Genes that share phenotypes with ARL2-SNX15: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ARL2-SNX15 Gene

Localization for ARL2-SNX15 Gene

Gene Ontology (GO) - Cellular Components for ARL2-SNX15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with ARL2-SNX15: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for ARL2-SNX15 Gene

Pathways & Interactions for ARL2-SNX15 Gene

SuperPathways for ARL2-SNX15 Gene

No Data Available

Interacting Proteins for ARL2-SNX15 Gene

Gene Ontology (GO) - Biological Process for ARL2-SNX15 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007264 small GTPase mediated signal transduction IEA --
genes like me logo Genes that share ontologies with ARL2-SNX15: view

No data available for Pathways by source and SIGNOR curated interactions for ARL2-SNX15 Gene

Drugs & Compounds for ARL2-SNX15 Gene

No Compound Related Data Available

Transcripts for ARL2-SNX15 Gene

mRNA/cDNA for ARL2-SNX15 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for ARL2-SNX15 Gene

No ASD Table

Relevant External Links for ARL2-SNX15 Gene

GeneLoc Exon Structure for
ARL2-SNX15
ECgene alternative splicing isoforms for
ARL2-SNX15

Expression for ARL2-SNX15 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for ARL2-SNX15 Gene

Orthologs for ARL2-SNX15 Gene

This gene was present in the common ancestor of animals.

Orthologs for ARL2-SNX15 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia -- 35
  • 74 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ARL2 35
  • 61 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Arl2 35
  • 61 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 60 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 58 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 38 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 28 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 52 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii arl2 35
  • 54 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta Arf84F 35
  • 50 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea evl-20 35
  • 41 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea CSA.2707 35
  • 54 (a)
OneToMany
Species where no ortholog for ARL2-SNX15 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for ARL2-SNX15 Gene

ENSEMBL:
Gene Tree for ARL2-SNX15 (if available)
TreeFam:
Gene Tree for ARL2-SNX15 (if available)

Paralogs for ARL2-SNX15 Gene

genes like me logo Genes that share paralogs with ARL2-SNX15: view

Variants for ARL2-SNX15 Gene

Sequence variations from dbSNP and Humsavar for ARL2-SNX15 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000042185 -- 65,014,790(+) GTGTG(G/T)GTGTG intron-variant
rs1000117241 -- 65,016,642(+) AGAAC(-/CCTGTGTGTG)CCTGT intron-variant, upstream-variant-2KB
rs1000145233 -- 65,040,295(+) ACTAC(A/G)CCCGG nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs1000221831 -- 65,017,768(+) GAAGA(C/T)AGAGG intron-variant, upstream-variant-2KB
rs1000278734 -- 65,022,366(+) GCTTC(C/T)TAAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ARL2-SNX15 Gene

Variant ID Type Subtype PubMed ID
esv3626667 CNV loss 21293372
esv3626668 CNV gain 21293372
esv3626669 CNV gain 21293372
nsv1113400 CNV deletion 24896259
nsv1113401 CNV deletion 24896259
nsv1122633 CNV deletion 24896259
nsv526181 CNV gain 19592680
nsv983034 CNV duplication 23825009

Relevant External Links for ARL2-SNX15 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ARL2-SNX15

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for ARL2-SNX15 Gene

Disorders for ARL2-SNX15 Gene

Relevant External Links for ARL2-SNX15

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ARL2-SNX15

No disorders were found for ARL2-SNX15 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ARL2-SNX15 Gene

Publications for ARL2-SNX15 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for ARL2-SNX15 Gene

Sources for ARL2-SNX15 Gene

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