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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

ARL2 Gene

protein-coding   GIFtS: 53
GCID: GC11P064781

ADP-ribosylation factor-like 2

 Explore 13 diseases affiliated with
ARL2 via our new
 Human Malady Compendium 
Biological research products
for ARL2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
ADP-Ribosylation Factor-Like 21 2
ARFL21 2
ADP-Ribosylation Factor-Like Protein 22

External Ids:    HGNC: 6931   Entrez Gene: 4022   Ensembl: ENSG000002134657   OMIM: 6011755   UniProtKB: P364043   

Export aliases for ARL2 gene to outside databases

Previous GC identifers: GC11P067297 GC11U900036 GC11P064558 GC11P064559 GC11P064539 GC11P061108


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for ARL2:
This gene encodes a small GTP-binding protein of the RAS superfamily which functions as an ADP-ribosylation factor
(ARF). The encoded protein is one of a functionally distinct group of ARF-like genes. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: ARL2_HUMAN, P36404
Function: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the
rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).
GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates
formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction.
Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of
TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in
the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway
involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle

Gene Wiki entry for ARL2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000011.9  NC_018922.1  NT_167190.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the ARL2 gene promoter:
         RFX1   Tal-1   p53   MAZR   Brachyury   Egr-1   POU3F2   Egr-4   E47   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidARL2 promoter sequence
   Search SABiosciences Chromatin IP Primers for ARL2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ARL2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q13   Ensembl cytogenetic band:  11q13.1   HGNC cytogenetic band: 11q13

ARL2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ARL2 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11P064781:  view genomic region     (about GC identifiers)

Start:
64,781,585 bp from pter      End:
64,789,656 bp from pter
Size:
8,072 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ARL2_HUMAN, P36404 (See protein sequence)
Recommended Name: ADP-ribosylation factor-like protein 2  
Size: 184 amino acids; 20878 Da
Subunit: Found in a complex with ARL2, ARL2BP and SLC25A6. Found in a complex with at least ARL2, PPP2CB, PPP2R1A,
PPP2R2A, PPP2R5E and TBCD. Found in a complex with ARL2, ARL2BP and SLC25A4. The GTP-bound form interacts with PDE6D.
Interacts with ELMOD2. The GTP-bound form interacts with ARL2BP. Interacts, preferentially in its GDP-bound state,
with TBCD. Interacts with UNC119
Subcellular location: Mitochondrion intermembrane space. Cytoplasm, cytoskeleton, centrosome. Nucleus. Cytoplasm.
Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria. The complex formed with ARL2BP,
ARL2 and SLC25A4 is expressed in mitochondria (By similarity). Not detected in the Golgi, nucleus and on the mitotic
spindle. Centrosome-associated throughout the cell cycle. Not detected to interphase microtubules
2 PDB 3D structures from and Proteopedia for ARL2:
3DOE (3D)        3DOF (3D)    
Secondary accessions: Q9BUK8

Explore the universe of human proteins at neXtProt for ARL2: NX_P36404

Post-translational modifications:

  • Not N-myristoylated1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P36404

  • ARL2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001186674.1  NP_001658.2  

    ENSEMBL proteins: 
     ENSP00000246747   ENSP00000436021   ENSP00000432971  

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    ProSpec Recombinant Protein for ARL2
    Uscn Proteins for ARL2

    Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA18234692
    GO:0005737cytoplasm ----
    GO:0005758mitochondrial intermembrane space IDA11809823
    GO:0005794Golgi apparatus ----


    ARL2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    ARL2 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR006689 Small_GTPase_ARF/SAR
     IPR024156 Small_GTPase_ARF
     IPR005225 Small_GTP-bd_dom

    Graphical View of Domain Structure for InterPro Entry P36404

    ProtoNet protein and cluster: P36404

    1 Blocks protein family: IPB006688 ADP-ribosylation factor

    UniProtKB/Swiss-Prot: ARL2_HUMAN, P36404
    Similarity: Belongs to the small GTPase superfamily. Arf family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: ARL2_HUMAN, P36404
    Function: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the
    rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP).
    GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates
    formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction.
    Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of
    TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in
    the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway
    involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle

         Genatlas biochemistry entry for ARL2:
    ADP-ribosylation factor-like 2,low molecular weight GTP binding protein,widely expressed,Ras superfamily member

    miRNA
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    hsa-miR-3152-3p hsa-miR-15a hsa-miR-497 hsa-miR-214 hsa-miR-424 hsa-miR-195 hsa-miR-16 hsa-miR-761
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity IMP10831612
    GO:0005095GTPase inhibitor activity TAS10831612
    GO:0005515protein binding IPI19368893
    GO:0005525GTP binding IMP10831612
    GO:0019003GDP binding IEA--


    ARL2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for ARL2:
     Decreased Hepatitis C virus re 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ARL2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/19 Interacting proteins for ARL2 (P364042, 3 ENSP000002467474) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UNC119Q134322, 3, ENSP000003370404MINT-6602303 MINT-6602204 I2D: score=5 STRING: ENSP00000337040
    TBCDQ9BTW92, 3, ENSP000003477194MINT-6602322 I2D: score=4 STRING: ENSP00000347719
    PDE6DO439242, 3, ENSP000002876004MINT-6602195 MINT-6602297 I2D: score=8 STRING: ENSP00000287600
    BSNDQ8WZ552, 3, ENSP000003603124MINT-6602213 I2D: score=1 STRING: ENSP00000360312
    ARL2BPQ9Y2Y03, ENSP000002192044I2D: score=3 STRING: ENSP00000219204
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006184GTP catabolic process IMP10831612
    GO:0007021tubulin complex assembly TAS10831612
    GO:0007049cell cycle IEA--
    GO:0007264small GTPase mediated signal transduction IEA--
    GO:0010811positive regulation of cell-substrate adhesion ISS--


    ARL2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    ARL2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for ARL2
    2 Novoseek chemical compound relationships for ARL2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    adp 58.7 11 17188265 (2), 19829707 (2), 15372247 (1), 18818514 (1) (see all 6)
    gtp 34.6 2 10488091 (1), 10831612 (1)

    Search CenterWatch for drugs/clinical trials and news about ARL2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for ARL2 gene (2 alternative transcripts): 
    NM_001199745.1  NM_001667.3  

    Unigene Cluster for ARL2:

    ADP-ribosylation factor-like 2
    Hs.502836  [show with all ESTs]
    Unigene Representative Sequence: FY212653
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000246747(uc001och.4 uc021qlc.1) ENST00000524585(uc010rnu.2)
    ENST00000529384 ENST00000533729 ENST00000531533 ENST00000529254

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    hsa-miR-3152-3p hsa-miR-15a hsa-miR-497 hsa-miR-214 hsa-miR-424 hsa-miR-195 hsa-miR-16 hsa-miR-761
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    Inhib. RNA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ARL2

    Additional cDNA sequence: 

    AF493888.1 AK223502.1 AK294580.1 BC002530.2 BT006674.1 L13687.1 

    10 DOTS entries:

    DT.446007  DT.100828285  DT.113150  DT.40189101  DT.92433250  DT.95251277  DT.95070897  DT.95251280 
    DT.75179506  DT.95296513 

    24/324 AceView cDNA sequences (see all 324):

    T29292 NM_147777 BC002530 BU730115 AW190262 BM695030 BE279801 BQ957603 
    BQ691172 CB109435 AJ346501 AW297877 CR595019 BC012767 BE140389 CB156380 
    AA333945 BM853836 AA325070 NM_013306 CR614003 BX111746 AI631767 BC014520 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    ARL2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GCGGGAGGGC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See ARL2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for ARL2

    SOURCE GeneReport for Unigene cluster: Hs.502836
        SABiosciences Custom PCR Arrays for ARL2
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for ARL2 gene from 7/36 species (see all 36)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia ARL26
    --
    89(a)
    1 ↔ 1
    GL344077.1(69729-74354)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.115052 Xenopus laevis transcribed sequence with moderate similarity more 77.58(n)    BX853277.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.137682 Transcribed sequence with moderate similarity to protein more 73.69(n)    CK352276.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Arf84F1 , 3 protein amino acid ADP-ribosylation GTP
    binding3
    ADP ribosylation factor 84F1
    75(a)3
    67.03(n)1
    75.54(a)1
      84F133
    409931  NM_057538.31  NP_476886.11 
    worm
    (Caenorhabditis elegans)
    Secernentea evl-201 , 3 GTP-binding ADP-ribosylation factor3
    Protein EVL-201
    61(a)3
    56.7(n)1
    62.5(a)1
      II(8444128-8445068)3
    1916321  NM_063378.11  NP_495779.11 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons TTN51 ADP-ribosylation factor-like 2 61.96(n)
    64.67(a)
      816354  NM_127396.3  NP_179430.1 
    rice
    (Oryza sativa)
    Liliopsida Os.117942 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 69.25(n)    AK073532.1 


    ENSEMBL Gene Tree for ARL2 (if available)
    TreeFam Gene Tree for ARL2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for ARL2 gene
    ARL152  ARL8A2  ARL8B2  ARL32  
    18/30 SIMAP similar genes for ARL2 using alignment to 2 protein entries:     ARL2_HUMAN (see all proteins) (see all similar genes):
    ARL17B    TRIM23    ARL3    ARF3    ARF5    ARF1
    ARF4    ARL9    ARL14    ARL8B    ARL4C    ARL7
    ARL1    ARF6    ARL8A    ARL6    SAR1B    SARA1

    ARL2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ARL2
    PGOHUM00000257892


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/189 NCBI SNPs in ARL2 are shown (see all 189    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs773206871,2
    C,F,--64779612(+) CAGACA/TATTTC 3 -- us2k15Minor allele frequency- T:0.24WA CSA NA 243
    rs768383741,2
    C,F,--64779672(+) CTCCTG/CGGTTG 3 -- us2k14Minor allele frequency- C:0.05WA CSA NA 242
    rs1825198971,2
    --64779706(+) TTGTAC/TTTTTT 3 -- us2k10--------
    rs1459795461,2
    --64779973(+) TGCAGC/TGCCAG 3 -- us2k10--------
    rs1872234631,2
    --64780080(+) ACTCTA/GTCACC 3 -- us2k10--------
    rs1906818521,2
    --64780190(+) GGTGCC/TGCCAC 3 -- us2k10--------
    rs2013406131,2
    --64780330(+) GCCAT-/GG    
       CGCCC
    GGCCA
    3 -- us2k10--------
    rs1170724061,2
    --64780394(+) CGATAT/GGCTCA 3 -- us2k11Minor allele frequency- G:0.01EA 120
    rs171465751,2
    C,F,H,--64780509(+) TGCAAG/AATGGG 3 -- us2k115Minor allele frequency- A:0.04NA NS EA CSA 1804
    rs1146790421,2
    F,--64780710(+) AAGTGC/AGTTGC 3 -- us2k11Minor allele frequency- A:0.02WA 118

    HapMap Linkage Disequilibrium report for ARL2 (64781585 - 64789656 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for ARL2: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    ARL2 for disorders           About GeneDecksing

    OMIM gene information: 601175    OMIM disorders: --

    13 diseases for ARL2:    About MalaCards
    retinitis pigmentosa-2    spastic paraplegia    hereditary spastic paraplegia    multiple endocrine neoplasia
    retinitis pigmentosa    paraplegia    spasticity    retinitis
    cholera    breast cancer    immunodeficiency    malaria
    neuronitis


    Export disorders for ARL2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for ARL2 gene, integrated from 9 sources (see all 48):
    (articles sorted by number of sources associating them with ARL2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Selective amplification of additional members of the ADP-ribosylation factor (ARF) family: cloning of additional human and Drosophila ARF- like genes. (PubMed id 8415637)1, 2, 3 Clark J....Kahn R.A. (1993)
    2. ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin. (PubMed id 10831612)1, 2, 9 Bhamidipati A....Cowan N.J. (2000)
    3. ARL2 and BART enter mitochondria and bind the adenine nucleotide transporter. (PubMed id 11809823)1, 2, 9 Sharer J.D.... Kahn R.A. (2002)
    4. Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity. (PubMed id 20740604)1, 2 Tian G.... Cowan N.J. (2010)
    5. Crystal structure of the ARL2-GTP-BART complex reveal s a novel recognition and binding mode of small GTPase with effector. (PubMed id 19368893)1, 2 Zhang T....Ding J. (2009)
    6. Specificity of Arl2/Arl3 signaling is mediated by a ternary Arl3- effector-GAP complex. (PubMed id 18588884)1, 2 Veltel S.... Wittinghofer A. (2008)
    7. Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry. (PubMed id 18781797)1, 2 Meierhofer D.... Kaiser P. (2008)
    8. BART is essential for nuclear retention of STAT3. (PubMed id 18234692)1, 2 Muromoto R....Matsuda T. (2008)
    9. Arl2 and Arl3 regulate different microtubule-dependent processes. (PubMed id 16525022)1, 2 Zhou C.... Kahn R.A. (2006)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 402 HGNC: 693 AceView: ARL2andSNX15 Ensembl:ENSG00000213465 euGenes: HUgn402
    ECgene: ARL2 H-InvDB: ARL2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for ARL2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for ARL2 gene:
    Search GeneIP for patents involving ARL2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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